Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production by Yan Tian, Chenxia Zhou, Qun Yan, Ziyi Li, Da Chen, Bo Feng, Jun Song

“…Background Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease. Sodium-glucose cotransporter protein 2 inhibitors (SGLT2i) are antihyperglycemic agents that provide additional renal-protective effects in patients with DKD, independent of their glucose-lowering effects. …”
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NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells by Jianfen Shen, Shuo Zhang, Shuo Zhang, Yan Song, Yan Song, Leiming Yang, Leiming Yang, Qi Huang, Qi Huang, Pengyu Wang, Pengyu Wang, Youzhi Zhang, Youzhi Zhang

“…Moreover, THSG could induce cell cycle arrest in G2/M stage and reduce ferroptosis-related protein expression (xCT and GPx4). …”
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DIVERSITY OF THE PUMPKIN COLLECTION AND ITS HEREDITARY POTENTIAL. RESULTS AND PROSPECTS OF BREEDING PRACTICE by A. G. Elatskova

“…New bushy lines of C. maxima and C. moschata selected from cultivar and hybrid populations are now tested in an elite test nursery in order to submit the best of them to the State Variety Trials.…”
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Polyphenolic compounds in Sauvignon Blanc - from grapes to wine by Davin Williams, Anscha Zietsman, Jeanne Brand, Hans Eyeghe-Bickong, Melané Vivier

“…In berries, flavonols showed the largest increase due to sun exposure (HL treatment) but were absent from the juice samples at all juice processing stages. They were however detected in the juice sediment, together with high concentrations of organic acids and sugars. …”
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The XIAP inhibitor AZD5582 improves the treatment effect of microwave ablation on hepatocellular carcinoma by Wenhui Wang, Fuyuan Wu, Zhe Wu, Mengfan Zhang, Qiang Lu

“…Background and purposeMicrowave ablation (MWA) is one of the first-line therapy recommended for early-stage hepatocellular carcinoma (HCC). However, the residual tumor, resulting from insufficient ablation, led to recurrence and metastasis of liver cancer. …”
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Evaluation of the effectiveness of a peptide-cytokine agent in the complex therapy of recurrent candidal vulvovaginitis by Elena A. Rosyuk

“…All patients underwent all stages of diagnosis and treatment. Group 1 (n=30) received standard of care with antimycotics + Superlymph 10 units twice a day vaginally for 10 days. …”
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Rola usług Spa & Wellness w kreowaniu pozytywnych doświadczeń konsumentów na przykładzie produktów hotelowych by Aleksandra Grobelna, Barbara Marciszewska

“…Obecnie Spa & Wellness staje się dynamicznie rozwijającym komponentem oferty hotelu. …”
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Inheritance of scald resistance in four barley landraces by G. S. Konovalova, E. E. Radchenko

“…According to the hybridological analysis data, k-27205 has one dominant gene of scald resistance; k-16233, k-27768 and k-22299 are protected by two dominant effective resistance genes, all of which manifest themselves at all the stages of plant ontogenesis.…”
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Transcriptomic and genetic analysis reveals a Zn2Cys6 transcription factor specifically required for conidiation in submerged cultures of Thermothelomyces thermophilus by Florian Drescher, Yang Li, Jose Manuel Villalobos-Escobedo, Stefan Haefner, Lori B. Huberman, N. Louise Glass

“…The identification of stage-specific developmental regulation of asexual spore production and comparative analyses of conidiation in filamentous ascomycete species have the potential to further manipulate these species for industrial advantage.…”
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Construction and Application of Enterprise Internal Audit Data Analysis Model Based on Decision Tree Algorithm by Yuna Si

“…The internal audit process in this paper refers to the internal audit process under the risk-oriented model that is widely used at this stage. The optimization research on the internal audit process in this paper is mainly aimed at the internal audit process of general enterprises with a certain level of informatization, at a large scale, and certain foundation and requirements for the analysis and use of data. …”
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Mathematical modelling-based blockchain with attention deep learning model for cybersecurity in IoT-consumer electronics by Hayam Alamro, Mohammed Maray, Jawhara Aljabri, Saad Alahmari, Monir Abdullah, Jehad Saad Alqurni, Faiz Abdullah Alotaibi, Abdelmoneim Ali Mohamed

“…The MGOADL-CS method aims to improve cybersecurity using BC technology in the drone's environment by detecting attacks using optimal DL models. In the initial stage, the MGOADL-CS technique uses a linear scaling normalization (LSN) approach to normalize the input data. …”
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Clinical Features and Prognosis Analysis of Hormone Receptor-Positive, HER2-Negative Breast Cancer with Differential Expression Levels of Estrogen and Progesterone Receptors: A 10-... by Jin Liu, Mingyu Gan, Zijing Lin, Qin Deng, Juan Deng, Bin Zeng, Yanling Shi, Jia Ming

“…L group patients had significantly more stage N2 axillary lymph nodes than H group patients (31.8% vs. 9.2%, P = 0.007). …”
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A cross-sectional study exploring the predictors of herpes zoster vaccination for people aged over 50 years old in Chaoyang district, Beijing by Jiao Zhang, Shuo Zhang, Bin Jia, Yunhua Bai, Zhen Li, Fang Liu, Yingxue Hu, Xiaojing Guo, Jianxin Ma, Shuming Li, Qian Shi

“…The coverage of herpes zoster vaccination is extremely low in China, and there is a notable lack of research investigating the barriers to promoting the herpes zoster vaccine in China.ObjectivesThis study aims to survey the status of herpes zoster (HZ) vaccination and its associated factors among individuals aged 50 years and older, it also seeks to identify the barriers to vaccination and dissemination, thereby providing a scientific foundation for enhancing the vaccination rate of herpes zoster.MethodsFrom March to August 2023, a questionnaire survey was conducted using a multi-stage sampling method on permanent residents aged 50 years and older in Chaoyang district of Beijing. …”
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Socioeconomic and behavioural factors that contribute to the co-occurrence of risk factors for noncommunicable diseases by Naftal Sakaria, Nelago Indongo

“…NCDs share key modifiable behavioral risk factors like unhealthy diet and lack of physical activity that are typically established during adolescence or young adulthood and will set the stage for NCDs development later in life. Therefore, this paper aimed to explore factors contributing to the co-occurrence of risk factors for NCDs among persons aged 30 years and above in selected urban areas of Namibia. …”
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Effect of Isoniazid Preventive Therapy on the Incidence of Tuberculosis among Seropositive Children Attending HIV/AIDS Care in Two General Hospitals, Northwest Ethiopia, 2021 by Fassikaw Kebede, Birhanu Kebede, Tsehay Kebede, Melaku Agmasu

“…Missed IPT (AHR = 7.45, 95% CI: 2.96, 18.74, P<0.001), missed cotrimoxazole preventive therapy (CPT) (AHR = 2.4, 95% CI: 1.84–4.74, P<0.022), age ≥ 11 years (AHR = 4.2, 95% CI: 1.04–7.03, P<0.048), MUAC ≤ 11.5 cm (AHR = 4.36, 95% CI: 1.97–9.97, P<0.001), WHO stages III and IV (AHR = 2.04, 95% CI: 1.12–3.74, P<0.022), and CD4 count ≤100 cells/μl (AHR = 3.96, 95% CI: 1.52–10.34, P<0.005) were significantly associated with TB incidence. …”
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Dermatologic Adverse Events Following Afatinib in a Woman with Non-Small-Cell Lung Cancer: A Case Report by Tsaqilah L, Putri AD, Avriyanti E

“…We report a case of 31-year-old woman diagnosed with stage IV-NSCLC and treated with afatinib since nine months prior to consult who presented with acneiform rash on the face, trunk, both arms and legs; pruritic pustules and waxy scales on the scalp; xerosis and pruritus of the skin; paronychia on both toes; hair changes on the scalp, eyebrows, eyelashes, and hypertrichosis of the face. …”
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Experiences and perceptions of respectful maternity care among mothers during childbirth in health facilities of Eastern province of Rwanda: An appreciative inquiry. by Alice Muhayimana, Irene Josephine Kearns, Darius Gishoma, Olive Tengera, Thierry Claudien Uhawenimana

“…Data collection involved in-depth interviews (IDIs) following the first four stages of the Appreciative Inquiry (AI) 5D cycle. …”
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CompSafeNano project: NanoInformatics approaches for safe-by-design nanomaterials by Dimitrios Zouraris, Angelos Mavrogiorgis, Andreas Tsoumanis, Laura Aliisa Saarimäki, Giusy del Giudice, Antonio Federico, Angela Serra, Dario Greco, Ian Rouse, Julia Subbotina, Vladimir Lobaskin, Karolina Jagiello, Krzesimir Ciura, Beata Judzinska, Alicja Mikolajczyk, Anita Sosnowska, Tomasz Puzyn, Mary Gulumian, Victor Wepener, Diego S.T. Martinez, Romana Petry, Naouale El Yamani, Elise Rundén-Pran, Sivakumar Murugadoss, Sergey Shaposhnikov, Vasileios Minadakis, Periklis Tsiros, Harry Sarimveis, Eleonora Marta Longhin, Tanima SenGupta, Ann-Karin Hardie Olsen, Viera Skakalova, Peter Hutar, Maria Dusinska, Anastasios G. Papadiamantis, L. Cristiana Gheorghe, Katie Reilly, Emilie Brun, Sami Ullah, Sebastien Cambier, Tommaso Serchi, Kaido Tämm, Candida Lorusso, Francesco Dondero, Evangelos Melagrakis, Muhammad Moazam Fraz, Georgia Melagraki, Iseult Lynch, Antreas Afantitis

“…The CompSafeNano project, a Research and Innovation Staff Exchange (RISE) project funded under the European Union's Horizon 2020 program, aims to advance the safety and innovation potential of nanomaterials (NMs) by integrating cutting-edge nanoinformatics, computational modelling, and predictive toxicology to enable design of safer NMs at the earliest stage of materials development. The project leverages Safe-by-Design (SbD) principles to ensure the development of inherently safer NMs, enhancing both regulatory compliance and international collaboration. …”
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Prevalence, Clinical Presentation, and Outcome of Tuberculosis in Patients with Chronic Kidney Disease at a Tertiary Care Hospital in Nepal by Ravi R. Pradhan, Mahesh Raj Sigdel

“…We included patients older than 16 years with the diagnosis of CKD stage 3, 4, 5, and 5D (CKD 5 on maintenance dialysis); renal transplant recipients and patients living with HIV/AIDS were excluded. …”
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Chronic Liver Disease in Ethiopia with a Particular Focus on the Etiological Spectrums: A Systematic Review and Meta-Analysis of Observational Studies by Behailu Terefe Tesfaye, Temesgen Mulugeta Feyissa, Azmeraw Bekele Workneh, Esayas Kebede Gudina, Mengist Awoke Yizengaw

“…The keywords “hepatitis, chronic” [Mesh], “end-Stage Liver Disease” [Mesh], “chronic liver disease”, “liver cirrhosis” [Mesh], and “Ethiopia” were used for the searches. …”
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