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1921
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1922
Exploring Potential Causal Links: How Parkinson’s Disease Brain Damage Impacts Liver Health–A Mendelian Randomization and Transcriptomic Study
Published 2025-06-01“…Furthermore, the impact of PD treatment drugs on liver function was also evaluated. These findings provide important insights for the development of future PD treatment strategies, and further clinical research is needed to validate and optimize clinical interventions to maximize treatment efficacy and minimize side effects in patients with PD.Keywords: Parkinson’s disease, chronic hepatitis, Mendelian randomization analysis, serum metabolites, cysteine…”
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1923
Comprehensive transcriptomic analysis integrating bulk and single-cell RNA-seq with machine learning to identify and validate mitochondrial unfolded protein response biomarkers in...
Published 2025-04-01“…Additionally, in the single-cell transcriptome data, these biomarkers were predominantly enriched in neutrophils. …”
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1924
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1925
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1926
Whole-transcriptome analysis reveals the characteristics of intramuscular fat circRNA expression and its associated network in grazing yaks of different months of age under cold st...
Published 2025-03-01“…Whole-transcriptome analysis reveals the characteristics of intramuscular fat circRNA expression and its associated network in grazing yaks of different months of age under cold stress. …”
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1927
Integration of histopathology, transcriptomics and non-targeted metabolomics reveals toxic effects of thiamethoxam under acute stress in mirror carp (Cyprinus carpio var. Longke-11...
Published 2025-05-01“…In this study, using histopathology, transcriptomics, and non-targeted metabolomics, the toxic effects of different concentrations of THM under acute stress (96 h) were investigated in mirror carp (Cyprinus carpio var. …”
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1928
Transcriptome Profiling of Spike Development Reveals Key Genes and Pathways Associated with Early Heading in Wheat–<i>Psathyrstachys huashanica</i> 7Ns Chromosome Addition Line
Published 2025-07-01“…To explore the potential molecular mechanisms underlying the early heading, we performed transcriptome analysis at four different developmental stages of the 7Ns disomic addition line and its wheat parents. …”
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1929
Permanent crop cover as a strategy for drought-resistant viticulture: insights on how rhizosphere metagenomics influences leaf-level -omics for an enhanced overall plant response
Published 2025-05-01“…Our study is the first to show that cover cropping can boost cash crop resilience to drought through intricate plant–soil–microbe interactions, providing benefits from the outset.…”
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1930
CXCL14 drives age-related intervertebral disc degeneration via NF-κB pathway activation in a multiomic study
Published 2025-07-01“…We used transcriptomic and proteomic analyses to identify key regulatory genes associated with IDD. …”
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1931
Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats
Published 2025-05-01“…These genes play an important role in the development of secondary hair follicles and the formation of cashmere quality in cashmere goats, providing a theoretical basis for the genetic improvement of cashmere goats in the future.…”
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1932
Actively expressed microbiota in mucosal biopsies of treatment-naïve ulcerative colitis patients
Published 2025-12-01“…Transcriptomic sequences that mapped to the human genome were removed from the dataset. …”
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1933
Dataset from RNAseq analysis of differential gene expression in germinal vesicle and metaphase I stages of granulosa cellsNational Center for Biotechnology Information
Published 2025-04-01“…We further evaluated the transcriptomic data via genomes from gene banks. Thus, these new data demonstrate the feasibility of obtaining reliable transcriptomic data from individual samples at different developmental stages, and provide a framework for systematic transcriptomic studies of granulosa cell development.…”
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1934
Multiomics analyses of the effects of LED white light on the ripening of apricot fruits
Published 2025-01-01“…These data were combined with transcriptomic, metabolomic, and ATAC-Seq data from fruits taken on 8 d of treatment to provide insight into the potential mechanism by which LED treatment delays ripening. …”
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1935
Function analysis of LIPI-4 in Listeria monocytogenes reveals a key role of flagella formation in the regulation of virulence
Published 2025-12-01“…Our research demonstrates that LIPI-4 promotes flagellum formation through metabolic regulation, thereby enhancing L. monocytogenes colonization and cellular invasion. This discovery provides novel insights into the pathogenic mechanisms of L. monocytogenes.…”
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1936
Improvement of D-lactic acid production from methanol by metabolically engineered Komagataella phaffii via ultra-violet mutagenesis
Published 2025-06-01“…The resulting mutant strain DLac_Mut2_221 produced 5.38 g/L of D-lactic acid from methanol, a 1.52-fold increase compared to the parent strain GS115/S8/Z3. The transcriptome analysis of the mutant DLac_Mut2_221 identified 158 differentially expressed genes, providing insights into key mechanisms contributing to enhanced D-lactic acid production. …”
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1937
Degradation of lignocellulose by different bacterial and fungal co-cultures
Published 2024-01-01“…This work provided the proof of concept for technological feasibility, pertinence and usefulness of interdomain co-culture.…”
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1938
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1939
Metabolic mapping of the human solute carrier superfamily
Published 2025-05-01“…Targeted metabolomics provided a fingerprint of 189 intracellular metabolites, while transcriptomics offered insights into cellular programs modulated by SLC expression. …”
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1940
Foliar calcium application reduces fluorine accumulation in tea plant by regulating cell wall structure and gene expression
Published 2025-01-01“…All the results suggest that Ca may lessen the tea leaf F level by reducing the accumulation of cell wall materials and intervening the cell wall structure and gene expression. This study provided useful information for reducing the F level and solving the F safety problem in tea plant.…”
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