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26241
Epithelial stem cells from human small bronchi offer a potential for therapy of idiopathic pulmonary fibrosisResearch in context
Published 2025-02-01“…Methods: Airway trees spanning the proximal–distal axis were harvested from control lungs and explanted lungs with end-stage IPF undergoing transplant. Qualified basal cells (BCs, p63/Krt5/ITGA6/NGFR) were expanded, and their cellular functions, feasibility, safety and efficacy for transplantation therapy in IPF were validated with experiments in vitro and mouse model. …”
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26242
An underground coal mine multi-target detection algorithm
Published 2024-12-01“…To address these issues, based on the single-stage target detection algorithm YOLOv8n, this study proposed an underground coal mine multi-target detection algorithm based on feature extraction by dynamic snake convolution (FEDSC)-feature fusion by bi-directional feature pyramid network and semantic and detail fusion (FFBD). …”
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26243
Clinicopathological Factors Influencing Lymph Node Yield in Colorectal Cancer: A Retrospective Study
Published 2019-01-01“…Many colorectal resections do not meet the minimum of 12 lymph nodes (LNs) recommended by the American Joint Committee on Cancer for accurate staging of colorectal cancer. The aim of this study was to investigate factors affecting the number of the adequate nodal yield in colorectal specimens subject to routine pathological assessment. …”
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26244
Prognostic and clinicopathological role of soluble programmed cell death ligand-1 in patients with diffuse large B-cell lymphoma: a meta-analysis
Published 2025-01-01“…Moreover, based on the pooled data, higher sPD-L1 was significantly related to the Eastern Cooperative Oncology Group Performance Status Scale (ECOG PS) ≥2 (OR=4.10, 95%CI=1.82-9.24, p=0.001), clinical stage III-IV (OR = 3.30, 95%CI = 1.48–7.39, p = 0.004), elevated lactate dehydrogenase (LDH) levels (OR = 2.14, 95%CI = 1.07–4.30, p = 0.032), and the International Prognostic Index (IPI) score 3–5 (OR = 3.83, 95%CI = 1.91–7.68, p < 0.001) in DLBCL.ConclusionAccording to our findings, a higher sPD-L1 level was a significant predictor of poor OS and PFS in patients with DLBCL. …”
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26245
Sensitive windows for within- and trans-generational plasticity of anti-predator defences
Published 2023-08-01“…However, the sensitive window also persisted until late developmental stages for some defences, providing evidence that the early-life is not the only sensitive window as empirical and theoretical studies often state. …”
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26246
Optimizing Healthcare Expenditure for Spinal Cord Stimulation in Italy: The Value of Battery Longevity Improvement and a Direct-to-Implant Approach
Published 2024-05-01“…It is performed in 2 stages (a trialing phase followed by permanent device implantation) and necessitates 2 hospitalizations, which may increase infection risk. …”
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26247
Efficacy analysis of drug-eluting beads transcatheter arterial chemoembolization combining systemic chemotherapy and immune checkpoint inhibitors in unresectable intrahepatic chola...
Published 2025-01-01“…After a propensity score matching analysis to control for the consistency of patient age, sex, tumor size, tumor number, Child grade, ECOG score, and tumor stage. Propensity score matching analysis created 71 pairs of patients in 2 groups. …”
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26248
Study protocol for a Prospective Observational study of Safety Threats and Adverse events in Trauma (PrO-STAT): a pilot study at a level-1 trauma centre in Canada
Published 2025-01-01“…Despite the establishment of specialised trauma centres, there remains considerable variability in trauma-care practices and outcomes, particularly in the initial phase of trauma resuscitation in the trauma bay. This stage is prone to preventable errors leading to adverse events (AEs) that can impact patient outcomes. …”
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26249
Combined negative pressure wound therapy with new wound dressings to repair a ruptured giant omphalocele in a neonate: a case report and literature review
Published 2025-01-01“…The main treatments include one-time repair and staged surgery using synthetic and biologic mesh, or silos. …”
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26250
Heterogeneous foraging swarms can be better
Published 2025-01-01“…Treating every collision as a stage in the repeating game, the overhead is bounded by the total EI of all robots. …”
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26251
Barriers Impeding Postgraduate Training Completion and Dissertation Submission and Defense
Published 2019-09-01“…The article analyzes the barriers that arise at the stages of training in postgraduate school and preparing for thesis defense. …”
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26252
Analysis of general plans of the USSR universities in 1970–1980
Published 2023-11-01“…Most of the general plans of existing Russian universities were approved during the Soviet period. At the present stage of the development of educational infrastructure in Russia, an important task is to determine the possibilities for further expansion and improvement of higher educational institutions in terms of their architectural and planning features and the potential laid in the master plans of higher educational institutions by architects of the past.Materials and methods. …”
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26253
Current methodologies of creating material passports: A systematic literature review
Published 2025-07-01“…Guided by Kitchenham’s [37] guidelines and enhanced by modified PRISMA processes, the SLR was conducted in three stages: Planning, Review Execution, and Reporting. …”
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26254
Osmanlı Öncesi İpekçiliğe Dair İzler ve Osmanlı Dönemi Edirne İpekçiliği
Published 2021-12-01“…Just as sericulture has been a mysterious and secretive area of activity for millennia, it is also a culture that has been inherited throughout generations and that has carried very rigorous labor and technical accumulation within itself in all its stages. The role that Turkish states and communities played in the way that the silk culture has been carried beyond its Asian borders, where it was centered, and has been developed further, as reflected in research, is ambiguous and vague. …”
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26255
Systematic review of the application of the Kidney Failure Risk Equation and Oxford classification in estimating prognosis in IgA Nephropathy
Published 2025-01-01“…Eligible outcomes were reduction of estimated glomerular filtration rate (eGFR) or end-stage renal disease (ESRD), and prognostic tools were required to assess the accuracy of these formulae by discrimination and/or calibration. …”
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26256
Effect of Brewers’ Spent Grain Addition to a Fermented Form on Dough Rheological Properties from Different Triticale Flour Cultivars
Published 2024-12-01“…According to the data obtained, BSF addition decreased water absorption values; torques values corresponding to stages 1–5 of the Mixolab curve; and dynamic rheological elastic, viscous, and complex modules. …”
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26257
Procedural sedative effect of remimazolam in ICU patients on invasive mechanical ventilation: a randomised, prospective study
Published 2025-01-01“…Conclusion Remimazolam is a novel benzodiazepine that has demonstrated promising applications in general anaesthesia and procedural sedation; however, its use in ICU sedation is still in the early stages of research. Current evidence suggests that remimazolam is a safe sedative that is particularly well suited for patients with haemodynamic instability. …”
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26258
Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit
Published 2025-01-01“…We obtained cognitive baseline data and follow up scores for the Mini-Mental State Examination (MMSE), the CDR scale, and the neuropsychological battery used in our center (NBACE). …”
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26259
Proportional-Switch Adjustment Process-Based Day-by-Day Evolution Model for Mixed Traffic Flow in an Autonomous Driving Environment
Published 2025-01-01“…A sensitivity analysis of traveler responses in the daily evolution model reveals that, as the sensitivity of CAVs to impedance changes increases, the fluctuations in mixed traffic flow during the early stages of evolution become more pronounced, and the time required to reach a mixed-equilibrium state decreases. …”
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26260
Levosimendan and Global Longitudinal Strain Assessment in Sepsis (GLASSES 1): a study protocol for an observational study
Published 2020-09-01“…Introduction Cardiogenic shock is a condition of low cardiac output that represents the end stage of a progressive deterioration of cardiac function. …”
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