Candidate vaccine construction against tick-born encephalitis based on hybrid recombinant flagG-protE-protein by P. A. Belavin, D. A. Kunyk, E. V. Protopopova, V. B. Loktev, E. V. Deineko

“…Our data indicate that the antigenic structure of recombinant protE­protein can be changed under the influence of the flagellin domain, which in turn can lead to the unavailability of some antigenic determinants. This fact must be taken into account when constructing recombinant molecules with antigenic properties. …”
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The Use of Granular Cyclopentanone as Alternative to Artificial Source of Carbon Dioxide in Improved Passive Outdoor Host Seeking Device (POHD) by Stella T. Kessy, Bruno A. Nyundo, Ladslaus L. Mnyone, Issa N. Lyimo

“…Several odor-baited devices are in the pipeline; however, their scale-up against residual malaria transmission, particularly in resource poor areas, is limited by the unavailability of reliable sources of CO2 and reliance on electrical power sources among other factors. …”
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Prospective Application of the Erythrocyte Sedimentation Rate (ESR) as a Possible Inflammatory Marker in Feline Patients by Eleonora Gori, Anna Pasquini, Saverio Paltrinieri, George Lubas, Carlo Militello, Daniela Diamanti, Carlo Carletti, Marianna Pantoli, Veronica Marchetti

“…The application of the erythrocyte sedimentation rate (ESR) in feline medicine is currently unavailable, while in canine medicine it has been rediscovered due to the introduction of an automated ESR device. …”
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Experiences of and response to the COVID-19 pandemic at private retail pharmacies in Kenya: a mixed-methods study by Edwine Barasa, Sassy Molyneux, Jacinta Nzinga, Audrey Mumbi, Peter Mwangi Mugo, Daniella Munene, Collins Jaguga, Davy Odhiambo, Elizabeth Ominde-Ogaja, Mercy Maina, Michael Mungoma, Nadia Butt, Sultani Matendechero, Titus Kahiga, Eric Sedah, Sylvia Opanga

“…Subsequently, 65 (60%) of 108 pharmacies experienced a dip in demand to below prepandemic levels and 34 (31%) reported challenges with unavailability, high price and poor quality of products. …”
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Minimum elements for reporting a feasibility assessment of algorithms based on routinely collected health data for multi-jurisdiction use: Health Data Research Network Canada recom... by Naomi Hamm, Sharon Bartholomew, Yinshan Zhao, Sandra Peterson, Saeed Al-Azazi, Kimberlyn McGrail, Lisa Lix

“…Whenever algorithm validation studies are not possible due to the unavailability of a reference standard, algorithm feasibility studies can be used to create and assess algorithms for use in more than one population or jurisdiction. …”
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On-Site Evaluation and Improvement Strategies of Radiation Occupational Hazard Prevention and Control Effectiveness in Medical Institution Construction Projects by Xie HX, Zhang MQ, Li ZX, Zhao HL

“…New DR performance testing standards introduced specialized testing items, such as dark noise, detector dose indication (DDI), and signal transmission characteristics (STP), which presented initial challenges due to the unavailability of pre-processing images in some manufacturers’ products. …”
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Relationship between body volume and rib eye area in Colombian buffalo cattle by Sebastián Pineda-Sierra, Divier Antonio Agudelo-Gómez, Edison Julián Ramírez-Toro, Diana Carolina Solano-Suárez, Andrés Felipe Pérez-Rojo

“…A regression model can be used to estimate REA and assist in the selection process of buffaloes for future breeding when real-time ultrasound is unavailable. …”
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Characterization and quantification of solid waste in rural regions by S. Syafrudin, J.M. Masjhoer, M. Maryono

“…However, due to the unavailability of waste generation data, this study aims to measure and analyze waste characteristics in the southern zone of Gunungkidul Regency.METHODS: Primary data collection was taken from 16 randomly selected villages in six sub-districts in Gunungkidul Regency. …”
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Compliance of healthcare workers with the infection prevention and control guidance in tertiary care hospitals: quantitative findings from an explanatory sequential mixed-methods s... by Syed Shariful Islam, Syed Moniruzzaman, M Atiqul Haque, Sarmin Sultana, Marium Salwa, Mohammad Tanvir Islam, Md Maruf Haque Khan

“…Such interventions should also focus on perceived barriers, including unreliability of the information sources, unsafe working places and unavailability of protective equipment and cues to action, including trust in the administration and availability of adequate IPC guidance.…”
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Antimicrobial use in animal farms in Egypt: rates, patterns, and determinants by Nada ElSayed, Amira Amine, Laila El-Attar, Mohamed E. K. Amin

“…An online search was conducted to identify additional farms not included in the list or when the contact information was unavailable. The instrument covered key items related to AMU including types of antimicrobials used, indications, their perceived benefits, and the feed conversion ratio (FCR). …”
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Why and how should we simulate platform trials? Learnings from EU-PEARL by Elias Laurin Meyer, Tobias Mielke, Marta Bofill Roig, Michaela Maria Freitag, Peter Jacko, Pavla Krotka, Peter Mesenbrink, Tom Parke, Sonja Zehetmayer, Dario Zocholl, Franz König

“…We addressed the functionality limitations of existing software as well as the unavailability of the coding therein by developing a suite of open-source software to use in simulating platform trials based on the R programming language. …”
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Clinical Utility of Combined Tissue and Plasma Next-Generation Sequencing in Patients With Advanced, Treatment-Naïve NSCLC by Helena Bote-de Cabo, MD, Marco Siringo, MD, Esther Conde, MD, PhD, Susana Hernández, PhD, Fernando López-Ríos, MD, PhD, Alicia Castelo-Loureiro, MD, Esther García-Lorenzo, MD, Javier Baena, MD-PhD, Mercedes Herrera, MD, Ana Belén Enguita, MD, Yolanda Ruano, PhD, Jon Zugazagoitia, MD, PhD, Luis Paz-Ares, MD, PhD

“…In contrast, adding orthogonal biopsy incremented the detection of ESCAT I or II targetable drivers not only in cases with uninformative testing (undetectable circulating tumor DNA, unavailable/inadequate tissue) but also in about 5% of the patients with seemingly informative but driver undetected molecular results. …”
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Maternal Hepatitis B Infection Burden, Comorbidity and Pregnancy Outcome in a Low-Income Population on the Myanmar-Thailand Border: A Retrospective Cohort Study by Marieke Bierhoff, Chaisiri Angkurawaranon, Aung Myat Min, Mary Ellen Gilder, Nay Win Tun, Arunrot Keereevijitt, Aye Kyi Win, Elsi Win, Verena Ilona Carrara, Tobias Brummaier, Cindy S. Chu, Laurence Thielemans, Kanlaya Sriprawat, Borimas Hanboonkunupakarn, Marcus Rijken, François Nosten, Michele van Vugt, Rose McGready

“…The inclusion criteria were not met for 4,089/15,046 (27.2%) women due mainly to unavailability of pregnancy outcome and nonconfirmation of HBsAg+. …”
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Alteration of Differentiation Potentials by Modulating GATA Transcription Factors in Murine Embryonic Stem Cells by Callinice D. Capo-chichi, Jennifer L. Smedberg, Malgorzata Rula, Emmanuelle Nicolas, Anthony T. Yeung, Richard F. Adamo, Andrey Frolov, Andrew K. Godwin, Xiang-Xi Xu

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Quality of routine malaria data captured at primary health facilities in the Hohoe Municipality, Ghana by Christopher Ayisah, Thywill Worlase Kpenu, Edem Kojo Dzantor, Clement Tetteh Narh

“…Most facilities faced significant issues like unavailability of data, uncompleted data and underreporting of data, making it not-advisable to rely on DHIMS II for critical health decisions. …”
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The clinical application and anatomical analysis of proximal peroneal artery perforator in free fibula flap based on CTA by Yitong Zhao, Danwei Xiang, Lina Song, Zhujiajun Cui, Xingwu Zheng, Tianyu Zhang, Huihui Yang, Yongzhen Fu, Qilin Liu

“…A secondary objective is to confirm their viability when distal perforators are unavailable or when dual-skin paddles are needed. Methods A comprehensive review was conducted involving 50 patients who underwent CTA examinations. …”
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Body mass index, proteinuria and total lymphocyte counts in predicting treatment responses among ART naïve individuals with HIV initiated on antiretroviral treatment in Dar es Sala... by Ellen Hertzmark, Patricia Munseri, Lazaro Jassely, Basil Tumaini

“…In modified Poisson regression, the independent predictors other than CD4 cell counts for viral non-suppression at 6 months among individuals with HIV initiating on ART were BMI loss >5% from baseline to 6 months (adjusted RR 2.73, 95% CI (1.36 to 5.47)), lymphopaenia at 6 months (adjusted RR=4.54, 95% CI (2.19 to 9.39)) and proteinuria at 6 months (adjusted RR=2.63, 95% CI (1.25 to 5.54)).Conclusions Change in BMI, total lymphocyte count and presence of proteinuria can monitor and predict ART response and may be particularly helpful in settings when CD4 counts and viral load monitoring are unavailable.…”
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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Due to the ongoing COVID-19 pandemic, ADAMTS13 testing and complement inhibitor therapy were unavailable. A diagnosis of pregnancy-associated aHUS was made based on the patient's history, clinical presentation, and standard laboratory results. …”
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Magnitude of urban malaria and its associated risk factors in Damboya town, Kambata zone, Central Ethiopia by Biruk Mulachew, Temesgen Bezuayehu, Solomon Asnake

“…Presence of stagnant water (AOR = 3.630, 95 % CI: 1–13, P < 0.049), unavailability of Insecticide-treated bed net (AOR = 3.89, 95 % CI: 1.08–14.01, P < 0.038), living in a house with eaves (AOR = 5.06, 95 %CI: 1.25–20.58, p < 0.023), travel history (AOR = 3.58, 95 %CI: 1–12.79, p < 0.049), low-income (AOR = 5.3, 95 %CI: 1.09–25.2, P < 0.038), were significantly associated with malaria occurrence. …”
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Self-reported knowledge and difficulties towards palliative care among healthcare professionals in rural China: a cross-sectional study by Junwei Niu, Min Feng, Changhui Song, Hui Xie

“…This study aimed to examine the difficulties in providing PC and their factors from the perspective of healthcare professionals in rural Henan province, China, where specific PC services are currently unavailable. Methods A cross-sectional study was conducted between June and July 2024, using a convenience sample of 255 healthcare professionals from four secondary/tertiary hospitals participated. …”
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