The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus by Aslıhan Şeyda DOĞAN, Mukaddes PALA, Şenay GÖRÜCÜ YILMAZ, Ayfer BECEREN, Aydın KARABULUT, Yalçın POLAT, Hatice Kübra ELÇİOĞLU

“…Methods: Therefore, miRNAs obtained from rat heart tissue were analyzed by microarray, and twelve miRNAs (rno-miR-200c-3p, rno-miR-129-5p, rno-miR-150-3p, rno-miR-3584-5p, rno-miR-34c-3p, rno-miR-342-3p, rno-miR-466b-3p, rno-miR-466c-3p, rno-miR-31a-3p, rno-miR-15b-5p, rno-miR-196b-3p, and rno-miR-208a-5p) with changed expression levels were validated by real-time polymerase chain reaction analysis. …”
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Telomerase inhibiting phytochemicals derived from Blumea eriantha for cancer treatment: A comprehensive computational analysis by Rahil Ummar Faruk Abbu, Shaik Mohammad Abdul Fayaz, Divyashree M S, Raghu Chandrashekhar H, Prasanna Kumar Reddy Gayam, Archana Mahadev Rao

“…This study investigates the anti-telomerase activity of twelve phytochemicals derived from Blumea eriantha for cancer treatment. …”
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Noninvasive Brain Stimulations for Unilateral Spatial Neglect after Stroke: A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Controlled Trials by Flávio Taira Kashiwagi, Regina El Dib, Huda Gomaa, Nermeen Gawish, Erica Aranha Suzumura, Taís Regina da Silva, Fernanda Cristina Winckler, Juli Thomaz de Souza, Adriana Bastos Conforto, Gustavo José Luvizutto, Rodrigo Bazan

“…Studies were selected if they were controlled and noncontrolled trials examining transcranial direct current stimulation (tDCS), repetitive transcranial magnetic stimulation (rTMS), and theta burst stimulation (TBS) in USN after stroke, with outcomes measured by standardized USN and functional tests. Results. Twelve RCTs (273 participants) and 4 non-RCTs (94 participants) proved eligible. …”
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Conflict-associated wounds and burns infected with GLASS pathogens in the Eastern Mediterranean Region: A systematic review by Amelia Wild, Clare Shortall, Omar Dewachi, Carine Naim, Alex Green, Sarah Hussain, Aula Abbara

“…Search terms included “wounds”, “burns,” “antimicrobial resistance”, and the twelve countries of interest. Included studies reported resistance of GLASS pathogens. …”
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Challenges and support factors in managing type 2 diabetes among pregnant women in Thailand: A convergent mixed-methods study by Ratchanok Phonyiam, Chiao-Hsin Teng, Catherine Sullivan, Aunchalee Palmquist, Eric Hodges, Yamnia Cortés, Marianne Baernholdt

“…Side-by-side matrices were used to describe the qualitative subthemes with quantitative results. Results: Twelve Thai pregnant women participated in the study, aged 27 to 40 years, with gestational ages ranging from 7 to 38 weeks and T2DM diagnoses spanning from 3 weeks to 10 years. …”
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WINTER HARDINESS OF BREAD WHEAT FROM THE VIR COLLECTION IN ENVIRONMENTS OF THE NORTHWESTERN AND CENTRAL BLACK SOIL REGIONS OF RUSSIA by N. S. Lysenko, V. F. Loseva, O. P. Mitrofanova

“…By using the cluster analysis (k-means algorithm), the target sub-collec­tion structure has been revealed. Twelve accessions that overwintered well at both geographical locations during all the years of testing were identified.…”
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Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of <i>Centella asiatica</i> by Steven R. Chamberlin, Jonathan A. Zweig, Cody J. Neff, Luke Marney, Jaewoo Choi, Liping Yang, Claudia S. Maier, Amala Soumyanath, Shannon McWeeney, Nora E. Gray

“…<b>Methods:</b> Mouse primary cortical neurons were treated with CAW or equivalent concentrations of four TT combined, eight CQA combined, or these twelve compounds combined (TTCQA). Treatment effects on the cell transcriptome (18,491 genes) and metabolome (192 metabolites) relative to vehicle control were evaluated using RNAseq and metabolomic analyses, respectively. …”
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Systemic Inflammatory Markers for Predicting Overall Survival in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis by Xiaotong Song, Hao Zhang, Fanxing Yin, Panpan Guo, Xiaocheng Yang, Jinzhu Liu, Yanshuo Han, Zhaozhou Ren

“…Hazard ratios (HRs) for overall survival (OS) and disease-specific survival (DPS) were extracted for the investigation of the prognostic value of inflammatory markers. Results. Twelve researches with 2162 osteosarcoma patients were included in total. …”
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From Acceptance to Dependence: Exploring Influences of Smart Healthcare on Continuous Use Intention of Mobile Health Services Among Older Adults with Chronic Illnesses in China by Jiacheng Luo, Kewei Zhang, Qianghong Huang, Shan Jiang, Younghwan Pan

“…In total, only one of the twelve hypotheses was not supported. This study not only provides strong evidence for the effectiveness of the integrated TAM and VAM model in the mHealth field but also offers theoretical insights and practical recommendations for product optimization and promotion to mHealth service providers and designers.…”
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Deciphering Regulatory Networks Governing Seedling Emergence in Deep-Sown Direct-Seeded Rice Cultivation by Jasneet Singh, Nitika Sandhu, Aman Kumar, Om Prakash Raigar, Sutej Bains, Gaurav Augustine, Muskan Gupta, Ekta Kharche, Anu Kalia, Navtej Singh Bains, Arvind Kumar

“…On average, a total of 2702 differentially expressed genes were identified across twelve inter- and intra-genotypic pairwise differential expression analyses, with a false discovery rate ≤ 0.05 and log2 fold change ≥ ± 2. …”
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Investigation into the influence of mild hypothermia on regulating ferroptosis through the P53-SLC7A11/GPX4 signaling pathway in sepsis-induced acute lung injury by Liujun Tao, Jie Xu, Liangyan Jiang, Juntao Hu, Zhanhong Tang

“…Sepsis was induced using the cecum ligation and puncture (CLP) method, after which rats were subjected to either normothermic (36–38 °C) or mild hypothermic (32–34 °C) conditions for a duration of 10 h. Twelve hours post-surgery, blood samples, bronchoalveolar lavage fluid, and lung tissue samples were harvested for histological analysis, measurement of inflammatory markers, wet/dry ratios, blood gas analysis, assessment of oxidative stress and ferroptosis, Western blotting, and RT-qPCR analysis. …”
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Functional Connectivity and MRI Radiomics Biomarkers of Cognitive and Brain Reserve in Post-Stroke Cognitive Impairment Prediction—A Study Protocol by Hanna Maria Dragoș, Adina Stan, Livia Livinț Popa, Roxana Pintican, Diana Feier, Nicu Cătălin Drăghici, Dragoș-Cătălin Jianu, Diana Chira, Ștefan Strilciuc, Dafin F. Mureșanu

“…The primary outcome will be PSCI occurrence, and it will be assessed at six and twelve months after AIS. Secondary outcomes will include PSCI severity, recurrent AIS, and mortality. …”
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Pleural metastases from differentiated thyroid cancer: clinical features and long-term outcomes by Mengyue Liu, Juan Tang, Nan Sun, Chuang Xi, Chentian Shen, Song Hongjun, Quanyong Luo, Xianzhao Deng, Zhongling Qiu

“…At the end of follow-up, eight patients (29.63%) had disease progression (PD), four (14.81%) had a partial response, and the remainder had stable disease; no patient achieved complete response. Twelve patients (44.44%) died, and 15 (55.56%) survived. …”
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Dengue dynamics, predictions, and future increase under changing monsoon climate in India by Yacob Sophia, Mathew Koll Roxy, Raghu Murtugudde, Anand Karipot, Amir Sapkota, Panini Dasgupta, Kalpana Baliwant, Sujata Saunik, Abhiyant Tiwari, Rajib Chattopadhyay, Revati K. Phalkey

“…Dengue mortality and meteorological conditions over a twelve-year period (2004–2015) are analyzed using statistical tools and machine learning methods. …”
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Multiple time points for detecting circulating tumor DNA to monitor the response to neoadjuvant therapy in breast cancer: a meta-analysis by Shuyi Niu, Tie Sun, Mozhi Wang, Litong Yao, Tianyi He, Yusong Wang, Hengjun Zhang, Xiang Li, Yingying Xu

“…Results Thirteen reports from twelve studies were eligible for inclusion in this meta-analysis. …”
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Selective dorsal rhizotomy long-term effects on functional motility in Jordanian children with spastic cerebral palsy by Yazan E. Al-kharabsheh, Anas Said, Ismail A. Ismaiel, Issam Khawaja, Marwan Altaher, Ali Bani-Ahmed, Carmen M. Cirstea, Carmen M. Cirstea

“…These findings suggest that younger children (&lt;10 years old) and more impaired (levels IV and V on GMFCS) are likely the best candidates for this procedure. Twelve-month functional improvement was similar in boys and girls (GMFCS decreased in 44.0% of boys vs. 37.5% of girls). …”
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The effects of age and sex on reference intervals for cobalamin, homocysteine, and serum and urinary methylmalonic acid in healthy adult dogs by Anna‐Lena Proksch, Sophia Schaefer, Vanessa Dreller, Judith Langenstein, Ralph Fingerhut, Natali Bauer, Andreas Moritz

“…In dogs with outlying data, changes in health, markersB12met, and onset of gastrointestinal signs were reevaluated after 9‐15 months. Results Twelve of 120 healthy dogs had abnormal uMMA:crea ratios. …”
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Macro- and Micro-Nutrient Composition and Antioxidant Activity of Chickpea and Pea Accessions by Michela Costantini, Carmine Summo, Mariangela Centrone, Iga Rybicka, Mariagrazia D’Agostino, Paolo Annicchiarico, Francesco Caponio, Stefano Pavan, Grazia Tamma, Antonella Pasqualone

“…In this paper, five pea ( Pisum sativum L.) and twelve chickpea ( Cicer arietinum L.) accessions, having different characteristics and geographical origin, were characterised in terms of antioxidant activity, as well as macro- and micro-nutrient composition. …”
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Rapid identification of high-temperature Daqu Baijiu with the same aroma type by UV-VIS sensor of HBT combined with Zn2+ by Yanmei Zhu, Yuanyuan Su, Yipeng Cang, Hengye Chen, Wanjun Long, Wei Lan, Xue Jiang, Haiyan Fu

“…The accuracy of the data driven-soft independent modelling of class analogies (DD-SIMCA) model was between 90% and 100%, indicating that the array sensor had a good recognition effect on the adulteration of the same aroma type of Baijiu. Twelve kinds of Maillard reaction products such as tetramethylpyrazine, 2,6-dimethylpyrazine, and furfural in Baijiu were predicted successfully, and the deviation between the real value and the predicted value was less than 1.8746% ± 1.4515%. …”
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Efficacy of i-Scan Imaging for the Detection and Diagnosis of Early Gastric Carcinomas by Junichi Nishimura, Jun Nishikawa, Munetaka Nakamura, Atsushi Goto, Kouichi Hamabe, Shinichi Hashimoto, Takeshi Okamoto, Masato Suenaga, Yusuke Fujita, Yoshihiko Hamamoto, Isao Sakaida

“…White light and i-Scan moving images recorded from these patients in twin mode were separated into white light and i-Scan. Twelve endoscopists (three different skill levels) blinded to patient information evaluated the images. …”
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