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Heterogenous cancer-associated fibroblasts related tumor microenvironment marked by CD10/KLF4/TIAM1 were identified in pancreatic adenocarcinoma by integrated transcriptomics
Published 2025-04-01“…By utilizing multiplex immunohistochemistry and spatial transcriptomics, we also identified key CAF subpopulations, such as iCAF_17, iCAF_19, and myCAF_12, which were found to interact closely with tumor cells and macrophages. …”
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Unveiling Stage-Specific Flavonoid Dynamics Underlying Drought Tolerance in Sweet Potato (<i>Ipomoea batatas</i> L.) via Integrative Transcriptomic and Metabolomic Analyses
Published 2025-08-01“…Transcriptome analysis identified 8292 and 13,509 differentially expressed genes in DS1 and DS2, respectively, compared with the well-watered control (75 ± 5% field capacity). …”
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Comparative Transcriptome Analysis Reveals the Mechanism by Ethylene and 1-Methylcyclopropene Treatment on the Vase Life of Cut <i>Oncidium hybridum</i> ‘<i>Honey Angle</i>’
Published 2025-04-01“…The petal changes, vase life, and transcriptomic analysis after treatments were investigated. …”
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Seed coat transcriptomic profiling of 5-593, a genotype important for genetic studies of seed coat color and patterning in common bean (Phaseolus vulgaris L.)
Published 2025-03-01“…Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis revealed that phenylpropanoid biosynthesis, flavonoid biosynthesis, and plant hormone signal transduction comprised the principal pathways expressed during bean seed coat pigment development. Transcriptome analysis suggested that most structural genes for flavonoid biosynthesis and some potential regulatory genes were significantly differentially expressed. …”
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1866
Identification of key genes involved in collagen hydrogel-induced chondrogenic differentiation of mesenchymal stem cells through transcriptome analysis: the role of m6A modificatio...
Published 2024-07-01“…In conclusion, our study provides valuable insights into the molecular mechanisms of collagen hydrogel-induced chondrogenic differentiation of BMSCs, which may aid in developing more effective strategies for cartilage regeneration. …”
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1867
Transcriptomic analysis of the interactions between Fibrobacter succinogenes S85, Selenomonas ruminantium PC18 and a live yeast strain used as a ruminant feed additive
Published 2025-08-01“…Interactions were studied through RNA-seq transcriptomic analysis of various microbial combinations, alongside substrate consumption and metabolite production measurements. …”
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Comparative transcriptomic analysis of Rosa sterilis inflorescence branches with different trichome types reveals an R3-MYB transcription factor that negatively regulates trichome...
Published 2022-10-01“…Comparative transcriptomic analysis showed that many transcription factors (TFs) are potentially involved in the formation and development of trichomes. …”
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Novel insights into the Leishmania infantum transcriptome diversity of protein-coding and non-coding sequences in both stages of parasite development using nanopore direct RNA sequ...
Published 2025-07-01“…Our findings advance knowledge on existing Leishmania expression datasets and provide new insights into the transcriptome complexity and dynamics of both protein-coding and non-coding sequences throughout the parasite development.…”
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Transcriptome analysis of the early maturity mechanism of the rice cultivar ‘Yongxian 15’(基于转录组的水稻‘甬籼15’早熟机制解析)
Published 2025-04-01“…In this study, we conducted a series of transcriptome analyses on ‘Yongxian 15’ (early-maturing) and ‘Zhongzao 39’ (medium-maturing) during critical stages of spikelet differentiation. …”
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Comparative transcriptome reveals genes regulating root hair length of barley(基于比较转录组发掘控制大麦根毛长度的基因)
Published 2025-04-01“…In this study, by analyzing the transcriptome of barley roots which exhibiting significant differences in root hair length, we identified 274 shared differentially expressed genes. …”
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Contrasting gene expression patterns during floral induction in two Chenopodium ficifolium genotypes reveal putative flowering regulators
Published 2025-12-01“…Owing to its reproducible germination and seedling development, it becomes a promising model for studying floral induction, providing a basis for the comparison with C. quinoa. …”
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Immunotranscriptomic Profiling of <i>Spodoptera frugiperda</i> Challenged by Different Pathogenic Microorganisms
Published 2025-03-01“…This study elucidates the immune transcriptome of <i>S. frugiperda</i> in response to various pathogenic microorganisms, providing valuable insights for improving the effectiveness of existing microbial agents and developing new, highly efficient, and specific biopesticides.…”
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Evaluation of reference genes for gene expression analysis in Japanese flounder (Paralichthys olivaceus) under temperature stress
Published 2025-02-01“…Conclusion This study transcriptome-wide identified reference genes in different tissues of Japanese flounder exposed to temperature stress for the first time, providing a basis for gene expression research in flatfish.…”
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De novo transcriptome assembly of Aureobasidium melanogenum CGMCC18996 to analyze the β-poly(L-malic acid) biosynthesis pathway under the CaCO3 addition
Published 2023-07-01“…In this study, we sequenced the transcriptome of strain Aureobasidium melanogenum under 20 g/L CaCO3 addition. …”
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Novel Clinical Insights into the Pathogenesis of Posttraumatic Elbow Stiffness: An Expression Profile Analysis of Contracted Joint Capsule in Human
Published 2025-01-01“…This study aims to identify differentially expressed genes (DEGs) and elucidate molecular networks of posttraumatic elbow stiffness, providing novel insights into disease mechanisms at transcriptome level.Methods: Global transcriptome sequencing was conducted on six capsular samples from individuals with posttraumatic elbow stiffness and three control capsular samples from individuals with elbow fractures. …”
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