Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model by Youfeng Li, Yuning Zhang, Hua Wang, Chengfeng Sun, Dongmei Liu, Hongying Liu, Jia He, Furong Chen, Weiting Wang, Xi Jiang, Chu-tse Wu, Yuefeng Yang

“…Critical limb ischemia (CLI), an end-stage manifestation of peripheral artery disease (PAD), still lacks effective therapeutic strategies. …”
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Contribution of vitamin B 6 deficiency to anemia in children on regular hemodialysis by Fatma Atia, Hafez Bazaraa, Yara Abdelatty, Sarah Lotfy, Eman Eryan

“…Abstract Background Anemia is prevalent among pediatric patients diagnosed with end-stage kidney disease (ESKD). In addition, erythropoiesis-stimulating agents (ESA) and iron supplementation are considered the cornerstones in the management of anemia. …”
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Preoperative prediction of lymph node metastasis in intrahepatic cholangiocarcinoma: an integrative approach combining ultrasound-based radiomics and inflammation-related markers by Yu-ting Peng, Jin-shu Pang, Peng Lin, Jia-min Chen, Rong Wen, Chang-wen Liu, Zhi-yuan Wen, Yu-quan Wu, Jin-bo Peng, Lu Zhang, Hong Yang, Dong-yue Wen, Yun He

“…The combined model, which incorporates the optimal radiomics score, clinical N stage, and platelet-to-lymphocyte ratio (PLR), achieved an AUC of 0.882 in the validation cohort, significantly outperforming the clinical model with an AUC of 0.687 (P = 0.009). …”
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Efficient and accurate tobacco leaf maturity detection: an improved YOLOv10 model with DCNv3 and efficient local attention integration by Yi Shi, Hong Wang, Fei Wang, Yingkuan Wang, Jianjun Liu, Long Zhao, Hui Wang, Feng Zhang, Qiongmin Cheng, Shunhao Qing

“…Furthermore, the incorporation of the Efficient Local Attention (ELA) mechanism at multiple stages of the model has substantially enhanced the efficiency and fidelity of feature extraction. …”
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Experimental and Simulation Study on Reducing the Liquid Film and Improving the Performance of a Carbon-Neutral Methanol Engine by Yongzhi Li, Zhi Zhang, Haifeng Liu, Weide Chang, Zanqiao Shu, Hu Wang, Zunqing Zheng, Hua Zhao, Xinyan Wang, Mingfa Yao

“…As the EOI increases from 170 °CA to 360 °CA, the higher in-cylinder temperature and properly stratified mixture accelerate the early and middle stages of combustion, shorten the ignition delay, advance the center of combustion, and improve the brake thermal efficiency (BTE). …”
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Hospitalization outcomes in people living with HIV on Dolutegravir-based regimen in Mwanza, Tanzania: a comparative cohort by Godfrey A. Kisigo, Eric Barongo, Benson Issarow, Cody Cichowitz, Bahati Wajanga, Samuel Kalluvya, Robert N. Peck

“…Male sex, using DTG-based regimen for < 3 months, diagnosis of suspected IRIS, diagnosis of ART side effect, advanced WHO clinical stage, CD4 count < 200 cells/mm3, hemoglobin level 7–11.9 gm/dl and hemoglobin level < 7 gm/dl were all independent risk factors for death. …”
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A Full Computerized Workflow for Planning Surgically Assisted Rapid Palatal Expansion and Orthognathic Surgery in a Skeletal Class III Patient by Orazio Bennici, Alessia Malgioglio, Serena Moschitto, Gianrico Spagnuolo, Alberta Greco Lucchina, Vincenzo Ronsivalle, Gaetano Isola, Antonino Lo Giudice

“…In the present case report, we present and discuss the digital workflow involved in the orthodontic/orthognathic combined treatment of a skeletal malocclusion correction in a 17-year-old male patient affected by a skeletal class III, facial asymmetry, sagittal and transversal deficiency of the medium third of the skull, dental crowding, and bilateral cross-bite. The first stage of the treatment involved surgically assisted rapid palatal expansion and occlusal decompensation, using fixed self-ligating appliance. …”
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Hsp90 mutants with distinct defects provide novel insights into cochaperone regulation of the folding cycle. by Rebecca Mercier, Danielle Yama, Paul LaPointe, Jill L Johnson

“…In a simplified model, Hsp70 first helps load client onto Hsp90, ATP binding results in conformational changes in Hsp90 that result in the closed complex, and then less defined events result in nucleotide hydrolysis, client release and return to the open state. Cochaperones bind and assist Hsp90 during this process. …”
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A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim by Joseph Mort, Shipra Maheshwari, Nayanika Basu, Patrick Dillon, Kevin Brady, Harry Bear, Trish Millard

“…We present a 59-year-old female with left stage IIA (cT2N0M0) triple-negative breast cancer receiving neoadjuvant decitabine and pembrolizumab prior to neoadjuvant chemotherapy (NAC). …”
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LncRNA SNHG17 Contributes to Proliferation, Migration, and Poor Prognosis of Hepatocellular Carcinoma by Yue Luo, Junhao Lin, Jiakang Zhang, Zhenghui Song, Dayong Zheng, Fengsheng Chen, Xuefen Zhuang, Aimin Li, Xinhui Liu

“…Utilizing publicly available TCGA-LIHC, GSE102079 HCC datasets, and qRT-PCR, we found SNHG17 was significantly upregulated in HCC tissues and cell lines and was notably associated with larger tumor size, poorly differentiation, presence of vascular invasion, and advanced TNM stage. Furthermore, gain- and loss-of-function studies demonstrated that SNHG17 promoted cell proliferation and migration and inhibited apoptosis of HCC. …”
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Depression as a risk factor for osteoporosis independent of sarcopenia in hemodialysis patients: findings from a multicenter cross-sectional study by Xiaohua Hu, Xianwu Ye, Haimin Chen, Bibo Wu, Qi Guo, Chen Yu, Wei Ding, Jianying Niu, Junli Zhao, Hualin Qi, Suhua Zhang, Cheng Xue, Liming Zhang

“…Abstract Background Osteoporosis and sarcopenia frequently occur in patients with end-stage renal disease undergoing hemodialysis (HD), and depression is also a common mental health issue in this population. …”
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Autoantibodies in myasthenia gravis: cluster analysis and clinical correlations by Xupeng Sun, Meijie Qu, Xi Rong, Mingxing Lv, Yunbin Zhao, Yunjun Yan, Lin Liu, Na Sun, Hua Yue, Min Liu

“…As MG severity increased from types I to V, AChR+, RyR+, and titin+ proportions peaked at stage IIa. MuSK+ patients were relatively rare and mostly present in the subtype b group. …”
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One More Time about the Age of Teachers in Russian Universities: Old Problems and New Trends by V. F. Pugach

“…The paper presents results of analyzing age structure of Russian state universities teaching staff and its dynamics in the post-Soviet period. …”
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Effect of a closed-loop medication order executive system on safe medication administration at a tertiary hospital: a quasi-experimental study by Xuwen Yin, Haiyan Song, Jieyu Lu, Jing Yang, Rong Wang, Zheng Lin, Shudi Jiang, Hui Yuan, Xumei Wang, Dongmei Xu, Chunhong Gao, Yuan Zhou, Jiayi Xu, Chen Chen, Chenyu Gu, Qingqing Diao, Fang Li, Zejuan Gu

“…Root cause analysis and descriptive statistics were used to assess changes in types, stages, and causes of ME rates. The independent samples t -test was used to analyze secondary outcomes. …”
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AMERICA IN THE WORLD AFTER HEGEMONY by A. Y. Borisov

“…The author makes a comparative analysis between the dawn of the British Empire and current stage of crisis development of the United States with principal issue of transformation of the world order from unipolarity to multipolarity or from single power dominance to a more balanced international system. …”
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Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue by Sara Nava, Valeria Sordi, Luisa Pascucci, Carlo Tremolada, Emilio Ciusani, Offer Zeira, Moris Cadei, Gianni Soldati, Augusto Pessina, Eugenio Parati, Mark Slevin, Giulio Alessandri

“…Similarly, the addition of MFAT-CM recovered at early (3-7 days) and late stage (14-28 days) of culture strongly inhibited inflammatory function of U937 monocyte cell line, whereas the anti-inflammatory activity of LP-CM was drastically reduced after only 7 days of culture. …”
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Associations between contextual and compositional characteristics of early childcare facilities with health, health behaviours and well-being among young children aged 0 to 6 years... by Jennifer Hilger-Kolb, Sven Schneider, Raphael Herr, Nina Osenbruegge, Stephanie Hoffmann, Max Herke, Claudia Pischke, Leonie Sundmacher, Katharina Diehl

“…Introduction Early childhood is an important life stage which is crucial for determining health and health inequalities in later life. …”
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Влияние курсового приема L-орнитин- L-аспартата на фиброз и стеатоз печени у больных ассоциированной с нарушениями метаболизма жировой болезнью печени (неалкогольной жировой болезн... by Е. V. Garanina

“…Hyperammonaemia develops both in cirrhosis and earlier fibrotic stages during metabolic-associated fatty liver disease (MAFLD). …”
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Re-architecture for requirements of academic space development in the universities: design and validitation of RASD questionnaire by Zahra Karimian, Mahmoud Abolghasemi

“…Exploratory and confirmatory factor analysis were used to validate the questionnaire using SPSS 24 and Liseral 8.5 software. In qualitative stage, 67 codes, 4 concepts (formal, political, cultural, and scientific), and 14 components were extracted, which resulted in the word “Re-architecture” based on the acronym of the first letter. …”
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Scrapie-Responsive Gene 1 Promotes Chondrogenic Differentiation of Umbilical Cord Mesenchymal Stem Cells via Wnt5a by Yuchuan Zhou, Tian Zheng, Lin Li, Yangfang Guo, Jiayu Xiao, Jin Wang, Zhiqin Du, Hui Gao, Weiwei Tang, Liusan Yang, Haiyan Hu, Xiaodan Wang, Mingyao Meng, Zongliu Hou

“…However, MSC differentiation into chondroblasts or related cell lineages is elaborately controlled by stem cell differentiation stage factors and affected by an array of bioactive elements, which may impede the efficient production of target cells. …”
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