Andrographolide prevents acute hyperammonemia-induced motor dysfunction in rats. Evidences for its mechanism of action by Arghya Mukherjee, Santosh Singh

“…Background: Beside the cirrhotic one, non-cirrhotic hyperammonemia (HA) can also cause neuro-degeneration and establishment of 'Hyperammonemic Encephalopathy', ultimately leading to the coma stage. We have done pilot study on aqueous extract of Andrographis paniculata herb against HA induced oxidative stress in rats. …”
Get full text

Gas Hydrate Accumulation and Occurrence Associated with Cold Seep Systems in the Northern South China Sea: An Overview by Wei Zhang, Jinqiang Liang, Qianyong Liang, Jiangong Wei, Zhifeng Wan, Junxi Feng, Wei Huang, Jing Zhao, Miaomiao Meng, Wei Deng, Chongmin Chen

“…Cold seep systems are present in diverse stages of evolution and exhibit various seabed microgeomorphic, geological, and geochemical features. …”
Get full text

Impact of polygeNic risk score for glaucoma on psycHosocial ouTcomes (INSiGHT) study protocol. by Giorgina Maxwell, Robert Allen, Simone Kelley, Lucinda Hodge, Georgina L Hollitt, Mathias Seviiri, Daniel Thomson, Joshua Schmidt, Jamie E Craig, Sarah Cohen-Woods, Emmanuelle Souzeau

“…This is largely due to the early stages of disease being asymptomatic; current population-based screening measures being unsupported; and a lack of current efficient prediction models. …”
Get full text

Activity of gemmogenesis in regenerated plants of hazelnut cv. ‘Akademyk Yablokov’ and antibiotic therapy for elimination of bacterial contamination <i>in vitro</i> by T. A. Krasinskaya

“…The plants produced during this study were included in the duplicate ex situ collection of nut crops preserved in vitro in the active growth state. Results. Single exposure to the antibiotic kanamycin monosulfate at a concentration of 100 mg/L during antibiotic therapy in the stage of in vitro micropropagation eliminated bacterial infection in 83.3% of regenerated plants, and twofold exposure in 100%. …”
Get full text

Syphilitic aortitis: from the past to the present (view of a dermatovenerologist) by S.V. Zakharov, T.V. Svyatenko, V.K. Zakharov, V.V. Gorbuntsov, L.A. Pohrebniak

“…Syphilitic aortitis with symptoms of cardiovascular damage, which are caused by aortic valve insufficiency, narrowing of the ascending coronary arteries, aneurysmal dilatation of the ascending part and aortic arch, occurs in the late stages of syphilitic infection. Even in patients with syphilis who have been treated in the past with penicillin drugs, cardiovascular damage may occur, namely aortitis with aortic valve insufficiency. …”
Get full text

Efficacy of probiotic Bacillus licheniformis DSM 28710 on performance and the mitigation of Clostridium perfringens-induced necrotic enteritis in broiler chickens by W. Van der Veken, V. Hautekiet, E.A. Kimminau, C. Hofacre, G.F. Mathis

“…Birds fed B-Act had significantly (P<0.05) lower NE lesions compared to the control and OXT group on day 21, although OXT was not supplemented to the animals at this stage yet. Both B-Act and OXT groups had significantly (P<0.05) lower NE scores than the control on day 28, demonstrating the effectiveness of the antibiotic treatment and the mitigating effect of B-Act on the effects of a Clostridium perfringens induced NE challenge.…”
Get full text

Microwave Thermal Ablation in an Unusual Case of Malignant and Locally Advanced Rare Tumor of Pancreas in ASA IV Old Male Patient and Literature Review by Francesco D’Amico, Michele Finotti, Chiara Di Renzo, Alessio Pasquale, Alessandra Bertacco, Giorgio Caturegli, Gabriel E. Gondolesi, Umberto Cillo

“…One month after the treatment, a staging CT scan was performed showing the size of the cephalopancreatic lesion had decreased from 43 to 35 mm with signs of complete ablation. …”
Get full text

Surgical Aspects of Split Liver Transplantation: а Review by S. V. Gautier, R. A. Latypov, A. R. Monakhov

“…To analyse the surgical aspects of performing a split liver transplantation in patients with end-stage liver disease.Key findings. Split liver transplantation (SLT) is a technique allowing two functional grafts to be obtained from one deceased donor to simultaneously save the lives of two recipients. …”
Get full text

Forest Attribute Dynamics in Secondary Forests: Insights for Advancing Ecological Restoration and Transformative Territorial Management in the Amazon by Carlos H. Rodríguez-León, Armando Sterling, Amelia Trujillo-Briñez, Yerson D. Suárez-Córdoba, Lilia L. Roa-Fuentes

“…This study evaluated aboveground biomass (AGB), species diversity, forest structure, and soil properties in SFs of the Colombian Amazon along a chronosequence, from early to mature successional stages, in landscapes of mountains and of hills to identify key indicators for effective restoration management. …”
Get full text

The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis by Zheng Liang, Dajin Pi, Jianwei Zhen, Haizhen Yan, Chuiyang Zheng, July Liang Chen, Wen Fan, Qingliang Song, Jinyue Pan, Dongdong Liu, Maoxing Pan, Qinhe Yang, Yupei Zhang

“…Nonalcoholic steatohepatitis (NASH) is the advanced stage of nonalcoholic fatty liver disease (NAFLD), which is distinguished by the accumulation of fat in the liver, damage to liver cells, and inflammation. …”
Get full text

MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis by Huifang Bai, Qianqian Dang, Guoliang Chen, Lingfeng Xie, Saining Wang, Ning Jiang, Xiaoxia Wu, Shuyan Zhang, Xuelin Wang

“…In conclusion, the study demonstrates that TJ-M2010-5 could effectively alleviate spleen impairment and reduce inflammation in mice infected with T. spiralis in its early stages by blocking the activation of PI3K/miR-136-5p/AKT3.…”
Get full text

Features of Professional Activity Reflection of the Olympiad “I Am a Professional” Participants by A. K. Belolutskaya, I. S. Krishtofik, V. A. Mkrtchyan

“…The study about the features of students’ professional reflection was carried out in 2021 during the period of the Olympiad “I am a professional” in the framework of three stages: planning/design, self-assessment/reflection, delayed group reflection. …”
Get full text

Biodiversity reporting: Comparing listed entities in the United Kingdom and South Africa by Dino Da Mata, Timothy Lai, Dusan Ecim, Warren Maroun, Dannielle Cerbone

“…In general, it is observed that biodiversity reporting is still in its nascent stage in both jurisdictions and offers limited insight into the understanding of biodiversity by organisations and their ability to incorporate direct and indirect impacts into their business models, risk assessment and strategy implementation. …”
Get full text

Acoustic Emission Simulation on Coal Specimen Subjected to Cyclic Loading by Huiqiang Duan, Depeng Ma

“…The damage and failure state of the loaded coal and rock masses is indirectly reflected by its acoustic emission (AE) characteristics. …”
Get full text

Sex and gender in perioperative cardiovascular research: protocol for a scoping review by Ana Sjaus, Nicole Fakhory

“…Methods Joanna Briggs Institute (JBI) methodology for scoping reviews will be followed in stages elaborated by Levac (2010). A comprehensive search strategy will be used to identify relevant primary research published since 2010. …”
Get full text

Psychometric Validation of the Hepatitis C Symptom and Impact Questionnaire (HCV-SIQv4) in a Diverse Sample of Adults with Chronic Hepatitis C Virus Infection Treated with an Inter... by Andrew Trigg, Eric Chan, Helen Kitchen, Tom Willgoss, Kai Fai Ho, Renee Pierson, Jane Scott

“…**Results:** Data from 437 patients were analyzed. Stage of liver disease was associated with symptom severity and functioning at baseline. …”
Get full text

Diversification outbreaks and dynamics of Asian leaf-litter frogs, genus Leptobrachella (Anura, Megophryidae), with the description of a new species from Guizhou Province, China by Tao Luo, Zi-Fa Zhao, Zhong-Lian Wang, Chang-Ting Lan, Ming-Yuan Xiao, Huai-Qing Deng, Ning Xiao, Jiang Zhou

“…Our results suggest a three-phase scenario for the diversification of Leptobrachella, with periods of acceleration and deceleration at every stage, a pattern consistent with the Indochina extrusion, the uplift of the Qinghai–Tibet Plateau and the intensification of the Asian monsoon since the Oligocene. …”
Get full text

Procedural Law of Ancient Rome in the Imperial Period by D. V. Slynko

“…The article examines the governing bodies of the Roman State, namely, the People’s Assembly, the king (rex) and the Senate. …”
Get full text

Indirect determination of FMDV 146S component concentration in non-inactivated suspension by comparison of graphs of the second derivative for real-time RT-PCR curves by M. I. Doronin, D. V. Mikhalishin, V. A. Starikov, D. A. Lozovoy, A. V. Borisov

“…Raw materials for vaccines at various stages of the technological process are tested for concentration of FMDV 146S component. …”
Get full text

Polycyclic Aromatic Hydrocarbons in Atmospheric PM2.5 during Winter Haze in Huang-gang, Central China: Characteristics, Sources and Health Risk Assessment by Mingming Shi, Tianpeng Hu, Yao Mao, Cheng Cheng, Weijie Liu, Qian Tian, Zhanle Chen, Xinli Xing, Shihua Qi

“…According to PM2.5 concentration and its changing trend, the haze can be divided into three stages: early (low concentration, January 13–15, EHZ), medium (high concentration, January 16–22, MHZ) and late (concentration decreased rapidly, January 23–24, LHZ). …”
Get full text