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26721
Following Up Patients With Chronic Pain Using a Mobile App With a Support Center: Unicenter Prospective Study
Published 2025-01-01“…The system was developed in collaboration with health care professionals and uses validated scales to capture patients’ clinical data at each stage of treatment (ie, pretreatment phase, trial phase, and implantation phase). …”
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26722
Predictive Value of Initial 18F-FDG PET/CT for Identifying EGFR and KRAS Mutations in Patients with Non-small-cell Lung Cancer
Published 2024-11-01“…Aim: Since the importance of epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene homolog gene (KRAS) mutation status in predicting treatment response in non-small cell lung cancer (NSCLC) patients is well known, we aimed to evaluate whether initial fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography-computed tomography (PET/CT) imaging could non-invasively predict EGFR or KRAS mutation states in this patient group. Methods: This retrospective observational study examined patients with NSCLC who underwent 18F-FDG PET/CT for staging from August 2021 to January 2024. …”
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26723
人胚胎干细胞神经分化的方法探讨
Published 2011-01-01“…【目的】 利用新建系的人胚胎干细胞株SYSU-7,运用胚体形成的方法,探讨不同的分化条件对胚胎干细胞神经分化的影响【方法】 首先检测人胚胎干细胞株SYSU-7的Oct4SSEA4(stage-specific embryonic antigen-4)TRA-1-60和AKP(Alkaline phosphatase)等胚胎干细胞特异性标志物的表达及体内外三胚层分化的能力;之后,应用含20% Knockout Serum Replacement (KSR)的培养液和神经干细胞培养液(neural progenitor medium, NPM)分别诱导细胞形成悬浮的拟胚体(悬浮时间为4 d或7 d),然后将拟胚体贴壁于多聚鸟氨酸(Polyornithine, PO)和纤维粘连蛋白(Fibronectin, FN)包被的培养皿中继续培养4 ~ 10 d在分化的不同时间点利用免疫荧光染色的方法检测胚胎干细胞和神经细胞相关的标志性抗原【结果】 SYSU-7胚胎干细胞表达未分化细胞特异性标志Oct4SSEA4,TRA-1-60,AKP染色呈强阳性,在体内外具有向三胚层分化的潜能;在体外诱导其向神经分化,结果发现KSR培养液比神经干细胞培养液更有利于胚胎干细胞的神经分化,悬浮生长7 d的拟胚体贴壁后出现特征性的玫瑰花环样结构(rosette structure)的时间更早数量更多【结论】 SYSU-7细胞系具有自我更新及多向分化潜能等胚胎干细胞特性本实验为研究人胚胎干细胞的神经分化提供了新的细胞模型和研究思路…”
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26724
Early Vegetation Recovery After the 2008–2009 Explosive Eruption of the Chaitén Volcano, Chile
Published 2024-12-01“…The results suggest that the early stages of succession are shaped by life history traits like dispersion syndrome and regeneration strategy (i.e., vegetative), as was found after other volcanic eruptions. …”
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26725
Study on mechanical properties of sandstone damaged by blasting load under triaxial cyclic loading and unloading
Published 2025-01-01“…The effects of blast-load-induced damage, confining pressure and loading stage on the strength, cohesion, internal friction angle, residual strain and volumetric strain were analyzed. (1) Compared with that of the undamaged specimen at a confining pressure of 0 MPa, the peak stress reductions in the vibration-damaged and blast-damaged specimens were 4.93% and 9.04%, respectively. …”
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26726
Formation of digital literacy components of future teachers in the course of studying the university-wide discipline “Digital Technologies in Education”
Published 2024-12-01“…Experimental work is carried out on the basis of Vyatka State University. The pedagogical experiment involves 111 bachelors in the field of study 44.03.05 “Pedagogical education (with two training profiles)”, profile “Subject training. …”
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26727
University students’ ambition levels and vocational tendencies associated with common culture
Published 2022-06-01“…The Ministry of Education in Jordan should pay more attention to the vocational tendencies among students from earlier stages to direct these tendencies in appropriate ways that provide students with a good academic life leading to decent social, vocational and practical life that gets along with the common Jordanian culture. …”
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26728
Impact of Immune Checkpoint Inhibitors and Local Radical Treatment on Survival Outcomes in Synchronous Oligometastatic NSCLC
Published 2025-03-01“…Methods: Multicenter retrospective study including adequately staged patients, with sOMD NSCLC (maximum five metastases in three organs [European Organization for Research and Treatment of Cancer definition]) between January 1, 2015 and December 31, 2022, treated with a first-line ICI-based versus chemotherapy-only regimen. …”
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26729
The necroptosis-related lncRNA ENSG00000253385.1 promotes the progression of esophageal squamous cell carcinoma by targeting the miR-16-2-3p/VDAC1 axis
Published 2025-01-01“…High lncRNA ENSG00000253385.1 expression, positive lymph node metastasis and clinical stage III were associated with poor overall survival (OS) in patients with ESCC, and were independent risk factors for prognosis of patients with ESCC. …”
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26730
Screening attendance of breast or cervical cancers and its associated factors among 30-49 year old women in Gedeo zone, South Ethiopia: Cross-sectional study.
Published 2025-01-01“…<h4>Method</h4>A community-based cross-sectional study was conducted using a multi-stage cluster sampling technique. Data were collected using pretested, structured questionnaires by trained interviewers. …”
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26731
Sustainability assessment of animal feed production from by-products of Sago palm smallholder industry
Published 2024-07-01“…Furthermore, it was found that techniques in several processing stages or use of liquid waste, cultivation skills, and technology process contributed to sustainable development. …”
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26732
Alterations in the polarization of liver M1/M2 macrophages upon long-term administration of triptorelin in rats
Published 2024-11-01“…The study employed a series of experimental periods, with the introduction of triptorelin and quercetin at varying stages. Materials and methods. The study was conducted on 35 sexually mature male rats. …”
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26733
Influence of magma intrusion and contact distance onthermal effects of low-temperature oxidation processes in coal
Published 2024-12-01“…And the results showed that under different air supply conditions, compared with the original coal, the initial exothermic and thermal equilibrium temperature points in the low-temperature oxidation stage were advanced by 0.2−3.4 ℃ and 1.9−18.2 ℃ for strongly eroded, weakly eroded, and homogeneous high-order coals, the total exothermic capacity was increased by 1.72%−135.75%, and the apparent activation energy was reduced by 1.62%−69.02%, and the closer the metamorphic coal was to the magma intrusion, the more oxidizing and exothermic it was, and the shorter the natural ignition period was. …”
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26734
Pregnancy stressors and postpartum symptoms of depression and anxiety: the moderating role of a cognitive–behavioural therapy (CBT) intervention
Published 2024-02-01“…Background Little is known about the association between stressors (especially positive stressors) during pregnancy and postpartum depression and anxiety.Aims We investigated the association between positive and negative stress events during different stages of pregnancy and postpartum mental health outcomes among low-income pregnant women with symptoms of anxiety in Pakistan and evaluated whether an intervention based on cognitive–behavioural therapy (CBT) had a regulatory effect.Methods Participants were 621 pregnant Pakistani women with mild anxiety. …”
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26735
Marigold: a machine learning-based web app for zebrafish pose tracking
Published 2025-01-01“…We found differences in the number and vigor of swimming bouts between fed and unfed fish at both time points, as well as interactions between developmental stage and feeding regimen. Conclusions In both biological experiments presented here, the use of Marigold facilitated novel behavioral findings. …”
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26736
Altered Topological Properties of Grey Matter Structural Covariance Networks in Complete Thoracic Spinal Cord Injury Patients: A Graph Theoretical Network Analysis
Published 2021-01-01“…SCI patients would experience depressive and/or anxious feelings at the early stage. Their GMV reduction mainly involved psychology-cognition related rather than sensorimotor brain regions. …”
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26737
Adolescent HIV prevent and care framework: A global scoping review protocol- BSGH 006.
Published 2024-01-01“…Among adolescents, HIV/AIDs remains a significant cause of death globally [1-4]. Given the unique stages in human development, adolescents have been shown to fall within a sexually active phase. …”
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26738
Molecular identification of the stem rust resistance genes in the introgression lines of spring bread wheat
Published 2019-05-01“…The analysis of the cultivars’ and lines’ resistance to the Saratov pathogen population in the field, as well as to Omsk, Derbent and Lysogorsk populations at the seedling stage, showed the loss of efficiency of the Sr25 and Sr6Agi genes. …”
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26739
Glioma Image-Level and Slide-Level Gene Predictor (GLISP) for Molecular Diagnosis and Predicting Genetic Events of Adult Diffuse Glioma
Published 2024-12-01“…In conclusion, GLISP is a two-stage AI framework for histology-based prediction of genetic events in adult gliomas, which is helpful in providing essential information for WHO 2021 molecular diagnoses.…”
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26740
Efficacy of myrrh extract against Eimeria labbeana-like experimental infection in Columba livia domestica: in vivo study
Published 2024-12-01“…Furthermore, there was a significant decrease in both the number and size of the developmental stages of E. labbeana-like (i.e. meronts, gamonts, and developing oocysts) in the intestinal tissue among the MyE-treated group. …”
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