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  1. 281

    Blood Cell Profiles of the Tadpoles of the Dubois's Tree Frog, Polypedates teraiensis Dubois, 1986 (Anura: Rhacophoridae) by Madhusmita Das, Pravati Kumari Mahapatra

    Published 2012-01-01
    “…Population of erythrocytes was heterogeneous in population represented by various forms (oval, elliptical or rounded cells, comma shaped, teardrop shaped, schistocytes, senile erythrocytes, crenulated RBCs). Correlation between various morphometric values of erythrocytes was determined with different developing stages of tadpoles. …”
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  2. 282

    Changing patterns of social services for the elderly as innovative technologies for preserving social capital by R. M. Sadykov, N. L. Bolshakova

    Published 2024-11-01
    “…Due to age and health conditions, many older people are limited in their ability to leave home and perform daily tasks and functions. Senile problems represent negative changes that affect people’s lives and are associated with poor health. …”
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    Telomere Biology: Key to unlocking the fountain of youth…A Systematic Review. by Anirban Poddar, Anup Kumar Rana, Ranjita Santra, Phalguni Chakrabarti

    Published 2024-11-01
    “…Deterioration of physiological functions is typically associated with ageing process.This often manifests as various diseases which eventually creates a burden on health infrastructure.Telomere attrition is a phenomenon which involves shortening of telomeres with each cycle of cell division.The phenomenon of “Telomere Attrition” is a “Bi edged sword” as while being a protective shield for the genome on one hand, it also is the cause of many senility related degenerative disorders. As the role of telomere biology is well established in ageing,current research therefore aims to develop means to reduce telomere attrition,thereby reducing ageing & age related diseases.This review will focus on summarising the role of telomere biology in ageing & age related diseases while highlighting the recent advances in research aiming towards enhanced longevity & healthy ageing.This review will further emphasize on telomere targetted therapeutics such as telomerase activators & tankyrase inhibitors while also highlighting the role of antioxidative & antiinflammatory agents alongwith indirectly related approaches such as statins.…”
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  8. 288

    Therapeutic Actions of the Thiazolidinediones in Alzheimer’s Disease by María José Pérez, Rodrigo A. Quintanilla

    Published 2015-01-01
    “…In the AD brain is common to observe the accumulation of senile plaques formed by amyloid-beta (Aβ) peptide and the neurofibrillary tangles composed of modified tau protein, which both lead to cellular damage and progressive neurodegeneration. …”
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  9. 289

    Spines, Plasticity, and Cognition in Alzheimer's Model Mice by Tara Spires-Jones, Shira Knafo

    Published 2012-01-01
    “…The pathological hallmarks of Alzheimer's disease (AD)—widespread synaptic and neuronal loss and the pathological accumulation of amyloid-beta peptide (Aβ) in senile plaques, as well as hyperphosphorylated tau in neurofibrillary tangles—have been known for many decades, but the links between AD pathology and dementia and effective therapeutic strategies remain elusive. …”
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    Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence by Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li

    Published 2025-01-01
    “…Local intra-articular injection of FGF18 mRNA-LNP significantly alleviates OA symptoms in DMM and senile OA models. Sustained expression and accessibility of FGF18-mRNA to deeper chondrocytes makes LNP-mRNA more effective than FGF18 recombinant protein. …”
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    Evaluation of the Endothelial Cell Density and the Central Corneal Thickness in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma by Bożydar T. Tomaszewski, Renata Zalewska, Zofia Mariak

    Published 2014-01-01
    “…Evaluation of central corneal thickness (CCT) and endothelial cell density (ECD) in patients with senile cataract and coexisting pseudoexfoliation (PEX) syndrome with glaucoma (PEXG) and without glaucoma using specular microscopy. …”
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  14. 294

    Effects of Gyroscope on Arm Swing and Gait in Healthy Volunteers by Meriç Selim Şipal, Elif Yalçın, Aynur Ayşe Karaduman

    Published 2023-01-01
    “…In the future, a medical device that has the features of a gyroscope can be designed for its use in the treatment of Parkinson’s disease and Senile Bradykinesia.…”
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  15. 295

    Lymphatic platelet thrombosis limits bone repair by precluding lymphatic transporting DAMPs by Yangkang Zheng, Lin Cong, Li Zhao, Pengyu Wang, Lianping Xing, Junling Liu, Hao Xu, Ning Li, Yongjian Zhao, Luying Yuan, Qi Shi, Xueqing Sun, Qianqian Liang, YongJun Wang

    Published 2025-01-01
    “…Lymphatic platelet thrombolysis also benefits senile fracture healing in female mice. These findings demonstrate that LPT limits bone regeneration by impeding lymphatic transporting DAMPs. …”
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  16. 296

    Endothelial Cell Loss after Phacoemulsification according to Different Anterior Chamber Depths by Hyung Bin Hwang, Byul Lyu, Hye Bin Yim, Na Young Lee

    Published 2015-01-01
    “…We conducted a prospective study on 135 eyes with senile cataracts. Eyes with nuclear density grades of 2 to 4 were divided into three groups according to ACD: ACD I, 1.5 < ACD ≤ 2.5 mm; ACD II, 2.5 < ACD ≤ 3.5 mm; or ACD III, 3.5 < ACD ≤ 4.5 mm. …”
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    Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer’s Disease Mutations by Alejandro Soto-Ospina, Pedronel Araque Marín, Gabriel de Jesús Bedoya, Andrés Villegas Lanau

    Published 2021-01-01
    “…Alzheimer’s disease manifests itself in brain tissue by neuronal death, due to aggregation of β-amyloid, produced by senile plaques, and hyperphosphorylation of the tau protein, which produces neurofibrillary tangles. …”
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