Injectable supramolecular hydrogel co-loading abemaciclib/NLG919 for neoadjuvant immunotherapy of triple-negative breast cancer by Binyu Zhu, Ying Cai, Lingli Zhou, Lei Zhao, Jiameng Chen, Xiaoting Shan, Xujie Sun, Qian You, Xiang Gong, Wen Zhang, Helen He Zhu, Pengcheng Zhang, Yaping Li

“…The neoadjuvant immunotherapy reduces tumor recurrence and pulmonary metastasis and prolongs the survival of animals. This hydrogel provides a potential platform for neoadjuvant immunotherapy of triple-negative breast cancer with reduced toxicity compared with free abemaciclib.…”
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Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals. by Wilhelm Palm, Marta M Swierczynska, Veena Kumari, Monika Ehrhart-Bornstein, Stefan R Bornstein, Suzanne Eaton

“…Hedgehog (Hh) proteins control animal development and tissue homeostasis. They activate gene expression by regulating processing, stability, and activation of Gli/Cubitus interruptus (Ci) transcription factors. …”
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Expanding Yarrowia lipolytica’s metabolic potential for detoxification of cyanogenic glycosides in edible plants by Fidelis Azi, Zhiyu Li, Peng Xu

“…The findings demonstrate that the strain is a robust, sustainable, and potentially efficient strain that could be used for industrial bioconversion of plant materials containing glycosylated toxicants into safe foods and animal feeds.…”
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Assessment of Safety and Therapeutic Efficacy of Rosa damascena L. and Quercus infectoria on Cardiovascular Performance of Normal and Hyperlipidemic Rabbits: Physiologically Based... by Siyavash Joukar, Masoumeh Askarzadeh, Beydolah Shahouzehi, Hamid Najafipour, Hossein Fathpour

“…(RD) for therapeutic purposes and lack of adequate information about their cardiovascular effects, we investigated the cardiovascular indices of rabbits which chronically pretreated with these agents. Animal groups were control group (CTL), RD and QI groups with normal chow plus 1.5 g RD and QI extracts, respectively, in each kg of the diet for 45 days; Hyperlipidemic (H) group received high-fat diet for 45 days; H+RD and H+QI groups received high fat diet plus QI and RD extracts, respectively. …”
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The Effect of Mechanical Ventilation on TASK-1 Expression in the Brain in a Rat Model by Buqi Na, Hong Zhang, Guangfa Wang, Li Dai, Guoguang Xia

“…Male Sprague-Dawley rats were randomized to three groups: (1) high tidal volume (HVt): MV for four hours with Vt at 10 mL/kg; (2) low Vt (LVt): MV for four hours with Vt at 5 mL/kg; (3) basal (BAS): anesthetized and unventilated animals. We measured lung histology and plasma and brain levels of proteins (IL-6, TNF-α, and S-100B) and determined TASK-1 levels in rat brainstems as a marker of respiratory centre activity. …”
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Essential oils used in the poultry industry: Would it be an effective green alternative against Salmonella spp. dissemination and antimicrobial resistance? by Heitor Leocádio de Souza Rodrigues, Isis Mari Miyashiro Kolososki, Valdinete Pereira Benevides, Mauro M.S. Saraiva, Angelo Berchieri Junior

“…Due to the increasing emergence of antimicrobial-resistant strains of Salmonella spp. isolated from poultry, and the global trend towards reducing antimicrobial use in food-producing animals, alternatives to these drugs are being sought. …”
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Micro-PET/CT Monitoring of Herpes Thymidine Kinase Suicide Gene Therapy in a Prostate Cancer Xenograft: The Advantage of a Cell-specific Transcriptional Targeting Approach by Mai Johnson, Makoto Sato, Jeremy Burton, Sanjiv S. Gambhir, Michael Carey, Lily Wu

“…Liver serology, tissue histology, and frail condition of animals confirmed liver toxicity suffered by the constitutive active cohorts, whereas the prostate-targeted group was unaffected. …”
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Effectiveness of Fibers from “Cabernet Sauvignon” (Vitis vinifera) Pomace as Fining Agents for Red Wines by Mariona Gil, Rubén Del Barrio-Galán, Cristina Úbeda, Álvaro Peña-Neira

“…Recent findings have highlighted the potential of fibers from grape cell wall material to be fining agents for red wines as alternatives to animal-derived proteins. The affinity of those fibers for grape proanthocyanidins (also known as condensed tannins) seems to depend on the initial phenolic composition of the wines to be fined and on the applied dose of fibers. …”
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Study on the Influence of Scaling‐Up in the Transesterification Process for the Synthesis of Biodegradable Monoglycerides of Fatty Acids by Roland Nagy, Rebeka Bejczi

“…ABSTRACT Fatty acids and monoglycerides from vegetable oils or animal fats are crucial in various industries. Monoglycerides, with their hydrophilic and hydrophobic properties, act as effective non‐ionic surfactants for oil‐in‐water emulsions. …”
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Microplastic accumulation in snake-eyed lizard (Ophisops elegans Menetries, 1832) after long-term monitoring: habitats matter, not years by Cantekin Dursun, Kamil Candan, Kaan Karaoğlu, Çetin Ilgaz, Yusuf Kumlutaş, Elif Yıldırım Caynak, Serkan Gül

“…The ingestion of MPs disrupts the food web, causing physical and chemical harm to animals at multiple trophic levels. Here, we studied the accumulation of MPs in the gastrointestinal tracts (GITs) of a terrestrial lizard species after long-term monitoring using museum specimens in the collection of the Fauna and Flora Research and Application Center at Dokuz Eylül University from decades ago. …”
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The Eurasian Magpie Preys on the Nests of Vinous‐throated Parrotbills in Invasive Smooth Cordgrass by Yanhong Chen, Youle Xu, Junjie Wang, Taiyu Chen, Bin Liu, Pan Chen, Changhu Lu

“…ABSTRACT Native animals worldwide are experiencing long‐term coexistence with invasive plants, leading to diverse behavioral changes. …”
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Prevalence of Dermatological Presentations of Canine Leishmaniasis in a Nonendemic Area: A Retrospective Study of 100 Dogs by Roberta Perego, Daniela Proverbio, Giada Bagnagatti De Giorgi, Eva Spada

“…Thirty-two percent of dogs were mixed breeds; the remainder represented a variety of pure breeds. …”
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Identificación microbiológica de algunas cepas nativas cultivables asociadas al tracto digestivo en Panaque cochliodon by Juan David Cano-Gil, Luz Adriana Gutiérrez-Ramírez, Carlos A. David-Ruales, Sandra Pardo-Carrasco, Valentina Jaramillo-Ruiz, Manuela Arboleda-Restrepo

“…Se utilizaron tres ejemplares adultos de la especie Panaque cochliodon capturados en el río Magdalena que fueron transportados y sacrificados bajo normas de bienestar animal. Se realizó disección del tracto intestinal obteniendo muestras para el aislamiento microbiológico, usando medios de cultivo selectivos, purificando los microrganismos, realizando pruebas bioquímicas metabólicas y pruebas API 20E (Biomeriux) para su identificación. …”
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Trade in floodplain medieval settlements of the Lower Kama region in the XII–XIV centuries (based on the finds of metal mirrors) by Rudenko Konstantin A., Kazakov Evgeniy P.

“…Mirrors with complex compositions, for example, running wild animals, as well as copies of Chinese mirrors with dragons and wise men, are rare. …”
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Exosome-loading miR-205: a two-pronged approach to ocular neovascularization therapy by Hui-ying Zhang, Qiu-yang Zhang, Qing Liu, Si-guo Feng, Yan Ma, Feng-sheng Wang, Yue Zhu, Jin Yao, Biao Yan

“…This innovative approach avoids cytotoxicity while preserving therapeutic efficacy in both cellular and animal models. Collectively, our findings highlight miR-205 as a promising therapeutic for ocular neovascularization, with exosome delivery offering a novel and efficient strategy for treating vision-threatening vascular diseases. …”
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Extract of Sesbania grandiflora Ameliorates Hyperglycemia in High Fat Diet-Streptozotocin Induced Experimental Diabetes Mellitus by Ghanshyam Panigrahi, Chhayakanta Panda, Arjun Patra

“…During the experimental period, body weight, abdominal girth, food intake, fasting serum glucose, urine analyses were measured. Insulin tolerance test was carried out on 25th day of drug treatment period. …”
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Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. by Zuzana Pavlíčková, Barbora Pafčo, Vladislav Ilík, Lee O'Brien Andersen, Milan Jirků, Kristýna Brožová, David Modrý, Oldřiška Kadlecová, Christen Rune Stensvold, Kateřina Jirků

“…Among these factors, habitat sharing with other humans and companion animals, especially dogs, is considered crucial together with the presence of intestinal protists. …”
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Morphology of the Myoepithelial Cell: Immunohistochemical Characterization from Resting to Motile Phase by Germana Beha, Giuseppe Sarli, Barbara Brunetti, Francesco Sassi, Domenico Ferrara, Cinzia Benazzi

“…All these antibodies were also tested on 3 mammary tissues from animals with no mammary pathology. The myoepithelial markers were well expressed in the suprabasal cells and gradually lost in the motile types, with the stellate cells maintaining only VIM expression typical of mesenchyma. …”
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In vivo bone regeneration performance of hydroxypropyl methylcellulose hydrogel-based composite bone cements in ovariectomized and ovary-intact rats: a preliminary investigation by Mosharraf Hossain, Tamima Sultana, Ji Eun Moon, Soobin Im, Je Hoon Jeong

“…Abstract The objective of this study is to fabricate and develop hydroxypropyl methylcellulose (HPMC) hydrogel (HG)-based composite bone cements with incorporation of hydroxyapatite (HA), beta-tricalcium phosphate (β-TCP), and with/without polymethylmethacrylate (PMMA) for vertebroplasty. For animal study, twenty female Wister rats (250–300 g, 12 weeks of age) were divided into four groups including a two non-ovariectomy (NOVX) groups and two ovariectomy (OVX)-induced osteoporosis groups. …”
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An mRNA-Based Respiratory Syncytial Virus Vaccine Elicits Strong Neutralizing Antibody Responses and Protects Rodents Without Vaccine-Associated Enhanced Respiratory Disease by Jianglong Li, Haiyan Long, Shaoyi Chen, Zhendong Zhang, Shuang Li, Qi Liu, Jun Liu, Jiaru Cai, Liping Luo, Yucai Peng

“…Results: LVRNA007 induced robust humoral and cellular immune responses in both mice and cotton rats, with neutralization antibody levels in the immunized animals maintained at high levels for over one year. …”
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