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  1. 43761
  2. 43762

    Mechanism of Qingjie Fuzheng Granules on alleviating 5-FU chemotherapy-induced intestinal mucositis in a mouse model of Colorectal Cancer by regulating Cathepsin B/NLRP3 pathway by Yuan Yingfei, Lin Jiumao, Lin Minghe, Zhao Jinyan, Chen Xuzheng, Liu Jinhong, Zhu Xiaoqin

    Published 2024-01-01
    “…After the last administration of the drug on the seventh day, the mice were fasted for 12 h, then, animal samples of mice were collected for experimental detection. …”
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  3. 43763

    Implementation strategies: lessons learned during an e-learning intervention to improve dietary behaviors and feeding practices in early childhood education and care by Henrik Lian, Nina Cecilie Øverby, Frøydis Nordgård Vik, Anine Christine Medin, Natalie Garzon Osorio, Christine Helle, Tormod Bjørkkjær, Penelope Love, Harry Rutter, Mary Elizabeth Barker, Elisabet Rudjord Hillesund, Sissel Heidi Helland

    Published 2025-01-01
    “…Brief (5–7 min minutes), semi-structured phone interviews, covering key points, were conducted with the champions 8 times, evenly distributed over six months. The interviews were analysed using qualitative thematic analysis. …”
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  4. 43764

    Effect of Exercise Preconditioning on Autophagy and Apoptosis of Cardiomyocytes in Aged Rats with Myocardial Ischemia Reperfusion Injury by LI Hongyu, YIN Xia, WANG Yanxia, Li Yuting, ZHU Luwen, TANG Qiang

    Published 2022-04-01
    “…The Con group and the IR group did not receive special exercise intervention, the EP+IPC group, the EP+IPC+saline group and the EP+IPC+3-MA group received exercise preconditioning intervention (gradient exercise training was performed on an electric animal experimental treadmill, one time a day, five days a week, continuous training for six weeks). …”
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  5. 43765

    Propolis mouthwashes efficacy in managing gingivitis and periodontitis: a systematic review of the latest findings by Muhammed Al-Huda Ballouk, Mohamed Altinawi, Abeer Al-Kafri, Talar S. Zeitounlouian, Piotr S. Fudalej

    Published 2025-01-01
    “…The focus was on clinical randomized controlled trials (RCTs) that examined the effectiveness of propolis-containing mouthwashes in comparison with propolis-free ones for the treatment of gingivitis and periodontitis, employing related periodontal indices. Animal studies, microbiological studies, in-vitro studies, retrospective studies, case-control studies, cohorts, case reports, case series, reviews, letters, editorials, meta-analyses, and non-clinical randomized controlled trials (non-RCTs), all were excluded. …”
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  6. 43766

    Effect of Ginkgolide B on Non-Alcoholic Fatty Liver Disease based on Notch Signaling Pathway by Hong YU, Junzi WU, Bo SONG, Jun LI

    Published 2021-04-01
    “…The normal group were fed with normal fodder for 12 weeks, and the experiment group were fed with high-fat and high-sugar fodder (83.25%basic feed, 10%lard, 5%sucrose, 1.5%cholesterol and 0.25%sodium cholate) for 12 weeks to construct NAFLD animal model (The success criterion for modeling is that: there are a large number of fat vacuoles in the liver). …”
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  7. 43767

    SEED (Stoke Disease Early Detection Application) - Rancang Bangun Aplikasi Mobile Berbasis Android untuk Mendiagnosis Gejala Dini Penyakit Stroke Menggunakan K-Nearest Neighbor (K-... by Dedin Anike Putra, Muhammad Dimas Setiawan Sanapiah, Azifatul Istna Hanifah, Tri Afirianto

    Published 2019-05-01
    “…Pada zaman modern, stroke tidak hanya menyerang orang yang sudah lanjut usia namun juga bisa menyerang orang usia muda. Data dari Rumah Sakit Saiful Anwar (RSSA) Kota Malang, sepanjang tahun 2016 penderita penyakit stroke 30% nya masih diusia muda, yaitu antara usia 18 – 40 tahun. …”
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  8. 43768
  9. 43769
  10. 43770

    Effect of Electroacupuncture Preconditioning on Inflammatory Factors of Rabbits after Spinal Cord Ischemia-Reperfusion Injury by Mengli YAO, Xianghua CHEN, Zhaohui CHEN, Hai WANG

    Published 2020-12-01
    “…Objective:To observe the effects of electroacupuncture preconditioning on the pathological changes of spinal cord tissue and the expression of inflammatory cytokines such as interleukin-1β(IL-1β), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α), interleukin-1 receptor antagonist(IL-1Rα)after spinal cord ischemia-reperfusion injury, and to explore the protective mechanism of electroacupuncture on spinal cord ischemia-reperfusion injury in rabbits.Methods:A total of twenty-four New Zealand white rabbits were randomly divided into the sham operation group, the model group and the electroacupuncture group according to the random number table method, with eight cases in each group.The model was made by Zivin method in the model group and the electroacupuncture group, the abdominal cavity was opened after intravenous anesthesia at ear margin, the abdominal aorta was exposed and temporarily clamped, and the rabbit model of spinal cord ischemia-reperfusion injury was established after ischemia for thirty minutes.The model preparation and experimental animal treatment of the sham operation group were the same as those of the model group, however, the dissection was fully exposed without clamping the abdominal aorta.At thirty minutes before the induction of rabbit spinal cord ischemia-reperfusion model, SDZ-II electroacupuncture instrument was used to acupuncture bilateral"Xuanzhong"and"Yanglingquan"acupoints in the electroacupuncture group, intervention for thirty minutes.All rabbits were killed after intervention for twelve hours, and the L2-5 segments of spinal cord tissue were captured.HE staining method was used to observe the pathological changes of spinal cord tissues in the three groups; Immunohistochemical method was used to observe the localization and content changes of IL-1β, IL-6 and TNF-α; Enzyme-linked immunosorbent assay(ELISA)was used to detect the contents of IL-1β, IL-6, TNF-α and IL-1Rα in serum before modeling and 4, 8, 12 hours after ischemia-reperfusion.Results:①HE staining results: compared with the sham operation group, the number of neurons in spinal cord tissue in the model group decreased, the color of nucleus and cytoplasm of cells became lighter, and the boundary of nuclear membrane was not clear.In severe cases, the nucleus dissolved or even nucleolus disappeared, there were transparent areas around cells, and axons showed different degrees of degeneration such as enlargement, swelling and disappearance; compared with the model group, the number of neurons in the electroacupuncture group increased, the structure of most neurons was clear, the atrophy degree of nucleolus and nucleus was light, only a small amount of cells became deformed and necrosis, the damage degree of cells were lighter, and the density of surviving neurons increased.②Immunohistochemistry results: compared with the sham operation group, the expressions of IL-1β, IL-6 and TNF-α of spinal cord tissue in the model group were significantly increased(<italic>P</italic>&lt;0.05);compared with the model group, the contents of IL-1β, IL-6 and TNF-α in the spinal cord of rabbits in the electroacupuncture group were significantly decreased(<italic>P</italic>&lt;0.05).③ELISA results: Before modeling, there was no significant difference in the three groups(<italic>P</italic>&gt;0.05);compared with before modeling, the expressions of IL-1β, IL-6, TNF-α, IL-1Rα in serum of the three groups increased in different degrees at 4, 8 and 12 h after ischemia-reperfusion, with significantly significance(<italic>P</italic>&lt;0.05);compared with the sham operation group at the same time, the expressions of IL-1β, IL-6, TNF-α and IL-1Rα in the model group increased significantly at 4, 8 and 12 h after reperfusion(<italic>P</italic>&lt;0.05);compared with the model group at the same time, the expression of IL-1β and TNF-α in the electroacupuncture group decreased significantly at 4, 8, 12 h after reperfusion(<italic>P</italic>&lt;0.05).Conclusion:Electroacupuncture pretreatment can effectively alleviate the pathological injury of spinal cord and has a good protective effect on spinal cord ischemia-reperfusion injury, which may be related to inhibit the expression of IL-1β, IL-6 and TNF-α and promote the expression of IL-1Rα.…”
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  11. 43771
  12. 43772

    L’enterrement d’une triade divine féminine à Lugdunum : étude du dépôt de la place d’Albon à Lyon (Métropole de Lyon) by Lucas Guillaud, Emmanuel Bernot, Aline Colombier-Gougouzian, Amaury Gilles, Nicolas Garnier

    Published 2024-12-01
    “…It belongs to a period in the 3rd century when numerous “treasures” or “deposits” were discovered. However, unlike the large finds of Dury, Bavay, Neupotz or Hagenbach, the Lyon find is very homogeneous. …”
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  13. 43773

    CYTOKINES AND PROTEINS OF THE EXTRACELLULAR MATRIX IN THE BLOOD OF RATS OF DIFFERENT AGES AFTER FILLING THE DEFECT IN THE FEMORAL METAPHYSIS WITH ALLOGENEIC BONE IMPLANTS SATURATED... by Petro Vorontsov, Frida Leontieva, Vladyslav Tulyakov, Igor Husakov

    Published 2023-10-01
    “…In 12-month-old rats in comparison with 3-month-old animals we noted more active inflammation, with a slowed activity in bone remodeling.…”
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  14. 43774

    Efek Lama Penyimpanan Asi Terhadap Kadar Protein dan Lemak yang Terkandung Didalam ASI by Indri Putri Sari, Ariadi ., Ety Yerizel

    Published 2016-01-01
    “…Ini merupakan <em>true experiment</em> dengan pendekatan <em>pretest-post test control group design</em>. …”
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  15. 43775

    Mechanism of DMOC in Diabetes Mellitus with Liver Fibrosis by Zizhi XIAO, Hong SHI, Huanwen RAO, Lifen LUO

    Published 2019-04-01
    “…DMOC intervention was conducted in the control group and the control intervention group at the 36th-44th week and animal samples were taken in all groups at the 44th week. …”
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  16. 43776
  17. 43777
  18. 43778

    Effect of Acupuncture on the Expression of Heme Oxygenase 1 and Inflammatory Factors in Rats with Intracerebral Hemorrhage by CHEN Qiuxin, KONG Ying, YU Tingting, ZHANG Yu, LIU Peng, ZHANG Xin

    Published 2021-10-01
    “…The Berderson scoring method was used to determine the animal success model, and rats with a score of 1-3 were included in the experiment. …”
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  19. 43779
  20. 43780

    Call for Papers: How attractive are political parties and trade unions to young people? by IF and FRFG

    Published 2018-06-01
    “…In other countries, hardly any of these problems seem to exist. According to 2017 figures from the United Kingdom, the share of members aged 18-24 reflects the general population of 8.9% quite well: group size estimates suggest that 18-24s make up 14.4% of the Green Party, 13.2% of the Conservative Party and 11.5% of the Labour Party, with only the Scottish National Party and UK Independence Party (UKIP) below the 8.9%, at 6.9% and 6.7% respectively (UK Party Members Project; https://esrcpartymembersproject.org). …”
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