A Morphological and Immunohistochemical Study of the Tumoral and Inflammatory Cells in Pancreatic Ductal Adenocarcinoma by Vlad Herlea, Elena Stoica Mustafa, Andreea Cristina Iorgescu, Nicolae Catalin Pechianu, Dragos Cretoiu, Maria Sajin, Simona Olimpia Dima, Catalin Vasilescu, Cezar Stroescu, Constantin Ungureanu, Traian Dumitrascu, Vladislav Brasoveanu, Minerva Ghinescu, Irinel Popescu

“…Patients presented with early stages (IA and IB), with low pathologic grade (G1), with small size tumors (less than 1-1.5 cm), with tumors located in the head of the pancreas, (p53: negative; p21: positive; and CD 68: positive in peritumoral tissue), with low nuclear index (Ki 67<10%), without metastases at the time of surgery (had a better prognosis), and with a survival rate of about 7 months. …”
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Integrating single cell analysis and machine learning methods reveals stem cell-related gene S100A10 as an important target for prediction of liver cancer diagnosis and immunothera... by Shenjun Huang, Tingting Tu

“…BackgroundHepatocellular carcinoma (LIHC) poses a significant health challenge worldwide, primarily due to late-stage diagnosis and the limited effectiveness of current therapies. …”
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Genome Sequencing Providing Molecular Evidence of Tetrapolar Mating System and Heterothallic Life Cycle for Edible and Medicinal Mushroom <i>Polyporus umbellatus</i> Fr. by Shoujian Li, Youyan Liu, Liu Liu, Bing Li, Shunxing Guo

“…Additionally, the number of sterigma and basidiospores on each basidium was examined using scanning electron microscopy, while the nuclei of basidiospores and basidia at various developmental stages were analyzed through DAPI staining. This research clarifies the heterothallic life cycle of <i>P. umbellatus</i>. …”
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Race as a prognostic factor of breast mucinous carcinoma by Dingyuan Wang, Yang Wang, Songlin Gao, Rongshou Zheng, Guijian Wu, Jianping Wang, Can Lu, Kena Bu, Chun Zhang, Wanqing Chen, Bailin Zhang

“…Results Asian American BMC patients were younger at diagnosis and had more favorable tumor grade and stage compared to other racial groups. After adjusting for clinicopathological factors and treatments, Asian American BMC patients exhibited significantly better overall survival (OS) than black (HR = 1.53, 95% CI: 1.05–2.22, P = 0.027) and white patients (HR = 1.41, 95% CI: 1.03–1.94, P < 0.001). …”
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Lessons Learned from Van Earthquake in the Context of Urban Environment and Health by Bilge Kalanlar

“…The urban environment and health in terms of effective planning done in the earthquake, epidemiological analysis of risk factors for death and injury, the necessary information for emergency needs assessment in earthquake rescue operations, management of losses, medical supplies, disease control and pre-earthquake sanitation and foreign aid issues, during and after disasters, including all stages of disaster should be evaluated and planned in advance. …”
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Adult Height after Growth Hormone Treatment at Pubertal Onset in Short Adolescents Born Small for Gestational Age: Results from a Belgian Registry-Based Study by M. Thomas, D. Beckers, C. Brachet, H. Dotremont, M.-C. Lebrethon, P. Lysy, G. Massa, N. Reynaert, R. Rooman, S. van der Straaten, M. Roelants, J. De Schepper

“…Short SGA adolescents starting GH therapy at an early pubertal stage have a modest and variable height gain. A normal AH can be expected in one third of the patients, especially in those with a smaller height deficit at onset of GH treatment.…”
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Immunosuppressive Phenotype of Esophagus Tumors Stroma by Olga V. Kovaleva, Madina A. Rashidova, Daria V. Samoilova, Polina A. Podlesnaya, Valeria V. Mochalnikova, Alexei Gratchev

“…We found that FOXP3 expression was associated with age (p=0.042) and iNOS expression was associated with the disease stage (p=0.044). In addition, FOXP3 and CD163 appeared to be markers of good prognosis (HR=0.4420, p=0.0325, and HR=0.4447, p=0.0456, respectively). …”
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Innovative surgical and stress-stimulated rat model of ligamentum flavum hypertrophy by Long Chen, Zhaoyuan Zhang, Niandong Li, Wanxia Zhang, Zhouhang Zheng, Yu Zhang

“…Background and purposeAnimal models of LFH are still in the exploratory stage. This study aimed to establish a reliable, efficient, and economical model of LFH in rats for the study of human ligamentum flavum (LF) pathological mechanisms, drug screening, development, improvement of surgical treatment, disease prevention, and other aspects.Methods and materialsForty rats were divided into an experimental group and a sham group of 20 rats. …”
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Metabolic engineering of Yarrowia lipolytica for the production and secretion of the saffron ingredient crocetin by Tingan Zhou, Young-Kyoung Park, Jing Fu, Piotr Hapeta, Cinzia Klemm, Rodrigo Ledesma-Amaro

“…This work not only represents a high production of crocetin, but also entails a significant simultaneous zeaxanthin production, setting the stage for sustainable and cost-effective production of these valuable compounds.…”
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Neuroplasticity and Neuroprotective Effect of Treadmill Training in the Chronic Mouse Model of Parkinson’s Disease by Ewelina Palasz, Wiktor Niewiadomski, Anna Gasiorowska, Anna Mietelska-Porowska, Grazyna Niewiadomska

“…Results of this study support the view that physical activity may be neuroprotective even at a more advanced stage of PD and justify starting physical activity at any point of the disease.…”
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Exploring Key Elements and Performance of BIM and VR Technologies in the Project Management of Assembled Buildings by Zhi-hong He, Tao Liu

“…Since the reform and opening up, the construction industry in China has been in a state of continuous expansion to promote economic and social development. …”
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Assessment of endometrial carcinoma on biopsy as a predictor of final surgical pathology: Are we doing it right? A completed audit cycle and recommendations by Aneeta Jassar, Nour Hemali, Anjali Bhatnagar

“…Background: Typing and grading of endometrial carcinomas (ECs) on small biopsy specimens is crucial to determine the need for full surgical staging. Histological subtype and grade are key factors available for risk stratification before surgery. …”
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Methodologische Probleme in der phonetischen Forschung des Polnischen als Fremdsprache by Alicja Derych

“…The analysis may serve as a starting point both at the stage of planning one’s research, and evaluation of specific problems that were already encountered.…”
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Identification and analysis of factors affecting the maturity of knowledge-based companies in the food industry with the approach of the fourth-generation industry by Ali Mohaghar, Fatemeh Saghafi, Mohammad Hasan Maleki, Daryamehr Keshani

“…Interviews with focus groups were also used to provide practical suggestions.Findings: The present research was carried out in several stages. In the first step, factors affecting the maturity of knowledge-based companies in the food industry were extracted through literature review and interviews with experts. …”
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Exploring the Potential of Malvidin and Echiodinin as Probable Antileishmanial Agents Through In Silico Analysis and In Vitro Efficacy by Luis Daniel Goyzueta-Mamani, Daniela Pagliara Lage, Haruna Luz Barazorda-Ccahuana, Margot Paco-Chipana, Mayron Antonio Candia-Puma, Gonzalo Davila-Del-Carpio, Alexsandro Sobreira Galdino, Ricardo Andrez Machado-de-Avila, Rodolfo Cordeiro Giunchetti, Edward L. D’Antonio, Eduardo Antonio Ferraz Coelho, Miguel Angel Chávez-Fumagalli

“…Malvidin demonstrated greater potency than echioidinin across all parasite stages and species. Against <i>L. amazonensis</i>, malvidin’s IC₅₀ values were 197.71 ± 17.20 µM (stationary amastigotes) and 258.07 ± 17 µM (axenic amastigotes), compared to echioidinin’s 272.99 ± 29.90 μM and 335.96 ± 19.35 μM. …”
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Rapid Destructive Arthropathy of the Knee in Parkinson’s Disease with Pisa Syndrome: A Case of Knee-Spine Syndrome by Hirokazu Takai, Masato Kitajima, Seiko Takai, Tomoki Takahashi, Ken-ichi Katsura, Makoto Tokunaga, Susumu Watanabe

“…A 60-year-old woman with Parkinson’s disease (PD; Hoehn-Yahr stage IV) had severe knee pain with moderate lateral osteoarthritis of the knee (Kellgren-Lawrence classification grade II). …”
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Аcute posterior vitreous detachment by P.L. Volodin, S.I. Belyanina

“…In most cases, the early stages of acute PVD are asymptomatic. Patients do not seek for medical care until an acute condition occurs along with the development of typical symptoms. …”
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Development of a multi-laboratory integrated predictive model for silicosis utilizing machine learning: a retrospective case-control study by Guo-kang Sun, Yun-hui Xiang, Lu Wang, Pin-pin Xiang, Zi-xin Wang, Jing Zhang, Ling Wu

“…Moreover, the diagnostic accuracies of the logistic model in silicosis stages 1, 2, and 3 were 88.0, 95.4, and 94.3% with an AUC of 0.968, 0.983, and 0.990 for silicosis, respectively.ConclusionA diagnostic model based on DD, A/G, LDH and WBC is successfully proposed for silicosis diagnostics. …”
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Breast Cancer Survivors’ Diet and Physical Activity Preferences and Barriers: How COVID-19 Changed the Intervention Landscape by Xin Chen, Chungyi Chiu, Helen Hoi Ting Cheung, Sylvia L Crowder, Xi Chen, Linda Trinh, Anna E Arthur

“…Methods: A cross-sectional survey was administered to adults diagnosed with ductal carcinoma in situ or stage I–IV breast cancer (BC) from 2019 to 2021 regarding interest, preferences, and barriers to participating in diet and exercise interventions. …”
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China’s peacekeeping activities within the UN: Features, challenges, and prospects by Qian Li

“…The first section of the paper examines the key stages in the development of the PRC’s approaches to peacekeeping. …”
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