Regulatory mechanism of carbohydrate metabolism pathways on oil biosynthesis of oil plant Symplocos paniculata by Wenbin Zeng, Beilei Xie, Yunzhu Chen, Jingzhen Chen, Peiwang Li, Lijuan Jiang, Changzhu Li, Qiang Liu, Yan Yang

“…The mechanism underlying oil synthesis in oil plant fruits remains elusive, as sugar metabolism provides the essential carbon skeleton without a clear understanding of its intricate workings. …”
Get full text

Synergistic Response Mechanisms in Rice Seedlings Exposed to Brown Planthopper Infestation and High-Temperature Stress by Danyun Cao, Yuchen Ping, Yiru Lin, Jinyan Hu, Zimeng Wang, Wei Yuan, Tongtong Li, Linxin Liu, Bo Zhang, Shijiao Xiong, Cong Dang, Dawei Xue

“…And several candidate genes, including <i>Loc_Os01g02170</i> and <i>Loc_Os01g59870</i>, were identified that may play crucial roles in simultaneously regulating rice resistance to BPH and high-temperature stress. This research will provide new gene resources for cultivating rice with compound traits and provide ideas for the mechanism analysis of rice response to multiple stresses.…”
Get full text

MiRNA-mRNA integration analysis of three continuous embryonic stages of Chinese horseshoe crab Tachypleus tridentatus by Yunfan Huang, Ying Qiao, Shengping Zhong, Xingzhi Zhang, Menghong Hu, Kityue Kwan, Theerakamol Pengsakul, Jiasen Guo, Xuyang Chen, Xiaowan Ma, Qiongzhen Li

“…It provides a general overview of global gene expression changes during horseshoe crab’s early development. …”
Get full text

Feeding disruptions lead to a significant increase in disease modules in adult mice by Xiaoqin Mou, Pengxing Nie, Renrui Chen, Yang Cheng, Guang-Zhong Wang

“…Here, we investigate this hypothesis using transcriptomic data from a large cohort of adult mice subjected to feeding disruptions. …”
Get full text

Physiological and molecular mechanisms of nitrogen in alleviating drought stress in Phoebe bournei by Jing An, Honghao Huo, Qiyuan Liu, Yunli Jiang, Hong Luo, Yupei Hao

“…Abstract To explore the mechanisms by which nitrogen alleviates drought stress in Phoebe bournei, this study integrated drought treatment with exogenous nitrogen application to assess physiological characteristics and employed transcriptome sequencing to decipher transcriptional responses. …”
Get full text

Silver carp muscle hydrolysate ameliorated atherosclerosis and liver injury in apoE-/- mice: the modulator effects on enterohepatic cholesterol metabolism by Kai Wang, Zixin Fu, Yuqing Tan, Hui Hong, Jianping Wu, Yongkang Luo

Get full text

Energy status regulated umami compound metabolism in harvested shiitake mushrooms (Lentinus edodes) with spores triggered to release by Rongrong Xia, Xuemei Zhao, Guang Xin, Libin Sun, Heran Xu, Zhenshan Hou, Yunting Li, Yafei Wang

Get full text

Genome-wide analysis of the CBF gene family and their transcriptional response to cold stress in Hibiscus mutabilis by Shiye Sang, Yuqiao Zhou, Yiqiong Liu

Get full text

Combined metabolic phenotypes and gene expression profiles revealed the formation of terpene and ester volatiles during white tea withering process by Xuming Deng, Jun Wu, Tao Wang, Haomin Dai, Jiajia Chen, Bo Song, Shaoling Wu, Chenxi Gao, Yan Huang, Weilong Kong, Weijiang Sun

“…To study the mechanism underlying aroma changes during the white withering, we herein conducted volatile metabolomics and transcriptomics of the young leaves from the 'Fuding Dahaocha' tea cultivar. …”
Get full text

Molecular and Physiological Responses of <i>Litopenaeus vannamei</i> to Nitrogen and Phosphorus Stress by Qianqian Zhao, Cun Wei, Jiangling Dou, Yue Sun, Qifan Zeng, Zhenmin Bao

“…The results demonstrate that <i>L. vannamei</i> initiates oxidative and immune responses to cope with environmental stressors, but the adaptive capacity remains limited. These findings provide a foundation for understanding the stress tolerance mechanisms in shrimp and inform future strategies for breeding high-resistance strains in aquaculture.…”
Get full text

Xylem Parenchyma Anatomy and Gene Expression Patterns Indicate Mechanisms of Cavitation Resistance in Eucalyptus grandis During Drought by Rafael Keret, Paul N. Hills, David M. Drew

“…In parallel, genes associated with osmotic regulation, including various sugars, myo‐inositol, and metal ion transporters, were also induced, indicating putative solute‐mediated mechanisms for refilling embolized vessels. This transcriptomic response appears to be primarily triggered by oxidative and hypoxic stress signals. …”
Get full text

Unveiling the Cold Acclimation of Alfalfa: Insights into Its Starch-Soluble Sugar Dynamic Transformation by Lin Zhu, Zhiyong Li, Xiaoqing Zhang, Guomei Yin, Siqi Liu, Jinmei Zhao, Ying Yun, Maowei Guo, Jiaqi Zhang

“…The process is accompanied by CBF/DREB1A TF regulation. This study provides important insights into the cold acclimation mechanisms of alfalfa.…”
Get full text

Anti-Inflammatory Pathways Modulated by Microbial Polysaccharides from Euganean Thermal Muds in Zebrafish by Micol Caichiolo, Raffaella Margherita Zampieri, Francesca Terrin, Annachiara Tesoriere, Fabrizio Caldara, Nicoletta La Rocca, Paolo Martini, Luisa Dalla Valle

“…In this study, to investigate the underlying mechanisms of inflammation resolution, we performed a transcriptome analysis on zebrafish larvae inflamed with copper sulphate and treated with M-PS. …”
Get full text

GTSE1-expressed osteoblastic cells facilitate formation of pro-metastatic tumor microenvironment in osteosarcoma by Linzhu Wang, Wenyue Li, Weihang Ji, Danyang Bing, Mingyue Liu, Kaidong Liu, Bo Chen, Zhangxiang Zhao, Yunyan Gu, Xuelian Li, Xiaoqiang E, Lei Yang

“…Our findings suggest that GTSE1 overexpression serves as a potential biomarker for metastasis in osteosarcoma and provides a promising strategy to prevent metastasis by targeting GTSE1+ OB cells.…”
Get full text

Comparison of lignin degradation and flavor compound formation in roasted tobacco by two Bacillus subtilis strains by Junmin Wang, Teng Long, Zhenkun Jiang, Wenjun Mu, Mingliang Su, Li Ni, Shunhua Ji, Yuqing Wang, Kangxi Zhou, Renfeng Zhan, Lixuan Nie, Jingjing Li, Xingchuan Hu, Wei He, Wen Zhang

“…This study provides a preliminary elucidation of the potential mechanism by which YY-10 enhances the quality of tobacco leaves through lignin-degrading enzyme production, thus establishing a research foundation for the subsequent treatment of waste tobacco raw materials and industrial applications.…”
Get full text

Single-Cell RNA Sequencing Reveals an Atlas of Meihua Pig Testis Cells by Mao Zhang, Yiming Yan, Guoliang Peng, Shuang Gao, Hongyi Li, Yuan Li

“…To characterize the transcriptomic landscape of porcine spermatogenesis and identify potential marker genes for spermatogonia, an unbiased transcriptomic study of spermatogenesis in neonatal and sexually mature six-month-old Meihua pigs was performed using 10× Genomics single-cell RNA sequencing (scRNA-seq). …”
Get full text

Subpopulation-specific gene expression in Lachancea thermotolerans uncovers distinct metabolic adaptations to wine fermentation by Javier Vicente, Santiago Benito, Domingo Marquina, Antonio Santos

“…Additionally, differences in other metabolites of oenological interest as glycerol or aroma compounds production are highlighted. Here, we provide insights into the evolutionary processes shaping the transcriptomic diversity of L. thermotolerans, emphasizing the impact of winemaking environments on driving specific metabolic adaptations, including lactic acid production.…”
Get full text

A multi-omics approach for understanding blood digestion dynamics in Ixodes scapularis and identification of anti-tick vaccine targets by Jeremiah B. Reyes, Molly McVicar, Saransh Beniwal, Arvind Sharma, Richard Tillett, Juli Petereit, Andrew Nuss, Monika Gulia-Nuss

Get full text

Immune Dysregulation and Trophoblastic Dysfunction as a Potential Cause of Idiopathic Recurrent Pregnancy Loss by Sara Vasconcelos, Ana Costa Braga, Ioannis Moustakas, Bruno Cavadas, Mariana Santos, Carla Caniçais, Carla Ramalho, Susana M. Chuva de Sousa Lopes, Cristina Joana Marques, Sofia Dória

“…This study investigates the transcriptomic profiles of first-trimester products of conception (POC) from iPLs to uncover underlying molecular pathways. …”
Get full text

Changes in blood monocyte functional profile in breast cancer by A. A. Fedorov, E. A. Prostakishina, M. R. Patysheva, A. A. Frolova, P. S. Iamshchikov, I. V. Larionova, M. N. Stakheyeva, M. S. Dorofeeva, O. D. Bragina, E. L. Choynzonov, J. G. Kzhyshkowska, N. V. Cherdyntseva

“…CD14+16-, CD14+16+ and CD14-16+ monocytes subsets were obtained from blood by sorting. Whole transcriptome profling was provided in monocytes from patients and healthy females. …”
Get full text