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  1. 25581
  2. 25582

    PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands by Vasudha Mishra, Alka Singh, Michael Korzinkin, Xiangying Cheng, Claudia Wing, Viktoria Sarkisova, Ashwin L. Koppayi, Alexandra Pogorelskaya, Oksana Glushchenko, Manu Sundaresan, Venkat Thodima, Jack Carter, Koichi Ito, Peggy Scherle, Anna Trzcinska, Ivan Ozerov, Everett E. Vokes, Grayson Cole, Frank W. Pun, Le Shen, Yuxuan Miao, Alexander T. Pearson, Mark W. Lingen, Bruce Ruggeri, Ari J. Rosenberg, Alex Zhavoronkov, Nishant Agrawal, Evgeny Izumchenko

    Published 2025-01-01
    “…Given its protracted growth, ACC is usually diagnosed in advanced stage. Treatment of ACC is limited to surgery and/or adjuvant radiotherapy, which often fails to prevent disease recurrence, and no FDA-approved targeted therapies are currently available. …”
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  3. 25583

    Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis by Işıl Peker, Hacer Eroğlu İçli, Belgin Mutluay, Burcu Yüksel, Zeynep Özdemir, Mesrure Köseoğlu, Aysu Şen, Dilek Ataklı, Aysun Soysal, Musa Öztürk

    Published 2024-12-01
    “…Although these chemokines are not specific to MS, higher levels may signal disease activity, severity, and transition to more progressive stages.…”
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  4. 25584

    Changes in IL-16 Expression in the Ovary during Aging and Its Potential Consequences to Ovarian Pathology by Jessica Ramirez, Pincas Bitterman, Sanjib Basu, Animesh Barua

    Published 2022-01-01
    “…In addition, tumor tissues from patients with ovarian high-grade serous carcinoma at early stage (n=5) were also used as reference tissue for comparing the expression of several selected markers in aging ovaries. …”
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  5. 25585

    Metabolome profiling dissects the oat (Avena sativa L.) innate immune response to Pseudomonas syringae pathovars. by Chanel J Pretorius, Paul A Steenkamp, Ian A Dubery

    Published 2025-01-01
    “…At the seedling growth stage, metabolic alterations in the Dunnart oat cultivar (tolerant to Ps-c) in response to inoculation with the respective P. syringae pathovars were examined following perception and response assays. …”
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  6. 25586

    Reasonable Support Parameters for Loess Tunnel Under Different Water Contents: A Case Study by Hao Chen, Yanbin Luo, Jianxun Chen, Hui Chen, Yanfeng Li, Pengkun Wang, Lele Guo

    Published 2025-01-01
    “…The crown settlement of the loess tunnel exceeds the horizontal convergence, and the deformation behavior can be categorized into three distinct stages: rapid growth, continuous growth, and slow growth. …”
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  7. 25587

    Echocardiographic phenotypes of diabetic myocardial disorder: evolution over 15 months follow-up in the ARISE-HF trial by Thomas H. Marwick, Carolyn Lam, Yuxi Liu, Stefano Del Prato, Julio Rosenstock, Javed Butler, Justin Ezekowitz, Nasrien E. Ibrahim, W. H. Wilson Tang, Faiez Zannad, Riccardo Perfetti, James L. Januzzi

    Published 2025-01-01
    “…Abstract Background Diabetic myocardial disorder (DbMD, evidenced by abnormal echocardiography or cardiac biomarkers) is a form of stage B heart failure (SBHF) at high risk for progression to overt HF. …”
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  8. 25588

    UAV-Based Survey of the Earth Pyramids at the Kuklica Geosite (North Macedonia) by Ivica Milevski, Bojana Aleksova, Slavoljub Dragićević

    Published 2024-12-01
    “…Following this procedure, more than 140 earth pyramids were delineated, ranging in height from 1 to 2 m and to 30 m at their highest. At this stage, a very accurate UAV-based 3D model of the most remarkable earth pyramids was developed (the accuracy was checked using the iPhone 14 Pro LiDAR module), and their morphometrical properties were calculated. …”
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  9. 25589

    The "conquest" of historical space in the 21st century Russia: negative historical identity? by Aurimas Švedas

    Published 2009-12-01
    “…In recent years all these components of sociopolitical identity have been used by the politicians of the Kremlin, the political scientists, and public relations' specialists as an instrument for the production of a peculiar formation – the "state patriotism." The intellectual foundations of the "state patriotism" in the sphere of political science are such terms as "energetic superpower" and "sovereign democracy," which were used simultaneously in order to present Russia on the international stage and to provide the state regime – the vertical of power – with meaningfulness in the eyes of the inhabitants of the state. …”
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  10. 25590

    Cultivatable Bacteriota of Chronic Wound of Patients with Diabetic Foot Syndrome with Critical Limb Ischemia Based on Wound Biopsy in Peri-Revascularization Period by Syedah Sarah Hussaini, Fran Dominic Grubesa, Mateusz Gajda, Martyna Schönborn, Katarzyna Bogucka, Mikołaj Maga, Paweł Maga, Jadwiga Wójkowska-Mach

    Published 2025-01-01
    “…Optimizing clinical environments (enhancing blood flow and controlling inflammation) in general over focusing singularly on microbiota composition or revascularization seems to be crucial and arguably outweighed the impact of microbial change alone; in particular, reperfusion may increase the conditions to bacterial growth at the first stage.…”
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  11. 25591

    Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis by E.A. Burylova, L.A. Mamaeva, A.S. Berdnikova, O.K. Fedorova

    Published 2021-03-01
    “…&nbsp;Fedorova</b> </p> <p> <b>Ural Scientific Research Institute of Phtysiopulmonology — Branch of the National Medical Research Center of Phtysiopulmonology, Yekaterinburg, Russian Federation</b> </p> <p> <b>Abstract</b> </p> <p> <i>Ocular manifestations of systemic sarcoidosis may emerge at any disease stage. Ocular sarcoidosis is typically characterized by uveitic presentations that predominantly involve the choroid of anterior eye segment. …”
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  12. 25592

    Efficacy and safety of new protease inhibitor faldaprevir in treatment of hepatitis C by M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin

    Published 2013-12-01
    “…Faldaprevir has demonstrated equally good tolerability, high safety and antiviral activity in patients at different stages of fibrosis and liver cirrhosis in the range of interferon-free treatment modes.Conclusion. …”
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  13. 25593

    Enhanced expression of ten‐eleven translocation 1 reverses gemcitabine resistance in cholangiocarcinoma accompanied by a reduction in P‐glycoprotein expression by Chuanxu Wang, Hua Ye, Lei Zhang, Yayu Cheng, Shifeng Xu, Ping Zhang, Zijie Zhang, Jimin Bai, Fangkang Meng, Lin Zhong, Guangjun Shi, Hao Li

    Published 2019-03-01
    “…Furthermore, multivariate Cox regression analysis indicated that TET1 expression and TNM stage were independent risk factors (P < 0.001) for the clinical outcomes of CCA patients with chemotherapy. …”
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  14. 25594

    USING A DIDACTIC TOOL WITH IT-SUPPORT FOR TEACHING GEOGRAPHY IN A SPECIAL SCHOOL IN SLOVAKIA by Viktor Hladush, Slávka Bendíková, Barbora Kovačova, Marcela Čarnická

    Published 2023-10-01
    “…As an example, the article briefly highlights the essence of the preparatory stage and the specific sequence of the teacher's work when studying one section «Slovakia». …”
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  15. 25595

    Protocol for a randomised ‘screen-and-treat’ Helicobacter pylori eradication trial in 14–18-years-old adolescents residing in three regions of Chile: effectiveness and microbiologi... by Ximena Aguilera, Camila Cabrera, Sergio George, Yalda Lucero, Beatriz Zabala Torres, Lilian Fernández, Nora Mamani, Anne Lagomarcino, Miguel O'Ryan

    Published 2025-01-01
    “…Introduction Gastric cancer is a major global health concern, being the final stage of a long-term process, primarily associated with Helicobacter pylori (H. pylori) infection. …”
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  16. 25596

    Impact of Age on Short- and Long-Term Outcomes after Pancreatoduodenectomy for Periampullary Neoplasms by Mario Gruppo, Francesca Tolin, Boris Franzato, Pierluigi Pilati, Ylenia Camilla Spolverato, Francesca Zingales, Imerio Angriman, Romeo Bardini

    Published 2020-01-01
    “…No significance was shown for diabetes, radicality of resection, stage of disease, operative time, length of stay, postoperative complications according to the Clavien-Dindo Score, postoperative mortality, pancreatic fistula, and reoperation rates. 69.9% of the patients in group I underwent adjuvant treatment vs. 39.4% of the older ones (p=0.012). …”
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  17. 25597

    Outdoor education wzmocnieniem realizacji zrównoważonego rozwoju by Małgorzata Jagodzińska, Anna Strumińska-Doktór

    Published 2019-12-01
    “…Pedagogika Outdoor education (OE) staje się coraz bardziej popularna, w Polsce przyjmuje różne nazwy: edukacja na świeżym powietrzu, edukacja poza klasą, edukacja plenerowa, zajęcia terenowe, pedagogika przygody. …”
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  18. 25598

    Changes in the prevalence of severe anxiety and depression symptoms and the associated factors in adults living in Manaus: a comparison of two cross-sectional studies conducted in... by Vanessa Gomes Lima, Marcus Tolentino Silva, Gustavo Magno Baldin Tiguman, Taís Freire Galvão

    Published 2024-12-01
    “…DESIGN AND SETTING: This cross-sectional study included adults living in Manaus selected through a three-stage probability sampling in 2015 and 2019. METHODS: This is an analysis of two surveys conducted. …”
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  19. 25599
  20. 25600

    Enhancement of Fertilizer Efficiency Through Chinese Milk Vetch and Rice Straw Incorporation by Tahir Shah, Adnan Anwar Khan, Yahya Mohammed Ali Aljerib, Muhammad Tariq, Donghui Li, Mingjian Geng, Yajun Gao, Qiang Zhu

    Published 2025-01-01
    “…Soil organic matter (SOM), total nitrogen (TN), ammonium N (NH<sub>4</sub><sup>+</sup>-N), nitrate N (NO<sub>3</sub><sup>−</sup>-N), available phosphorus (AP), and available potassium (AK) contents were significantly enhanced under MSF80 across different growth stages in both 2020 and 2021 seasons over F100. Pearson correlation analysis revealed a strong positive correlation among SOM, TN, NH<sub>4</sub><sup>+</sup>-N, AP, AK, and rice yield. …”
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