Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease by G. D’Arcangelo, D. Grossi, M. Racaniello, A. Cardinale, A. Zaratti, S. Rufini, A. Cutarelli, V. Tancredi, D. Merlo, C. Frank

“…Progressive neurological deterioration and insurgence of symptoms like ataxia, seizure, and cognitive decline until severe dementia are pathognomonic features of the disease. …”
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Could Proteomic Research Deliver the Next Generation of Treatments for Pneumococcal Meningitis? by U. R. Goonetilleke, S. A. Ward, S. B. Gordon

“…Using proteomic techniques and bioinformatics, the protein content of cerebrospinal fluid can be examined in great detail. Animal models have added greatly to our knowledge of possible mechanisms and shown that hippocampal apoptosis and cortical necrosis are distinct mechanisms of neuronal death. …”
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Natural Climate Variability Can Influence Cyanobacteria Blooms in Florida Lakes and Reservoirs by Karl E. Havens, Mark V. Hoyer, Edward J. Phlips

“…They look awful, smell bad, and can poison fish and other animals in the water. To help resource managers considering costly remediation projects or evaluating the effectiveness of nutrient reduction strategies to manage the problem, this 7-page fact sheet presents the results from 15 years of studies observing three large, nutrient-rich lakes in Florida (Lake Harris, Lake George, and Lake Okeechobee) to study the relationship between rainfall and cyanobacteria blooms and learn causes of year-to-year bloom variability. …”
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Prospects of Nanobiomaterials for Biosensing by Ravindra P. Singh

“…The biosensors using smart nanomaterials have applications for rapid, specific, sensitive, inexpensive, in-field, on-line and/or real-time detection of pesticides, antibiotics, pathogens, toxins, proteins, microbes, plants, animals, foods, soil, air, and water. Thus, biosensors are excellent analytical tools for pollution monitoring, by which implementation of legislative provisions to safeguard our biosphere could be made effectively plausible. …”
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Assessment and incorporation of in vitro correlates to pharmacokinetic outcomes in antibody developability workflows by Tushar Jain, Bianka Prinz, Alexander Marker, Alexander Michel, Katrin Reichel, Valerie Czepczor, Sylvie Klieber, Wei Sun, Sagar Kathuria, Sevim Oezguer Bruederle, Christian Lange, Lena Wahl, Charles Starr, Alessandro Masiero, Lindsay Avery

“…This can minimize the need for extensive early in vivo PK characterization, thereby reducing animal usage and optimizing resources. In this study, we recommend bolstering classical developability workflows with in vitro measures correlated with PK. …”
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Mining the Virgin Land of Neurotoxicology: A Novel Paradigm of Neurotoxic Peptides Action on Glycosylated Voltage-Gated Sodium Channels by Zhirui Liu, Jie Tao, Pin Ye, Yonghua Ji

“…Sodium channel-specific neurotoxic toxins, a family of long-chain polypeptides originated from venomous animals, are found to potentially share the binding sites adjacent to glycosylated region on VGSCs. …”
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Trichromacy is insufficient for mate detection in a mimetic butterfly by Andrew Dang, Gary D. Bernard, Furong Yuan, Aide Macias-Muñoz, Ryan I. Hill, J. P. Lawrence, Aline Giselle Rangel Olguin, Armando Luis-Martínez, Sean P. Mullen, Jorge Llorente-Bousquets, Adriana D. Briscoe

“…Abstract Color vision is thought to play a key role in the evolution of animal coloration, while achromatic vision is rarely considered as a mechanism for species recognition. …”
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Systematic review on mitigation of food loss and waste in the milk supply chain by Romadlon Fauzan, Wan Ahmad Wan Nurul Karimah, Shamsuddin Alina

“…The review was divided into three themes based on the causes of food loss and waste: animal health, actor performance, and managerial approach. …”
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Contemplation on Development of Traditional Chinese Medicine Rehabilitation Science by Xiaodong FENG

“…For example, <italic>Huangdi Neijing</italic> emphasizes regulating mental states and body to enhance the ability of resistance to disease, the Five-Animal Exercises created by Huatuo can prevent disease and build body, acupuncture, moxibustion and medicine ironing also appear in the clinical and health literature of TCM. …”
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Serotonin and Its Receptor as a New Antioxidant Therapeutic Target for Diabetic Kidney Disease by Yu Yang, Hui Huang, Zheng Xu, Jun-kai Duan

“…We conclude that 5-HTR is a potential therapeutic target for treating DKD, as it has been successfully applied in animal models and has currently being investigated in randomized and controlled clinical trials.…”
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Impact of Hop Residue Reuse on the Chemical and Sensory Properties of Craft Beer by Cesar I. Mejia-Llontop, Carlos E. Tirado-Rodríguez, Alanis Acosta-Baca, Maylee Aguayo-Flores, Manuel Ascate-Pasos, Carmen Ayala-Jara, Gilbert Rodriguez, Eudes Villanueva, Elza Aguirre

“…A significant amount of hop residue is generated in the dry-hop brewing process that cannot be reused due to bittering residues that disqualify them as animal feed or other products. The purpose of this research was to reuse four varieties of hop waste (Citra, Mosaic, Hallertau Blanc, and Mandarina Bavaria) through a repalletization process with the objective of integrating them into a new craft beer brewing process. …”
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Efficacy of Sakacin on Selected Food Pathogenic Microorganisms Isolated from Fermented Milk Products by SSD Mohammed, D Damisa, TV Balogu, E Bala

“…The LAB can serve as probiotics, which are products aimed at delivering living, potentially beneficial bacterial cells to the gut ecosystem of humans and other animals. © JASEM Keywords: Inhibition, sakacin, De Man Rogosa Sharpe, broth, morphology …”
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Origens da Religião e da Moral by Élisée Reclus

“…Besides that, emphasizes that the reproduction of irrationalities such as those that promoted the emergence of rituals of sacrifice of people and animals are important elements for understanding the development and consolidation of different religions and these irrationalities were aligned with the interests related to the maintenance of power…”
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Peripheral Nerve Repair with Cultured Schwann Cells: Getting Closer to the Clinics by Maria Carolina O. Rodrigues, Antonio Antunes Rodrigues, Loren E. Glover, Julio Voltarelli, Cesario V. Borlongan

“…Experimental studies provide evidence of functional, histological, and electromyographical improvement following transplantation of bone-marrow-derived cells in animal models of peripheral nerve injury. This paper focuses on this new therapeutic approach highlighting its direct translational and clinical utility in promoting regeneration of not only acute but perhaps also chronic cases of peripheral nerve damage.…”
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A Review: Farmers' Local Wisdom on Natural Resources by Zuhud Rozaki, Oki Wijaya, Khamsing Keothoumma, Emil Salim

“…Natural resources, especially in terms of soil, water, plant and animal diversity, vegetation cover, climate, and ecosystem services, are fundamental for agricultural systems' structure and function. …”
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12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation by Alexa R. Lindley, Margaret Crapster-Pregont, Yanjun Liu, Douglas A. Kuperman

“…Interleukin-13 increases expression of the arachidonic acid-metabolizing enzyme, 15-lipoxygenase-1, in a variety of cell types. 15-lipoxygenase-1 is dramatically elevated in the airways of subjects with asthma. Studies in animals indicate that 15-lipoxygenase-1 contributes to the development of allergic airway inflammation but is protective in some other forms of inflammation. …”
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« The arrested step », Nightwood de Djuna Barnes : « Une image est une halte que fait l’esprit entre deux incertitudes » by Christiane Guillois

“…In her search for the universal in this animal aspiring to transcendence and now passing through its human stage, she probes the bodies of her characters with a doggedness that leads to near-disintegration. …”
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The Impact of Parent-Child Relationships on the Emotional State of Children with Cancer Undergoing Long-Term Treatment by Yu.P. Zamyshliaeva, Yu.E. Kurtanova

“…Markovskaya, family sociogram, projective technique &ldquo;Non-existent animal&rdquo;, &ldquo;Train&rdquo; by S.V. Velieva, anxiety test by A.M. …”
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TOXICOLOGIC CHARACTERISTICS OF THE PREVENTIVE IODINE-CONTAINING PREPARATION “VANGTSEYOD” by T. V. Kruchinkina, Yu. A. Gavrilov, G. A. Gavrilova

“…The Amur Oblast belongs to biogeochemical province with low contents of iodine in the soil, water and air, which leads to the thyroid gland disorders in animals, weakened immunity system and, consequently, to the increased sensitivity to diseases. …”
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Using of seaweed extract in diets of japanese quails: 2. the effects of seaweed extract on egg yield by Fatma İnal, Behiç Coşkun, M. Kemal Çiftçi, Nurettin Gülşen

“…In the flrst trial, total 72 female Japanese quails aged 5 weeks were used. During 8 weeks. the animals fed diets contalnlng 0, 0.01, 0. 1 and 1 % Maxicrop extracted from Ascophyllum nodosum. …”
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