Renal Effects of Hyperbaric Oxygen Therapy in Patients with Diabetes Mellitus: A Retrospective Study by Martin Sedlacek, Nicole P. Harlan, Jay C. Buckey

“…The prolonged high oxygen level used in HBOT can produce oxidative stress, which may be harmful to the kidney. Animal experiments suggest HBOT does not harm renal function and may have an antiproteinuric effect, but little is known on the effect of HBOT in humans. …”
Get full text

Analysis of the cardiotoxic and myorelaxant effects of camphor on fish of the Nile tilapia species (Oreochromis niloticus) (Linnaeus 1758) by Clarissa Araújo da Paz, Suzane Maia de Oliveira, Maria Klara Otake Hamoy, Murilo Farias dos Santos, Anthony Lucas Gurgel do Amaral, Anara de Sousa Barbosa, Luciana Eiró-Quirino, Daércio José de Macedo Ribeiro Paixão, Luis André Luz Barbas, Dielly Catrina Favacho Lopes, Marcelo Ferreira Torres, Moisés Hamoy

“…However, the use of a concentration of 300 mg L−1 makes the cardiac and respiratory effects more evident, with changes in the tracing, which can harm the animal’s hemodynamics. However, lower concentrations (150 mg L−1) showed tachycardia and opercular hypermotility, demonstrating changes not compatible with anesthesia. …”
Get full text

Zearalenone exacerbates lipid metabolism disorders by promoting liver lipid droplet formation and disrupting gut microbiota by Xiao Han, Bingxin Huangfu, Tongxiao Xu, Kunlun Huang, Xiaoyun He

“…ZEA has the ability to bind to estrogen receptors of humans and animals and is an environmental endocrine disruptor that may interfere with glucose homeostasis and lipid metabolism. …”
Get full text

<i>Musa paradisiaca</i> L. Inflorescence Abrogates Neutrophil Activation by Downregulating TLR4/NF-KB Signaling Pathway in LPS-Induced Acute Lung Injury Model by Francisco Allysson Assis Ferreira Gadelha, Raquel Fragoso Pereira Cavalcanti, Cosmo Isaias Duvirgens Vieira, Joao Batista De Oliveira, Louíse Mangueira De Lima, Adriano Francisco Alves, Matheus Marley Bezerra Pessoa, Leônia Maria Batista, Naiara Naiana Dejani, Marcia Regina Piuvezam

“…<b>Methods</b>: Swiss mice were challenged with lipopolysaccharide and treated with HEM after 1, 24, and 48 h (five animals/group, three times). <b>Results</b>: The HEM-treated ALI mice presented a decrease in neutrophil migration in the bronchoalveolar lavage fluid (BALF), in the alveolar region, and in the blood, correlating to downregulation of CD18 expression. …”
Get full text

Structures of Astaxanthin and Their Consequences for Therapeutic Application by Tatas Hardo Panintingjati Brotosudarmo, Leenawaty Limantara, Edi Setiyono, Heriyanto

“…Astaxanthin contains both a hydroxyl and a keto group, and this unique structure plays important roles in neutralizing ROS. …”
Get full text

Toll-Like Receptor-4 Mediated Inflammation Is Involved in the Cardiometabolic Alterations Induced by Intermittent Hypoxia by Laureline Poulain, Vincent Richard, Patrick Lévy, Maurice Dematteis, Claire Arnaud

“…Lean adult male TLR4-deficient (TLR4−/−) mice and their controls (C57BL/6 mice) were exposed to either IH (FiO2 21-5%, 1 min cycle, 8 h/day) or air (normoxic mice) for 4 weeks. Animals were assessed at 1-week exposure for insulin tolerance test and after 4-week exposure for morphological and inflammatory changes of the epididymal fat and thoracic aorta. …”
Get full text

Modo de vida camponês e identidade indígena na Comunidade Dom Pedro II, em Barcelos, AM by Talita Pedrosa Vieira de Carvalho Benfica, Martha Benfica do Nascimento de Carvalho, Antônio Carlos Witkoski

“…This subject performs several work activities: cultivation (agriculture, handling of medicinal plants in the peasant property), animal extractivism (fishing and hunting) and vegetable extractivism (collection of fruits and medicinal plants). …”
Get full text

Structural elucidation of mulberry leaf oligosaccharide and its selective promotion of gut microbiota to alleviate type 2 diabetes mellitus by Tenggen Hu, Yuanshan Yu, Jijun Wu, Yujuan Xu, Gengsheng Xiao, Kejing An, Erna Li, Sentai Liao, Yuxiao Zou

“…Gut microbiota analysis revealed that MLO 2-1 selectively promoted the growth of Ligilactobacillus murinus, a commensal bacterium presented a reduced level in T2DM mice. Animal experiments indicated that MLO 2-1 and L. murinus exhibited hypoglycemic activities. …”
Get full text

Detection of Francisellaceae and the differentiation of main European F. tularensis ssp. holarctica strains (Clades) by new designed qPCR assays by Kristin Köppen, Kerstin Rydzewski, Julia Zajac, Marwah Al-Senwi, Sema Evcimen, Darius Schulze, Daniela Jacob, Klaus Heuner

“…Conclusion Since the developed qPCRs are able to detect all genera of Francisellaceae tested, an easy and fast identification of opportunistic Francisella strains causing tularemia-like symptoms in humans or animals is possible now. The application of these qPCR assays will thus improve the capability for clinical diagnostics and molecular typing during epidemiological investigations.…”
Get full text

Selective Glucocorticoid Receptor (GR-II) Antagonist Reduces Body Weight Gain in Mice by Tomoko Asagami, Joseph K. Belanoff, Junya Azuma, Christine M. Blasey, Robin D. Clark, Philip S. Tsao

“…Previous research has shown that mifepristone can prevent and reverse weight gain in animals and human subjects taking antipsychotic medications. …”
Get full text

Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder by Inna Shomer, Nofar Mor, Shaul Raviv, Noga Budick-Harmelin, Tanya Matchevich, Sharon Avkin-Nachum, Yoach Rais, Rebecca Haffner-Krausz, Ariela Haimovich, Aviv Ziv, Reut Fluss, Bruria Ben-Ze’ev, Gali Heimer, Denis N. Silachev, Vladimir L. Katanaev, Dan Dominissini

“…Due to sequence similarity, the mouse can be treated with the selected ASO to test treatment efficacy in animal models, as shown in vitro using murine neural progenitor cells. …”
Get full text

Topically Applied Connective Tissue Growth Factor/CCN2 Improves Diabetic Preclinical Cutaneous Wound Healing: Potential Role for CTGF in Human Diabetic Foot Ulcer Healing by F. R. Henshaw, P. Boughton, L. Lo, S. V. McLennan, S. M. Twigg

“…Granulation tissue from CTGF treatment in diabetic wounds showed collagen IV accumulation compared with nondiabetic animals. Wound α-smooth muscle actin was increased in CTGF treated diabetic wounds compared with untreated diabetic wounds, as was macrophage infiltration. …”
Get full text

Protective Effect of Opuntia dillenii (Ker Gawl.) Haw. Seed Oil on Gentamicin-Induced Nephrotoxicity: A Biochemical and Histological Analysis by Mohamed Bouhrim, Noureddine Bencheikh, Hamada Imtara, Nour Elhouda Daoudi, Hamza Mechchate, Hayat Ouassou, Loubna Kharchoufa, Mostafa Elachouri, Hassane Mekhfi, Abderrahim Ziyyat, Abdelkhaleq Legssyer, Mohammed Aziz, Mohamed Bnouham

“…The present study aims to investigate the protective effect of Opuntia dillenii seed oil against gentamicin-induced nephrotoxicity in rats. The animals (rats) were randomly divided into three groups (i) the normal control group treated only with distilled water (10 mL/kg), (ii) the gentamicin group treated with distilled water (10 mL/kg) and received an intraperitoneal injection of gentamicin (80 mg/kg), and (iii) the group treated with the Opuntia dillenii seed oil (2 mL/kg) and also received an intraperitoneal injection of gentamicin (80 mg/kg). …”
Get full text

STUDY OF GERMINATION REGARDING THE COMBAT OF WEEDS IN MEADOWS WITH REFERENCE TO CIRSIUM VULGARE SPECIES by Lisena Piscoran, Teodor Rusu

“…The meadow is the land surface covered with grassy vegetation, made up mostly of perennial plants, belonging to different botanical families, the production of which is used for feeding animals, by grazing or mowing. Cirsium vulgare, the spear thistle, bull thistle or common thistle, is a species of the Asteraceae genus Cirsium, widespread throughout Europe, western Asia and northwestern Africa. …”
Get full text

The R18 Polyarginine Peptide Is More Effective Than the TAT-NR2B9c (NA-1) Peptide When Administered 60 Minutes after Permanent Middle Cerebral Artery Occlusion in the Rat by D. Milani, N. W. Knuckey, R. S. Anderton, J. L. Cross, B. P. Meloni

“…At 24 hours after MCAO, there was reduced total infarct volume in R18 treated animals at all doses, but this reduction only reached statistical significance at doses of 100 and 1000 nmol/kg. …”
Get full text

Molecular aspects of cell-penetrating peptides: key amino acids, membrane partners, and non-covalent interactions by Walrant, Astrid, Tazi, Farah, Khemaissa, Sonia, Sagan, Sandrine

“…Floating above the lipid bilayer, negatively charged proteoglycans and other polysaccharides form a viscous, anionic matrix layer surrounding animal cells, which CPPs have to go through to reach the lipid bilayer. …”
Get full text

The Efficacy of Madeira Vine Leaf Extract Combined with Turmeric Rhizome Extract Gel Topically on Second-Degree Burn Wound in Albino Rats by Mirza Atikah Madarina Hisyam, Wiwik Misaco Yuniarti, Sis Wisnuarti Theresia, Ira Sari Yudaniayanti, Bambang Sektiari Lukiswanto, Sri Agus Sudjarwo, Thomas Valentinus Widiyatno

“…Burns is now considered one of the most destructive forms of trauma affecting humans and animals. This study aimed to determine the effect of Madeira vine leaf extract combined with 2% Turmeric rhizome extract (MVLTR) gel administered topically on second-degree burn wound in albino rats based on the number of fibroblasts. …”
Get full text

Problems and prospects for livestock industry development in the context of digitalization of the agro-industrial complex in the region (based on the materials of the Republic of B... by Z. T. Nasretdinova, A. M. Khazieva, A. R. Nasretdinova

“…The key problems have been highlighted, such as lack of a unified digital platform, low level of digital competencies, financial constraints, lack of a unified strategy, and resistance to digital transformation. …”
Get full text

The Usage of Lion’s Mane in Sports and Its Metabolic Impact – a literature review by Karolina Stankevič, Kamila Fuczyło, Ewelina Kopczyńska, Piotr Kulej, Wiktor Biesiada, Justyna Weronika Kmieć, Justyna Woźniak, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński

“…The review includes an exploration of the biochemical properties of lion’s mane and their relevance to athletic performance, assessment of the evidence gathered from animal and human studies regarding its potential benefits, identifying the gaps in research and proposing directions for future studies. …”
Get full text

Tissue-Welding Device: Considerable Advantages for Spleen Surgery Based on Histological and Cardiorespiratory Investigation by Linda Gatiņa, Inga Piginka-Vjaceslavova, Dace Bērziņa, Maksims Zolovs

“…Spleen biopsies of the incision area were taken from each animal at the day 0, 7, and 14 after surgery. Contactless thermography was performed during surgery. …”
Get full text