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  1. 1921
  2. 1922

    Exploring Potential Causal Links: How Parkinson’s Disease Brain Damage Impacts Liver Health–A Mendelian Randomization and Transcriptomic Study by Liu T, Chen Q, Wu H, Li J, Xian M, Lu K, Zhu C, Wei J

    Published 2025-06-01
    “…Furthermore, the impact of PD treatment drugs on liver function was also evaluated. These findings provide important insights for the development of future PD treatment strategies, and further clinical research is needed to validate and optimize clinical interventions to maximize treatment efficacy and minimize side effects in patients with PD.Keywords: Parkinson’s disease, chronic hepatitis, Mendelian randomization analysis, serum metabolites, cysteine…”
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    Article
  3. 1923

    Comprehensive transcriptomic analysis integrating bulk and single-cell RNA-seq with machine learning to identify and validate mitochondrial unfolded protein response biomarkers in... by Lu Zhang, Lei Yue, Peng Jia, Peng Jia, Ziqi Cheng, Jiwen Liu

    Published 2025-04-01
    “…Additionally, in the single-cell transcriptome data, these biomarkers were predominantly enriched in neutrophils. …”
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    Article
  4. 1924
  5. 1925
  6. 1926

    Whole-transcriptome analysis reveals the characteristics of intramuscular fat circRNA expression and its associated network in grazing yaks of different months of age under cold st... by Yaqian Liu, Yonggang Sun, Yincang Han, Weiqin Ding, Shengwei Jin, Jianyu Chen, Fajie Gou

    Published 2025-03-01
    “…Whole-transcriptome analysis reveals the characteristics of intramuscular fat circRNA expression and its associated network in grazing yaks of different months of age under cold stress. …”
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    Article
  7. 1927

    Integration of histopathology, transcriptomics and non-targeted metabolomics reveals toxic effects of thiamethoxam under acute stress in mirror carp (Cyprinus carpio var. Longke-11... by Dongchang Guo, Wenyang Song, Manhong Liu, Haixia Jiang, Xiaolong Wang, Zhiying Jia, Bin Xu

    Published 2025-05-01
    “…In this study, using histopathology, transcriptomics, and non-targeted metabolomics, the toxic effects of different concentrations of THM under acute stress (96 h) were investigated in mirror carp (Cyprinus carpio var. …”
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    Article
  8. 1928

    Transcriptome Profiling of Spike Development Reveals Key Genes and Pathways Associated with Early Heading in Wheat–<i>Psathyrstachys huashanica</i> 7Ns Chromosome Addition Line by Binwen Tan, Yangqiu Xie, Hang Peng, Miaomiao Wang, Wei Zhu, Lili Xu, Yiran Cheng, Yi Wang, Jian Zeng, Xing Fan, Lina Sha, Haiqin Zhang, Peng Qin, Yonghong Zhou, Dandan Wu, Yinghui Li, Houyang Kang

    Published 2025-07-01
    “…To explore the potential molecular mechanisms underlying the early heading, we performed transcriptome analysis at four different developmental stages of the 7Ns disomic addition line and its wheat parents. …”
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    Article
  9. 1929
  10. 1930

    CXCL14 drives age-related intervertebral disc degeneration via NF-κB pathway activation in a multiomic study by Tianle Zhou, Tonghui Zhang, Qiwang He, Zhiwen Zhang, Yong Huang, Zijun Chen, Wei Wang

    Published 2025-07-01
    “…We used transcriptomic and proteomic analyses to identify key regulatory genes associated with IDD. …”
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    Article
  11. 1931

    Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats by Gao Gong, Shijie Bi, Xin Liang, Yu Ao, Feng Xu, Yiming Sulaiman

    Published 2025-05-01
    “…These genes play an important role in the development of secondary hair follicles and the formation of cashmere quality in cashmere goats, providing a theoretical basis for the genetic improvement of cashmere goats in the future.…”
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    Article
  12. 1932

    Actively expressed microbiota in mucosal biopsies of treatment-naïve ulcerative colitis patients by Line Strand Karlsholm, Rafi Ahmad, Hagar Taman, Christopher G. Fenton, Ruth H. Paulssen

    Published 2025-12-01
    “…Transcriptomic sequences that mapped to the human genome were removed from the dataset. …”
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    Article
  13. 1933

    Dataset from RNAseq analysis of differential gene expression in germinal vesicle and metaphase I stages of granulosa cellsNational Center for Biotechnology Information by Weijun Gong, Xiangqian Meng, Ping Lei, Penghao Li, Jing Li, Yan Zhu

    Published 2025-04-01
    “…We further evaluated the transcriptomic data via genomes from gene banks. Thus, these new data demonstrate the feasibility of obtaining reliable transcriptomic data from individual samples at different developmental stages, and provide a framework for systematic transcriptomic studies of granulosa cell development.…”
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    Article
  14. 1934

    Multiomics analyses of the effects of LED white light on the ripening of apricot fruits by Chunmei Bai, Yanyan Zheng, Christopher Brian Watkins, Lili Ma, Yuanye Jiang, Shaoqing Chen, Hongwei Wang, Xuelian He, Lichun Han, Xinyuan Zhou, Qing Wang, Caie Wu, Jinhua Zuo

    Published 2025-01-01
    “…These data were combined with transcriptomic, metabolomic, and ATAC-Seq data from fruits taken on 8 d of treatment to provide insight into the potential mechanism by which LED treatment delays ripening. …”
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    Article
  15. 1935

    Function analysis of LIPI-4 in Listeria monocytogenes reveals a key role of flagella formation in the regulation of virulence by Caixia Liu, Xun Ma, Bin Jia, Ruixuan Qian, Shengjie Gao, Lu Liu, Yatao Qi, Zhongke Yin, Guangdong Hu, Jing Wang

    Published 2025-12-01
    “…Our research demonstrates that LIPI-4 promotes flagellum formation through metabolic regulation, thereby enhancing L. monocytogenes colonization and cellular invasion. This discovery provides novel insights into the pathogenic mechanisms of L. monocytogenes.…”
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    Article
  16. 1936

    Improvement of D-lactic acid production from methanol by metabolically engineered Komagataella phaffii via ultra-violet mutagenesis by Yoshifumi Inoue, Kaito Nakamura, Ryosuke Yamada, Takuya Matsumoto, Hiroyasu Ogino

    Published 2025-06-01
    “…The resulting mutant strain DLac_Mut2_221 produced 5.38 g/L of D-lactic acid from methanol, a 1.52-fold increase compared to the parent strain GS115/S8/Z3. The transcriptome analysis of the mutant DLac_Mut2_221 identified 158 differentially expressed genes, providing insights into key mechanisms contributing to enhanced D-lactic acid production. …”
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    Article
  17. 1937

    Degradation of lignocellulose by different bacterial and fungal co-cultures by Julian Detain, Ludovic Besaury

    Published 2024-01-01
    “…This work provided the proof of concept for technological feasibility, pertinence and usefulness of interdomain co-culture.…”
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    Article
  18. 1938
  19. 1939
  20. 1940

    Foliar calcium application reduces fluorine accumulation in tea plant by regulating cell wall structure and gene expression by Jinlei Luo, Jinlei Luo, Lintao Zhang, Daili Li, Shuangjie Huang, Chunlei Li, Yi Chen, Yi Chen, Peng Yin, Wei Liu, Mufang Sun, Mufang Sun, Guiyi Guo, Guiyi Guo, Guiyi Guo

    Published 2025-01-01
    “…All the results suggest that Ca may lessen the tea leaf F level by reducing the accumulation of cell wall materials and intervening the cell wall structure and gene expression. This study provided useful information for reducing the F level and solving the F safety problem in tea plant.…”
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    Article