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1601
Biomarker discovery and phytochemical interventions in Alzheimer's disease: A path to therapeutic advances
Published 2025-02-01“…Methods: A differential expression analysis was conducted using GEO2R, where the significant differentially expressed genes (DEGs) were identified in brain areas that include the Entorhinal Cortex (EC) and Posterior Cingulate (PC), as well as in peripheral blood. …”
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1602
The Studies of Chlorogenic Acid Antitumor Mechanism by Gene Chip Detection: The Immune Pathway Gene Expression
Published 2013-01-01“…Chlorogenic acid (CA), extracted from folium cortex eucommiae, has been confirmed to have lots of biological activities encompassing inhibition of tumor. …”
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1603
Dose Effect Evaluation and Therapeutic Window of the Neuro-EPO Nasal Application for the Treatment of the Focal Ischemia Model in the Mongolian Gerbil
Published 2012-01-01“…The Neuro-EPO in a rate of 249.4 UI every 8 hours for 4 days showed 25% higher viability efficacy (𝑃>0.01), improving neurological score and behavior of the spontaneous exploratory activity, the preservation of CA3 areas of the hippocampus, the cortex, and thalamic nuclei in the focal ischemia model of the Mongolian gerbil. …”
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1604
A novel FPGA‐Based Bi input‐reduced order extended Kalman filter for speed‐sensorless direct torque control of induction motor with constant switching frequency controller
Published 2021-05-01“…The full precision single floating point numbers in the IEEE 754 standard are used during the implementation of the HIL emulator which contains closed‐loop speed‐sensorless drive system of IM on the Xilinx Virtex XC5VLX‐110T ML506 FPGA board. In this HIL emulator of speed‐sensorless IM drive system, stator stationary axis components of stator flux, rotor mechanical angular speed, load torque, stator and rotor resistances are estimated with the novel BI‐ROEKF which is proposed for the first time in the literature. …”
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1605
A performance-based generative design framework based on a design grammar for high-rise office towers during early design stage
Published 2025-02-01“…Therefore, targeting the geometric characteristics of high-rise office towers, a systematically developed and universally applicable design grammar, named “Vertex-Based Polygonal Generative Grammar (VPGG)” is proposed. …”
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1606
Neutralization by Insulin of the Hypertensive Effect of Dermcidin Isoform 2: An Environmentally Induced Diabetogenic and Hypertensive Protein
Published 2014-01-01“…Incubation of kidney cortex cells with 0.2 μM dermcidin-inhibited synthesis of (r)-cortexin, an antihypertensive protein, and the basal (r)-cortexin level was reduced from 33 nM to 15 nM. …”
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1607
Multi-target combination treatment with rTMS and tDCS for Tourette syndrome: a case report
Published 2025-01-01“…Here, we report a case of refractory TS, in which low-frequency rTMS was delivered to the left supplementary motor area (SMA), combined with tDCS targeting the primary motor cortex (M1) and the cerebellum, with the cathode positioned over the right M1 and the anode over the left cerebellum. …”
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1608
Clinical Comparison between HD-tDCS and tDCS for Improving Upper Limb Motor Function: A Randomized, Double-Blinded, Sham-Controlled Trial
Published 2024-01-01“…This study aimed to investigate whether high-definition transcranial direct current stimulation (HD-tDCS) of the primary motor cortex (M1) functional area in poststroke patients in the subacute phase is more effective in improving upper limb function than conventional tDCS. …”
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1609
Diffusion MRI Findings in Encephalopathy Induced by Immunosuppressive Therapy after Liver Transplantation
Published 2020-01-01“…At clinical onset, DWI showed hyperintensity of the temporo-parieto-occipital cortex with normal ADC values in the patient with following good clinical recovery and decreased values in the other one; in the latter case, MRI abnormalities were still present after ten days, until the patient’s exitus. …”
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1610
Petroselinum crispum extract ameliorates scopolamine-induced cognitive dysfunction: role on apoptosis, inflammation and oxidative stress
Published 2022-09-01“…Scopolamine reduced M1 receptor expression, Bcl-2/Bax ratio, and glutathione levels in the hippocampus and frontal cortex, while malondialdehyde levels, caspase-3/9 expressions, and acetylcholinesterase (AChE) activity were found to be increased. …”
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1611
Expression of palmitoyl transferases in brain structures of mice genetically predisposed to depressive-like behavior
Published 2018-08-01“…One of them was visualized at 27 kDa in the frontal cortex and midbrain. The other, at 32 kDa in the hippocampus. …”
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1612
Intronic SNP in ESR1 encoding human estrogen receptor alpha is associated with brain ESR1 mRNA isoform expression and behavioral traits.
Published 2017-01-01“…We have searched for regulatory variants affecting ESR1 expression in human brain, measuring allelic ESR1 mRNA expression in human brain tissues with marker SNPs in exon4 representing ESR1-008 (or ESRα-36), and in the 3'UTR of ESR1-203, two main ESR1 isoforms in brain. In prefrontal cortex from subjects with bipolar disorder, schizophrenia, and controls (n = 35 each; Stanley Foundation brain bank), allelic ESR1 mRNA ratios deviated from unity up to tenfold at the exon4 marker SNP, with large allelic ratios observed primarily in bipolar and schizophrenic subjects. …”
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1613
Taking into account students' psychotypes and using their neuropsychological maps when implementing digital educational technologies within the Metaverse
Published 2025-02-01“…It was revealed that learning using digital online technologies in the context of the Metaverse has a positive effect on the development of the mobility of neural processes, and cognitive and psychophysiological mechanisms, increases the involvement and motivation of students to acquire new knowledge, helps to normalize the balance between the psychophysiological processes of excitation and inhibition, activates the areas of the cerebral cortex responsible for will, emotions, self-awareness, motivation and communication, contributes to the development of communicative competence, critical thinking and creative potential of the student's personality. …”
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1614
Boy’s love fans versus non-fans in the sexual identity and neural response in the digital age’s young females
Published 2025-01-01“…The research leads to the conclusion that long term exposed to Boys’ Love may decrease the reward sensitivity to BL stimuli and weakens the brain’s response of the right ventrolateral prefrontal cortex (rVLPFC) to BL stimuli.…”
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1615
Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review
Published 2025-02-01“…The role of the cerebellum in motor control, the theoretical underpinnings of cerebellar stimulation on motor cortex excitability, and the indirect effects on cognition and motor learning are explored. …”
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1616
Immunohistochemistry for (Pro)renin Receptor in Humans
Published 2021-01-01“…It was observed in thyroid follicular epithelial cells, hepatic cells, pancreatic duct epithelial cells, zona glomerulosa and zona reticularis of the cortex and medulla of the adrenal gland, proximal and distal tubules and collecting ducts of the kidney, cardiomyocytes, and skeletal muscle cells. …”
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1617
Decoding cortical folding patterns in marmosets using machine learning and large language model
Published 2025-03-01“…Macroscale neuroimaging results have revealed significant differences in the structural and functional connectivity patterns of gyri and sulci in the primate cerebral cortex. Despite these findings, understanding these differences at the molecular level has remained challenging. …”
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1618
Abnormal Functional Connectivity of Ventral Anterior Insula in Asthmatic Patients with Depression
Published 2017-01-01“…In addition, compared with HCs, the DA and NDA patients both exhibited increased FC between the left vAI and the right anterior cingulate cortex (ACC), decreased FC between the left vAI and the bilateral parietal lobe, and increased FC between the right vAI and the left putamen and the right caudate, respectively. …”
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1619
Effect of vasopressin on the expression of genes for key enzymes of interstitial hyaluronan turnover and concentration ability in WAG rat kidneys
Published 2016-05-01“…The V2 receptor-selective vasopressin analog dDAVP (100 μg/kg bw, ip, twice a day for 2 days) induced a considerable decrease in Has2 mRNA content in the papilla with less pronounced changes in the cortex. In contrast to Has2, dDAVP treatment caused a significant increase in Hyal1 and Hyal2 mRNA content in the renal papilla. …”
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1620
Investigating the efficacy of transcranial direct current stimulation on chronic pain management in endometriosis patients: A randomized controlled trial protocol.
Published 2024-01-01“…Anodal tDCS will be delivered at an intensity of 2mA, applied over the primary motor cortex for 20 minutes per day for 10 consecutive days. …”
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