Regulation of innate immune response by miRNAs up-regulated in Stevens-Johnson syndrome with severe ocular complications by Mayumi Ueta, Hiromi Nishigaki, Hokoru Yoshioka, Shigeru Kinoshita, Chie Sotozono

“…We analyzed plasma samples from 100 patients with chronic stage SJS/TEN with SOC and 92 healthy controls to examine the expression levels of eight specific miRNAs (let-7a-5p, let-7d-3p, let-7e-5p, miR-146a-5p, miR-130a-3p, miR-151a-3p, miR-151a-5p, miR-27b-3p) using quantitative RT-PCR (RT-qPCR). …”
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Clinical Epidemiology and Phenotypic Characteristics of Hidradenitis Suppurativa Disease in the Central Region of Saudi Arabia: Findings from a Cross-Sectional by Alotaibi H, Madani A, AlFada M, Alluhaybi A, Alsehli T, Almuhaideb Q, Alnasser S, Aldossari A, Barakeh M, AlKanaan R

“…Clinical, epidemiological, and comorbidity data were collected, and the severity of HS was categorized with the Hurley staging system. Statistical analysis was performed with SPSS, with the significance level set to p < 0.05.Results: Of the patients, 54.8% were aged 15– 30 years, 57.04% were female, and 95.56% were Saudi. …”
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Exploring Proso Millet Resilience to Abiotic Stresses: High-Yield Potential in Desert Environments of the Middle East by Srinivasan Samineni, Sridhar Gummadi, Sumitha Thushar, Dil Nawaz Khan, Anestis Gkanogiannis, Luis Augusto Becerra Lopez-Lavalle, Rakesh Kumar Singh

“…These extreme conditions, coinciding with the crop’s critical growth stages, triggered a significant increase in chaffy grain production, substantially reducing overall grain yield. …”
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Effectivity of Musa paradisiaca extract to control Saprolegnia sp. infection on giant gourami larvae by Sri Nuryati, Nadia Aulia, , Rahman

“…ABSTRACT   Larval stage of giant gourami is a critical period due to fungal infection, such as Saprolegnia sp. infection. …”
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The role of partial splenic artery embolization in the management of refractory esophageal variceal bleeding due to portal vein thrombosis by Büşra Tetik Dinçer, Nafiye Urgancı, Aylin Hasanefendioğlu Bayrak, Özlem Durmaz, İlgin Özden

“…Findings were consistent with stage 3 esophageal varices and increased vascularity in the duodenum due to portal vein thrombosis. …”
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Association between triglyceride-glucose index and clinical outcomes among patients with chronic kidney disease: a meta-analysis by Jinli Tuo, Zhong Li, Linshen Xie

“…Secondary outcomes included the coronary artery disease (CAD) mortality, CKD progression, risk of severe coronary artery stenosis (SCAS), major adverse cardiovascular event (MACE), coronary artery calcification (CAC) progression, end-stage renal disease (ESRD), and nonalcoholic fatty liver disease (NAFLD). …”
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Early results of primary total hip arthroplasty performed in young adults at a regional Saudi-Arabian orthopedics center: a prospective observational study by Walid M. Al-Shaer, Ali H. Al-Yami, Mokhtar Ahmed Al-Sayed, Ali Mohammed Al-Zaidan, Emad Ruddah Al-Sufyani, Ahmed A. Khalifa, Raad M. M. Al-Thaqafi, Abdulmohsen H. Al-Hamyani, Mohammed M. Al-Subaie

“…Primary total hip arthroplasty is the option for managing end-stage hip disease, even in younger patients when hip preservation surgeries are invalid. …”
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Exploring caregiver experiences and support needs in end-of-life care for people living with HIV: A scoping review protocol. by Kristina M Kokorelias, Andrew D Eaton, Marina Wasilewski, Tyler Redublo, Luxey Sirisegaram

“…While some of the first public end-of-life care facilities were established due to HIV/AIDS, the current needs of caregivers for people living with end-stage HIV are not well understood. Caregivers provide two-thirds of the care for people living with HIV, yet their specific support needs and experiences are under-researched. …”
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Sacral neuromodulation outcomes in the management of lower urinary tract symptoms in multiple sclerosis patients by Tyler Trump, Po-Ming Chow, Vivian Hua, Omer Anis, Mazen Mansour, Howard B. Goldman

“…More patients underwent stage 1 trial (47/58) than peripheral nerve evaluation (11/58). …”
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The effectiveness of the combined PBL and Tencent Conference online teaching mode in the clinical internship teaching of cardiac surgery. by Xiuwen Chen, Yao Xiao, Yunhui You, Jianxi Zhu, Shiqing Liu, Huiqiong Chen, Hong Zhu

“…Clinical internships in cardiac surgery are an essential stage in the development of medical students. Currently, it is still dominated by the traditional lecture mode. …”
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A Semianalytical Model for Analyzing the Infill Well-Caused Fracture Interference from Shale Gas Reservoirs by Sidong Fang, Yonghui Wu, Cheng Dai, Liqiang Ma, Hua Liu

“…Longer unconnected fractures and more fracturing stages/clusters for the infill well will result in higher production for the infill well, but a negative effect is observed for the parent well. …”
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Ice-proximal sea ice reconstruction in the Powell Basin, Antarctica, since the Last Interglacial by W. W. Khoo, J. Müller, J. Müller, J. Müller, O. Esper, W. Xiao, C. Stepanek, P. Gierz, G. Lohmann, G. Lohmann, G. Lohmann, W. Geibert, J. Hefter, G. Mollenhauer, G. Mollenhauer, G. Mollenhauer

“…Our results also unveil a stronger deglacial amplitude and warming during the Last Interglacial (LIG; Marine Isotope Stage (MIS) 5e) compared to the current one (Holocene). …”
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Characterization of feeding damage by tea mosquito bug, Helopeltis theivora Waterhouse (Hemiptera: Miridae) on Hainan Dayezhong tea cultivar by Qi Yao, Qi Yao, Qi Yao, You-Ze Lin, You-Ze Lin, You-Ze Lin, Shuang Qin, Shuang Qin, Shuang Qin, Zhu-Feng Lin, Zhu-Feng Lin, Zhu-Feng Lin, Xun-Cong Ji, Xun-Cong Ji, Xun-Cong Ji

“…During the feeding peak, adults H. theivora produced more feeding spots than nymphs, with females and 5th-instar nymphs creating the largest feeding areas among all life stages. Field investigations showed that damage caused by H. theivora on the large-leaf HNDYZ tea cultivar was significantly greater than that on the small-leaf Jinxuan tea cultivar. …”
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Reconstruction of Partial Glossectomy Defects in Patients with Squamous Cell Carcinoma of Oral Tongue: A Prospective Clinical Study on the Assessment and Comparison of Intraoperati... by Shubhanshi Kangloo, Nitin Bhola, Anchal Agarwal, Raj Kumar Chakraborty, Priyatam Mishra, Saurabh Pillai

“…In this study, the flap is done in a single stage by tunneling under the mandible. It has a good reach to any aspect of the oral cavity, including the contralateral side, if ipsilateral level Ib nodes are compromised. …”
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Factors associated with malaria in pregnancy among women attending ANC clinics in selected districts of the Ashanti Region, Ghana by Emmanuel Abu Bonsra, Petra Amankwah Osei, Emmanuel Adjei Kyeremeh, Stephen Adama, Akua Grace Sekyi, Elsie Fafa King

“…Methods A cross-sectional study was conducted among 1215 pregnant women selected through multi-stage sampling. Data were collected using structured questionnaires and analysed using descriptive and inferential statistics, including regression analysis. …”
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Serum metabolic profiles in quails: Effects of age, breed, and sex by Qin He, Hanle Shang, Yizhong Huang, Lizhi Li, Zhuomin Wu, Huihui Ran, Jiguo Xu, Xinwei Xiong

“…These findings enhance our understanding of the dynamic changes in quail serum metabolites influenced by various factors and address the knowledge gap regarding serum metabolic changes at different stages in quails.…”
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A numerical model for duricrust formation by water table fluctuations by C. Fenske, C. Fenske, J. Braun, J. Braun, F. Guillocheau, C. Robin

“…Two main hypotheses have been proposed for the formation of duricrusts; i.e. the hydrological or transported model, where the enrichment in the hardening element (iron for ferricretes, silica for silcretes, or calcium carbonates for calcretes) is the product of leaching and precipitation through fluctuations in the water table during contrasted seasonal cycles, and the laterization or in situ model, where the formation of duricrusts is the final compacting stage of laterization.</p> <p>In this article, we present the first numerical geomorphological model for the formation of duricrusts based on the hydrological hypothesis. …”
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Method for predicting the risk of type 2 diabetes mellitus development in persons with visceral obesity and prediabetes by Yulia V. Nelaeva, Alsu A. Nelaeva, Anna E. Yuzhakova, Ivan M. Petrov, Igor F. Sholomov

“…Most of the applied parameters are modifiable, which makes it possible to apply this model at the preventive stage.…”
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Vaginal bleeding during pregnancy: a retrospective cohort study assessing maternal and perinatal outcomes by Maroun Matar, Georges Yared, Christopher Massaad, Kariman Ghazal

“…Although not always a concern, pregnancy-related vaginal bleeding may detrimentally impact maternal and fetal health, and can arise at any stage during the pregnancy, usually linked with preterm labor, miscarriage, placental abnormalities, or implantation bleeding. …”
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Mapping provider and consumer voices using the AACTT framework: a focus group study of advance care planning by Lisa Guccione, Stephanie Best, Sonia Fullerton, Sanchia Aranda, Jill J. Francis

“…To effectively address these complexities, it is crucial to first identify the specific roles and actions required at each stage of the intervention. This approach enables a thorough examination of what is working well and what needs to be optimised. …”
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