RNA-Seq Analysis Revealed the Virulence Regulatory Network Mediated by the Ferric Uptake Regulator (Fur) in <i>Apostichopus japonicus</i> Pathogenesis Induced by <i>Vibrio splendid... by Changyu Liao, Lincheng Hu, Si Zhu, Weikang Liang, Lei Yang, Chenghua Li

“…Consistent with the transcriptomic results, <i>Vsfur</i> knockdown resulted in reduced antioxidant capacity, bacterial competitiveness, and cytotoxicity in <i>V. splendidus</i>. …”
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Understanding the transition from embryogenesis to seed filling in Phaseolus vulgaris L. non-endospermic seeds by Cláudia Lopes, Pedro Fevereiro, Susana de Sousa Araújo, Susana de Sousa Araújo

“…Transcriptomic analysis further supported this finding, showing upregulation of genes associated with seed storage proteins, starch metabolism, and hormonal regulation at 14 and 18 DAA. …”
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Dynamic identification of candidate genes associated with higher tocopherol biosynthesis in Brassica napus seeds by Yunyun Zhang, Yunyun Zhang, Ping Qin, Yajun Liu, Yingnan Liu, Wenjing Li, Chunjuan Luo, Peng Chen, Chunyu Zhang

“…These results contribute to an advanced understanding of the regulatory mechanisms underlying seed VE biosynthesis in oilseed crops and provide valuable genetic resources for enhancing rapeseed nutritional quality through vitamin E biofortification.…”
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The interplay between RNA m6A modification and radiation biology of cancerous and non-cancerous tissues: a narrative review by Yajia Cheng, Yue Shang, Shuqin Zhang, Saijun Fan

“…This review highlights the importance of m6A modification in the context of radiation biology. Targeting epi-transcriptomic molecules might potentially provide a novel strategy for enhancing the radiosensitivity of cancerous tissues and mitigating radiation-induced injury to normal tissues.…”
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Identification of Crucial Genes Associated With MYCN‐Driven Neuroblastoma Based on Single‐Cell Analysis and Machine Learning by Jiasi Zhang, Yichen Lei, Yaqin Wang, Wen Yu, Xiaoyan Zhao, Yongbing Zhu, Dedong Zhang, Siying Liu, Aiguo Liu

“…Methods We performed single‐cell transcriptomic analysis comparing NB samples with and without MYCN. …”
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Identification of cepharanthine as an effective inhibitor of African swine fever virus replication by Chuanxiang Qi, Jiyoung Lee, Yongqiang Zhang, Huan Chen, Jiaxuan Lv, Zhenzhong Wang, Jinming Li, Xiaodong Wu, Yong-Sam Jung, Zhiliang Wang, Yingjuan Qian

“…To further investigate the mechanism through which CEP inhibits ASFV replication, transcriptome profiles were generated in PAMs treated with CEP and/or infected with ASFV. …”
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Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles by Yukun Song, Erhan Hai, Lixia He, Ning Zhang, Nan Zhang, Junlan Wang, Yupeng Sun, Dengke Zeng, Jiaxin Zhang, Jiaxin Zhang

“…Functional enrichment of atretic follicle fluid highlighted pathways related to linoleic acid and purine metabolism. Transcriptomic analysis revealed 250 highly expressed genes in ovarian granulosa cells of atretic follicles. …”
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Multi-omics revealed the mechanism of feed efficiency in sheep by the combined action of the host and rumen microbiota by Guangchen Zhou, Junda Li, Xuhui Liang, Bohua Yang, Ximeng He, Hongyu Tang, Hongran Guo, Gongwei Liu, Wenyuan Cui, Yulin Chen, Yuxin Yang

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Isolation, phylogenetics, and characterization of a new PDCoV strain that affects cellular gene expression in human cells by Xiaozhu Yang, Hanwei Yin, Mengyuan Liu, Xuemei Wang, Tao Song, Aiai Song, Yibo Xi, Ting Zhang, Zilong Sun, Wei Li, Sheng Niu, Farwa Zainab, Chenyang Wang, Ding Zhang, Haidong Wang, Bo Yang

“…Collectively, our findings provide new insights into the characteristics and mechanisms of PDCoV infection.…”
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Alternative N-forms cause differential response to the soil-borne disease Fusarium oxysporum f. sp. melongenae in eggplant (Solanum melongena L.) by MR Tassone, TM Sirangelo, G Puccio, K Gazzetti, A Mauceri, MR Abenavoli, F Sunseri, GL Rotino, L Toppino, F Mercati

“…This was marked by higher expression levels of genes associated with Reactive Oxygen Species (ROS) and Resistance (R) responses, as well as the upregulation of genes involved in cell wall development, including cellulose biosynthesis (CSLG1, CSLH1) and membrane sterol production (SQE2), suggesting a potential thickening of the cell wall to hinder fungal invasion.Our study provides new valuable insights into the molecular mechanisms induced by Fom infection under alternative N-forms supply, contributing to the identification of improved fertilization strategies for disease management in eggplant, in support of more sustainable and low-impact agriculture.…”
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Enhanced propionate and butyrate metabolism in cecal microbiota contributes to cold-stress adaptation in sheep by Xindong Cheng, Yanping Liang, Kaixi Ji, Mengyu Feng, Xia Du, Dan Jiao, Xiukun Wu, Chongyue Zhong, Haitao Cong, Guo Yang

“…Herein, we simulated a winter environment (− 20 °C) and provided a rationed diet to compare the cold adaptation mechanisms between Hulunbuir and Hu sheep. …”
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Integrative Transcriptomics and Metabolomics Reveal the Key Metabolic Pathways in Endophyte-Infected Rice Seedlings Resistance to Na₂CO₃ Stress by Xinnan Wang, Yanan Li, Hefei Sun, Lihong Zhang, Xuemei Li

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Primordial follicle activation related genes screening and differential expressed analysis by transcriptome sequencing in buffalo ovary after PI3K and mTOR stimulators activated by Jingyuan Liang, Peng Zhu, Qiao Lv, Yu Pan, Ziyan Gao, Qinghua Xing, Ruimen Zhang, Yanfei Deng, Sufang Yang

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Discovering molecular signatures in kidney transplant biopsies with borderline changes and isolated V-lesions: single-cell RNA-sequencing analysis of human blood and tissue Spatial... by Jeongin Song, Minji Kang, Yunyoung Jang, Christine Suh-Yun Joh, Ha Yeon Shin, Julia Young Baik, Hyun Seung Choi, Kyu Hong Kim, Seong Min Lee, Seung-Min Cha, Hyunah Ku, Ahram Han, Sang Il Min, Jongwon Ha, Kyung Chul Moon, Sehoon Park, Seung Seok Han, Hajeong Lee, Dong Ki Kim, Kook Hwan Oh, Kwon Wook Joo, Ji Hwan Moon, Chung-Gyu Park, Yon Su Kim, Seung Hee Yang, Hyun Je Kim, Yong Chul Kim

“…Abstract Acute T cell-mediated rejection (TCMR) is one of the most important causes of kidney graft injury and loss; however, in-depth transcriptomic analyses of relevant tissues and circulating immune cells are limited. …”
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Research on the pathogen causing root rot on Phyllanthus emblica from the perspectives of identification, bionomics, fungicide sensitivity assay, and transcriptome analysis under d... by Yiming Zhang, Minyan Song, Minyan Song, Yonghong He, Yehua Si

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Cell deconvolution-based integrated time-series network of whole blood transcriptome reveals systemic antiviral activities and cell-specific immunological changes against PRRSV inf... by Byeonghwi Lim, Chiwoong Lim, Min-Jae Jang, Young-Jun Seo, Do-Young Kim, Christopher K. Tuggle, Kyu-Sang Lim, Jun-Mo Kim

“…The findings provide comprehensive insights into host responses to PRRSV infection, including diagnostic biomarkers.…”
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Impact of stocking density on oxidative stress, digestive enzyme activity, ATPase function, and transcriptomic changes in juvenile Crimson snapper (Lutjanus erythropterus) during l... by Jiaqi Su, Yu Guo, Jiayang Li, Karsoon Tan, Chuanxin Qin

“…This study aimed to assess how stocking density affects antioxidative stress, digestive enzymes, ATPases, and the transcriptome of Lutjanus erythropterus during long-hour transportation. …”
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Transcriptome analysis of PDGFRα+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFRα+ cell hyperplasia. by Se Eun Ha, Moon Young Lee, Masaaki Kurahashi, Lai Wei, Brian G Jorgensen, Chanjae Park, Paul J Park, Doug Redelman, Kent C Sasse, Laren S Becker, Kenton M Sanders, Seungil Ro

“…We have previously reported the transcriptomes of SMC and ICC. To complete the SIP cell transcriptome project, we obtained transcriptome data from jejunal and colonic PDGFRα+ cells. …”
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Effects of realgar-indigo naturalis formula on a zebrafish tumor xenograft model induced by human acute promyelocytic leukemia cells: antitumor activity, hepatotoxicity, and transc... by Donghan Bai, Zihao Zhang, Jingyue Gao, Qiaochu Wang, Remy Macdonald, Ziwen Xu, Shumin Chen, Nanxi Huang, Lu Luo, Lu Luo

“…Anti-tumor efficacy was assessed via pharmacodynamic analysis. Transcriptomic analysis further elucidated gene expression profiles, differentially expressed genes, and relevant biological pathways.ResultsRIF significantly reduced tumor cell fluorescence intensity, demonstrating anti-tumor efficacy. …”
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Transcriptome Analysis of <i>Aureobasidium pullulans</i> YQ65 Grown on Yeast Extract Peptone Glucose and Potato Dextrose Agar Media and Quantification of Their Effects on Pullulan... by Wan Wang, Jiyun Zhao, Kai Zhang, Zhengran Wang, Jingqiu Ma, Qian Yang, Congyu Lin

“…The transcriptome results were further validated by assessing the expression of specific genes. …”
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