Enhancement of Neocortical-Medial Temporal EEG Correlations during Non-REM Sleep by Nikolai Axmacher, Christoph Helmstaedter, Christian E. Elger, Juergen Fell

“…Several previous studies in animals and humans suggest that hippocampal-neocortical interactions crucially depend on the state of alertness (i.e., waking state or sleep). …”
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Introducing maximum sustainable yield targets in fisheries could enhance global food security by Christian Elleby, Ignacio Pérez Domínguez, Rasmus Nielsen, Max Nielsen, Ayoe Hoff

“…Maximum sustainable yield management of overfished stocks could increase yields by 10.6 Megatons, equivalent to 12% of total catches and 6% of aquatic animal production in 2022. This would alleviate the need for aquaculture expansion by an equivalent of 3 years of growth in the aquaculture sector at its current level, and reduce meat and feed demand. …”
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Epigenetic Modifications and Potential New Treatment Targets in Diabetic Retinopathy by Lorena Perrone, Carmela Matrone, Lalit P. Singh

“…As with other diabetic complications, diabetic retinopathy (DR) is characterized by the metabolic memory, which has been observed both in DR patients and in DR animal models. Evidences have provided that after a period of poor glucose control insulin or diabetes drug treatment fails to prevent the development and progression of DR even when good glycemic control is reinstituted (glucose normalization), suggesting a metabolic memory phenomenon. …”
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Microgravity, Stem Cells, and Cancer: A New Hope for Cancer Treatment by Uğur Topal, Cihan Zamur

“…Although studies have been carried out in a simulated microgravity environment in cell culture lines, there are few animal experiments or true microgravity studies. Cancer remains one of the most significant problems worldwide. …”
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Tospoviruses (Family Bunyaviridae, Genus Tospovirus) by Scott Adkins, Tom Zitter, Tim Momol

“…The causal agent was designated TSWV, and considered to be the sole member of the tomato spotted wilt group of plant viruses until the early 1990s. At this time, the identification and characterization of several similar viruses, including Impatiens necrotic spot virus (INSV), led to the creation of the plant-infecting Tospovirus genus within the Bunyaviridae family, a large group of predominantly animal-infecting viruses. …”
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Recurrent neural networks with transient trajectory explain working memory encoding mechanisms by Chenghao Liu, Shuncheng Jia, Hongxing Liu, Xuanle Zhao, Chengyu T. Li, Bo Xu, Tielin Zhang

“…Besides activity patterns resembling animal recordings and retained versatility to variable encoding time, TRNNs show better performance in delayed choice and spatial memory reinforcement learning tasks. …”
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SELECTION FOR CATATONIA: EFFECT ON THE SEXUAL FUNCTION AND ESTROUS CYCLE SYNCHRONIZATION by D. V. Klochkov, T. A. Alekhina

“…A statistically significant synchronization of estrous cycles is observed in GC rats kept in standard cages, five to seven animals per cage. It includes a larger number of matches of individual estrus phases to form a group estrus phase of their 4–5-day long estrous cycle. …”
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Novel cisplatin-magnetoliposome complex shows enhanced antitumor activity via Hyperthermia by M. Carmen Jiménez-López, Ana Carolina Moreno-Maldonado, Natividad Martín-Morales, Francisco O’Valle, M. Ricardo Ibarra, Gerardo F. Goya, Ignacio J. Molina

“…Therefore, our approach of magnetic hyperthermia plus CDDP-ML significantly enhances in vitro cell death and in vivo survival of treated animals.…”
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Designing a Long Acting Erythropoietin by Fusing Three Carboxyl-Terminal Peptides of Human Chorionic Gonadotropin β Subunit to the N-Terminal and C-Terminal Coding Sequence by Fuad Fares, Avri Havron, Eyal Fima

“…The therapeutic efficacy of EPO-CTP analog needs to be established in higher animals and in human clinical trials.…”
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Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche by Alejandro Luarte, Luis Federico Bátiz, Ursula Wyneken, Carlos Lafourcade

“…These novel approaches should be examined in cellular and animal models to provide better, more effective, and specific therapeutic tools in the future.…”
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Brain targeting based nanocarriers loaded with resveratrol in Alzheimer's disease: A review by Cyrus Jalili, Amir Kiani, Mohammadreza Gholami, Fariborz Bahrehmand, Sajad Fakhri, Somayeh Kakehbaraei, Seyran Kakebaraei

“…Regarding the urgent need for the development of novel treatments for neurodegenerative diseases, researchers have recently perused the function of natural phytobioactive combinations, such as resveratrol (RES), in vivo and in vitro (animal models of AD). Investigations have shown the neuroprotective action of RES. …”
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Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance by Alessia Fidoamore, Loredana Cristiano, Andrea Antonosante, Michele d’Angelo, Erica Di Giacomo, Carlo Astarita, Antonio Giordano, Rodolfo Ippoliti, Elisabetta Benedetti, Annamaria Cimini

“…An altered vascular network determines irregular blood flow, so that tumor cells spread rapidly beyond the diffusion distance of oxygen in the tissue, with the consequent formation of hypoxic or anoxic areas, where the bulk of glioblastoma stem cells (GSCs) reside. …”
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The effects of local and systemic inflammatory status on iron metabolism and lipid profile in calves by Uğur Aydoğdu, İbrahim Yurdakul

“…After routine clinical examinations of all the animals were performed, 8 ml of blood was taken for blood analysis and biochemical analyses were performed.…”
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Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis by Donna M. Sosnoski, Venkatesh Krishnan, William J. Kraemer, Courtenay Dunn-Lewis, Andrea M. Mastro

“…In this study, we examined levels of MCP-1, IL-6, KC, MIP-2, VEGF, MIG, and eotaxin in femurs of athymic nude mice inoculated via intracardiac injection with MDA-MB-231GFP human metastatic breast cancer cells, MDA-MB-231BRMS1GFP, a metastasis suppressed variant, or PBS. Animals were euthanized (day 3, 11, 19, 27 after injection) to examine femoral cytokine levels at various stages of cancer cell colonization. …”
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Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression by Rachel Caldwell, Yan-Xia Lin, Ren Zhang

“…The research aims to apply quantile regression techniques for statistical analysis of coding and noncoding sequence length and gene expression data in the plant, Arabidopsis thaliana, and fruit fly, Drosophila melanogaster, to determine if a relationship exists and if there is any variation or similarities between these species. …”
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Secondary motor cortex tracks decision value during the learning of a non-instructed task by Elisabete Augusto, Vladimir Kouskoff, Nicolas Chenouard, Margaux Giraudet, Léa Peltier, Aron de Miranda, Alexy Louis, Lucille Alonso, Frédéric Gambino

“…Summary: Optimal decision-making depends on interconnected frontal brain regions, enabling animals to adapt decisions based on internal states, experiences, and contexts. …”
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Scorpion Venom and the Inflammatory Response by Vera L. Petricevich

“…The clinical signs and symptoms observed in humans and experimental animals are related with an excessive systemic host inflammatory response to stings and stings, respectively. …”
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Inhibitory Effect of Aconitine on Colorectal Cancer Malignancy via Inducing Apoptosis and Suppression of Cell Motion by Xuehui Li, Jianglin Hu, Duan Tong, Taotao Yang, Ming Deng

“…Animal experiments were performed to further elucidate aconitine’s effect on CRC tumorigenesis. …”
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Causes and solutions for fruit and vegetable waste: a participatory approach with Romanian farmers for sustainable agriculture by Ruxandra Malina Petrescu-Mag, Dacinia Crina Petrescu, Iulia Ajtai, Carmen Andreea Roba, Oana Adriana Gica, Lucian Cuibus, Ancuta Tenter, Valentin Toader, Adina Letitia Negrusa, Nicoleta Bican-Brișan

“…Farmers are the most important stakeholders in minimizing FV waste in primary production, and any intervention must consider their attitudes and perspectives. …”
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Hypertension in Metabolic Syndrome: Vascular Pathophysiology by Yolanda Mendizábal, Silvia Llorens, Eduardo Nava

“…Next we discuss the importance of perivascular adipose tissue and the role of adipokines that possess vasoactive properties. Finally, animal models used in the study of vascular function of metabolic syndrome are reviewed. …”
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