KDM6A facilitates Xist upregulation at the onset of X inactivation by Josephine Lin, Jinli Zhang, Li Ma, He Fang, Rui Ma, Camille Groneck, Galina N. Filippova, Xinxian Deng, Chizuru Kinoshita, Jessica E. Young, Wenxiu Ma, Christine M. Disteche, Joel B. Berletch

“…Results We observed impaired upregulation of Xist and reduced coating of the Xi during early stages of differentiation in Kdm6a KO cells, both homozygous and heterozygous, suggesting a threshold effect of KDM6A. …”
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Evaluasi Usability Website Berita Online Prokal.Co Menggunakan Evaluasi Heuristic dan Webuse by M. Gilvy Langgawan Putra, Nisya Rani Sabilla, Sri R. Natasia

“…This research was conducted with 5 main stages, those are establishing requirements to find usability problems, design alternatives to design the improvements with the form of design ideas, protoyping to implement and build designs, evaluating to evaluate the prototype results, and conclusions. …”
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A retrospective study of pembrolizumab combined with XELOX regimen in the treatment of advanced gastric cancer by FENG Huizhi, LIU Jingmei, BU Xiaoqian

“…Inclusion criteria: patients with HER2-negative, untreated advanced gastric cancer or adenocarcinoma of the esophagogastric junction, confirmed by clinical histopathological examination and meeting relevant diagnostic criteria; TNM stage Ⅳ; age ≥20 years; expected survival ≥6 months; no severe organ damage before treatment; Karnofsky score >60; patients with complete clinical data. …”
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Whole-Genome Methylation Sequencing Analysis and Functional Verification of LIM-Homeobox Family Genes in Cervical Cancer by Yu R, Yu Q, Shi J, Meng X, Deng Z, Suo J, Yang H

“…The study focused on the methylation changes of LHX2, LHX5, and LHX9 genes, assessing their expression levels using qRT-PCR and correlating these changes with cervical cancer stages.Results: MCG was the main way of genomic DNA methylation in the three patients. …”
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Gas drainage and utilization in coal mines in China: History, technological advances, and prospects by Guofu LI, Chao LI, Bichuan ZHANG, Yun XU, Zheng WANG, Xianjun ZHOU

“…Advancement The period from the 1930s to the 1950s represents the initial stage of gas pumping in coal mines in China. During this period, underground drilling was employed for gas pumping in target coal seams and their upper adjacent strata to ensure mining safety in the Fushun mining area in Liaoning Province, the Yangquan mining area in Shanxi Province, and the Tianfu mining area in Chongqing City. …”
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Contribution à l’étude de la mobilité de l’hallux et de la phylogénie des primates actuels by J Norbert Kuhlmann

“…They are the landmarks, which allow imagining the different stages of the evolution of non-human primates to Homosapiens. …”
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An exploratory study of INPP4B, a biomarker of gemcitabine chemoresistance in pancreatic cancer by REN Jiaqiang, WU Shuai, SU Tong, LI Jie, HAN Liang, WU Zheng

“…Background and purpose: Pancreatic cancer is a highly aggressive solid tumor of the digestive system, with radical resection being unfeasible in approximately 80% of patients due to the absence of specific clinical manifestations in the early stages. The use of gemcitabine as a first-line chemotherapeutic agent has not significantly improved patient prognosis, primarily due to the development of chemoresistance. …”
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Twin to Twin Transfusion Syndrom by Yusrawati ., Rika Effendy

“…Case2: a woman 31 years old with diagnose MP5 term parturient in second stage of labour with, gemelli. The babies were born spontaneously. …”
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Construction of a prognostic model for gastric cancer based on immune infiltration and microenvironment, and exploration of MEF2C gene function by Si-yu Wang, Yu-xin Wang, Lu-shun Guan, Ao Shen, Run-jie Huang, Shu-qiang Yuan, Yu-long Xiao, Li-shuai Wang, Dan Lei, Yin Zhao, Chuan Lin, Chang-ping Wang, Zhi-ping Yuan

“…Second, regardless of the T or N staging, the low ICI Score group had significantly higher overall survival (OS) compared to the high ICI Score group. …”
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從「無感」到「五感」的環境意識啟蒙：特定場域劇場教學之批判教育學實踐 From “Indifference” to Environmental Conscientization Through Critical Sensory Pedagogy: A Critical Pedagogy Praxis in a University Site-Specifi... by 藍貝芝 Betsy Lan, 楊佳羚 Chia-Ling Yang

“…By the semester’s end, students demonstrated a deepened critical consciousness of environmental injustice, staging sitespecific theatre performances that emphasized the importance of local initiatives in addressing climate change. …”
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Analysis of cervical and breast cancer screening behavior and its influencing factors among urban and rural women in Beijing. by Yanqing Gao, Guoxin Liang, Chun Chang, Feng Pan, Fumin Huang, Litong Gong, Liyu Huang

“…<h4>Methods</h4>This study used a multi-stage stratified random sampling method to select 4, 000 women in urban and rural areas of Beijing to analyze their behavior, basic situation, and influencing factors regarding cervical and breast cancer screening.…”
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Analisa Strategi Teknologi Informasi Pemasaran UKM Kuliner di Media Sosial Menggunakan Metode SWOT by Fahmi Ajismanto, Andika Widyanto

“…Qualitative data in this research is the form of questions asked to respondents using a questionnaire, then the data are quantified for in depth analysis. The stages are from weighting and rating every item in questionneire, IFAS and EFAS calculations, Cartesian SWOT diagrams, combined strategy matrice, and SWOT matrices. …”
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Metode Entropy-SAW dan Metode Entropy-WASPAS dalam Menentukan Promosi Jabatan Bagi Karyawan Terbaik di Cudo Communications by Sarwati Rahayu, Ahmad Juang Teguh Gumilang, Oktia Putri Bharodin, Firya Faturahman

“…Therefore, 6 people who continued to the assessment stage namely Muhammad Ridwan, Dirly Try Andhika, Keysa Dwilingga, Kelvin Dylan Hensen, Nesya Ayu Wulandari, and Yusuf Rizqi Ramanka. …”
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بررسی تاثیر وسایل الکترونیکی بر رشد مهارت های زبانی، شناختی و حرکتی کودکان و نوپایان در مراکز بهداشتی دانشگاه علوم پزشکی تهران... by نرگس فدایی, هوشنگ دادگر, آتوسا معین افشار, حسین درگاهی, غزال شریغت پناهی, اکرم عزتی فرد, حجت ابراهیمی نیک

“…ابزار این پژوهش را پرسشنامه های رشد کودک(Ages and Stages Questionnaires; ASQ) و فهرست واژگان MacArthur-Bates تشکیل می داد که روایی صوری و محتوی آن تایید گردید. …”
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Perancangan User Experience Aplikasi Penghemat Listrik myECO dengan Otomatisasi dan Manajemen Listrik untuk Rumah Tangga by Maulana Derifato Achmad, Herman Tolle, Buce Trias Hanggara

“…In designing the myECO application using the Design Thinking and Lean Startup methods, each method is divided into several stages including the Design Thinking method to understand user needs, summarize the needs of users, and to design ideas for solutions to problems. …”
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Guías impresas en 3D: ¿mejoran el control local y la supervivencia global en el tratamiento de los sarcomas pélvicos? Estudio de validación clínica by T. Fernández-Fernández, L. Mediavilla-Santos, M. Cuervo-Dehesa, E. Gómez-Larrén, R. Pérez-Mañanes, J. Calvo-Haro

“…Demographic and clinical data, including tumor histology, stage, resection technique, associated reconstruction, adjuvant therapies, and complications, were evaluated. …”
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Risk of All-Cause Mortality in Mild Chronic Obstructive Pulmonary Disease: Evidence From the NHANES III and 2007&ndash;2012 by Zou W, Ou J, Wu F, Xiao S, Deng Z, Li H, Wang Z, Tang G, Liu S, Ye D, Zhu D, Hu J, Ran P

“…Weifeng Zou,1,2,&ast; Jie Ou,1,2,&ast; Fan Wu,3,4,&ast; Shan Xiao,5 Zhishan Deng,3 Haiqing Li,3 Zihui Wang,3 Gaoying Tang,3 Shuling Liu,1 Dong Ye,6 Dongshuang Zhu,2 Jinxing Hu,1 Pixin Ran3,4 1State Key Laboratory of Respiratory Disease, Guangzhou Chest Hospital, Guangzhou, People’s Republic of China; 2Department of Pulmonary and Critical Care Medicine, Shufu County People’s Hospital, Kashgar region, Xinjiang, People’s Republic of China; 3State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Clinical Research Center for Respiratory Disease & National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China; 4Guangzhou National Laboratory, Guangzhou, People’s Republic of China; 5Department of Pulmonary and Critical Care Medicine, Shenzhen Longgang District Central Hospital, Shenzhen, People’s Republic of China; 6Department of Internal Medicine, Guangdong Province Second People’s Hospital, Guangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fan Wu; Pixin Ran, State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Center for Respiratory Medicine & National Clinical Research Center for Respiratory Disease & The First Affiliated Hospital of Guangzhou Medical University, 195 Dongfeng Xi Road, Guangzhou, 510120, People’s Republic of China, Email wu.fan@vip.163.com; pxran@gzhmu.edu.cnBackground: It is unclear whether patients with Global Initiative for Chronic Obstructive Lung Disease stage 1 (mild) chronic obstructive pulmonary disease (COPD) have a higher risk of all-cause mortality than participants with normal spirometry results.Methods: We used the data from the National Health and Nutrition Examination Survey (NHANES) III and 2007– 2012, which included participants aged 20– 79 years, to investigate whether patients with mild COPD (whole population and subgroups) have a higher risk of all-cause mortality than participants with normal spirometry. …”
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Pengaruh Edible Coating Berbasis Kitosan, Ekstrak Aloe Vera Dengan Penambahan Pektin Jeruk Terhadap Masa Simpan Buah Pir Potong by Muryeti Muryeti, Koulan Sadida

“…This study used a Completely Randomized Design (CRD) with a 2-factor factorial design to test the combination of edible coatings on sliced pears, with quality parameters such as weight loss, pH, and total soluble solids (TSS) over 6 days of storage at room temperature, analyzed using Two-Way ANOVA. The research stages startedwith the preparation of chitosan solution, the manufacture of edible coating from aloe vera, chitosan, pectin and application edible coating on pears. …”
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Oral Administration of 17α-Methyltestosterone Increased Male Percentage of Freshwater Crayfish Cherax quadricarinatus by O. Carman, M.Y. Jamal, . Alimuddin

“…Application of monosex male culture using steroid sex hormone administration method during the period of sex differentiation or early developmental stage might be increased efficiency in farming.  …”
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Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis by Alisha Puri, Anita M. Lloyd, Aminu K. Bello, Marcello Tonelli, Sandra M. Campbell, Karthik Tennankore, Sara N. Davison, Stephanie Thompson

“…Setting &amp; Study Populations: Studies assessing multidimensional frailty tools in adults at any stage of CKD and evaluating a measurement property of interest as per the Consensus-based Standards for the Selection of Health Measurement Instruments taxonomy. …”
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