ALGORITHMIC THINKING IN HIGHER EDUCATION: DETERMINING OBSERVABLE AND MEASURABLE CONTENT by Marian Byrka, Andrii Sushchenko, Volodymyr Luchko, Galina Perun, Victoria Luchko

“…The study is a mixed-methods type of development research carried out in 4 stages: 1) extraction of the KSA statements from the extant scientific literature related to algorithmic thinking; 2) design of The Algorithmic Thinking Content Survey (ATCS) based on the five steps Universal Sequence of an Algorithm Development (USAD); 3) administration of the ATCS on a wide variety of educational professionals (N = 117); 4) data analysis aimed to obtain the content of algorithmic thinking in observable and measurable KSA statements. …”
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MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi. by Sajith Raghunandanan, Kai Zhang, Yan Zhang, Raj Priya, Ching Wooen Sze, Yongliang Lou, Michael J Lynch, Brian R Crane, Mark H Kaplan, Chunhao Li, X Frank Yang

“…In this study, we show that mcp5, a gene encoding one of the most abundant MCPs in B. burgdorferi, is differentially expressed in response to environmental signals and at distinct stages of the pathogen's enzootic cycle. Notably, mcp5 expression is regulated by the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, two key regulatory pathways that are critical for the spirochete's colonization of the tick vector and mammalian host, respectively. …”
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Predicting Poor Outcome of COVID-19 Patients on the Day of Admission with the COVID-19 Score by Luke Tseng, Erin Hittesdorf, Mitchell F. Berman, Desmond A. Jordan, Nina Yoh, Katerina Elisman, Katherine A. Eiseman, Yuqi Miao, Shuang Wang, Gebhard Wagener

“…The primary combined endpoint included intubation, stage 3 acute kidney injury (AKI), or death. Laboratory tests available on admission in at least 70% of patients (and age) were included for univariate analysis. …”
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Predicting survival rates: the power of prognostic nomograms in distal cholangiocarcinoma by Jiangfeng Hu, Yuping Shi, Lihua Jin, Suhong Yi, Jinsuo Chen, Dadong Wan, Weixin Ye, Jingnan Chen, Yajing Zhang, Yang Jiang, Bensong Duan, Yuwei Dong

“…Decision curve analysis was used to evaluate the model and its clinical applicability.ResultsThe findings demonstrated that Grade, M stages, Surgery, and Chemotherapy emerged as autonomous prognostic factors for the survival of individuals with dCCA. …”
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Nationwide carrier screening for congenital adrenal hyperplasia: integrated approach of CYP21A2 pathogenic variant genotyping and comprehensive large gene deletion analysis by Yossawat Suwanlikit, Bhakbhoom Panthan, Pawares Chitayanan, Sommon Klumsathian, Angkana Charoenyingwattana, Wasun Chantratita, Objoon Trachoo

“…Identifying at-risk couples during the preconception stage holds significance for optimizing reproductive choices. …”
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Silicone Foley's catheter: A useful splint in ear surgeries by Siddharth K. Karanth, Nitin J. Mokal

“…Maintenance of ear projection and post auricular sulcus in staged ear reconstruction in microtia is a trying problem. …”
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Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose–response meta-analysis by Paul Roderick, Peter Clive Hayes, Julie Parkes, Ryan Buchanan, Oliver John Kennedy, Jonathan Andrew Fallowfield

“…There was evidence that the association was not significantly altered by stage of liver disease or the presence/absence of high alcohol consumption, high body mass index, type 2 diabetes mellitus, smoking, or hepatitis B and C viruses. …”
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Development of autonomic innervation at the venous pole of the heart: bridging the gap from mice to human by Fleur Zwanenburg, Thomas A. Bos, Arend D. J. Ten Harkel, Monique C. Haak, Nathan D. Hahurij, Robert E. Poelmann, Conny J. van Munsteren, Lambertus J. Wisse, Nico A. Blom, Marco C. DeRuiter, Monique R. M. Jongbloed

“…Methods Wildtype mouse embryos (E9.5–E18.5) and healthy human fetuses (6–38 weeks gestational age (WGA)) were studied at sequential stages to obtain a comparative developmental series. …”
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Injectable Self-Assembling Procyanidin Nanospheres for Effective Osteoarthritis Treatment by Li G, He F, Feng J, Xu G, Wu C, Qiao Y, Liu Y, Chen H, Du P, Wang J

“…In an enzymolysis model of rat OA, PAs/PF127 nanospheres significantly reduce joint space swelling in the early stages of cartilage destruction and accelerate the formation of subchondral bone and cartilaginous surface.Implication: This study offers valuable insights into the preparation of novel PA nanospheres for effective repair of OA.Keywords: procyanidin, self-assembling nanospheres, injectable, osteoarthritis treatment…”
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The Identification and synthesis of metabolites of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide by Alexander L. Khokhlov, Ilya I. Yaichkov, Anton A. Shetnev, Valeria A. Panova, Julia A. Efimova, Sergey A. Ivanovskiy, Mikhail K. Korsakov, Nikita N. Volkhin, Sergey S. Petukhov

“…The structure of the obtained substances was confirmed by NMR spectroscopy and high-resolution mass spectrometry. At the final stage, animal biological fluids and model samples with the addition of the synthesized compounds were analyzed using HPLC-MS/MS to establish the structure of metabolites.Results and Discussion: N-hydroxy-4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide, 4-(5-(hydroxymethyl)-1,3,4-oxadiazole-2-yl)-benzenesulfonamide and 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonic acid were identified and synthesized. …”
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The Role of Leaders in Formulation of the Foreign Policy Identity in Egypt by I. E. Ibragimov

“…The predominance of various elements in ideological as well as worldview in the age of the rule of a particular president has led to noticeable differences in Egypt's foreign policy at the current stage. This article attempts to answer the following research questions: What place does of the institute of the heads of State in foreign policy decisions? …”
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Effective BCDNet-based breast cancer classification model using hybrid deep learning with VGG16-based optimal feature extraction by Meenakshi Devi P., Muna A., Yasser Ali, Sumanth V.

“…Aim The primary aim of the study is to design an effective breast cancer diagnosis model that can accurately classify tumors in their early stages, thus reducing mortality rates. The model aims to optimize the weight and parameters using the RPAOSM-ESO algorithm to enhance accuracy and minimize false negative rates. …”
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Describing quality of life trajectories in young Hispanic women with breast cancer: 5-year results from a large prospective cohort by Bryan F. Vaca-Cartagena, Ana S. Ferrigno Guajardo, Hatem A. Azim Jr, Federico Rotolo, Antonio Olivas-Martinez, Alejandra Platas, Alan Fonseca, Fernanda Mesa-Chavez, Marlid Cruz-Ramos, Ana Rodriguez, Alejandro Mohar, Cynthia Villarreal-Garza

“…Methods: In this prospective longitudinal cohort study, women aged ≤40 with stage I-III BC completed the European Organization for the Research and Treatment of Cancer Core QoL questionnaire at diagnosis and during 4 follow-up visits over 5 years, alongside demographic and clinical data collection. …”
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Examining the effect of direct-from-blood bacterial testing on antibiotic administration and clinical outcomes: a protocol and statistical analysis plan for a pragmatic randomised... by Li Wang, Wesley H Self, Todd W Rice, Matthew W Semler, Karen F Miller, Cheryl L Gatto, Andrea Fletcher, Romney M Humphries, Joanna L Stollings, Adrienne Baughman, Jakea Johnson, Edward T Qian, Mary Lynn Dear, David C Gaston, Ariel A Lewis, George E Nelson, Benjamin J Ereshefsky, Matthew A Christensen, Ritu Banerjee, Dan Albert, Alison Benton, Laura Bobbitt, Carleigh Burns, Timothy Duff, David C. Gaston, MLS Sharon Glover, Allyson Hobbie, Austin Ing, Gabriel Kemp, Sheryl Mangrum, Geoff Mavrak, Kelly Moser, David Mulherin, Shannon Pugh, Matthew Rodgers, Chrissie Schaeffer, Adam Turner, Sabrina Shipman, Halden Z VanCleave, Hamilton Wen Li Wang, LaKeysha Wiggins

“…Additional outcomes include highest stage of acute kidney injury, lowest platelet count and receipt of kidney replacement therapy within 14 days of randomisation, as well as hospital-free days, intensive care unit-free-days and all-cause, in-hospital mortality within 28 days of randomisation. …”
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The Effect of Waxing Options on Shelf Life and Postharvest Quality of “ngowe” Mango Fruits under Different Storage Conditions by Benson Maina, Jane Ambuko, Margaret J. Hutchinson, Willis O. Owino

“…A homogenous sample of mango fruits, variety “ngowe” harvested at mature green stage were subjected to two waxing treatments, namely Shellac or Decco wax™. …”
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Persistence and emergence of X4 virus in HIV infection by Ariel D. Weinberger, Alan S. Perelson

“…Approximately 50% of late-stage HIV patients develop CXCR4-tropic (X4) virus in addition to CCR5-tropic (R5) virus. …”
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Exploring physical activity preferences and motivation in long-term cardiac prevention: An Austrian cross-sectional survey. by Hannah McGowan, Johanna Gutenberg, Veronika Leitner, Kathrin Mühlhauser, Aliz Breda, Michael Fischer, Sebastian Globits, Vincent Grote, David Kiesl, Karl Mayr, Michael Muntean, Andrea Podolsky, Josef Niebauer, Rik Crutzen, Stefan Tino Kulnik

“…Cardiac rehabilitation (CR) patients often do not sustain physical activity (PA) behaviour in the long run, once they progress into a self-management stage of secondary prevention. This study aimed to explore former CR patients' PA preferences, determinants (i.e., influencing factors) and motivation for sustained PA engagement. …”
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Sensitivity Analysis of Wear on Metal-On-Metal Bearing Couples via Verification of Numeric and Analytic Methods by Alican Tuncay Alpkaya, Senay Mihcin

“…Contact pressure plays an important role in wear mechanisms and needs to be investigated in detail to obtain more accurate wear predictions to understand the wear performance of the implant in the design stage. This study proposes a methodology for verification of contact pressure and pressure distribution via numeric and analytic methods to be used in wear calculations. …”
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Integrated Three-Dimensional Structural and Petrophysical Modeling for Assessment of CO2 Storage Potential in Gas Reservoir by Syed Yasir Ali Shah, Jiangfeng Du, Sayed Muhammad Iqbal, Linze Du, Umair Khan, Baoyi Zhang, Jingqiang Tan

“…Three-dimensional structural modeling unveiled complex features, for example horsts, grabens, and half-grabens, formed through multiple deformation stages. Petrophysical modeling indicated promising reservoir characteristics, that is high porosity and permeability in the desired zone. …”
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Safe, effective and cost-effective oxygen saturation targets for children and adolescents with respiratory distress: protocol for a randomised controlled trial (OxyKids study) by Jolita Bekhof, Eleni-Rosalina Andrinopoulou, J Bosmans, Gerard Koppelman, Karlijn J van Stralen, Anja Vaessen-Verberne, Sam Louman, Caroline Brackel, Arvid W A Kamps, Ismé de Kleer, Walter Balemans, Mirjam Scheffer, Marianne Brouwer, Marije van den Beukel, Mariëlle W H Pijnenburg, Annemie L M Boehmer

“…Parents of patients and patient representatives are involved in all stages of the study, from design to results, interpretation and dissemination. …”
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