hERGAT: predicting hERG blockers using graph attention mechanism through atom- and molecule-level interaction analyses by Dohyeon Lee, Sunyong Yoo

“…Our model achieved an area under the receiver operating characteristic of 0.907 and an area under the precision-recall of 0.904, demonstrating its effectiveness in modeling hERG activity and offering a reliable framework for optimizing drug safety in early development stages. Scientific contribution: hERGAT is a deep learning model for predicting hERG blockers by combining GAT and GRU, enabling it to capture complex interactions at atomic and molecular levels. …”
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Unfolding insights about resilience and its coping strategies by medical academics and healthcare professionals at their workplaces: a thematic qualitative analysis by Salman Yousuf Guraya, Jacqueline Maria Dias, Mohamed Ahmed Eladl, Ayah Mohammad Rajai Rustom, Fatima Audi Saleem Alalawi, Majid Hassan Saleh Alhammadi, Yusra Ahmed Mohammed Ahmed, Amna Ali Omran Taryam Al Shamsi, Sarah Juman Bilalaga, Alfred Nicholson, Hani Malik, Shaista Salman Guraya

“…Lastly, we adopted the Braun and Clarke 6-stage thematic model for qualitative data analysis. …”
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Revealing the biological features of the axolotl pancreas as a new research model by Hui Ma, Hui Ma, Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei, Jifeng Fei, Jifeng Fei

“…RNA sequencing was performed to profile global gene expression during larva and adult stages. And differential gene expression analysis was used to characterize the conserved and unique gene patterns in the axolotl pancreas. …”
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Permeability Characteristics of Combined Coal with Different Water Contents by Hongyu Pan, Yao Zhang, Lei Zhang, Yan Cao, Yuhang Chu, Shihua Yang

“…Hydraulic fracturing changes the stress state of the coal body, and the residual water within the coal body after fracturing affects its permeability characteristics. …”
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« Une femme en Côte d’Ivoire, une femme au Burkina Faso » by François Ruf

“…These ‘women who stay back or return’ not only reflect history, the stakes and issues of the Ivorian – or rather ‘Ivorian/West African’ – plantation economy, but also themselves write a new page in it.…”
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Potential profiling of social alienation in older female patients with stress urinary incontinence by Yakun Li, Hongxia Wang

“…The results of multifactorial logistic regression analysis showed that occupational status, marital status, whether living alone, place of residence, BMI, whether other chronic diseases, level of narrative disorders, and level of family care were the influencing factors of social alienation in older adult female patients with stress urinary incontinence (P < 0.05).ConclusionThe social alienation of older adult female patients with stress urinary incontinence is characterized by a significant number of categories, and healthcare professionals can identify the characteristics and influencing factors of each category at an early stage, which can provide a basis for the development of targeted clinical interventions to help patients reduce the level of social alienation.…”
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Le chemin des « mauvaises filles » by Véronique Blanchard, Hélène Duffuler-Vialle

“…The young innocent girl who, whatever her way, has necessarily deviated in some way, earns her freedom or gets trapped depending on the throw of the dice and the choices made by the visitors/players, who have several options at different stages of the play. The second part of the exhibition takes the public to a locked room where big photographs and copies of imprisoned girls’ words show the effect of confinement throughout the ages.The aim or the exhibition is tolerance and humanism. …”
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20 ans d’Observatoire photographique des paysages dans le Parc naturel régional des Vosges du Nord by Romy Baghdadi

“…It needs to pro-actively encourage discussion, provide answers and, above all, inspire initiatives. At this stage in its existence, its aim should be to render the constant changes as well as sudden transformations and successive territorial layers of the landscape visible and understandable but, above all, it should reveal the emergence of a new local landscape culture born of a collective perspective, while steering clear of any systematic consensual touristic imagery. …”
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Efficacy of root canal treatment for autotransplanted third molars: a 6-Year cohort study of 167 teeth in southern China by Bangfeng Han, Liu Liu, Zhishen Jiang, Li Ye, Yubin Cao, Jian Pan

“…Patients underwent autogenous tooth transplantation to replace non-retainable molars with upper or lower third molars with Moorrees tooth development stage ≥5. All surgical procedures were performed by an experienced surgeon. …”
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Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana by Debasish Banerjee, Jacob Plange-Rhule, Nihil Chitalia, Kwabena Kumi, Frank B. Micah, Francesco P. Cappuccio, John B. Eastwood

“…Hypertension, particularly pulse pressure [PP] is a major risk factor for end-stage renal disease. However, the effect of individual components of hypertension namely PP, systolic [SBP] and diastolic blood pressure [DBP] on kidney function, in the general African population is unknown. …”
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Requiem – Alàgbà, Dr., Prince, Mosọbalájé Ajíbádé Àkàndé Adébáyọ̀ Fálétí, OON, DLitt., FNAL, JP, a.k.a ‘Pa Fálétí’ to Some; ‘Bàbá Fálétí’ to all and Sundry.... by Pamela J. Olubunmi Smith

“…Olubunmi Smith Thanks to the immense, providential endowment trumpeted on the airwaves, and flashed on screen, and showcased on makeshift stages from hamlet, to village, to town squares and city halls, and planted in almost every household so the gen-X and gen-Y Yorùbá can, in varying degrees, claim knowledge of and familiarity with Bàbá Fálétí, the man, the artist, the actor, the prodigious poet, indeed, the half-sung, consummate bard, the cultural icon, beloved son of Yorùbáland. …”
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Analogs of Precambrian microbial communities formed de novo in Caucasian mineral water aquifers by Daria G. Zavarzina, Alexey A. Maslov, Alexander Y. Merkel, Nataliya A. Kharitonova, Alexandra A. Klyukina, Ekaterina I. Baranovskaya, Elena A. Baydariko, Evgeniy G. Potapov, Kseniya S. Zayulina, Andrey Y. Bychkov, Nikolay A. Chernyh, Elizaveta A. Bonch-Osmolovskaya, Sergey N. Gavrilov

“…The characterization of the YMWB microbial communities reveals a contemporary model environment of the early stages of Earth’s development and thus contributes to the understanding of the evolutionary traits in microbial populations that may have played a critical role in the formation of the modern biosphere.IMPORTANCEContinental subsurface environments are estimated to harbor up to one-fifth of the planet’s total biomass, representing the most stable and slowly evolving part of the biosphere. …”
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Glycated hemoglobin and microalbuminuria in patients with type 2 diabetes mellitus by Afrim Zeqiraj, Dafina Zeqiraj, Teuta MullaGoga, Fidel Krasniqi, Agim Shabani, Sanije Berisha, Agim Berisha, Blerim Morina, Florjana Zogaj

“…Microalbuminuria is the earliest stage of progressive kidney damage, the simplest and most reliable predictor for assessing the probability of overt nephropathy in diabetes. …”
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How learning to read Braille in visual and tactile domains reorganizes the sighted brain by Maciej Gaca, Alicja M. Olszewska, Dawid Droździel, Agnieszka Kulesza, Małgorzata Paplińska, Bartosz Kossowski, Katarzyna Jednoróg, Jacek Matuszewski, Aleksandra M. Herman, Artur Marchewka

“…Since neuroplasticity can occur within days, understanding neural reorganization during early learning stages is critical. Moreover, such activation was not tested in visual and tactile domains using comparable tasks. …”
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Effect of Triple Acupuncture Therapy Combined with Rehabilitation Training on CGRP Content in Peripheral Blood, Motor Function and Activity of Daily Living of Spinal Cord Injury Pa... by Yinjie CUI, Qian WANG, Yue JIANG, Anren ZHANG

“…The CGRP content in peripheral blood may be a potential protein for functional recovery of SCI patients in the early stage.…”
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Anaesthetic efficacy of intraligamentary injection compared to incisive nerve block using 3% mepivacaine hydrochloride: a randomized clinical trial by Suzan Salem, Islam Saad, Ramy Elmoazen, Ghada Amin Khalifa

“…The effectiveness of the two local anaesthesia techniques, intraligamentary injection technique (ILI) and incisive nerve block (INB), were compared using Modified Dental Anxiety Scale for Dental Extraction Procedure (MDAS-DEP) and visual analogue scale (VAS) during the injection and extraction stages of the procedure. Results A total of 100 participants (42 females, 58 males) with a mean age of 50.97 ± 11.59 years took part in the study. …”
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Virulence factor discovery identifies associations between the Fic gene family and Fap2+ fusobacteria in colorectal cancer microbiomes by Geicho Nakatsu, Duhyun Ko, Monia Michaud, Eric A. Franzosa, Xochitl C. Morgan, Curtis Huttenhower, Wendy S. Garrett

“…Using a global data set of CRC shotgun metagenomes, we show that fusobacterial Fic and Fap2 genes frequently co-occur in the fecal microbiomes of individuals with late-stage CRC. We further characterize specific Fic gene families harbored by Fap2+ Fusobacterium animalis genomes and detect recombination events and elements of horizontal gene transfer via synteny analysis of Fic gene loci. …”
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Delayed Antiretroviral Therapy (ART) Initiation among Hospitalized Adults in a Resource-Limited Settings: A Challenge to the Global Target of ART for 90% of HIV-Infected Individual... by Prossie Merab Ingabire, Fred Semitala, Moses R. Kamya, Damalie Nakanjako

“…Sociodemographic characteristics, WHO clinical stage, CD4 count, cART initiation status, and reasons for delayed cART initiation were extracted and analyzed. …”
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Characteristics of virulence of Puccinia triticina populations and the potential of the Lr24, Lr25, LrSp genes for spring common wheat breeding in the Southern Ural by V. A. Tyunin, E. R. Shreyder, E. I. Gultyaeva, E. L. Shaydayuk

“…The results on the effectiveness of Lr-genes at the seedling stage correlated with estimates for Thatcher Lr-lines, breeding materials and varieties with known Lr-genes grown at the field on the breeding nursery of the Сhelyabinsk Research Institute of Agriculture. …”
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Impaired hemodynamic forces assessed by routine CMR and its determinants in different duration T2DM patients with normal LV function and myocardial strain by Guozhu Shao, Guozhu Shao, Guozhu Shao, Yukun Cao, Yukun Cao, Yukun Cao, Yue Cui, Yue Cui, Yue Cui, Hongyan Li, Heshui Shi, Heshui Shi, Heshui Shi

“…T2DM patients were divided into three groups according to the course of disease: early, middle and later stage (time <5 years, 5 ≤ time <10 years, time ≥10 years, respectively). …”
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