Prion protein promotes copper toxicity in Wilson disease by Raffaella Petruzzelli, Federico Catalano, Roberta Crispino, Elena V. Polishchuk, Mariantonietta Elia, Antonio Masone, Giada Lavigna, Anna Grasso, Maria Battipaglia, Lucia Vittoria Sepe, Banu Akdogan, Quirin Reinold, Eugenio Del Prete, Diego Carrella, Annalaura Torella, Vincenzo Nigro, Enrico Caruso, Nicole Innocenti, Emiliano Biasini, Ludmila V. Puchkova, Alessia Indrieri, Ekaterina Y. Ilyechova, Pasquale Piccolo, Hans Zischka, Roberto Chiesa, Roman S. Polishchuk

“…Suppression of PrP significantly reduces Cu toxicity in cell and animal models of Wilson disease. These findings highlight the critical regulatory role of PrP in copper metabolism and open new avenues for exploring the therapeutic potential of PrP suppression in Wilson disease.…”
Get full text

Invasion and ecological impact of the biofouling tube worm Hydroides elegans (Polychaeta: Serpulidae) in Korean coastal waters by Sang Lyeol Kim, Ok Hwan Yu

“…Biofouling, the colonization of submerged surfaces by organisms including microorganisms, plants, algae, and animals, involves both natural and artificial environments. …”
Get full text

Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal by Diego E. Hernandez, Andrei Ciuparu, Pedro Garcia da Silva, Cristina M. Velasquez, Benjamin Rebouillat, Michael D. Gross, Martin B. Davis, Honggoo Chae, Raul C. Muresan, Dinu F. Albeanu

“…Abstract While animals readily adjust their behavior to adapt to relevant changes in the environment, the neural pathways enabling these changes remain largely unknown. …”
Get full text

Analiza substytucji pracy ludzkiej kapitałem w towarowych gospodarstwach rolnych w pierwszych latach członkostwa Polski w UE by Anna Nowak, Ewa Wójcik

“…Oddziaływał on w gospodarstwach w pierwszych latach członkostwa Polski w UE nieco mniej skutecznie aniżeli po pięciu latach tj. w 2009r. Celowa jest substytucja pracy ludzkiej strumieniem kapitału we wszystkich gospodarstwach przyjmujących jako kryterium celu działalności produkcję gospodarstwa rolnego.…”
Get full text

Comparison of some methods used for estimation of heritability by Tamer Çağlayan, Şeref İnal

“…In this investigation, 1647 chicks at 6-weeks old were obtained from 20 male and 100 female quail and used as the animal material. After correcting the body weights (or sex effect, heri t abilities were estimated for each method. …”
Get full text

The ADF/Cofilin-Pathway and Actin Dynamics in Podocyte Injury by Beina Teng, Alexander Lukasz, Mario Schiffer

“…Cofilin knockdown and knockout animal models show dysfunction of glomerular barrier and filtration with foot process effacement and loss of secondary foot processes. …”
Get full text

Multifunctional health-promoting effects of oolong tea and its products by Shuzhen Wang, Ting Zeng, Shuang Zhao, Yu Zhu, Changchun Feng, Jianfeng Zhan, Shiming Li, Chi-Tang Ho, Alexander Gosslau

“…These promising studies mainly gained from animal studies might broaden the consumption and usage of the phenolic-enriched oolong tea and its products in food and pharmaceutical industries. …”
Get full text

Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches by Vasilis Paspaliaris, George Kolios

“…This review is focused on the current views regarding the implication of the stem cells in the cellular and physiologic mechanisms of osteoporosis and discusses data obtained from stem cell-based therapies of osteoporosis in experimental animal models and the possibility of their future application in clinical trials.…”
Get full text

Tumor cells escape immunosurveillance by hampering LFA-1 by Shishir Upadhyay, Lewis Murugu, Lena Svensson, Lena Svensson

“…Moreover, we discuss therapeutic strategies targeting LFA-1, including inhibitors tested in laboratory studies and animal models, highlighting their potential as anticancer interventions and the need for further research to evaluate their clinical utility.…”
Get full text

Analiza substytucji pracy ludzkiej kapitałem w towarowych gospodarstwach rolnych w pierwszych latach członkostwa Polski w UE by Anna Nowak, Ewa Wójcik

“…Oddziaływał on w gospodarstwach w pierwszych latach członkostwa Polski w UE nieco mniej skutecznie aniżeli po pięciu latach tj. w 2009r. Celowa jest substytucja pracy ludzkiej strumieniem kapitału we wszystkich gospodarstwach przyjmujących jako kryterium celu działalności produkcję gospodarstwa rolnego.…”
Get full text

METHOD FOR FMD VIRUS 146S COMPONENT CONCENTRATION DETERMINATION WITH REAL-TIME REVERSE TRANSCRIPTION – POLYMERASE CHAIN REACTION IN VACCINE RAW MATERIALS by M. I. Doronin, A. M. Timina, D. A. Lozovoy, V. A. Starikov, D. V. Mikhalishin, N. N. Medvedeva, А. V. Borisov

“…It has been experimentally proven that the quantity of the 146S component determined by the real-time RT-PCR method using developed regression model and contained in the inoculation dose of FMD vaccine confers protection to the vaccinated animals against generalized FMD of A, O, Asia-1 types. rtRT-PCR method is highly sensitive and allows rapid and highly reliable estimation of  the 146S antigen concentration in FMD vaccine. …”
Get full text

Bilateral Neuropathy of Primary Sensory Neurons by the Chronic Compression of Multiple Unilateral DRGs by Ya-Bin Xie, Huan Zhao, Ying Wang, Kai Song, Ming Zhang, Fan-Cheng Meng, Yu-Jie Yang, Yang-Song He, Fang Kuang, Si-Wei You, Hao-Jun You, Hui Xu

“…To mimic multilevel nerve root compression and intervertebral foramina stenosis in human, we established a new animal model of the chronic compression of unilateral multiple lumbar DRGs (mCCD) in the rat. …”
Get full text

Myocardial Regeneration via Progenitor Cell-Derived Exosomes by Janita A. Maring, Christien M. Beez, Volkmar Falk, Martina Seifert, Christof Stamm

“…The body of evidence on beneficial exosome-mediated effects in animal models of heart diseases is rapidly growing. …”
Get full text

Exploring the Protective Effects of Xueshuantong Injection on Central Retinal Vein Occlusion by Qiang Chen, Jing Zhang, Xin-Yu Liu, Kai Xu, Hui-Yi Guo, Ya-Min Li, Yu-Qing Guo, Li-Na Liang

“…Materials and Methods: CRVO was induced in rabbits and rats by laser photocoagulation. The animals were then treated with different doses of XST or lyophilized XST (L). …”
Get full text

Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice by Jing Geng, Xiaoliang Zhang, Yanjie Guo, He Wen, Dong Guo, Qi Liang, Siying Pu, Ying Wang, Mingchuan Liu, Zhelong Li, Wei Hu, Xue Yang, Pan Chang, Lang Hu, Yan Li

“…Of note, the current findings are based on animal experiments, the generalizability of these findings beyond this specific diet and mouse strain remains to be further explored.…”
Get full text

Structural Analysis of Amylin and Amyloid β Peptide Signaling in Alzheimer’s Disease by Longsheng Xie, Christopher Lockhart, Steven R. Bowers, Dmitri K. Klimov, Mohsin Saleet Jafri

“…Recent studies have demonstrated that amylin-based peptides can reduce the symptoms of Alzheimer’s disease in animal models. Replica exchange molecular dynamics simulation machine learning, as well as other computational analyses, were applied to improve the understanding of the amino acid residues in these amylin-based peptides. …”
Get full text

Management of Nematodes with Cowpea Cover Crops by Koon-Hui Wang, Robert McSorley

“…Date first printed: August 2004. ENY-712/IN516: Management of Nematodes with Cowpea Cover Crops (ufl.edu) …”
Get full text

Differences in spatiotemporal dynamics for processing specific semantic categories: An EEG study by Trang Thi Le, Do Anh Quan Luong, Hyosung Joo, Dongseok Kim, Jihwan Woo

“…This study investigates spatiotemporal neural representation during the perception of semantic words related to faces, numbers, and animals using electroencephalography. Source‐level analysis focuses on contrasting neural responses to different semantic categories. …”
Get full text

Estrous Synchronization and Fixed-Time Artificial Insemination by Vitor R. G. Mercadante, Darren D. Henry, Francine M. Ciriaco, Pedro L. P. Fontes, Nicky Oosthuizen, G. Cliff Lamb

“…Cliff Lamb, and published by the UF Department of Animal Sciences, January 2016. …”
Get full text

The Place of Women in Environmental Management and Sustainability in Nigeria by Umezurike J. Ezugwu, Enyimba Maduka, Emmanuel E. Etta, Samuel Aloysius Ekanem, Ushie Thomas Egaga

“…We will also show the negative impacts of these forcefully assigned female duties on the climate, and how this leads to pollution, which in turn, obstructs the biospheres (plant and animal species). Using the principle of complementarity, the paper insists on the need to eradicate all socio-culturally perceived superlative attributes of distinction between human society and environment or masculinity and femininity. …”
Get full text