3-MA attenuates collagen-induced arthritis in vivo via anti-inflammatory effect and autophagy inhibition by Chong Feng, Zi-rou Wang, Chen-yu Li, Xiang-yu Zhang, Xin-xing Wang

“…A recent study showed autophagy modulation may be a novel strategy in the treatment of RA. 3-Methylademine (3-MA), is the most widely used autophagy inhibitor, which blocks autophagy at the initiation and maturation stages. The aim of this study is to evaluate the effect of 3-MA in collagen-induced-arthritis (CIA) mice and further elucidate how 3-MA attenuated inflammation, and cartilage/bone damage in arthritis. …”
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Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma by Yunping Lu, Yajun Shen, Lingyu Li, Min Zhang, Min Wang, Lihua Ge, Jing Yang, Xiaofei Tang

“…By the analysis of Bioinformation Databases, there was a significant interaction of FOXO4 down expression to clinical tumor stages and pathological grades in the patients with HNSCC. …”
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Diagnosis-Based Hybridization of Multimedical Tests and Sociodemographic Characteristics of Autism Spectrum Disorder Using Artificial Intelligence and Machine Learning Techniques:... by M. E. Alqaysi, A. S. Albahri, Rula A. Hamid

“…It is challenging to discover autism in the early stages of life, which prompted researchers to intensify efforts to reach the best solutions to treat this challenge by introducing artificial intelligence (AI) techniques and machine learning (ML) algorithms, which played an essential role in greatly assisting the medical and healthcare staff and trying to obtain the highest predictive results for autism spectrum disorder. …”
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CSGD-YOLO: A Corn Seed Germination Status Detection Model Based on YOLOv8n by Wenbin Sun, Meihan Xu, Kang Xu, Dongquan Chen, Jianhua Wang, Ranbing Yang, Quanquan Chen, Songmei Yang

“…This study further proposes a new module named C2f-UIB-iAFF based on the faster implementation of cross-stage partial bottleneck with two convolutions (C2f), universal inverted bottleneck (UIB), and iterative attention feature fusion (iAFF) to replace the original C2f in YOLOv8, streamlining model complexity and augmenting the feature fusion prowess of the residual structure. …”
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A novel sustainable biocide against the fruit fly Drosophila suzukii made from orange peels by Giovanni Davide Barone, Manfred Hartbauer

“…The ability of the female flies to lay eggs within fruits of varying maturity stages, combined with the accelerated offspring development within warmer climates, results in rapid population growth. …”
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Kynurenines and aerobic exercise capacity in chronic kidney disease: A cross-sectional and longitudinal study. by Helena Wallin, Eva Jansson, Sophie Erhardt, Carin Wallquist, Britta Hylander, Stefan H Jacobson, Kenneth Caidahl, Anette Rickenlund, Maria J Eriksson

“…<h4>Methods</h4>We included 102 patients with non-dialysis CKD stages 2-5 (CKD 2-3, n = 54; CKD 4-5, n = 48) and 54 healthy controls, age- and sex-matched with the CKD 2-3 group. …”
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Satisfied with the worst health outcomes or unsatisfied with the best: explaining the divergence between good patient-reported outcomes and low satisfaction and vice versa among kn... by Lukas Schöner, Viktoria Steinbeck, Reinhard Busse, Carlos J. Marques

“…Abstract Objectives Total knee arthroplasty (TKA) is an effective treatment for patients with end-stage knee osteoarthritis but some patients exhibit a discrepancy between patient-reported outcomes (PROs) and patient satisfaction (PS). …”
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Radiation knowledge and anxiety levels among residents proximity to the world’s first AP1000 nuclear power unit by Jiadi Guo, Zhiqiang Xuan, Cuiping Lei, Taotao Zheng, Zhongjun Lai, Xiaoji Hao, Shunfei Yu, Yiyao Cao

“…ObjectiveAssess the level of radiation-related knowledge (RRK) and nuclear energy-related knowledge (NERK) among residents near the Sanmen Nuclear Power Plant, the first project adopted the Advanced Passive Pressurized Water Reactor (AP1000) technology.MethodsIn this study, respondents were selected using stratified multi-stage random sampling for residents aged 18 years and above living within 30 kilometers of the Sanmen Nuclear Power Station. …”
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Using the Theory of Planned Behavior to Explain Expecting Couples Birth Preparedness Intentions in a Rural Setting: A Cross-Sectional Study from Rukwa, Southern Tanzania by Fabiola V. Moshi, Stephen M. Kibusi, Flora Fabian

“…A community based cross-sectional study targeting pregnant women and their partners was performed from June until October 2017. A three-stage probability sampling technique was employed to obtain a sample of 546 couples A structured questionnaire based upon the Theory of Planned Behavior was used. …”
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Applying the language acquisition model to the solution small language processing tasks by Dz. I. Kachkou

“…The relevance of this task is due to the following considerations: the need to eliminate the information inequality between speakers of different languages; the need for new tools for the study of poorly understood languages, as well as innovative approaches to language modeling in the low-resource context; the problem of supporting and developing small languages.There are three main objectives in solving the problem of small natural language processing at the stage of describing the problem situation: to justify the problem of modeling language in the context of resource scarcity as a special task in the field of natural languages processing, to review the literature on the relevant topic, to develop the concept of language acquisition model with a relatively small number of available resources. …”
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MANIPULATIVE TACTICS IMPLEMENTATION IN POLITICAL DISCOURSE by Tatyana P. Paliy, Inna N. Poteryakhina

“…The empirical material was interviews and individual statements of leading Russian and Western politicians, as well as the works of domestic and foreign political scientists and journalists presented in modern media. At certain stages of the study, in the course of the work, such research methods as discourse analysis, linguistic description, contextual and semantic analysis were used. …”
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Translation, cross-cultural adaptation and psychometric evaluation of the Serbian Ankylosing Spondylitis Quality of Life (ASQoL) Questionnaire (refers to r-axSpA) and its relations... by Mirjana Zlatkovic-Svenda, Ana Djokic, Andjela Perunicic, Marija Zdravkovic, Slavica Pavlov Dolijanovic, Jeanette Thorpe, Dejan Dudok, Jelena Milicevic, Dejana Petrovic, Goran Radunovic

“…Abstract Objectives To translate, cross-culturally adapt and validate the Serbian Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire, e.g. according to the new nomenclature Radiographic-Axial Spondyloarthritis (r-axSpA), and to relate it to disease activity and functional status domains. Methods Four stages were accomplished: (1) Bilingual and lay panel for translation and cross-cultural adaptation (2) Cognitive debriefing interviews (assessing the language and cultural equivalence of the concepts used in the Serbian ASQoL translation) for face and content validity (3) Psychometric evaluation: (a) convergent validity by NHP as a comparator scale and (b) known group validity by correlations with disease activity and overall health status and reliability (internal consistency and test-retest reliability) (4) Independent regression analyses for relations between ASQoL and ASDAS, BASDAI, BASFI, Schober’s test, respiratory index and SPARCC were used. …”
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Methodology for the organisation of professional training of senior citizens: general concept by T. M. Rezer

“…The obtained results allowed the author to conclude that at present stage of the Russian state and Russian society development, there is a need for scientific interdisciplinary knowledge, which substantiates the principles and didactic support of professional training of senior citizens in order to continue their active labour activity and to propose the concept for building the model for the organisation of such training. …”
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2D Fast Vessel Visualization Using a Vessel Wall Mask Guiding Fine Vessel Detection by Sotirios Raptis, Dimitris Koutsouris

“…We advocate that these changes can be addressed as subsequent stages of the same vessel detection procedure. We first carry out an initial estimate of the basic vessel-wall's network, define the main wall-body, and then try to approach the ridges and branches of the vasculature's using fine detection. …”
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Integrated analysis of the transcriptome and hormone metabolome elucidates the regulatory mechanisms governing walnut bud germination by Kai Zhao, Xiaofan Wu, Bo Liang, Shuang Gao, Jieyan Yang, Yan Bai, Yaru Wang, Xin Tian, Fang Wang, Xiuqing Yang

“…By assessing hormone levels and gene expression at different developmental stages, we pinpointed potential regulatory genes and critical hormones associated with bud germination. …”
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EVOLUTION OF CONFLICT STUDIES IN THE INTERNATIONAL SECURITY CONTEXT IN POST-SOVIET RUSSIA by A. I. Nikitin

“…Article analyses formation and development of the conflict studies in Russia as a sub-discipline within political sciences, on the edge between political theory and studies of international relations and international security. Article defines stages of formation of conflict studies in Russia, analyzes social request for studies of conflicts, considers influence of foreign and international institutes and research, both form the CIS and from other foreign countries, onto the conflict studies in Russia. …”
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The Essence and Approaches to the Interpretation of Law in the Works of Domestic Scholars by V. K. Antoshkina

“…It will provide a comprehensive approach to determining the main characteristics and nature of the law interpretation process at the present stage. To achieve that goal, the author used methods of analysis and synthesis to reflect the unity and difference of views on the phenomenon of the study, and also used a comparative legal method and a systematic one. …”
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Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3. by Chrissy H Roberts, Sandra Molina, Pateh Makalo, Hassan Joof, Emma M Harding-Esch, Sarah E Burr, David C W Mabey, Robin L Bailey, Matthew J Burton, Martin J Holland

“…<h4>Conclusions</h4>To explain the observations in the context of chlamydial infection and trachoma we propose a two-stage model of response and disease that balances the cytolytic response of KIR expressing NK cells with the ability to secrete interferon gamma, a combination that may cause pathology. …”
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European System for Cardiac Operative Risk Evaluation II and Liver Dysfunction by Andreea Ludusanu, Adelina Tanevski, Bogdan Mihnea Ciuntu, Razvan Lucian Bobeica, Dragos Andrei Chiran, Cristinel Ionel Stan, Viorel Dragos Radu, Vasile Lucian Boiculese, Grigore Tinica

“…<b>Background:</b> The importance of liver dysfunction in predicting mortality in patients undergoing cardiovascular surgery is an important topic due to the general desire to improve current risk scores such as EUROSCORE II (European System for Cardiac Operative Risk Evaluation), with EUROSCORE III being currently under development. The model for End-Stage Liver Disease (MELD) Score has already proven its utility in predicting outcomes for patients undergoing abdominal, cardiovascular or urological surgery. …”
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Effects of dietary digestible lysine levels in breeding Japanese quails on productive and reproductive performance, egg quality, blood metabolites and immune responses by Mohammad Amin Omary, Heydar Zarghi, Ahmad Hassanabadi

“…The estimated dLys requirement for FE was higher than those for EP and EM. During the peak stage of the first laying cycle, the dietary dLys level of 0.932% and a daily intake of 303 mg dLys/bird are sufficient for optimal performance.…”
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