Adjuvant Therapy after Esophagectomy for Esophageal Cancer: Who Needs It?: Multi-institution Worldwide Observational Study by Siva Raja, MD, PhD, Thomas W. Rice, MD, Min Lu, PhD, Marie E. Semple, MPH, Andrew J. Toth, MS, Eugene H. Blackstone, MD, Sudish C. Murthy, MD, PhD, Usman Ahmad, MD, Michael McNamara, MD, Hemant Ishwaran, PhD, for the Worldwide Esophageal Cancer Collaboration Investigators

“…We sought to obtain a granular estimate of patient-level risk-adjusted survival for each therapeutic option by cancer histopathology and stage. Background:. Although esophagectomy alone is now an uncommon therapy for treating locally advanced esophageal cancer, the value of adjuvant therapy after esophagectomy is unknown. …”
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Lifetime risks of kidney donation: a medical decision analysis by Bryce A Kiberd, Karthik K Tennankore

“…Objective This study estimated the potential loss of life and the lifetime cumulative risk of end-stage renal disease (ESRD) from live kidney donation.Design Markov medical decision analysis.Setting USA.Participants 40-year-old live kidney donors of both sexes and black/white race.Intervention Live donor nephrectomy.Main outcome and measures Potential remaining life years lost, quality-adjusted life years (QALYs) lost and added lifetime cumulative risk of ESRD from donation.Results Overall 0.532–0.884 remaining life years were lost from donating a kidney. …”
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Neuroendocrine Neoplasms of the Gallbladder: A Clinicopathological Analysis of 13 Patients and a Review of the Literature by Pengyan Wang, Jingci Chen, Ying Jiang, Congwei Jia, Junyi Pang, Shan Wang, Xiaoyan Chang

“…Kaplan-Meier’s analysis demonstrated that liver metastasis and TNM stage III-IV were associated with decreased OS (P<0.05), whereas age, sex, tumor size, grade of the neuroendocrine component, lymph node metastasis, and adjuvant chemotherapy were not significantly prognostic indicators of OS. …”
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Cloning and Functional Analysis of <i>BraTSD2</i> Associated with Root Swelling in Turnip (<i>Brassica rapa</i> L.) by Wenyue Huang, Shifan Zhang, Fei Li, Hui Zhang, Rifei Sun, Guoliang Li, Shujiang Zhang

“…Temporal and spatial expression analysis of <i>BraTSD2</i> using qPCR techniques indicated that the <i>BraTSD2</i> gene had the highest expression levels in roots and hypocotyls during the swelling stage. Analysis of the promoter cis-acting elements of the <i>BraTSD2</i> gene revealed that the promoter is regulated by signals associated with light response, abscisic acid, stress, salicylic acid, and MYBHI. …”
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…Innovative immunotherapy modalities, including adoptive immune cell therapy, tumor vaccines, and non-specific immunomodulators therapy, and oncolytic viruses have shown promise in early-stage clinical trials for GC. Clinical trials have supported that targeted therapy and immunotherapy can significantly improve the survival and quality of life of GC patients. …”
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Nouveaux modèles de formation et enseignement supérieur : l’exemple du tutorat à l’université by Emmanuelle Annoot

“…This assistance occurs at several stages of the student’s progress (support for orientation, for undergraduate adaptation, step by step progression in a renewed degree, support for finding a job) in relationship with goals set according to the level of achievement to be reached by the student in the course of his studies (skills specific to subjects and generic skills). …”
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Automated process assessment of primary healthcare for hyperlipidemia: preliminary findings and implications form Anhui, China by Ningjing Yang, Yuning Wang, Ying Li, Dongying Xiao, Ruirui Cui, Nana Li, Rong Liu, Jing Chai, Xingrong Shen, Debin Wang

“…The procedure-based measures were derived from specific quality-facts of 21 stages/procedures (e.g., lipid lowering medication prescription) using self-designed algorithms. …”
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Safe development of coordination abilities in 11-year-old basketball players through aerobics by Vladyslav Heitenko, Volodymyr Prystynskyi, Tetyana Prystynska

“…The purpose of the study is to analyze the impact of aerobics training on the coordination abilities of basketball players at the initial training stage. Materials and methods. The study involved 11-year-old basketball players (n=30). …”
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Analysing Methods of Measuring the Level of Development Based on the Experimental Data by Farzad Karimi, Mostafa Ahmadvand, Ali Heidari

“…In addition, 69.35 percent of population in villages of the study was in developing stage.…”
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Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics by Jianpeng Li, Yunzhong Jiang, Minghai Ma, Lu Wang, Minxuan Jing, Zezhong Yang, Mengzhao Zhang, Ke Chen, Jinhai Fan

“…Targeting intermediate exhaustion states may restore T cell function and improve anti-tumor immunity. …”
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Health Care Costs attributable to Hospital-diagnosed Back Pain: A Longitudinal Register-based Study of the Danish Population by Rikke Søgaard, Jan Sørensen

“…**Conclusion:** At the disease stage where back pain leads to contact with specialised health care, diseased individuals appear to use on average three times more health care than non-diseased individuals. …”
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Efficient Excavation and Support Cooperation Technology for Surrounding Rock of Deep Buried Long-Distance and Large Section Gob-Side Roadway: A Case Study by Houqiang Yang, Changliang Han, Nong Zhang, Xudong Li, Yitao Liu, Wentao Liu, Kai Song, Yuxin Guo, Wei Yao

“…Supposed that upon the heading face support is completed, the next excavation-support cycle is quickly started during the early stage of stress adjustment, and the time effect can be fully utilized to alleviate the disturbance intensity of the advanced abutment stress in the heading face, as well as reduce the damage of rock mass. …”
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THE DIETARY PATTERNS AND THE RISK OF BREAST CANCER by L. A. Radkevich, D. A. Radkevich

“…Malnutrition in the early stages of life cause hypomotilinemia and shape the epigenome, and does not change the genetic code. …”
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Alström syndrome: the journey to diagnosis by Akshat Sinha, Kerry Leeson-Beevers, Catherine Lewis, Elizabeth Loughery, Tarekegn Geberhiwot

“…Symptoms can also present at different stages, making diagnosis difficult. There are currently 88 people diagnosed with AS in the UK. …”
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The systemic oxidative stress index predicts clinical outcomes of esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy by Jifeng Feng, Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen, Qixun Chen

“…Patients with low SOSI had better DFS (55.1% vs. 85.5%, P&lt;0.001) and OS (72.6% vs. 79.1%, P=0.013). Then, a new staging that included TNM and SOSI based on RPA algorithms was produced. …”
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Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis by Xiaolong Qi, Min An, Tongwei Wu, Deke Jiang, Mengyun Peng, Weidong Wang, Jing Wang, Chunqing Zhang, on behalf of the CHESS Study Group

“…The hepatitis B virus infection is a global health issue and the stage of liver fibrosis affects the prognosis in patients with chronic hepatitis B (CHB). …”
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Vδ2 T-cells response in people with Mpox infection: a three-month longitudinal assessment by Eleonora Cimini, Eleonora Tartaglia, Francesco Messina, Andrea Coppola, Valentina Mazzotta, Massimo Tempestilli, Giulia Matusali, Stefania Notari, Annalisa Mondi, Gianluca Prota, Alessandra Oliva, Carla Fontana, Enrico Girardi, Fabrizio Maggi, Andrea Antinori

“…The presence of effector/activated Vδ2 T-cells in the early stages of Mpox infection and their capability to activate quickly, producing pro-inflammatory cytokines, may be useful to enhance the early adaptive response to human Mpox, maintaining a protective memory/effector T-cell response.…”
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BODY AND SPACE RELATIONSHIP IN THE RESEARCH FIELD OF PHENOMENOLOGICAL ANTHROPOLOGY: BLUMENBERG’S CRITICISM OF EDMUND HUSSERL’S “ANTHROPOLOGY PHOBIA” by V. Prykhodko, S. Rudenko

“…Conclusions show the following state of affairs demonstrated by the anthropological and performative shift towards the body theme: 1) absolutisation of space without mentioning its relation to body experience is unreasonable and groundless, like in Husserl’s “anthropology phobia ”; 2) since the ground itself is a metaphorical anthropology basis, anthropology can reveal the structural conditions of perception due to thematic fronting of embodiment; 3) this gives anthropology some compensational features, to avoid false culture and nature dualism; 4) so, the space and body relationship is expressed by the Vehikel-phenomenon (transport phenomenon) of the body itself, by placing, arranging and depicting, and thus replacing something missing and unavailable for direct contemplation, by revealing the spatial infrastructure for object perception, creating the presence conditions and metaphorically marking the contemplation boundary; 5) the depicting arrangement (Darstellung) is at the same time a bodily performance, a play, staging and performing, which gives an aesthetic, poetic and emphatic impact on the use of philosophy language, in our case, on the way a phenomenology philosopher works with the language.…”
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Enhancement of Cytomegalovirus-Specific Cytokine Production after Modulation of the Costimulation in Kidney Transplant Patients by Theresa Dornieden, Benjamin Wilde, Johannes Korth, Kai Werner, Peter A. Horn, Oliver Witzke, Monika Lindemann

“…Kidney transplantation is the therapy of choice for patients with end stage renal disease. Due to immunosuppressive treatment, patients are at risk for opportunistic infections. …”
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Factors influencing osteoradionecrosis progression during hyperbaric oxygen therapy: A case study [version 2; peer review: 1 approved, 2 approved with reservations] by Khadija Bahrini, Chaima Zitouni, Sameh Mezri, Hedi Gharsallah, Wiem Boughzala, Mounir Haggui

“…Analysis of factors influencing ORN progression on the univariate study revealed significant associations with high blood pressure (p=0.046), larger tumor size (p=0.004), advanced tumor stages (p=0.048), mean radiation dose (p=0.002), delays between dental care and radiotherapy (p=0.045), and the location of ORN within the mandible (p=0.049). …”
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