From Ca2+ dysregulation to heart failure: β-adrenoceptor activation by RKIP postpones molecular damages and subsequent cardiac dysfunction in mice carrying mutant PLNR9C by correct... by Theresa Brand, Bettina Tanitha Baumgarten, Sabrina Denzinger, Yvonne Reinders, Miriam Kleindl, Constanze Schanbacher, Florian Funk, Nilgün Gedik, Mahmood Jabbasseh, Petra Kleinbongard, Jan Dudek, Julia Szendroedi, Elen Tolstik, Kai Schuh, Martina Krüger, Dobromir Dobrev, Friederike Cuello, Albert Sickmann, Joachim P. Schmitt, Kristina Lorenz

Get full text

Whole genomic analysis uncovers high genetic diversity of rifampicin-resistant Mycobacterium tuberculosis strains in Botswana by Tuelo Mogashoa, Tuelo Mogashoa, Johannes Loubser, Ontlametse T. Choga, Ontlametse T. Choga, Justice Tresor Ngom, Wonderful T. Choga, Wonderful T. Choga, Mpaphi B. Mbulawa, Tuduetso Molefi, One Stephen, Topo Makhondo, Kedumetse Seru, Patience Motshosi, Boitumelo Zuze, Joseph Makhema, Rosemary M. Musonda, Dimpho Otukile, Chawangwa Modongo, Botshelo T. Kgwaadira, Keabetswe Fane, Simani Gaseitsiwe, Rob M. Warren, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Anzaan Dippenaar, Elizabeth M. Streicher

Get full text

The Knee-SCHOOL: a brief patient-centered multidisciplinary educational program for knee osteoarthritis by Denise Vianna Machado Ayres, Sabrina Saemy Tome Uchiyama, Andréa Oliveira Prates, Rosana Aparecida Freitas Lopes, Antenor Bispo Santos Silva, Denise Rodrigues Tsukimoto, Rosimeire Alves Amorim, Taynah Souza Ribeiro, Artur Cesar Aquino Santos, André Tadeu Sugawara, André Tadeu Sugawara, Marcos Montagnini, Linamara Rizzo Battistella, Linamara Rizzo Battistella, Marta Imamura, Marta Imamura

“…All participants received the program well, with no drop-out rates or reported adverse events.ConclusionThe Knee-SCHOOL utilized a multidisciplinary educational approach and an exercise practice addressing multiple aspects of KOA pain. …”
Get full text

Editorial by Ann-Kristin Kölln, Antony Mason, Maria Lenk, Jörg Tremmel, Markus Rutsche

“… Among the many headlines that followed the 2018 midterm elections in the United States, one stood out as very good news for political representation: the election of Alexandria Ocasio-Cortez. …”
Get full text

Global glucose metabolism rate as diagnostic marker for disorder of consciousness of patients: quantitative FDG-PET study by Dongsheng Liu, Dongsheng Liu, Dongsheng Liu, Nan Wang, Nan Wang, Nan Wang, Ming Song, Ming Song, Ming Song, Xiaoke Chai, Xiaoke Chai, Qiheng He, Tianqing Cao, Dawei Kong, Zhuhuan Song, Guangming Zhang, Lei Liu, Xiaosong Wang, Guoqiang Chen, Shaoya Yin, Shaoya Yin, Shaoya Yin, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Jizong Zhao, Jizong Zhao

“…The normalization procedure utilized a customized template following the methodology outlined by Phillips et al. …”
Get full text

COVID-19 vaccination and cerebral small vessel disease progression—A prospective cohort study by Yiu Ming Bonaventure Ip, Sangqi Pang, Alan Yao, Lucas Lau, Anki Miu, Katarina Chiu, Ho Ko, Andrew Kwok, Helen Y Chan, Sharon Lee, Howard Chan, Trista Hung, Bonnie Lam, Vincent Hui, Haipeng Li, Lin Shi, Jill Abrigo, Xinyi Leng, Yannie Soo, Sze Ho Ma, Vincent CT Mok, Hugh S Markus, Chris Mok, David SC Hui, Thomas W Leung

“…The primary outcome was progression of a composite of six standard cSVD biomarkers. We compared the risk of cSVD progression between vaccinated and unvaccinated subjects and identified predictors of primary outcome within each vaccine subgroup. …”
Get full text

Epidemiology and Ecology of Toscana Virus Infection and Its Global Risk Distribution by Xue-Geng Hong, Mei-Qi Zhang, Fang Tang, Si-Hui Song, Jia-Yi Wang, Zhen-Yu Hu, Li-Ming Liu, Xiao-Ai Zhang, Yi Sun, Li-Qun Fang, Wei Liu

“…We further predicted the global distribution of the two sandfly vectors, based on which the global risk of TOSV was projected, after incorporating the environmental, ecoclimatic, biological, and socioeconomic factors. A total of 1342 unique studies were retrieved, among which 389 met the selection criteria and were included for data extraction. …”
Get full text

OVERCOMING THE ANTINOMIES OF HUMAN EXISTENCE: ONTOLOGY OF TRICKSTER by T. V. Danylova

“…“Panchatantra” is deeply rooted in the animal epos, which is based on the totemic myth. Myths were created by primitive thinking that sought to systematize the world, to give it order through binary oppositions. …”
Get full text

Effect of Three Colostrum Diets on Passive Transfer of Immunity and Preweaning Health in Calves on a California Dairy following Colostrum Management Training by Deniece R. Williams, Patrick Pithua, Angel Garcia, John Champagne, Deborah M. Haines, Sharif S. Aly

Get full text

A versatile platform based on matrix metalloproteinase-sensitive peptides for novel diagnostic and therapeutic strategies in arthritis by Mingyang Li, Tao Deng, Quan Chen, Shenghu Jiang, Hang Li, Jiayi Li, Shenglan You, Hui-qi Xie, Bin Shen

Get full text

Effects of filleting methods on composition, gelling properties and aroma profile of grass carp surimi by Liu Shi, Tao Yin, Qilin Huang, Juan You, Yang Hu, Dan Jia, Shanbai Xiong

Get full text

A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications by Mahnoor, Khafsa Malik, Abeer Kazmi, Tahira Sultana, Naveed Iqbal Raja, Yamin Bibi, Mazhar Abbas, Irfan Anjum Badruddin, M. Mahmood Ali, Muhammad Nasir Bashir

“…The importance of nanocomposites constantly attains attention because of their unique properties all across the fields especially in medical perspectives. …”
Get full text

Unlocking the Potential of Buckwheat Hulls, Sprouts, and Extracts: Innovative Food Product Development, Bioactive Compounds, and Health Benefits – a Review by Zhibek Atambayeva, Almagul Nurgazezova, Kumarbek Amirkhanov, Zhanna Assirzhanova, Altyngul Khaimuldinova, Haykuhi Charchoghlyan, Meruyert Kaygusuz

“…The review underscores the need for further research to optimize the use of buckwheat less-utilized parts and to better understand their health impacts. …”
Get full text

Rauwolfia vomitoria- a promising medical plant for benign prostatic hyperplasia management; yet with challenges by George Awuku Asare, Perpetua Dagadu, Samuel Adjei, Bernice Asiedu, Samkeliso Takaidza, Vivash Naidoo, Brodrick Amoah, Ifeoma Celestina Orabueze, Kwasi Bugyei

“…This study aims to investigate the therapeutic effects of Rauwolfia vomitoria Aqueous Root Extract (RVARE) as a potential natural oral treatment for BPH. Methodology: Six groups of male Sprague-Dawley rats were established [N = 7/group]. …”
Get full text

A hybrid Prairie INFO fission naked algorithm with stagnation mechanism for the parametric estimation of solar photovoltaic systems by Pankaj Sharma, Rohit Salgotra, Saravanakumar Raju, Mohamed Abouhawwash, S. S. Askar

Get full text

Hybrid Approach in the Analysis of Bovine Milk Protein Hydrolysates as a Source of Peptides Containing Di- and Tripeptide Bitterness Indicators by Anna Iwaniak, Piotr Minkiewicz, Monika Hrynkiewicz, Justyna Bucholska, Małgorzata Darewicz

Get full text

Soybean Lectin Enhances Biofilm Formation by Bradyrhizobium japonicum in the Absence of Plants by Julieta Pérez-Giménez, Elías J. Mongiardini, M. Julia Althabegoiti, Julieta Covelli, J. Ignacio Quelas, Silvina L. López-García, Aníbal R. Lodeiro

Get full text

Comparison of the somatic growth of juvenile sea urchin Paracentrotus lividus (Lamarck, 1816) fed with experimental and commercial pre-growth diets by Noelia Tourón Besada, Estefanía Paredes, Damián Costas

“…En este estudio se midió el aumento de tamaño y peso de juveniles de P. lividus alimentados con 4 dietas diseñadas específicamente, 2 dietas comerciales y un control basado en la macroalga parda Laminaria sp. …”
Get full text

Comparative experimental anesthesia efficacy study of epidural injection at the sacrococcygeal space using ultrasound guidance versus blindness technique in Egyptian donkeys (Equus... by Mohamed A. Hamed, Hazem Hamouda, Mohammed Elmetwally, Foad Farrag, Mohamed Abdo Rizk, Mohamed M. A. Abumandour, Yamen Mohammed Hegazy, Alaa Samy

Get full text

Insecticide chlorfenapyr confers induced toxicity in human cells through mitochondria-dependent pathways of apoptosis by Longfei Wang, Zheng Qu, Yifan Xu, Guangqing Yu, Xiangyang Liu, Meizi Wang, Shiheng An, Xinming Yin, Risong Na, Youwu Hao

Get full text