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42241
Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review
Published 2025-02-01“…However, cyclophosphamide has been employed in developing animal models of interstitial cystitis in in vivo studies. …”
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42242
Long-term smoking contributes to aging frailty and inflammatory response
Published 2025-01-01“…Additionally, we used the GEO database to validate the correlation between frailty and inflammation in elderly smokers, facilitating cross-comparisons between animal model findings and human sample data. Our results show that mice exposed to high-dose smoking were significantly more prone to frailty, with notable reductions in maximal grip strength (p < 0.01) and drop time (p < 0.001). …”
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42243
Isolation and study of biological properties of <i>Bordetella bronchiseptica</i>-specific bacteriophages
Published 2022-09-01“…Three new bacteriophages were recovered from clinical material of animals with respiratory disease signs: vB_BbrS_2/200220.7.2, vB_BbrS_4/200220.7.1, vB_BbrM_5/200220.7.2. …”
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42244
Human Umbilical Cord Perivascular Cells Prevent Tumor Growth in a Melanoma Tumor-Bearing Mouse Model and Modulate Breast Cancer and Melanoma Cells in a Cell Line-Dependent Manner I...
Published 2023-01-01“…Systemic administration of FTM and term human umbilical cord perivascular cells, but not fibroblast cells, prevented melanoma tumor growth in a tumor-bearing animal model by modulating tumor cell proliferation and systemic inflammatory mechanisms. …”
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42245
Estimating the Effect of Adhering to the Recommendations of the 2019 Canada’s Food Guide on Health Outcomes in Older Adults: Protocol for a Target Trial Emulation
Published 2025-01-01“…In the hypothetical trial, participants will be instructed to meet sex-specific minimal intakes for vegetables and fruits, whole grains, animal- and plant-based protein foods, milk and plant-based beverages, and unsaturated fats. …”
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42246
Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization
Published 2025-02-01“…The efficacy of the vaccine was assessed in a therapeutic animal model of HPV-induced cancer. Results Our study revealed that the final construct was successfully expressed in E. coli BL21 (DE3)-gold within 4 h of induction as inclusion bodies. …”
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42247
High-altitude hypoxia aggravated neurological deficits in mice induced by traumatic brain injury via BACH1 mediating astrocytic ferroptosis
Published 2025-02-01“…In order to deeply investigate this scientific issue, we constructed a high-altitude hypoxic TBI model at different altitudes and used animal behavioral assessments (Modified neurological severity score, rotarod test, elevated plus maze test) as well as histopathological analyses (brain gross specimens, brain water content, Evans blue content, hypoxia inducible factor-1α, Hematoxylin-Eosin staining and ROS detection) to reveal its underlying principles and characteristics. …”
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42248
Black Soldier Fly (<I>Hermetia illucens</I>) Oil Inclusion and its Effects on Growth Performances in Common Carp (<I>Cyprinus carpio</I>)
Published 2023-07-01“…Fish growth can be increased by adding nutrients in the form of animal oil sources. An alternative ingredient that can be used to support fish growth with good nutritional content and relatively inexpensive is maggot oil or black soldier fly (H. illucens) oil. …”
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42249
Body size prediction in scorpions: a phylogenetic comparative examination of linear measurements of individual body parts
Published 2025-01-01“…Overall, accurate predictions of total length and carapace length could be achieved using any of the studied traits as single predictors. …”
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42250
Managing ADHD Symptoms in Children Through the Use of Various Technology-Driven Serious Games: A Systematic Review
Published 2025-01-01“…They need help to retain the directions given by teachers and are very animated. Focus issues, hyperactivity, and attention problems may hamper learning. …”
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42251
Cowpea cropping systems, traits preference and production constraints in the upper west region of Ghana: farmers' consultation and implications for breeding
Published 2023-06-01“…Walp) is used primarily as food for humans and feed for animals. It is also used for soil management within a cropping system. …”
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42252
Analysis of the circadian rhythm of biological processes in mouse liver and kidney
Published 2018-01-01“…The greatest number of rhythmic genes in the liver has an increased level of translation at the beginning of the dark phase of the day corresponding to increased animal activity. In the kidneys, the differences in the distribution of the number of genes in the phase of an elevated translation level by the time of day were less pronounced, and the maximum number of such genes was observed from the middle of the light phase of the day to the middle of the dark one. …”
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42253
Immunization with a Synthetic Helicobacter pylori Peptide Induces Secretory IgA Antibodies and Protects Mice against Infection
Published 2019-01-01“…In addition, levels of serum TH1 and TH2 cytokines were not altered after immunization, except for the significant increase in IL-6 production in immunized and/or infected animals. Moreover, immunization correlated with plasma secretory IgA and IgG, whereas infection alone only elicited IgM antibodies. …”
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42254
Particulate matter concentrations and health risks associated with cow hides singeing in Abattoirs in Benin City, Nigeria
Published 2024-12-01“… Introduction: The singeing of animals is one of the major sources of human exposure to air pollutants in abattoirs especially in developing countries and it can cause various adverse health effects among the workers. …”
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42255
The Supernatant of Tonsil-Derived Mesenchymal Stem Cell Has Antiallergic Effects in Allergic Rhinitis Mouse Model
Published 2020-01-01“…We identified the increment of TGF-β1, PGE2, and HGF in the T-MSCs-CM. In an animal study, the T-MSCs-CM-treated group showed significantly reduced allergic symptoms and infiltration of eosinophils and neutrophils in the nasal mucosa, whereas there was no significant difference in total IgE and the OVA-specific IgE level. …”
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42256
Thermal ablation enhances immunotherapeutic effect of IP-001 on orthotopic liver cancer in a rat model
Published 2024-12-01“…When tumor size reached 1.0–1.5 cm3, the animals were divided randomly into 4 groups, (1) MWA+IP-001; (2) MWA+saline; (3) sham MWA+IP-001 and (4) sham MWA+saline (n = 5 each group).Results IP001 + MWA treatment significantly suppressed tumor growth in comparison to the other 3 groups. …”
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42257
Mycobacterium bovis BCG Surface Antigens Expressed under the Granuloma-Like Conditions as Potential Inducers of the Protective Immunity
Published 2019-01-01“…The worldwide incidence of bTB is in rise, creating potential reservoir and increased infection risk for humans and animals. In attempts to identify novel surface antigens of Mycobacterium bovis as a proof-of-concept for potential inducers of protective immunity, we investigated surface proteome of M. bovis BCG strain that was cultured under the granuloma-like condition. …”
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42258
Comparative study of packaging materials developed from fish and legume protein concentrates
Published 2025-06-01“…The results of the study show the utilization of food industry potential waste for producing environmentally friendly packaging materials.…”
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42259
Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity
Published 2023-01-01“…In contrast, extrahepatic inflammation, antigen-specific immunity, and antitumor activity remained unaffected in Ter119 treated animals.Conclusions Our study offers a targeted approach to uncouple CD40-augmented antitumor immunity in peripheral tissues from harmful inflammatoxicity in the liver.…”
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42260
Clinical, histopathological and parasitological follow-up of dogs naturally infected by Leishmania infantum before and after miltefosine treatment and associated therapies.
Published 2025-01-01“…The clinical conditions of the infected animals were improved and the skin parasite load decreased after treatment, even when distinct combination therapies were performed. …”
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