Therapeutic applications of artemisinin in ophthalmic diseases by Hao Sun, Ping Zhao, Lianghui Zhao, Zhizhong Zhao, Haoyu Chen, Cong Ren, Bin Guo

“…However, since ocular diseases are often caused by various factors, how artemisinin can play a good disease prevention role by modulating these factors needs to be further verified, and most of the current studies focus on in vitro and animal experiments, lacking sufficient information on clinical trial studies. …”
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Effects of Cholecalciferol on Key Components of Vitamin D-Endo/Para/Autocrine System in Experimental Type 1 Diabetes by Anna Mazanova, Ihor Shymanskyi, Olha Lisakovska, Lala Hajiyeva, Yulia Komisarenko, Mykola Veliky

“…After 2 weeks of T1D, the animals were treated orally with or without vitamin D3 (cholecalciferol; 100 IU/rat, 30 days). …”
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Anthocyanins as functional food components by R. S. Yudina, E. I. Gordeeva, O. Yu. Shoeva, M. A. Tikhonova, E. K. Khlestkina

“…However, studies showed that in humans and animals, these compounds are actively metabolized and the bioavailability, estimated taking into account their metabolites, exceeded 12 %. …”
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The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats by Daria Chestnykh, Liubov S. Kalinichenko, Stephan von Hörsten, Johannes Kornhuber, Christian P. Müller

“…In subsequent tests, we utilized dimmed lighting and net-covered mirrors to induce incomplete mirror images. …”
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Feasibility study of emotion mimicry analysis in human–machine interaction by Herag Arabian, Tamer Abdulbaki Alshirbaji, Ashish Bhave, Verena Wagner-Hartl, Marcel Igel, J. Geoffrey Chase, Knut Moeller

“…The proposed system functions as a digital mirror, initially displaying an animated avatar’s face expressing a predefined emotion. …”
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Repurposing of phosphodiesterase-5 inhibitor sildenafil as a therapeutic agent to prevent gastric cancer growth through suppressing c-MYC stability for IL-6 transcription by Zhenzhan Zhang, Wuqing Huang, Donghua Huang, Zhou Xu, Qingfeng Xie, Xin Tan, Wenjun He, Weihao Yang, Guoxin Li, Jianguang Ji, Hao Liu

“…The anti-tumor effect and mechanism of the PDE5 inhibitor sildenafil were evaluated via using tumor cells, patient-derived tumor organoids and xenograft animal models in GC. A total of 161 Swedish GC patients from a nationwide population-based cohort who received post-diagnostic PDE5 inhibitors demonstrated lower cancer-specific mortality compared to the controls (HR = 0.66, 95% CI = 0.47-0.92, P = 0.016). …”
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An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity by Pierre Guermonprez, Le Tu Anh, Louis Renaud, Pierre Nioche, Eric Krejci, Aurélie Alleaume-Butaux, Nicolas Battaglini, Vu Thi Thu, Sébastien Sanaur, Benoît Piro

“…Detection of Ribonucleic acids (RNA) is a critical step in the identification of viral or bacterial infections in humans and animals. Reverse transcriptase-polymerase chain reaction (RT-PCR) remains the gold standard, but clustered regularly interspaced short palindromic repeats linked to a Cas endoribonuclease particle (CRISPR/Cas) have recently revolutionized the recognition step of two RNAs, i.e. the CRISPR-RNA (crRNA) and the target, providing a much better selectivity compared to the naked hybridization on which RT-PCR is based. …”
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Pathogenesis and Rehabilitation Therapy of Sleep Disorder after Stroke by HAN Xu, XIE Hongyu, TANG Xinwei, WU Yi

“…Future explorations are needed on experimental animal models suitable for the basic research on post-stroke sleep disorder. …”
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Utilizing the Ellik bladder evacuator during cystoscopic retrieval of urocystoliths in 12 dogs by John Shamoun, Shelly L. Vaden, Allison R. Kendall, Patricia L. Secoura

“…Methods In this retrospective study, dog demographics, procedure type and duration, and clinical outcomes of dogs undergoing cystoscopic cystolith retrieval utilizing the EE are described. Results Twelve dogs underwent 13 cystoscopic procedures utilizing EE for cystolith retrieval. …”
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Human Health, Ecosystem Quality, and Resource Scarcity Burdens Inflicted by Livestock Production Across Chinese Regions by Yixuan Shao, Qilin Cao, Junnian Song, Jiahao Xing, You Wu, Cheng Sun, Pan He, Wei Yang

“…Abstract Surge in global population and shift toward animal‐based diets have accelerated expansion of livestock production, posing various environmental challenges. …”
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Escherichia coli O157:H7 Bacteria Antibiotic Resistant Isolated from Flies at Food Courts in IPB Dramaga Campus by Muhammad Rizki Aminudin, Denny Widaya Lukman, Mirnawati Bachrum Sudarwanto, Herwin Pisestyani

“…Several human and animal pathogens transmit into the food chain through houseflies as mechanical vectors, one of which is E. coli O157:H7. …”
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The Role of Artificial Lakes Located in Forests in the Context of Small Retention, Biodiversity and Climatic Changes—Evidence From Southern Poland by Rafał Starzak, Anna Cieplok, Robert Czerniawski, Aneta Spyra

“…It should be assumed that with ongoing climate change, these phenomena will probably intensify, which will lead to changes in entire ecosystems at plant and animal levels.…”
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Molecular Determination of Toxocara spp. Eggs Isolated from Public Parks and Playgrounds in Zahedan, Southeast Iran by Siavash Liravizadeh, Samaneh Abdolahi Khabisi, Alireza Salimi Khorashad, Hadi Mirahmadi

“…As evidenced by the obtained results, only T. cati species were detected in public parks and playgrounds in Zahedan; therefore, control and prevention programs against this species should be considered in human and animal communities.…”
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One Earth-One Health (OE-OH): Antibacterial Effects of Plant Flavonoids in Combination with Clinical Antibiotics with Various Mechanisms by Ganjun Yuan, Fengxian Lian, Yu Yan, Yu Wang, Li Zhang, Jianping Zhu, Aiman Fatima, Yuxing Qian

“…Considering that various metabolites from microorganisms, plants, and animals on the Earth would definitely impact the evolution of AMR, together with the rules, key factors, and important principles of drug combination for preventing AMR, we further propose the “One Earth-One Health (OE-OH)” concept, emphasizing ecosystem interactions in AMR prevention.…”
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A functional approach to analyze the genetic basis for differences in virulence of monkeypox virus clades by Patricia L. Earl, Jeffrey L. Americo, Sara Reynolds, Wei Xiao, Catherine Cotter, Bernard Moss

“…Virulence was determined by live animal imaging in addition to weight loss and survival. …”
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Effect of N-Acetylcysteine on Dyslipidemia and Carbohydrate Metabolism in STZ-Induced Diabetic Rats by Anderson Kiyoshi Kaga, Pedro Octavio Barbanera, Nágilla Orleanne Lima do Carmo, Lucas Rodolfo de Oliveira Rosa, Ana Angélica Henrique Fernandes

“…T1DM was induced using STZ (60 mg/kg, ip; single dose), and NAC (25 mg/kg/day) was administrated by gavage, for 37 days. The animals received chow and water ad libitum. After the experimental period, blood and cardiac tissue samples were collected to analyze energetic metabolism, lipid profile, and AI. …”
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A meiotic mystery in experimental hybrids of the eastern mole vole (Ellobius tancrei, Mammalia, Rodentia) by V. G. Tambovtseva, S. N. Matveevsky, A. A. Kashintsova, A. V. Tretiakov, O. L. Kolomiets, I. Yu. Bakloushinskaya

“…In 10 years of inbred crossings (sister – brother), we got 9 generations of hybrids (262 litters, 578 animals). In the first hybrid generation, two trivalents, a tetravalent and 20 bivalents were revealed at meiotic prophase I. …”
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Phenoxybenzamine in Complex Regional Pain Syndrome: Potential Role and Novel Mechanisms by Mario A. Inchiosa

“…The syndrome develops in the absence of any apparent continuation of the inciting trauma. …”
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Dentin-Derived Inorganic Minerals Promote the Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells: Potential Applications for Bone Regeneration by Gang Lei, Yanqiu Wang, Yan Yu, Zehan Li, Jiamin Lu, Xingyun Ge, Na Li, Ana Gloria Cuba Manduca, Jinhua Yu

“…The activation in ERK and p38 signals was detected in DIM-treated BMMSCs, and both pathways and osteogenic process were suppressed while using ERK inhibitor U0126 and p38 inhibitor SB203580, respectively. Furthermore, the animal experiments revealed that DIM could dramatically enhance new bone formation compared to the control group. …”
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Genetic parameters for lifetime productivity in Holstein and Brown Swiss dairy cows in Honduras by Karen Alessa Copas-Medina, Manuel Valladares-Rodas, Juan José Baeza-Rodríguez, José Candelario Segura-Correa, Juan Magaña-Monforte

“…The model for AFP assessed the effect of contemporary group (herd, year and birth season combination) as fixed. The model used for L, UL and P included the contemporary group, age group at first calving and their interaction. …”
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