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26121
3-MA attenuates collagen-induced arthritis in vivo via anti-inflammatory effect and autophagy inhibition
Published 2025-01-01“…A recent study showed autophagy modulation may be a novel strategy in the treatment of RA. 3-Methylademine (3-MA), is the most widely used autophagy inhibitor, which blocks autophagy at the initiation and maturation stages. The aim of this study is to evaluate the effect of 3-MA in collagen-induced-arthritis (CIA) mice and further elucidate how 3-MA attenuated inflammation, and cartilage/bone damage in arthritis. …”
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26122
Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma
Published 2021-01-01“…By the analysis of Bioinformation Databases, there was a significant interaction of FOXO4 down expression to clinical tumor stages and pathological grades in the patients with HNSCC. …”
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26123
Diagnosis-Based Hybridization of Multimedical Tests and Sociodemographic Characteristics of Autism Spectrum Disorder Using Artificial Intelligence and Machine Learning Techniques:...
Published 2022-01-01“…It is challenging to discover autism in the early stages of life, which prompted researchers to intensify efforts to reach the best solutions to treat this challenge by introducing artificial intelligence (AI) techniques and machine learning (ML) algorithms, which played an essential role in greatly assisting the medical and healthcare staff and trying to obtain the highest predictive results for autism spectrum disorder. …”
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26124
CSGD-YOLO: A Corn Seed Germination Status Detection Model Based on YOLOv8n
Published 2025-01-01“…This study further proposes a new module named C2f-UIB-iAFF based on the faster implementation of cross-stage partial bottleneck with two convolutions (C2f), universal inverted bottleneck (UIB), and iterative attention feature fusion (iAFF) to replace the original C2f in YOLOv8, streamlining model complexity and augmenting the feature fusion prowess of the residual structure. …”
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26125
A novel sustainable biocide against the fruit fly Drosophila suzukii made from orange peels
Published 2024-11-01“…The ability of the female flies to lay eggs within fruits of varying maturity stages, combined with the accelerated offspring development within warmer climates, results in rapid population growth. …”
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26126
Kynurenines and aerobic exercise capacity in chronic kidney disease: A cross-sectional and longitudinal study.
Published 2025-01-01“…<h4>Methods</h4>We included 102 patients with non-dialysis CKD stages 2-5 (CKD 2-3, n = 54; CKD 4-5, n = 48) and 54 healthy controls, age- and sex-matched with the CKD 2-3 group. …”
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26127
Satisfied with the worst health outcomes or unsatisfied with the best: explaining the divergence between good patient-reported outcomes and low satisfaction and vice versa among kn...
Published 2025-01-01“…Abstract Objectives Total knee arthroplasty (TKA) is an effective treatment for patients with end-stage knee osteoarthritis but some patients exhibit a discrepancy between patient-reported outcomes (PROs) and patient satisfaction (PS). …”
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26128
Radiation knowledge and anxiety levels among residents proximity to the world’s first AP1000 nuclear power unit
Published 2025-01-01“…ObjectiveAssess the level of radiation-related knowledge (RRK) and nuclear energy-related knowledge (NERK) among residents near the Sanmen Nuclear Power Plant, the first project adopted the Advanced Passive Pressurized Water Reactor (AP1000) technology.MethodsIn this study, respondents were selected using stratified multi-stage random sampling for residents aged 18 years and above living within 30 kilometers of the Sanmen Nuclear Power Station. …”
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26129
Using the Theory of Planned Behavior to Explain Expecting Couples Birth Preparedness Intentions in a Rural Setting: A Cross-Sectional Study from Rukwa, Southern Tanzania
Published 2018-01-01“…A community based cross-sectional study targeting pregnant women and their partners was performed from June until October 2017. A three-stage probability sampling technique was employed to obtain a sample of 546 couples A structured questionnaire based upon the Theory of Planned Behavior was used. …”
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26130
Applying the language acquisition model to the solution small language processing tasks
Published 2022-03-01“…The relevance of this task is due to the following considerations: the need to eliminate the information inequality between speakers of different languages; the need for new tools for the study of poorly understood languages, as well as innovative approaches to language modeling in the low-resource context; the problem of supporting and developing small languages.There are three main objectives in solving the problem of small natural language processing at the stage of describing the problem situation: to justify the problem of modeling language in the context of resource scarcity as a special task in the field of natural languages processing, to review the literature on the relevant topic, to develop the concept of language acquisition model with a relatively small number of available resources. …”
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26131
MANIPULATIVE TACTICS IMPLEMENTATION IN POLITICAL DISCOURSE
Published 2024-12-01“…The empirical material was interviews and individual statements of leading Russian and Western politicians, as well as the works of domestic and foreign political scientists and journalists presented in modern media. At certain stages of the study, in the course of the work, such research methods as discourse analysis, linguistic description, contextual and semantic analysis were used. …”
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26132
Translation, cross-cultural adaptation and psychometric evaluation of the Serbian Ankylosing Spondylitis Quality of Life (ASQoL) Questionnaire (refers to r-axSpA) and its relations...
Published 2025-01-01“…Abstract Objectives To translate, cross-culturally adapt and validate the Serbian Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire, e.g. according to the new nomenclature Radiographic-Axial Spondyloarthritis (r-axSpA), and to relate it to disease activity and functional status domains. Methods Four stages were accomplished: (1) Bilingual and lay panel for translation and cross-cultural adaptation (2) Cognitive debriefing interviews (assessing the language and cultural equivalence of the concepts used in the Serbian ASQoL translation) for face and content validity (3) Psychometric evaluation: (a) convergent validity by NHP as a comparator scale and (b) known group validity by correlations with disease activity and overall health status and reliability (internal consistency and test-retest reliability) (4) Independent regression analyses for relations between ASQoL and ASDAS, BASDAI, BASFI, Schober’s test, respiratory index and SPARCC were used. …”
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26133
Methodology for the organisation of professional training of senior citizens: general concept
Published 2021-04-01“…The obtained results allowed the author to conclude that at present stage of the Russian state and Russian society development, there is a need for scientific interdisciplinary knowledge, which substantiates the principles and didactic support of professional training of senior citizens in order to continue their active labour activity and to propose the concept for building the model for the organisation of such training. …”
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26134
2D Fast Vessel Visualization Using a Vessel Wall Mask Guiding Fine Vessel Detection
Published 2010-01-01“…We advocate that these changes can be addressed as subsequent stages of the same vessel detection procedure. We first carry out an initial estimate of the basic vessel-wall's network, define the main wall-body, and then try to approach the ridges and branches of the vasculature's using fine detection. …”
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26135
Integrated analysis of the transcriptome and hormone metabolome elucidates the regulatory mechanisms governing walnut bud germination
Published 2025-01-01“…By assessing hormone levels and gene expression at different developmental stages, we pinpointed potential regulatory genes and critical hormones associated with bud germination. …”
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26136
EVOLUTION OF CONFLICT STUDIES IN THE INTERNATIONAL SECURITY CONTEXT IN POST-SOVIET RUSSIA
Published 2016-10-01“…Article analyses formation and development of the conflict studies in Russia as a sub-discipline within political sciences, on the edge between political theory and studies of international relations and international security. Article defines stages of formation of conflict studies in Russia, analyzes social request for studies of conflicts, considers influence of foreign and international institutes and research, both form the CIS and from other foreign countries, onto the conflict studies in Russia. …”
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26137
The Essence and Approaches to the Interpretation of Law in the Works of Domestic Scholars
Published 2019-12-01“…It will provide a comprehensive approach to determining the main characteristics and nature of the law interpretation process at the present stage. To achieve that goal, the author used methods of analysis and synthesis to reflect the unity and difference of views on the phenomenon of the study, and also used a comparative legal method and a systematic one. …”
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26138
Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3.
Published 2014-03-01“…<h4>Conclusions</h4>To explain the observations in the context of chlamydial infection and trachoma we propose a two-stage model of response and disease that balances the cytolytic response of KIR expressing NK cells with the ability to secrete interferon gamma, a combination that may cause pathology. …”
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26139
European System for Cardiac Operative Risk Evaluation II and Liver Dysfunction
Published 2025-01-01“…<b>Background:</b> The importance of liver dysfunction in predicting mortality in patients undergoing cardiovascular surgery is an important topic due to the general desire to improve current risk scores such as EUROSCORE II (European System for Cardiac Operative Risk Evaluation), with EUROSCORE III being currently under development. The model for End-Stage Liver Disease (MELD) Score has already proven its utility in predicting outcomes for patients undergoing abdominal, cardiovascular or urological surgery. …”
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26140
Effects of dietary digestible lysine levels in breeding Japanese quails on productive and reproductive performance, egg quality, blood metabolites and immune responses
Published 2024-11-01“…The estimated dLys requirement for FE was higher than those for EP and EM. During the peak stage of the first laying cycle, the dietary dLys level of 0.932% and a daily intake of 303 mg dLys/bird are sufficient for optimal performance.…”
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