Evaluating Cholinergic Receptor Expression in Guinea Pig Primary Auditory and Rostral Belt Cortices After Noise Damage Using [H]Scopolamine and [F]Flubatine Autoradiography by Taylor J. Forrest MS, Timothy J. Desmond MS, Mohamad Issa MD, Peter J. H. Scott PhD, Gregory J. Basura MD, PhD

“…Noise-induced hearing loss leads to anatomic and physiologic changes in primary auditory cortex (A1) and the adjacent dorsal rostral belt (RB). …”
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Neuroplastic Effects of Combined Computerized Physical and Cognitive Training in Elderly Individuals at Risk for Dementia: An eLORETA Controlled Study on Resting States by Charis Styliadis, Panagiotis Kartsidis, Evangelos Paraskevopoulos, Andreas A. Ioannides, Panagiotis D. Bamidis

“…A significant training effect was identified only after the combined training scheme: a decrease in the post- compared to pre-training activity of precuneus/posterior cingulate cortex in delta, theta, and beta bands. This effect was correlated to improvements in cognitive capacity as evaluated by MMSE scores. …”
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Identification of Two Novel Mutations of ABCD1 Gene in Pedigrees with X-Linked Adrenoleukodystrophy and Review of the Literature by Bingzi Dong, Wenshan Lv, Lili Xu, Yuhang Zhao, Xiaofang Sun, Zhongchao Wang, Bingfei Cheng, Zhengju Fu, Yangang Wang

“…The dysfunction of ALD protein, a peroxisomal ATP-binding cassette transporter, results in the excessive saturated very long-chain fatty acids (VLCFAs) accumulation in organs including the brain, spine, and adrenal cortex. X-ALD is characterized as the childhood, adolescent, adult cerebral ALD, adrenomyeloneuropathy (AMN), adrenal insufficiency, and asymptomatic phenotypes, exhibiting a high variety of clinical neurological manifestations with or without adrenocortical insufficiency. …”
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Brain-wide activation involved in 15 mA transcranial alternating current stimulation in patients with first-episode major depressive disorder by Jie Wang, Qing Xue, Wenfeng Zhao, Huang Wang, Haixia Leng, Mao Peng, Xiukun Jin, Liucen Tan, Keming Gao, Hongxing Wang, Baoquan Min

“…Background Although 15 mA transcranial alternating current stimulation (tACS) has a therapeutic effect on depression, the activations of brain structures in humans accounting for this tACS configuration remain largely unknown.Aims To investigate which intracranial brain structures are engaged in the tACS at 77.5 Hz and 15 mA, delivered via the forehead and the mastoid electrodes in the human brain.Methods Actual human head models were built using the magnetic resonance imagings of eight outpatient volunteers with drug-naïve, first-episode major depressive disorder and then used to perform the electric field distributions with SimNIBS software.Results The electric field distributions of the sagittal, coronal and axial planes showed that the bilateral frontal lobes, bilateral temporal lobes, hippocampus, cingulate, hypothalamus, thalamus, amygdala, cerebellum and brainstem were visibly stimulated by the 15 mA tACS procedure.Conclusions Brain-wide activation, including the cortex, subcortical structures, cerebellum and brainstem, is involved in the 15 mA tACS intervention for first-episode major depressive disorder. …”
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The Plasticity of Brain Gray Matter and White Matter following Lower Limb Amputation by Guangyao Jiang, Xuntao Yin, Chuanming Li, Lei Li, Lu Zhao, Alan C. Evans, Tianzi Jiang, Jixiang Wu, Jian Wang

“…In amputees, a thinning trend was seen in the left premotor cortex (PMC). Smaller clusters were also noted in the visual-to-motor regions. …”
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The Short-Term Effects of Transcranial Direct Current Stimulation on Electroencephalography in Children with Autism: A Randomized Crossover Controlled Trial by Anuwat Amatachaya, Mark P. Jensen, Niramol Patjanasoontorn, Narong Auvichayapat, Chanyut Suphakunpinyo, Suparerk Janjarasjitt, Niran Ngernyam, Benchaporn Aree-uea, Paradee Auvichayapat

“…Twenty male children with autism were randomly assigned in a crossover design to receive a single session of both active and sham tDCS stimulation (11 mA) over F3 (left dorsolateral prefrontal cortex). Pre- to postsession changes in a measure of cortical activity impacted by tDCS (PAF) and ATEC were compared between groups. …”
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Feasibility of Cognitive Training in Combination With Transcranial Direct Current Stimulation in a Home-Based Context (TrainStim-Home): study protocol for a randomised controlled t... by Ulrike Grittner, Agnes Flöel, Rafal Nowak, Friederike Thams, Daria Antonenko, Merle Rocke, Robert Malinowski

“…Thirty healthy participants, aged 60–80 years, will receive 2 weeks of combined cognitive training and anodal tDCS over left dorsolateral prefrontal cortex (target intervention), compared with cognitive training plus sham stimulation. …”
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Benefits of Repetitive Transcranial Magnetic Stimulation (rTMS) for Spastic Subjects: Clinical, Functional, and Biomechanical Parameters for Lower Limb and Walking in Five Hemipa... by Luc Terreaux, Raphael Gross, Fabien Leboeuf, Hubert Desal, Olivier Hamel, Jean Paul Nguyen, Chantal Pérot, Kévin Buffenoir

“…We conducted a prospective, randomized, double-blind crossover study on five spastic hemiparetic patients to determine whether this type of stimulation of the premotor cortex can provide a clinical benefit. Material and Methods. …”
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Acupuncture Induces Reduction in Limbic-Cortical Feedback of a Neuralgia Rat Model: A Dynamic Causal Modeling Study by Zhen-Zhen Ma, Ye-Chen Lu, Jia-Jia Wu, Xiang-Xin Xing, Xu-Yun Hua, Jian-Guang Xu

“…In both groups, DCM revealed that noxious stimuli were most likely driven by the somatosensory cortex, with bidirectional propagation with the hypothalamus and amygdala and the interactions in them. …”
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Sensorimotor Dysfunction Following Anterior Cruciate Ligament Reconstruction- an Afferent Perspective: A Scoping Review by Thilina N Vitharana, Enda King, Kieran Moran

“…The function of somatosensory and visual systems was assessed across both central processing (processing of information in the central cortex) and local processing (all other assessments outside of central processing of information)…”
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Modulation of Motor Cortical Activities by Action Observation and Execution in Patients with Stroke: An MEG Study by Jun-Ding Zhu, Chia-Hsiung Cheng, Yi-Jhan Tseng, Chien-Chen Chou, Chih-Chi Chen, Yu-Wei Hsieh, Yu-Hsien Liao

“…Twenty patients with stroke and 20 healthy controls were recruited for the collection of data on the beta oscillatory activity in the primary motor cortex (M1). All participants performed the conditions of resting, observation only, and video observation combined with execution (video AOE). …”
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Interleukin-22 Plays a Protective Role by Regulating the JAK2-STAT3 Pathway to Improve Inflammation, Oxidative Stress, and Neuronal Apoptosis following Cerebral Ischemia-Reperfusio... by Yongfei Dong, Chengyun Hu, Chunxia Huang, Jie Gao, Wanxiang Niu, Di Wang, Yang Wang, Chaoshi Niu

“…IL-22 treatment remarkably reduced the expression of inflammatory cytokines, including IL-1β, monocyte chemotactic protein- (MCP-) 1, and tumor necrosis factor- (TNF-) α, both in serum and the ischemic cerebral cortex. In addition, IL-22 treatment also decreased oxidative stress and neuronal apoptosis in mice after cerebral I/R injury. …”
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Altered Intrinsic Coupling between Functional Connectivity Density and Amplitude of Low-Frequency Fluctuation in Mild Cognitive Impairment with Depressive Symptoms by Xiaozheng Liu, Jiuzun Chen, Bangli Shen, Gang Wang, Jiapeng Li, Hongtao Hou, Xingli Chen, Zhongwei Guo, Chuanwan Mao

“…The results showed that the ALFF values in the D-MCI group were higher in the left medial prefrontal cortex (mPFC) and lower in the right precentral gyrus (preCG), and the FCD values were higher in the left medial temporal gyrus (MTG) than those in the nD-MCI group. …”
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Electroacupuncture Treatment Alleviates the Remifentanil-Induced Hyperalgesia by Regulating the Activities of the Ventral Posterior Lateral Nucleus of the Thalamus Neurons in Rats by Hong-Yan Zhao, Ling-Yu Liu, Jie Cai, Yan-Jun Cui, Guo-Gang Xing

“…The ventral posterior lateral nucleus (VPL) of the thalamus, a key relay station for the transmission of nociceptive information to the cerebral cortex, is activated by RF infusion. Electroacupuncture (EA) is an effective method for the treatment of pain. …”
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Time-lapse imaging of identified granule cells in the mouse dentate gyrus after entorhinal lesion in vitro reveals heterogeneous cellular responses to denervation by Davide Greco, Alexander Drakew, Nina Rößler, Nina Rößler, Tassilo Jungenitz, Peter Jedlicka, Peter Jedlicka, Thomas Deller

“…The effects of denervation on neurons can be readily studied in vitro using organotypic slice cultures of entorhinal cortex and hippocampus. Following transection of the entorhino-dentate projection, granule cells (GCs) are denervated and show on average a transient loss of spines on their denervated distal dendrites but not on their non-denervated proximal dendrites. …”
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Neuromodulation of Attentional Control in Major Depression: A Pilot DeepTMS Study by Jodie Naim-Feil, John L. Bradshaw, Dianne M. Sheppard, Oded Rosenberg, Yechiel Levkovitz, Pinhas Dannon, Paul B. Fitzgerald, Moshe Isserles, Abraham Zangen

“…This study examined whether acute and long-term high-frequency repetitive deepTMS to the dorsolateral prefrontal cortex (DLPFC) can attenuate attentional deficits associated with MDD. …”
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Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress by Alexandre Champroux, Mitra Sadat-Shirazi, Xuan Chen, Jonathan Hacker, Yongjie Yang, Larry A. Feig

“…We found that CSI stress decreases miR-34c carried by A-Exos in the prefrontal cortex and amygdala, as well as in the blood of males. …”
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Magnetic Resonance Imaging of Bacterial Meningoencephalitis in a Foal by Judit Viu, Lara Armengou, Cristian de la Fuente, Carla Cesarini, Sònia Añor, Eduard Jose-Cunilleras

“…Diffuse hyperintensity was also identified in the left cerebellar cortex on T2WI. Neither mass effect nor cerebral midline shift were identified. …”
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Altered cortical network dynamics during observing and preparing action in patients with corticobasal syndrome by Marius Krösche, Christian J. Hartmann, Markus Butz, Alfons Schnitzler, Jan Hirschmann

“…This reduction was evident bilaterally in superior parietal, primary motor, premotor and inferior frontal cortex. During movement preparation, beta power suppression was also reduced in CBS patients, correlating with longer reaction times. …”
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Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease by A. Ahnaou, C. Walsh, N. V. Manyakov, S. A. Youssef, W. H. Drinkenburg

“…The present results demonstrate early dysfunctional hippocampal networks, despite no spreading tau pathology to the hippocampus and frontal cortex. The ability of the K18 seed in the brainstem LC to elicit such robust functional alterations in distant hippocampal structures in the absence of pathology challenges the classic view that tau pathology spread to an area is necessary to elicit functional impairments in that area.…”
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