Conditioned Medium from Human Amnion-Derived Mesenchymal Stem Cells Regulates Activation of Primary Hepatic Stellate Cells by Qingjie Fu, Shunsuke Ohnishi, Naoya Sakamoto

“…Human amnion-derived mesenchymal stem cell (hAMSC) transplantation has been reported to ameliorate liver fibrosis in animal models. However, the mechanism for the prevention of liver fibrosis is poorly understood. …”
Get full text

BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework by Miles Anderson-Watters, Ilyas M. Khan

“…Collagen remodelling during maturation is difficult to study because it spans a period of time between birth and puberty, and in larger animals this can be months or years. In this study, we show that growth factor bone morphogenetic protein-9 (BMP9) induces collagen remodelling in intact immature articular cartilage explants within 21 days, generating the characteristic arcade-like structure and zonal anisotropic architecture of adult cartilage. …”
Get full text

Alpha synuclein overexpression can drive microbiome dysbiosis in mice by Timothy R. Sampson, Zachary D Wallen, Woong-Jai Won, David G. Standaert, Haydeh Payami, Ashley S. Harms

“…Abstract Growing evidence indicates that persons with Parkinson disease (PD), have a unique composition of indigenous gut microbes. Given the long prodromal or pre-diagnosed period, longitudinal studies of the human and rodent gut microbiome before symptomatic onset and for the duration of the disease are currently lacking. …”
Get full text

Trypsin inhibitor activity in representatives of the genus Hedysarum (Fabaceae): the polyvariance of seasonal dynamics in Southern Siberia by E. V. Zhmud, N. S. Zinner, O. V. Dorogina

“…In view of these findings, these two species may be recommended for practical utilization in this phase of seasonal development.…”
Get full text

Food Safety Practice and Its Associated Factors among Meat Handlers in North Shewa Zone, Oromia, Ethiopia by Samuel Chane Teferi

“…The majority of foodborne diseases arise from foods of animal origin. Hence, this study was proposed to evaluate meat handling practices and associated factors working in butcher shops in North Shewa Zone. …”
Get full text

Comparison of the Influence of Vegetarian and Mediterranean Diets on the Formation of Kidney Stones by Sebastian Samuła, Michał Mazur, Dorota Waz, Jakub Szarłowicz, Zofia Goliszek, Karolina Łucja Sobek, Wiktoria Tabin-Barczak, Aldona Sokołowska, Klaudia Fikas, Kamil Chwaliszewski

“…Results: The vegetarian diet, rich in citrate, magnesium, and potassium, demonstrates urine-alkalizing properties that counteract kidney stone formation. …”
Get full text

Molecular investigation of feline herpesvirus 1 (fhv-1) and feline calicivirus in cats with respiratory system problem by Seval Bilge Dağalp, Fırat Doğan, Touraj Aligholipour Farzani, Ali Rıza Babaoğlu, Gülizar Acar Kırmızı, Mehmet Çabalar

“…<p> <b>Conclusion:</b> These infections, as well as being seen in infected cats, can also be detected in healthy-looking animals and it should be noted that this should not be ignored in the transmission of these infections. …”
Get full text

Enhanced silk production and pupal weight in Bombyx mori through CRISPR/Cas9-mediated circadian Clock gene disruption. by Daniel J Brady, Alessio Saviane, Matteo Battistolli, Irene Varponi, Federica Barca, Kunihiro Shiomi, Silvia Cappellozza, Federica Sandrelli

“…Beyond traditional silk production, the growing demand for insect larvae in cosmetics, biomedical products, and animal feed underscores the need to enhance B. mori productivity. …”
Get full text

Preclinical evaluation of the potential PARP-imaging probe [carbonyl-11C]DPQ by Katarína Benčurová, Theresa Balber, Victoria Weissenböck, Lukas Kogler, Joachim Friske, Verena Pichler, Markus Mitterhauser, Marcus Hacker, Cécile Philippe, Marius Ozenil

“…Conclusions Although [carbonyl-11C]DPQ demonstrated metabolic stability and specific binding in vitro, suboptimal tumour-targeting properties and pronounced liver metabolism were observed in ovo. Therefore, further animal experiments with mammalian models were not indicated.…”
Get full text

Urine metabolic profile in rats with arterial hypertension of different genesis by A. A. Sorokoumova, A. A. Seryapina, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, М. А. Gilinsky, А. L. Markel

Subjects: Get full text

Toxicopathological Effects of the Venom of Echis ocellatus on Experimentally Envenomated Swiss Albino Rats by P. O. Yusuf, D. Ada, D. B. Nuhu, S. Dahiru, P. M. Ameh, M. Mamman, M. U. Kawu, M. Bisallah, S. J. Enam

“…The significance of Echis ocellatus in causing envenomation in humans and animals in Northern Nigeria has been widely recognized, with experts identifying it as the most medically important snake in the region. …”
Get full text

Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…An important cytotoxic impact of amyloidogenic prefibrillar LC oligomers on cardiomyocytes is by now established in isolated rodent cardiomyocytes, simple animal models, or cardiomyocyte-like cell lines. However, the response of human cardiomyocytes to this pathogenic condition is currently unknown. …”
Get full text

Ethnoécologie et primatologie des grands singes, quand deux disciplines se nourrissent l'une l'autre by Richard Dumez

“…Nous verrons que les travaux ethnozoologiques et ethnoéthologiques sur les grands singes apparaissent, d'une part, comme des outils utiles pour apporter de premiers éclairages sur ces animaux difficilement observables par les scientifiques, si ce n'est à l'issue d'un long processus d'habituation, et que, d'autre part, la proximité biologique entre hommes et grands singes, font des discours des premiers sur les seconds un prisme original pour interroger la relation entre des sociétés et leur environnement, pour interroger ces sociétés elles-mêmes.…”
Get full text

Hydrolase-Treated Royal Jelly Attenuates H2O2- and Glutamate-Induced SH-SY5Y Cell Damage and Promotes Cognitive Enhancement in a Rat Model of Vascular Dementia by Nualpun Sirinupong, Worrapanitch Chansuwan, Pratchaya Kaewkaen

“…This study determined the effects of royal jelly hydrolysate (RJH) and possible mechanism of cell damage and cognitive-enhancing effect in animal study. An in vitro study assessed the effects of RJH on acetylcholinesterase inhibitor, cell viability, and cell damage in SH-SY5Y neuroblastoma cells. …”
Get full text

Probiotic Amelioration of Azotemia in 5/6th Nephrectomized Sprague-Dawley Rats by Natarajan Ranganathan, Beena Patel, Pari Ranganathan, Joseph Marczely, Rahul Dheer, Tushar Chordia, Stephen R. Dunn, Eli A. Friedman

“…Subsequently, blood (retro-orbital) and urine (collected for measurements of blood urea-nitrogen and creatinine respectively), body weight and bacterial counts (feces) were obtained at regular intervals. …”
Get full text

Bioeconomía circular, una oportunidad de agregar valor y aumentar la competitividad de la cadena de valor leche-queso en México by María Magdalena Rojas Rojas, Karina Valencia Sandoval, José de Jesús Brambila Paz

“… El sector lechero es uno de los más importantes del país; pese a su importancia y a la alta demanda de productos de origen animal, esta industria se asocia a la contaminación ambiental debido a la acumulación de gases de efecto invernadero y a la producción de residuos. …”
Get full text

Investigating the antioxidant effects of Cucurbita maxima Duchesne extract on motor coordination and memory impairment induced by scopolamine in rats by Najmeh Asgharzadeh, Fatemeh Azizi, Mohammadreza Hojjati, Leila Roohi, Zahra Rabiei, Mehrdad Shahrani-Korani

“…Results: The results from the MWM indicated that animals receiving SCOP along with CM extract at concentrations of 50, 100, and 200 mg/kg spent significantly more time on the target platform compared to the SCOP-only group. …”
Get full text

Current Status and Global Research Trend Patterns of Insect Meal in Aquaculture From Scientometric Perspective: (2013–2022) by Raghuvaran N., Tincy Varghese, Prasanta Jana, Angela Brighty R. J., Muthiah Sethupathy A., Sudarshan S., Yahya Bin Abdullah Alrashdi, Adel Ehab Ibrahim, Sami El Deeb

“…In the past decade, insect meal has gained popularity in the animal feed industry, particularly in aquafeed, due to rising costs and decreased availability of fish meal (FM) and fish oil. …”
Get full text

Chemical Changes Under Heat Stress and Identification of Dendrillolactone, a New Diterpene Derivative with a Rare Rearranged Spongiane Skeleton from the Antarctic Marine Sponge <i>... by Andrea Prófumo, Conxita Avila, Adele Cutignano

“…This polar area is home to a large and rich community of benthic marine invertebrates, such as sponges, tunicates, corals, and many other animals. Among the sponges, the bright yellow <i>Dendrilla antarctica</i> is commonly known for using secondary diterpenoids as a defensive mechanism against local potential predators. …”
Get full text

Physical Activity and Quality of Life in Retinitis Pigmentosa by Joshua D. Levinson, Ethan Joseph, Laura A. Ward, Joe R. Nocera, Machelle T. Pardue, Beau B. Bruce, Jiong Yan

“…Aerobic exercise has been found to be neuroprotective in animal models of retinal degeneration. This study aims to report physical activity levels in patients with RP and investigate the relationship between physical activity and vision-related quality-of-life (QOL). …”
Get full text