Food groups, macronutrient intake and objective measures of total carotenoids and fatty acids in 16-to-24-year-olds following different plant-based diets compared to an omnivorous... by Synne Groufh-Jacobsen, Christel Larsson, Isabelle Mulkerrins, Dagfinn Aune, Anine Christine Medin

“…No difference was found between groups in mean intake (g/d, g/MJ) of any of the confectionary foods or sweet pastries, beverages (sugar-sweetened, non-sugary, alcoholic), or salted snacks, neither in g/MJ of convenience foods. …”
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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity by Congcong Zhang, Anja Waldmann, Winfried S Wels, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Nina Müller, Pranav Oberoi

“…In an immunocompetent mouse glioblastoma model mimicking low or absent NKG2DL expression, the combination of NKAR-NK-92 cells and NKAB-ErbB2 effectively suppressed outgrowth of ErbB2-positive tumors, resulting in treatment-induced endogenous antitumor immunity and cures in the majority of animals.Conclusions Our results demonstrate that combining an NKAB antibody with effector cells expressing an activating NKAR receptor represents a powerful and versatile approach to simultaneously enhance tumor antigen-specific as well as NKG2D-CAR and natural NKG2D-mediated cytotoxicity, which may be particularly useful to target tumors with heterogeneous target antigen expression.…”
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Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China. by Huan Yun, Liang Sun, Qingqing Wu, Geng Zong, Qibin Qi, Huaixing Li, He Zheng, Rong Zeng, Liming Liang, Xu Lin

“…<h4>Background</h4>Animal studies suggest vital roles of sphingolipids, especially ceramides, in the pathogenesis of type 2 diabetes (T2D) via pathways involved in insulin resistance, β-cell dysfunction, and inflammation, but human studies are limited. …”
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The use of bacterial culture for Leptospirosis di- agnosis in female water buffaloes by Rosaura Pérez-Gil, Oriana Gavidia, Juan Torres

“…For this, 18 blood samples (16 females and two males) were extracted by puncture of the jugular vein, and these were allowed to coagulate to obtain the serum and urine samples from 2 female buffaloes, one male buffalo, and semen from 2 other animals, were collected. …”
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Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation by Liu H, Mei M, Zhong H, Lin S, Luo J, Huang S, Zhou J

“…And then, we adopted the quantitative real-time PCR (RT-qPCR) assay to validate the hub genes among several CKD animal models. Furthermore, we constructed a competitive endogenous RNA (ceRNA) network for the hub genes utilizing the ENCORI and miRDB databases, while also calculating Spearman correlation coefficients. …”
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Influence of urokinase gene-knockout in C57BL/6-PlautmI. IBugThisPlau6FDhu/GFDhu mice on growth factors in malignant melanoma by E. M. Frantsiyants, I. V. Kaplieva, I. V. Neskubina, V. A. Bandovkina, L. K. Trepitaki, E. I. Surikova, N. D. Cheryarina, L. A. Nemashkalova, N. S. Lesovaya

“…Lower levels of FGF‑21 in tumors (males – by 5.3 times, females – by 18.4 times), perifocal tissues (males – by 9.6 times, females – by 8,5 times) and skin (males – by 6.7 times, females – by 3.3 times) in uPA gene-knockout animals could be due to the IGF‑1 growth, as their reciprocal interaction is known. …”
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Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma by Jie Mao, Shu-Ze Zhang, Peng Du, Zhi-Bin Cheng, Huan Hu, Shi-Yao Wang

“…To detect the tumor samples of 122 patients with colorectal carcinoma after surgery, analyze the effect of probiotics on enhancing tumor-infiltrating CD8+T cells to inhibit colorectal carcinoma, and further verify the mechanism of probiotics on enhancing the antitumor immune response of CD8+T cells through animal experiments. Results. The results of immunohistochemistry showed that the proportion of CD8+T cells in the patients treated with probiotics before surgery was increased significantly than that in other patients (P=0.033). …”
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The dual anti-inflammatory and anticoagulant effects of Jianpi Huashi Tongluo prescription on Rheumatoid Arthritis through inhibiting the activation of the PI3K/AKT signaling pathw... by Fanfan Wang, Fanfan Wang, Jian Liu

“…Lastly, a co-culture system of RA patient-derived peripheral blood mononuclear cells (RA-PBMCs) and vascular endothelial cells (VECs) was established to mimic the in vivo microenvironment, and the anti-inflammatory and anticoagulant mechanisms of XFC were validated in vitro.ResultsData mining analysis revealed abnormally elevated levels of inflammatory and coagulation markers such as fibrinogen (FBG), erythrocyte sedimentation rate (ESR), high-sensitivity C-reactive protein (Hs-CRP), and rheumatoid factor (RF) in RA patients (p &lt; 0.001), and emphasized the close correlation between XFC treatment and the improvement of these markers including Hs-CRP, ESR, and RF (confidence &gt;60% and lift &gt;1). Animal experimental data indicated that XFC effectively reduced the levels of inflammatory and coagulant markers (IL-6, D-D, FBG, PAF, VEGF, and TF) in adjuvant-induced arthritis (AA) rats while enhancing the expression of anti-inflammatory factors (IL-10) (p &lt; 0.05). …”
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Combination Fractional Carbon Dioxide Laser Treatment and Bone Marrow Mesenchymal Stem Cell Therapy Enhances the Treatment of Skin Photoaging in a Murine Model System by Li L, He Z, Yu C, Zhang C, Yu Y, Li Y, Xu X

“…Samples of dorsal skin from these animals were subjected to hematoxylin and eosin staining or Masson’s trichrome staining. …”
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Association Between Weight-Adjusted Waist Index and Cognitive Function in Older Adults Without Diabetes: A Cross-Sectional Study by Wang Q, Yin Y, Liu W, Li L, Wang Z, Tian Y, Fan J

“…Qing Wang,1,&ast; Yishan Yin,2,&ast; Wei Liu,3,&ast; Lingyu Li,1 Zhen Wang,1 Yue Tian,1 Jing Fan1 1Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China; 2Department of Orthopedics, The Armed Police Forces Hospital of Shandong, Jinan, Shandong, 250000, People’s Republic of China; 3Department of Emergency Critical Care Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jing Fan, Department of Laboratory Medicine, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China, Email sddzfanjing@163.comBackground: This study investigates the correlation between the weight-adjusted waist index (WWI) and cognitive performance in the senior American population, focusing on those without diabetes from 2011 to 2014.Methods: We analyzed data from the 2011– 2012 and 2013– 2014 National Health and Nutrition Examination Surveys (NHANES), focusing on non-diabetic participants aged 60 and older who completed cognitive tests: Establish a Registry for Alzheimer’s disease (CERAD), the Animal Fluency test (AFT), and Digit Symbol Substitution test (DSST). …”
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Respuesta de una comunidad de pajonal (Amelichloa brachychaeta) al pastoreo frecuente y de altas cargas en la región semiárida central de Argentina by Priscilia Lamela Arteaga, Carla Suárez, Daniel Estelrich

“…En un potrero con bosque de Neltuma caldenia con pajonal, se definieron 4 tratamientos de carga animal para el seguimiento del pajonal durante un año. …”
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Segmentation of Dynamic Total-Body [18F]-FDG PET Images Using Unsupervised Clustering by Maria K. Jaakkola, Maria Rantala, Anna Jalo, Teemu Saari, Jaakko Hentilä, Jatta S. Helin, Tuuli A. Nissinen, Olli Eskola, Johan Rajander, Kirsi A. Virtanen, Jarna C. Hannukainen, Francisco López-Picón, Riku Klén

“…However, PET image segmentation in multiorgan level is much less studied due to the available total-body data being limited to animal studies. Now, the new PET scanners providing the opportunity to acquire total-body PET scans also from humans are becoming more common, which opens plenty of new clinically interesting opportunities. …”
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THE CHARACTERISTICS OF MIRNA BINDING SITES IN MRNA OF ZFHX3 GENE AND ITS ORTHOLOGS by A. М. Kondybayeva, A. N. Akimniyazova, S. U. Kamenova, A. Т. Ivashchenko

“…In the orthologous proteins of 36 animal species the length of polyGlu varied from 27 Glu to 33 Glu. …”
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Prevalence of dyslipidemia and its influencing factors among adult residents in Hebei province: a cross-sectional survey by Qianyu LI, Yajing CAO, Lijuan TANG, Yuhuan LIU, Xiaoying LU, Qi QI, Shifan WANG, Xiaoli LIU, Ze CUI

“…Unconditional multivariate logistic regression analysis showed that among adult residents, age ≥ 25 years, current smoking, overweight, obesity, central obesity, body fat percentage ≥ 27.2%, and basal metabolic rate ≥ 1 504 kcal were risk factors for dyslipidemia, whereas female gender, rural residence, and sedentary time of 2 – 4 hours per day were protective factors against dyslipidemia; age ≥ 25 years, college education or higher, current smoking, central obesity, and body fat percentage ≥ 37.9% were risk factors for hypercholesterolemia, whereas a basal metabolic rate of 1 199 – 1 503 kcal was a protective factor; age 25 – 64 years, current smoking, consumption of animal and poultry meat 300 – 500 g per week, overweight, obesity, central obesity, and body fat percentage ≥ 27.2% were risk factors, whereas female gender was a protective factor for hypertriglyceridemia; age ≥ 25 years, central obesity, sedentary time ≥ 2 hours per day, and body fat percentage ≥ 37.9% were risk factors, whereas basal metabolic rate 1 199 – 1 503 kcal was a protective factor for hyper-LDL-C; ethnic minority, current smoking, overweight, obesity, central obesity, physical inactivity, body fat percentage 33.0% – 37.8%, and basal metabolic rate ≥ 1 327 kcal were risk factors, whereas being female, aged 45 – 54 years, living in rural areas, drinking alcohol, consuming livestock and poultry meat > 500 g per week, and being sedentary for ≥ 2 hours per day were protective factors for hypo-HDL-C. …”
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Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model by Sang-A. Oh, Song-I. Seol, Dashdulam Davaanyam, Seung-Woo Kim, Ja-Kyeong Lee

“…Triphenyltetrazolium chloride (TTC) staining revealed rapid but progressive expansion of the infarct area in the PTS model, commencing within 1 h and continuing until 24 h. Concomitant with this, peripheral neutrophils isolated following PTS exhibited progressive NETosis, particularly intravascular NETosis. …”
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Infestation and damage status assessment of white mango scale (Aulacaspis tubercularis) insect at boloso sore and boloso bombe districts of Wolaita Zone South Ethiopia by Andualem Alemayehu, Zerhun Tomas

“…Several concoctions made from ash, soap and goat urine were mixed and sprayed on infested mango fruit leaves and twigs. …”
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Respuesta de una comunidad de pajonal (Amelichloa brachychaeta) al pastoreo frecuente y de altas cargas en la región semiárida central de Argentina by Priscilia Lamela Arteaga, Carla Suárez, Daniel Estelrich

“…En un potrero con bosque de Neltuma caldenia con pajonal, se definieron 4 tratamientos de carga animal para el seguimiento del pajonal durante un año. …”
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Effect of stocking density on growth performance of African catfish Clarias gariepinus and water spinach Ipomoea aquatica in aquaponics systems with the addition of AB mix nutrient by Wiyoto Wiyoto, Ridwan Siskandar, Ratih Kemala Dewi, Wida Lesmanawati, Muhammad Arif Mulya, Julie Ekasari

“…Tujuan dari penelitian ini untuk mengevaluasi performa pertumbuhan lele dan kangkung dalam sistem akuaponik dengan penambahan nutrisi AB mix dan pada padat tebar ikan yang berbeda. …”
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Evaluación del expeller de soja en dietas de cerdos en recría y engorde by Vanina MURCIA, A.J. PORDOMINGO, A.B. PORDOMINGO, Raul FRANCO

“…Se obtuvieron en promedio un 40% de AGS, 46% de AGMI y 14% AGPI y un 42% AGS, 37,21% AGMI y un 19,79% AGPI para la grasa intramuscular del LD y la grasa subcutánea, respectivamente. …”
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Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-&beta;-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study by Zucca G, Vigani B, Valentino C, Ruggeri M, Marchesi N, Pascale A, Giovilli G, Malavasi L, Sandri G, Rossi S

“…Further studies about the safety and the effectiveness of the intravitreal injection of NHs@NAR/β-CD will be performed on a diabetic animal model. Keywords: polyelectrolyte complexation, cellular uptake, inclusion complex, antioxidant properties, intravitreal administration…”
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