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  1. 40061

    Recovery of the Cell Cycle Inhibition in CCl4-Induced Cirrhosis by the Adenosine Derivative IFC-305 by Victoria Chagoya de Sánchez, Lidia Martínez-Pérez, Rolando Hernández-Muñoz, Gabriela Velasco-Loyden

    Published 2012-01-01
    “…Diminution and small changes were observed in the studied proteins in the cirrhotic animals without treatment. The IFC-305-treated rats showed a clear increase in most of the proteins studied mainly in PCNA and CDK6, and a marked increased in ATP and mitochondrial function. …”
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  2. 40062
  3. 40063

    Reproductive performance and increased fecundity in the chinchilla (Chinchilla laniger Molina) by M. V. Novikov, N. N. Shumilina

    Published 2015-07-01
    “…Litter size is affected by the genotype and conformation of animals, as well as by paratypic factors acting during pregnancy and whelping. …”
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  4. 40064

    Analgesic, Antioxidant, Anti-Inflammatory, and Wound-Treating Actions of Bitter Apricot Kernel Extract by Mohamed Amine El-Hajjaji, Kawtar Fikri-Benbrahim, Najoua Soulo, Ghizlane Nouioura, Hassan Laaroussi, Pedro Ferreira-Santos, Badiaa Lyoussi, Zineb Benziane Ouaritini

    Published 2024-01-01
    “…In the anti-inflammatory test, significant inhibition was observed after 6 hours of treatment (77.4%) compared to untreated animals. Moreover, the daily application of ointment formulated with 10% BAK extract resulted in a remarkable healing of wounds and burns in rats. …”
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  5. 40065

    A Bayesian Inference-Based Method for Uncertainty Analysis in Raman Spectroscopy by Hanxuan Zhou

    Published 2025-01-01
    “…In experiments on an animal blood Raman spectroscopy dataset (both reflection and transmission modes), the proposed method achieves classification accuracies of 95.36% and 94.83%, respectively, showing slight improvements over other classical machine learning and neural network methods. …”
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  6. 40066

    Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway by Jiawei He, Anhui Yang, Xuyu Zhao, Yang Liu, Shuyan Liu, Di Wang

    Published 2021-07-01
    “…Eight-week administration with GIPS at doses of 30 or 90 mg/kg strongly inhibited tumor growth including the reduction on numbers and the suppression of the size without influencing the animals’ body weight and organ functions. According to the proteomics performing by antibody array, among 308 detected cytokines, GIPS significantly regulated 89 of them. …”
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  7. 40067

    Evaluation on Antidiabetic Properties of Medicinal Plants from Myanmar by Dongdong Zhang, Karuppusamy Arunachalam, Yuehu Wang, Yu Zhang, Jun Yang, Pyae Phyo Hein, Aye Mya Mon, Jianwen Li, Angkhana Inta, Xuefei Yang

    Published 2021-01-01
    “…P. zeylanica, L. cubeba, H. crenulate, M. gagei, C. teeta, and M. ferrea are worthy to advance further study according to their strong antidiabetic activities and limited research on effects in in vivo animal studies, unclear chemical constitutes, and safety.…”
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  8. 40068

    Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model by Chih-Zen Chang, Chih-Lung Lin, Shu-Chuan Wu, Aij-Lie Kwan

    Published 2014-01-01
    “…High-mobility group box 1 (HMGB1) was shown to be an important extracellular mediator involved in vascular inflammation of animals following subarachnoid hemorrhage (SAH). This study is of interest to examine the efficacy of purpurogallin, a natural phenol, on the alternation of cytokines and HMGB1 in a SAH model. …”
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  9. 40069

    Intrapericardial injection of hydrogels with ASC and their secretome to treat dilated cardiomyopathies by Tácia Tavares Aquinas Liguori, Gabriel Romero Liguori, Viktor Sinkunas, Cristiano Jesus Correia, Raphael dos Santos Coutinho e Silva, Fernando Luiz Zanoni, Vera Demarchi Aiello, Martin Conrad Harmsen, Luiz Felipe Pinho Moreira

    Published 2025-01-01
    “…Compared to saline controls, interstitial myocardial fibrosis was reduced in ASC/CMed-loaded hydrogels treated animals (p = 0.0139). Ejection fraction and cardiac work efficiency improved in the ASC/CMed-treated rats compared to saline treatment (p = 0.0151 and p = 0.0655, respectively). …”
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  10. 40070

    ARRANGEMENT AND IMPLEMENTATION OF REGIONAL OFFICIAL VETERINARY SURVEILLANCE IN RUSSIAN FEDERATION IN 2016 by M. A. Shibayev, I. M. Klinovitskaya, A. S. Oganesyan, A. V. Belchikhina, K. N. Gruzdev, A. K. Karaulov, N. V. Lebedev

    Published 2018-04-01
    “…It was concluded that for the purpose of adequate public protection the transition from total control to risk-oriented policy is needed and that risk-oriented policy should involve planning of checks depending on the animal health risk level. It is additionally urgent to pay closer attention to the development and revision of unified approaches to determination of inspectors' staff size and improvement of methodical approaches to the calculation of financial expenses on surveillance implementation. …”
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  11. 40071

    Deciphering Oxidative Stress in Cardiovascular Disease Progression: A Blueprint for Mechanistic Understanding and Therapeutic Innovation by Zhaoshan Zhang, Jiawei Guo

    Published 2024-12-01
    “…Second, it summarizes the cardiovascular protective effects, mechanisms of action, and animal models of various antioxidants, offering insights into future drug development. …”
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  12. 40072

    Therapeutic efficacy of intra-articular injection of human adipose-derived mesenchymal stem cells in a sheep model of knee osteoarthritis by Jigang Lei, Xingyi Chen, Haohao Xie, Yuhao Dai, Zhongjin Chen, Liang Xu

    Published 2025-01-01
    “…Nonetheless, little is known about the efficacy of human adipose-derived mesenchymal stem cells (haMSCs) for KOA in large animal models. Methods This study evaluated the therapeutic efficacy of haMSCs in knee articular cartilage repair in a sheep model of KOA. haMSCs were isolated, cultured, and characterized. …”
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  13. 40073

    The roles of pleiotrophin in brain injuries: a narrative review of the literature by Yupeng Lei, Ruixi Zhou, Qian Mao, Xia Qiu, Dezhi Mu

    Published 2025-12-01
    “…Considering this, this review focuses on the roles and related regulatory pathways of PTN in brain injuries, what is known to date.Methods PubMed and Embase databases have been searched, and related studies are compiled and summarized.Results Our review has found PTN participates in the repairment of brain injuries, including hypoxic-ischemic brain injury, preterm white matter injury, traumatic brain injury, and neurodegenerative diseases, mainly based on animal data and small sample size studies. Besides, PTN interacts with receptors, such as, Z-type protein tyrosine phosphatase receptor and syndecan-3, regulating related pathways in these events.Conclusion It suggests PTN as a promising candidate for the treatment of brain injuries clinically. …”
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  14. 40074

    Phytochemical Analysis and Antimalarial Activity Aqueous Extract of Lecaniodiscus cupanioides Root by Mikhail Olugbemiro Nafiu, Taoheed Adedeji Abdulsalam, Musbau Adewumi Akanji

    Published 2013-01-01
    “…Twenty-four (24) albino mice were infected by intraperitoneal injection of standard inoculum of chloroquine sensitive Plasmodium berghei (NK 65). The animals were randomly divided into 6 groups of 3 mice each. …”
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  15. 40075
  16. 40076

    Pharmalens Augmented Reality Application For The Dangers of Illegal Drugs by A. Muh. Nurul Akbar, Imran Firman

    Published 2024-12-01
    “…An interactive application was developed using the Multimedia Development Life Cycle (MDLC) method, particularly the Luther-Sutopo model, integrating multimedia elements such as images, audio, video, animations, and educational articles. The application employs Augmented Reality (AR) technology, specifically Marker-Based Tracking, to display virtual 3D models triggered by markers or images. …”
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  17. 40077

    Serum lipid and protein profiles of theileria equi seropositive and seronegative horses by İbrahim Balkaya, Özgür Kaynar, Armağan Erdem Ütük, Fatma Çiğdem Pişkin

    “…Additionally, globulin levels of T. equi seropositive animals were observed to have increased, although albumin levels of both healthy and T. equi seropositive horses were similar. …”
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  18. 40078

    Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells. by Eric Cheng, Ran Lu, Abigail R Gerhold

    Published 2024-12-01
    “…How these cells ensure proper chromosome segregation, and thereby maintain mitotic fidelity, in the complex physiological environment of a living animal is poorly understood. Here we use in situ live-cell imaging of C. elegans germline stem and progenitor cells (GSPCs) to ask how the signaling environment influences stem and progenitor cell mitosis in vivo. …”
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  19. 40079

    Role of estuarine natural processes in removal of trace metals under emergency situations by A.R. Karbassi, S. Tajziehchi, N. Farhang Adib

    Published 2016-01-01
    “…For this purpose artificial river water containing high concentration of Mn, Cu, Zn, Ni and Pb were mixed with sea water at different salinity regimes. …”
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  20. 40080

    Humoral Bone Morphogenetic Protein 2 Is Sufficient for Inducing Breast Cancer Microcalcification by Fangbing Liu, Nathalie Bloch, Kumar R. Bhushan, Alec M. De Grand, Eiichi Tanaka, Stephanie Solazzo, Pawel M. Mertyna, Nahum Goldberg, John V. Frangioni, Robert E. Lenkinski

    Published 2008-07-01
    “…Tumor growth and calcium salt deposition were quantified in living animals over time using micro–computed tomography and probed chemically using near-infrared fluorescence. …”
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