« Mon seul Shakespeare » by Jacques Nichet

“…I hope these few pages will reflect the real pleasure we all took in staging Shakespeare’s play whose text so generously rewards those who approach it with a form of innocence!…”
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Services availability and readiness assessment of adolescent sexual and reproductive health in primary healthcare facilities: evidence from selected districts in Ghana by Michel Adurayi Amenah, Jacob Novignon, Ama Pokuaa Fenny, Irene A. Agyepong, Tim Ensor

“…Methods The study utilized a multi-stage sampling approach to select 67 PHCs across four districts in the Greater Accra region, reflecting Ghana's broad demographic diversity. …”
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Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the Che... by Enriqueta Felip, David P. Carbone, Martin Reck, Luis Paz-Ares, Yong Yuan, Nan Hu, Niels Reinmuth, Xiaoqing Zhang, Thomas John, Ying Cheng, Shun Lu, Manuel Cobo, Michael Schenker, Tudor-Eliade Ciuleanu, Stéphanie Bordenave, Oscar Juan-Vidal, Juliana Menezes, Eduardo Richardet, Hideaki Mizutani, Bogdan Zurawski, Aurelia Alexandru, Javed Mahmood, Tuli De, Irene Santi, John R. Penrod, Adam Lee

“…We report updated efficacy and safety in all randomized patients with a minimum 4-year follow-up and an exploratory treatment-switching adjustment analysis in all treated patients who received chemotherapy and subsequent immunotherapy.Methods Adults with stage IV/recurrent non-small cell lung cancer (NSCLC), no sensitizing EGFR/ALK alterations, and ECOG performance status ≤1 were randomized 1:1 to nivolumab 360 mg every 3 weeks plus ipilimumab 1 mg/kg every 6 weeks with chemotherapy (two cycles) or chemotherapy (four cycles, with optional maintenance pemetrexed for the nonsquamous population). …”
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Efficacy, safety and cost-effectiveness of obinutuzumab in patients with follicular lymphoma: a rapid review by Chao Wang, Yunzhuo Dong, Peng Men, Ruixia Zhang, Ying Xiao, Yishan Bu, Yinpeng Qin, Xinran Zhang, Qianqian Dou, Yiheng Yang, Huier Gao, Yi Zhang

“…BackgroundObinutuzumab was approved in China in June 2021 used in combination with chemotherapy (followed by obinutuzumab maintenance) for the treatment of adult patients with previously untreated stage II bulky, III, or IV follicular lymphoma (FL). …”
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AI Chatbots and Cognitive Control: Enhancing Executive Functions Through Chatbot Interactions: A Systematic Review by Pantelis Pergantis, Victoria Bamicha, Charalampos Skianis, Athanasios Drigas

“…However, its use in executive skills training is at a primary stage. The findings highlighted the need for a unified framework for reference and future studies, better study designs, diverse populations, larger sample sizes of participants, and longitudinal studies that observe the long-term effects of their use.…”
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Jovens e os Stories do Instagram: estudo netnográfico durante a pandemia da Covid-19 by Alan César Belo Angeluci, Brasilina Passarelli, Carolina Gois Falandes, Milena Possar Garcia

“…A netnography (a variation of online ethnography) was conducted in three stages: participant observation, web scraping, and video interviews with young people aged 15 to 18 in the metropolitan region of São Paulo, following Bardin's Content Analysis. …”
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Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

“…The KEYNOTE 158 trial supported United States Food and Drug Administration (FDA) approval of the Foundation Medicine test (FoundationOneCDx) at TMB≥10 mut/Mb as a companion diagnostic (CDx) for single-agent pembrolizumab in second+line. …”
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Cochlear implantation outcomes in adults: A scoping review. by Isabelle Boisvert, Mariana Reis, Agnes Au, Robert Cowan, Richard C Dowell

“…Systematic searches were conducted in Medline, Embase, Web of Science and Google Scholar. A two-stage screening approach was used, with seven reviewers independently screening titles and abstracts against inclusion criteria and three from this group further reviewing full-texts. …”
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A new prognostic model based on serum apolipoprotein AI in patients with HBV-ACLF and acutely decompensated liver cirrhosis by Ruidong Mo, Zhenglan Zhang, Yanmei Zhou, Yue Wang, Pengbo Yin, Chenxi Zhang, Haoshuang Fu, Cong Qian, Xiaogang Xiang, Rongkun Yin, Qing Xie

“…Results In the cohort, the negatively correlation was found between the Model for End-Stage Liver Disease (MELD) score and serum apoAI levels (r = -0.7946, P < 0.001). …”
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Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus by Saowanee Chamnanya, Benyapa Kiddela, Jassada Saingamsook, Woottichai Nachaiwieng, Nongkran Lumjuan, Pradya Somboon, Jintana Yanola

“…In Cq_SP-R strain, the CYP4H34 and CYP9J34 genes were overexpressed in both stages. The kdr L1014F mutation was found in Cq_SP-R and its parent Cq_SP strains with a significantly higher mutant allele frequency in the survivor mosquitoes than in dead mosquitoes (P < 0.0001). …”
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Deteksi Objek menggunakan Dashboard Camera untuk Sistem Peringatan Pencegah Kecelakaan pada Mobil by Raymond Sutjiadi, Timothy John Pattiasina

“…This application was developed using Object Detection Method in Tensorflow Open Source Machine Learning Library. The research stage was started from problem analysis, literature study to search comparison from previous research, also software development and finalized with testing to measure system performance. …”
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DNA Copy Number Changes at 8q11–24 in Metastasized Colorectal Cancer by T. E. Buffart, J. Coffa, M. A. J. A. Hermsen, B. Carvalho, J. R. M. van der Sijp, B. Ylstra, G. Pals, J. P. Schouten, G. A. Meijer

“…Materials and Methods: Thirty-two cases of colorectal cancer, 10 stage B1, 10 B2 and 12 D (Astler–Coller) with their corresponding liver metastasis and one colorectal cell line (colo205, previously analyzed by array-CGH), were included in this study. …”
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Field Detection and Numerical Simulation Study on Roof Asymmetric Fracture Mechanism of Large-Span Soft Rock Roadway with Discontinuity Surface by Liang Chen, Shouyang Gao, Bin Miao, Nan Yao, Shizhong Zhang, Wei Zhang

“…When the surrounding rock stress is completely released, the roof cracks in region I gradually transition from nonconnected to connected state and form a “quasi-right triangle” loosening zone. …”
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Pathophysiology of tumor progression and possibilities of using polarization biomedical optics methods in the diagnosis of papillary thyroid cancer by Yu.Ye. Rohovyi, O.V. Bilookyi, O.H. Ushenko, V.V. Bilookyi

“…Clinical diagnosis of papillary thyroid cancer usually occurs at the stage of tumor progression accompanied by intensive processes of growth, invasion, formation of blood vessels to provide blood supply to the tumor, the structure and quantitative changes of which can be more informatively accurately assessed by polarization biomedical optics. …”
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Productivity of water and heat resources and cotton yield response to cropping pattern and planting density in cotton fields in arid area by Zhenlin Dong, Sumei Wan, Yunzhen Ma, Jinbin Wang, Lu Feng, Yunlong Zhai, Tiantian Li, Zhengjun Cui, Jian Wang, Beifang Yang, Ze Yang, Zhan Zhao, Fei Yan, Shiwu Xiong, Yabing Li, Guodong Chen

“…Planting density significantly affected soil temperature during flowering and boll-setting stages. Lint and seed cotton yields showed positive correlations with soil heat production efficiency (PEsoil) and negative correlations with water production efficiency (WPc), with optimal patterns observed in the four-row, low-density and six-row, medium-density treatments. …”
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Effects of nitrogen fertilizer basal-to-top-dressing ratios on maize straw decomposition, soil carbon and nitrogen, and bacterial community structure in different soil textures on... by Jingyu Li, Jingyu Li, Xiaonan Yang, Rui Hou, Yujie Ma, Yanqun Wang, Yang Ma, Wenchao Zhen, Yuanyuan Huang, Xin Fu, Zhengping Peng, Zhengping Peng, Mingxin Men

“…At the wheat maturity stage, the decomposition rate of maize straw reached 69.48–75.04%. …”
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Les effets paradoxaux du transfert des forces de sécurité en Tunisie (juin 1955-mars 1956) by Khansa Ben Tarjem

“…In particular, it depended on the structure of the colonised state and the terms of decolonisation (the timing, duration, organisation and intensity of nationalist resistance movements). …”
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Host–virus interactions during infection with a wild-type ILTV strain or a glycoprotein G deletion mutant ILTV vaccine strain in an ex vivo system by Gayathri Gopakumar, Mauricio J.C. Coppo, Andrés Diaz-Méndez, Carol A. Hartley, Joanne M. Devlin

“…This study has revealed that the modifications of transcription of host genes during the early stages of ILTV infection are not limited to changes in cytokine or chemokine gene transcription, but several other immune-related genes and ECM components. …”
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Surgical stimulation of uveoscleral outflow is an alternative to cyclodestructive procedures by E.A. Korchuganova, A.Yu. Kazantzeva

“…In addition, the patients were distributed by age and the stage and type of glaucoma, i.e., 128 patients were diagnosed with POAG and 36 patients were diagnosed with secondary thrombotic glaucoma. …”
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Bør krigen i Ukraina påvirke vårt syn på atomvåpen? by Torgeir E. Fjærtoft

“…Europe needs a necessary contact with Russia that through successive stages of diplomacy may evolve from crisis management to agreement on arms control and a new political order. …”
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