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Functional Differentiation Reconfiguration in the Midgut of <i>Nezara viridula</i> (Hemiptera: Pentatomidae) Based on Transcriptomics: Multilayer Enrichment Analysis and Topologica...
Published 2025-06-01“…The established multi-level analytical framework provides a robust methodology for subsequent dissection of complex biological systems, identification of key molecular targets for functional validation, and for the development of novel pest control strategies.…”
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Primary metabolomics and transcriptomic techniques were used to explore the regulatory mechanisms that may influence the flavor characteristics of fresh Corylus heterophylla × Cory...
Published 2025-01-01“…To explore the flavor related regulatory mechanisms of fresh Corylus heterophylla × Corylus avellana, a joint analysis of metabolome and transcriptome were utilized to compare the two typical C. heterophylla × C. avellana varieties with different flavors (‘yuzhui’ and ‘pingou21’) in this paper. …”
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Transcriptomic analysis of liquid non-sporulating Streptomyces coelicolor cultures demonstrates the existence of a complex differentiation comparable to that occurring in solid spo...
Published 2014-01-01“…The aim of this work was to compare the transcriptomes of S. coelicolor growing in liquid and solid cultures, deepening the knowledge of Streptomyces differentiation. …”
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A single-cell transcriptomic atlas of all cell types in the brain of 5xFAD Alzheimer mice in response to dietary inulin supplementation
Published 2025-05-01“…Conclusions These results provide a comprehensive overview on the transcriptomic changes in individual cells of the entire mouse brain in response to high fiber intake and a resourceful foundation for future mechanistic studies on the influence of diet and gut microbiome on the brain during neurodegeneration.…”
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Integrated Transcriptomics and Metabolomics Reveal Key Genes and Metabolic Pathway in Flower and Fruit Color Formation of <i>Cerasus humilis</i> (Bge.) Sok
Published 2025-04-01“…Further metabolomic and transcriptomic correlation analyses identified that <i>ChMYB9</i> and <i>ChMYB12</i> exhibited strong positive associations with anthocyanin pathway metabolites in both floral and fruit tissues. …”
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Transcriptome analysis reveals glycometabolism and antioxidation-related genes involved in the antifungal immune response of Spodoptera frugiperda larvae against Beauveria bassiana...
Published 2024-09-01“…This study enhances our understanding of the molecular mechanisms related to regulation of metabolism and provides a basis for exploring new methods to combat antifungal resistance in S. frugiperda.…”
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Integrating Clinical and Transcriptomic Profiles Associated with Vitamin D to Enhance Disease-Free Survival in Cervical Cancer Recurrence Using the CatBoost Algorithm
Published 2025-06-01“…<b>Methods</b>: A transcriptomic analysis of CaSki cervical cancer cells using data from the GEO dataset GSE267715 identified that vitamin D controls genes that prevent cervical cancer recurrence. …”
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Differential transcriptome analysis of different resistant citrus varieties infected with wild-type and toxin synthesis-impaired strains causing Alternaria brown spot
Published 2023-12-01“…In conclusion, the molecular regulatory mechanisms and key functional genes involved in the response of citrus varieties to ACT are preliminarily clarified, which provide a theoretical basis for the molecular breeding of citruses against Alternaria brown spot.…”
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Transcriptomic Insights into Salt Stress Tolerance Mechanisms in <i>Melia azedarach</i>: 24-Epibrassinolide-Mediated Modulation of Auxin and ABA Signaling Pathways
Published 2025-07-01“…Transcriptomic analysis identified 11,747 differentially expressed genes (DEGs) in the salt-treated versus control seedlings (SA vs. …”
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Genome-wide association study and transcriptomic analysis reveal the crucial role of sting1 in resistance to visceral white-nodules disease in Larimichthys polyactis
Published 2025-04-01“…Then, the integration of GWAS and transcriptome analysis identified seven key genes associated with resistance to VWND. …”
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Comprehensive Transcriptomic Analysis of Brain Tissues From the Infarcted Area of MCAO Rats Revealed That Acupuncture Attenuates Brain Injury via the Complement System
Published 2025-08-01“…ABSTRACT Objective This research focused on investigating acupuncture's effect on brain injury in middle cerebral artery occlusion (MCAO) rats and elucidating its potential mechanisms, with a focus on transcriptomic and protein‐level changes related to the complement system, which may be involved in acupuncture's therapeutic effects. …”
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Phenotypic and transcriptomic analysis reveals key genes associated with plant height in rubber tree and functional characterization of the candidate gene HbFLA11
Published 2025-06-01“…These results suggest that HbFLA11 is involved in gibberellin signaling and cell wall biosynthesis, thereby regulating plant growth. This study provides valuable genetic resources and research foundations for targeted trait breeding in rubber tree.…”
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Transcriptomic analysis reveals candidate molecular pathways involved in pea (Pisum sativum L.) resistance to pea aphid (Acyrthosiphon pisum Harris) biotypes
Published 2025-07-01“…This locus confers partial resistance to the pea-adapted and non-adapted A. pisum biotypes. Transcriptomic analyses of pea genotypes with and without aphid infestation revealed 9,217 differentially expressed genes in pea genotypes infested with the pea-adapted aphids, while fewer genes, 1,561 genes total, were expressed in response to the pea non-adapted aphids. …”
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Single-cell transcriptomics and time-series metabolite profiling reveal the spatiotemporal regulation of flavonoid biosynthesis genes and phytohormone homeostasis by PAP1 in Arabid...
Published 2025-07-01“…By comparing single-cell transcriptomes of the pap1-D mutant and wild-type plant leaves, we constructed a cell-type-specific atlas of gene expression and high-resolution dynamics of metabolites across developmental stages. …”
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Integrative Transcriptome and Metabolome Analysis Reveals Candidate Genes Related to Terpenoid Synthesis in <i>Amylostereum areolatum</i> (<i>Russulales: Amylostereaceae</i>)
Published 2025-05-01“…Metabolome (solid-phase microextraction (SPME) combined with gas chromatography–mass spectrometry (GC-MS) and liquid chromatography–mass spectrometry (LC-MS)) and transcriptome (Illumina NovaSeq) profiles were integrated to investigate terpenoid–gene correlations. …”
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