Deregulated methylation and expression of PCDHGB7 in patients with non-small cell lung cancer: a novel prognostic and immunological biomarker by Yue Yuan, Yue Yuan, Xin Nie, Jiayi Gao, Jiayi Gao, Yumeng Tian, Yumeng Tian, Liuer He, Liuer He, Xue Wang, Ping Zhang, Junling Ma, Lin Li, Lin Li

“…Its function in lung cancer has not been elucidated.MethodsWe comprehensively investigated PCDHGB7 expression, prognosis, biological function, methylation patterns, and it’s relationship with immune infiltration and immunotherapy response through public datasets (HPA, TCGA, GEO, OncoDB and MEXPRESS). Two lung cancer immunotherapy cohorts from our clinical center were enrolled to detect the relationship between methylation and protein levels of PCDHGB7 in plasma and immunotherapy outcomes.ResultsPCDHGB7 expression was downregulated in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) and associated with tumor prognosis. …”
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Implementasi Metode Naive Bayes untuk Mendeteksi Stres Siswa Berdasarkan Tweet pada Sistem Monitoring Stres by Diva Fardiana Risa, Fajar Pradana, Fitra Abdurrachman Bachtiar

“…Abstract Mental disorders are currently still a problem for the health sector around the world. Stress is one type of mental disorder that can be predicted today. …”
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Comprehensive analysis reveals cholesterol metabolism-related signature for predicting prognosis and guiding individualized treatment of glioma by Dengfeng Lu, Fei Wang, Yayi Yang, Aojie Duan, Yubo Ren, Yun Feng, Haiying Teng, Zhouqing Chen, Xiaoou Sun, Zhong Wang

“…Methods: Transcriptional data and clinicopathological data were obtained from The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) databases. …”
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The Improvement of Protein Retention through a Higher Utilization of Carbohydrate in the Diet with Chromium for Common Carp Cyprinus carpio Linn. by I. Mokoginta, F. Hapsyari, M. Agus Suprayudi

“…Ikan mas berbobot 5,31 ± 0,02 gram per ekor dipelihara dalam akuarium (50x40x35 cm) dengan kepadatan 20 ekor. Ikan diberi pakan tiga kali sehari secara at satiation. Pemberian pakan dilakukan selama 50 hari. …”
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Exploring the Mechanism of Canmei Formula in Preventing and Treating Recurrence of Colorectal Adenoma Based on Data Mining and Algorithm Prediction by Xiaoling Fu, Yimin Xu, Xinyue Han, Xiangying Lin, Jingnan Wang, Guanhong Li, Xiaochen Fu, Min Zhang

“…Using the wSDTNBI algorithm, 1044 prediction targets were predicted, and 3308 differentially expressed genes of CRA were extracted from the TCGA database. Network topology analysis and bioinformatics analysis were performed on 164 intersecting core targets. …”
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Penggunaan Tetes Telinga Serum Autologous dengan Amnion untuk Penutupan Perforasi Membran Timpani by Hidayatul Fitria, Yan Edward

“…Kesimpulan: Diperlukan tiga elemen pada penutupan perforasi membran timpani yaitu faktor regulasi, jembatan (bridge) dan membuat luka baru pada tepi perforasi. …”
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Pollution index and load of total nitrogen and phosphate on agriculture and fisheries in Jatigede Reservoir by Zulfia Kamila Mutia, Denny Kurniadie, Dadan Sumiarsa

“…Hasil dari index pencemaran paling tinggi terdapat di stasiun tiga sebesar 6,08 dengan status tercemar sedang disebabkan oleh limpasan dari limbah inlet cihonje dan aktivitas KJA dan untuk beban pencemaran parameter nitrogen memiliki jumlah yang tinggi yaitu 192,13 kg/hari kemudian jumlah beban pencemaran fosfat 34,16 kg/hari. …”
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Cloning and sequencing of VP19-encoding gene of white spot syndrome virus from Situbondo’s isolate by Sahrul Alim, Dinamella Wahjuningrum, Muhamad Ali

“…Namun hasil pengurutan menunjukkan adanya perbedaan lima basa dan tiga asam amino penyusun sekuen VP19 isolat Situbondo dengan isolat dari beberapa negara lain. …”
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Combining single-cell analysis and molecular docking techniques to construct a prognostic model for colon adenocarcinoma and uncovering inhibin subunit βb as a novel therapeutic ta... by Qinqing Wu, Qinqing Wu, Lu Ye, Yuwei Wu, Mengyu Zhao, Mengyu Zhao, Jiaxin Lu, Yanping Yu, Yanping Yu, Yixiao Niu, Yixiao Niu, Luxiao Zhang, Peijun Zuo, Peijun Zuo

“…BackgroundColon adenocarcinoma (COAD) is a malignancy with a high mortality rate and complex biological characteristics and heterogeneity, which poses challenges for clinical treatment. Anoikis is a type of programmed cell death that occurs when cells lose their attachment to the extracellular matrix (ECM), and it plays a crucial role in tumor metastasis. …”
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Assessment of prognosis and responsiveness to immunotherapy in colorectal cancer patients based on the level of immune cell infiltration by Kaili Liao, Minqi Zhu, Lei Guo, Zijun Gao, Jinting Cheng, Bing Sun, Yihui Qian, Bingying Lin, Jingyan Zhang, Tingyi Qian, Yixin Jiang, Yanmei Xu, Qionghui Zhong, Xiaozhong Wang

“…ObjectiveTo build a new prognostic risk assessment model based on immune cell co-expression networks for predicting overall survival and evaluating the efficacy of immunotherapy for colon cancer patients.MethodsThe Cancer Genome Atlas (TCGA) database was used to obtain mRNA expression profiling data, clinical information, and somatic mutation data from colorectal cancer patients. …”
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Control of marine leeches infecting hybrid grouper Epinephelus fuscoguttatus >< E. lanceolatus with garlic Allium sativum powder by Aminatul Zahra, Dwi Septiani Putri

“…Penelitian ini menggunakan rancangan acak faktorial (faktor konsentrasi dan faktor lama perendaman bawang putih) dengan sembilan perlakuan dan tiga ulangan. Perlakuan di dalam penelitian ini adalah kombinasi antara konsentrasi tepung bawang putih 0%, 3%, 6%, dan lama perendaman 20 menit, 40 menit, dan 60 menit. …”
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Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target by Chao Xu, Litao Liang, Guoqing Liu, Yanzhi Feng, Bin Xu, Deming Zhu, Wenbo Jia, Jinyi Wang, Wenhu Zhao, Xiangyu Ling, Yongping Zhou, Wenzhou Ding, Lianbao Kong

“…We utilized data from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO), applying machine learning algorithms to develop a prognostic model based on ACRRGs’ expression. …”
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Fish oil supplementation in commercial diet on growth of Anguilla bicolor bicolor by Retno Cahya Mukti, Nur Bambang Priyo Utomo, Ridwan Affandi

“…Semua perlakuan terdiri atas tiga ulangan. Pakan diberikan sebanyak 3% dari biomassa ikan dan diberikan sebanyak empat kali sehari yaitu pukul 06.00, 11.00, 16.00 dan 21.00. …”
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Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer by Yuqi Wang, Yunlong Zhang, Min Liu, Yu Liu, Yu Zeng, Wei Zhang, Shuping Wu, Linfei Hu, Xianhui Ruan, Xiangqian Zheng, Ming Gao, Jingzhu Zhao

“…This study aimed to explore the relationship between PCD-related genes expression and prognosis in thyroid cancer (THCA), especially IL20RA, as a potential prognostic marker for THCA. …”
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Integration analysis of microRNAs as potential biomarkers in early-stage lung adenocarcinoma: the diagnostic and therapeutic significance of miR-183-3p by Guodong Huang, Yuxia Liu, Lisha Li, Bing Li, Ting Jiang, Yufeng Cao, Xiaoping Yang, Xinning Liu, Honglin Qu, Shitao Li, Xin Zheng

“…Additionally, we evaluated the clinical significance of miRNAs by the TCGA database. miR-183-3p was chosen for subsequent biological functional studies by cell proliferation assays, cell migration and cell invasion assays, cell apoptosis and cell cycle assays in LUAD cells. …”
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An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis by Xiaolu Yang, Xiaolu Yang, Yilun Li, Yilun Li, Yaqi Peng, Yuan Chang, Binglu He, Binglu He, Tianqi Zhang, Tianqi Zhang, Shiyu Zhang, Cuizhi Geng, Yunjiang Liu, Xiaolong Li, Jun Hao, Li Ma

“…This study aims to elucidate the function of ASCL1 in BC using bioinformatics analyses, as well as in vitro and in vivo experimental approaches.MethodsData from the TCGA, GEO, and Human Protein Atlas databases were utilized to evaluate ASCL1 expression in BC and its association with patient prognosis. …”
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Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer by Tiankai Xu, Chu Chu, Shuyu Xue, Tongchao Jiang, Ying Wang, Wen Xia, Huanxin Lin

“…By merging these genes with differentially expressed genes observed in normal and tumor tissues from the TCGA-BRCA and GEO databases, we successfully identified the DMRDEGs. …”
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Ovulation time and ovulated eggs count of sneakehead Channa striata induced by prostaglandin 2α with different doses by Frits Jamlaay, Maheno Sri Widodo, Abd. Rahem Faqih

“…Setiap perlakuan terdiri atas tiga ekor induk sebagai ulangan. Waktu ovulasi diamati sampai dengan 72 jam pascasuntik. …”
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SEED (Stoke Disease Early Detection Application) - Rancang Bangun Aplikasi Mobile Berbasis Android untuk Mendiagnosis Gejala Dini Penyakit Stroke Menggunakan K-Nearest Neighbor (K-... by Dedin Anike Putra, Muhammad Dimas Setiawan Sanapiah, Azifatul Istna Hanifah, Tri Afirianto

“…Pada zaman modern, stroke tidak hanya menyerang orang yang sudah lanjut usia namun juga bisa menyerang orang usia muda. Data dari Rumah Sakit Saiful Anwar (RSSA) Kota Malang, sepanjang tahun 2016 penderita penyakit stroke 30% nya masih diusia muda, yaitu antara usia 18 – 40 tahun. …”
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Kemampuan Daya Hambat Bahan Aktif Beberapa Merek Dagang Hand sanitizer terhadap Pertumbuhan Staphylococcus aureus by Putri Srikartika, Netti Suharti, Eliza Anas

“…Penelitian dilakukan dengan metode rancangan acak lengkap pada empat macam <em>hand sanitizer</em> dengan tiga kali pengulangan. Data diolah secara manual dan menggunakan analisis varians (ANOVA) dilanjutkan dengan uji <em>pos-hoc</em> dengan Tukey HSD dan <em>i</em><em>ndependent t</em><em> test</em>. …”
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