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40001
Nutritional cardiomyopathy in a young camel (c. dromedarius)
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40002
Model System for Live Imaging of Neuronal Responses to Injury and Repair
Published 2011-11-01“…To visualize the processes of neuronal injury and repair in living animals, we generated reporter mice for bioluminescence and fluorescence imaging bearing the luc (luciferase) and gfp (green fluorescent protein) reporter genes under the control of the murine GAP-43 promoter. …”
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40003
From Serendipity to Precision: Integrating AI, Multi-Omics, and Human-Specific Models for Personalized Neuropsychiatric Care
Published 2025-01-01“…Despite these advancements, traditional methodologies such as animal models and single-variable analyses continue to be used, frequently failing to capture the complexities of human neuropsychiatric conditions. …”
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40004
Wisdom of Landscape Construction of China’s West Lakes in Historical Period and Its Implications
Published 2024-12-01“…The results indicate the following: (1) The overall spatial distribution of WLs is related to China’s history of water conservancy development. (2) The evolution of and functional changes in WLs are influenced by multiple factors such as politics, economy, and culture during different historical periods and are directly related to the will of local administrators. (3) The initial functions of WLs can be categorized into three types, primarily related to urban infrastructure. (4) In terms of spatial relationships, there are four types of spatial relationships between WLs and their water sources and three types of spatial relationships between WLs and cities, forming a common pattern of “Mountains/Hills(–Water)–WL(–Water)–Cities(–Water, River, Sea)” or “WL(–Water)–Cities(–Water, River, Sea)”. (5) The scenery of WLs comprises six elements, including natural basements, water conservancy facilities, human settlements, secularization, landscape architecture, and animal and human activities, all imbued with poetic cultural connotations. …”
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40005
Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque
Published 2017-01-01“…Here, we present a study of a STZ rhesus macaque model of T2DM that utilizes quantitative iTRAQ-based proteomic method. …”
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40006
Planes de vacunación en animales de compañía y sistemas de producción en equinos y bovinos
Published 2024-08-01“… La vacunación desempeña un rol esencial previniendo enfermedades, salvaguardando la salud y el bienestar de la población. …”
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40007
Comparative Evaluation of Bone Repair with Four Different Bone Substitutes in Critical Size Defects
Published 2020-01-01“…The immunostaining showed a decrease in Runx2 intensity in BIO after 40 days, while it increased for LBP (p<0.05). …”
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40008
Impact of Bifidobacterium longum NSP001 on DSS-induced colitis in conventional and humanised mice
Published 2023-07-01“…However, differences between human and animal microbiota may confound the data reproducibility from rodent experiments to clinical trials. …”
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40009
Study of information needs of students in the field of environmental policy
Published 2018-12-01“…The thoughtless, unlimited satisfaction of the growing needs of people has led to an irreversible change in the properties of landscapes, the depletion and loss of minerals, the disappearance of many species of the animal and plant world. Unsolved problems in the field of ecology, at the moment, reflect the reality of the twenty-first century. …”
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40010
Toll-Like Receptor 4 in Bone Marrow-Derived Cells Contributes to the Progression of Diabetic Retinopathy
Published 2014-01-01“…To further elucidate the mechanism of DR, we used bone marrow transplantation to establish reciprocal chimeric animals of TLR4 mutant mice and TLR4 WT mice combined with diabetes mellitus (DM) induction by streptozotocin (STZ) treatment to identify the role of TLR4 in different cell types in the development of the proinflammatory state during DR. …”
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40011
Deficient Autophagy in Microglia Aggravates Repeated Social Defeat Stress-Induced Social Avoidance
Published 2022-01-01“…We found that RSD stress, an animal model of MDD, significantly induced initial autophagic signals followed by increased transcription of autophagy-related genes (Atg6, Atg7, and Atg12) in the PFC. …”
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40012
Differential Micronuclei Induction in Human Lymphocyte Cultures by Imidacloprid in the Presence of Potassium Nitrate
Published 2010-01-01“…Humans are exposed to pesticides as a consequence of their application in farming or their persistence in a variety of media, including food, water, air, soil, plants, animals, and smoke. The interaction of pesticides with environmental factors may result in the alteration of their physicochemical properties. …”
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40013
Inhibition of mutagenic activation of orthoaminoazotoluene increases its carcinogenicity for mouse liver
Published 2016-12-01“…Various mutationally impaired genes are often found in malignant tumors of animals and humans. At the same time, a large number of carcinogens demonstrate positive activity in different in vitro tests for mutagenicity. …”
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40014
Major royal-jelly proteins intake modulates immune functions and gut microbiota in mice
Published 2024-01-01“…The production of IL-1β, IL-6, and IFN-γ was negatively associated with estrogen levels, which were higher in the MRJP-treated animals than in the control group. Analysis of the gut microbiota revealed that feeding mice 250 mg/kg of MRJPs maintained the stability of the natural intestinal microflora of mice. …”
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40015
Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence
Published 2018-01-01“…Eight full papers were entitled to the review; out of those, two studies focused on ethnobotanical surveys, three on animal experiments, one on human trial, and two on in vitro antiviral activities, and one was computational study. …”
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40016
Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis
Published 2016-01-01“…Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models. However, its effect in sepsis is still not investigated. …”
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40017
Studies on the fertilization of mouse eggs in vitro
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40018
Using cortical organoids to understand the pathogenesis of malformations of cortical development
Published 2025-01-01“…One limitation is the difficulty in modeling these disorders, as animal models frequently do not faithfully mirror the human phenotype. …”
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40019
Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis
Published 2025-01-01“…To mimic the effects of vibration, a rat vibration model and a cellular vibration model were used. Animal and cellular models showed that vibration-induced vascular dysfunction while increasing Piezo1 expression. …”
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40020
High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report
Published 2017-01-01“…They directly cause insulin secretory defects in animal and cell culture models and may promote insulin resistance in nondiabetic subjects. …”
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