Prp16 enables efficient splicing of introns with diverse exonic consensus elements in the short-intron rich Cryptococcus neoformans transcriptome by Manendra Singh Negi, Vishnu Priya Krishnan, Niharika Saraf, Usha Vijayraghavan

“…Furthermore, short (60–100nts) and ultrashort introns (<60nts) prevalent in the C. neoformans transcriptome were more sensitive to Prp16 knockdown than longer introns, indicating that Prp16 is required for the efficient splicing of short and ultrashort introns. …”
Get full text

Transcriptome Analysis Reveals the Role of Plant Hormone Signal Transduction Pathways in the Drought Stress Response of <i>Hemerocallis middendorffii</i> by Ying Qian, Haihang Yu, Siyu Lu, Yun Bai, Yuan Meng, Lifei Chen, Lin Wu, Yunwei Zhou

“…<i>middendorfii</i> and provides an importance for the systematic study of its drought-resistant molecular mechanism.…”
Get full text

Transcriptomics analysis identifies critical genes involved in the infection of crandell-reese feline kidney cell lines by feline panleukopenia virus by Shengnan SONG, Pan CHEN, Chuangfu CHEN, Jia GUO

“…To perform a comparative transcriptomic analysis of the gene expression profile in Crandell-Reese feline kidney (CRFK) cells following infection with the FPV-XJ-04 strain. …”
Get full text

Analysis of the whole transcriptome from gingivo-buccal squamous cell carcinoma reveals deregulated immune landscape and suggests targets for immunotherapy. by Richa Singh, Navonil De Sarkar, Sumanta Sarkar, Roshni Roy, Esita Chattopadhyay, Anindita Ray, Nidhan K Biswas, Arindam Maitra, Bidyut Roy

“…Here, we report a whole transcriptome profile on a batch of GBSCC tumours with diverse tobacco usage habits. …”
Get full text

Integrated physiological and transcriptomic analyses reveal the mechanism of reduction in wheat fertile floret number under spring low-temperature stress by Ying Weng, Zhiwei Tang, Weixiang Huang, Rui Wang, Feifei Wang, Hongmei Cai, Hao Wang, Zehao Liu, Baoqiang Zheng, Jincai Li, Xiang Chen

“…These findings enhance understanding of SLTS impacts on wheat floret development and provide insights for improving low-temperature tolerance and yield stability in wheat.…”
Get full text

Autophagy is involved in the toxicity of the biocontrol agent GC16 against Tetranychus pueraricola (Acari: Tetranychidae) based on transcriptomic and proteomic analyses by Yanyan He, Guangzu Du, Guang Wang, Huiming Guan, Shusheng Zhu, Bin Chen, Xiahong He, Youyong Zhu

“…This study reveals the molecular insecticidal mechanisms of GC16 and provides rationale for the field application of GC16 to control pest mites.…”
Get full text

Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease by Zachary Gaertner, Cameron Oram, Amanda Schneeweis, Elan Schonfeld, Cyril Bolduc, Chuyu Chen, Daniel Dombeck, Loukia Parisiadou, Jean-Francois Poulin, Rajeshwar Awatramani

Get full text

Dual-transcriptomics on microdissected cells reveals functional specialisation of symbiont-bearing-cells and contrasted responses to nutritional stress in the cereal weevil by Nikoletta Galambos, Nicolas Parisot, Agnès Vallier, Claudia Bevilacqua, Séverine Balmand, Carole Vincent-Monégat, Rita Rebollo, Benjamin Gillet, Sandrine Hughes, Abdelaziz Heddi, Anna Zaidman-Rémy

Get full text

Transcriptomic comparison between wild-caught and domesticated black tiger shrimp (Penaeus monodon) in early and late-vitellogenic broodstock females by Thanh Minh Nguyen, Nhut Minh Tran, Yen Thi Hai Tran, Tham Thi Hong Le, Long Minh Tran, Phuc Nguyen Thien Le, Abigail Elizur, Tomer Ventura, Thu Thi Minh Vo, Tuan Viet Nguyen

“…To understand their reproductive biology and maturation at a molecular level, we conducted a comprehensive transcriptomic analysis of P. monodon broodstock females from domestication and wild sources. …”
Get full text

Maize leaves salt-responsive genes revealed by comparative transcriptome of salt-tolerant and salt-sensitive cultivars during the seedling stage by Mingfang Ji, Sirui Xu, Zhongxian Ma, Chengnan Xiao, Jiangting Xu, Yanfang Zhu, Ronghao Cai, Chen Bo

“…To explore the molecular basis of these differences, we performed comparative transcriptome sequencing under varying salt treatment durations. …”
Get full text

Integrative analysis of bulk and single-cell transcriptomic data reveals novel insights into lipid metabolism and prognostic factors in hepatocellular carcinoma by Feiyu Qi, Guiming Zha, Yanfang Zhang, Sihua Liu, Yuhang Yang, Wanliang Sun, Dongdong Wang, Zhong Liu, Zheng Lu, Dengyong Zhang

“…This study investigated the status of lipid metabolism-related genes in HCC. Bulk transcriptomic and single-cell sequencing data for HCC were retrieved from public databases. …”
Get full text

Transcriptome Analysis Reveals the Molecular Mechanism Involved in Carotenoid Absorption and Metabolism in the Ridgetail White Prawn <i>Exopalaemon carinicauda</i> by Yumin Han, Yang Yu, Chengsong Zhang, Shihao Li, Jianbo Yuan, Fuhua Li

“…To clarify the molecular mechanism of astaxanthin utilization in <i>Exopalaemon carinicauda</i> (<i>E. carinicauda</i>), we conducted a comparative transcriptome analysis on the intestine, hepatopancreas, and muscle of <i>E. carinicauda</i>, fed with an astaxanthin diet and a normal diet. …”
Get full text

Elucidation of fruit cracking mechanism in bael [Aegle marmelos (L.) Correa.] using physico-biochemical and de novo transcriptomic approaches by Vasanth Vinayak Vara Prasad, V.B. Patel, M.K. Dhakar, Bikash Das, Sujit Kumar Bishi, V.P. Bhadana, G.P. Mishra, Vishal Mhetre, S.K. Singh, Vishal Nath, Ram Asrey, Devendra Pandey

“…The insights gained from this study provide a foundation for developing cracking-tolerant bael cultivars and formulating management strategies to mitigate fruit cracking in bael.…”
Get full text

Ephrin-B2 deletion in GABAergic neurons induces cognitive deficits associated with single-nucleus transcriptomic differences in the prefrontal cortex by Peijun Ju, Yu Fang, Siying Xiang, Weidi Wang, Ying Sun, Wei Wang, Yanli Ding, Chao Luo, Ping Jiang, Jianhua Chen

“…Comprehensive identification of cell-type-specific transcriptomic changes in EB2 knockout mice is expected to shed light on potential mechanisms associated with EB2 signaling in cognitive functions. …”
Get full text

Effect of Dead-Cell <i>Limosilactobacillus ingluviei</i> on Hematological Parameters and Jejunal Transcriptome Profile in Calves During the Weaning Period by Chao Ban, Supreena Srisaikham, Xingzhou Tian, Pipat Lounglawan

“…This study aimed to investigate the effect of dietary supplementation with a postbiotic from dead-cell <i>Limosilactobacillus ingluviei</i> C37 (postbiotic LIC37) on blood biochemical parameters and jejunal epithelium transcriptomic profiles in calves. Fourteen Holstein bull calves were randomly allocated into two groups (n = 7). …”
Get full text

Integration Analysis of Transcriptome Sequencing and Whole-Genome Resequencing Reveal Wool Quality-Associated Key Genes in Zhexi Angora Rabbits by Bohao Zhao, Yongqi Yu, Shaoning Sun, Jiawei Cai, Zhiyuan Bao, Yang Chen, Xinsheng Wu

Get full text

Integrative Metabolome and Transcriptome Analyses Reveal the Effects of Plucking Flower on Polysaccharide Accumulation in the Rhizomes of <i>Polygonatum cyrtonema</i> Hua by Huidong Yang, Hua Li, Jiahui Huang, Xincheng Liu, Zhongdong Hu, Yi Liu

“…In this study, we applied integrative metabolome and transcriptome analyses to investigate the accumulation of bioactive components in one-year-old (1Y) and six-year-old (6Y) rhizomes of <i>P. cyrtonema</i> Hua treated with a plucking flower. …”
Get full text

Identifying behavior regulatory leverage over mental disorders transcriptomic network hubs toward lifestyle-dependent psychiatric drugs repurposing by Mennatullah Abdelzaher Turky, Ibrahim Youssef, Azza El Amir

“…As food choices and daily habits play a fundamental role in this fluctuation, integrating machine learning with network medicine can provide valuable insights into disease systems and the regulatory leverage of lifestyle in mental health. …”
Get full text

Histological observation, transcriptome and methylome analyses reveal the dynamic changes during gonadal differentiation of spotted sea bass, Lateolabrax maculatus by Lingyu Wang, Haishen Wen, Xin Qi, Kaiqiang Zhang, Donglei Sun, Xueqi Li, Shaosen Yang, Yun Li

“…Collectively, this study provides a comprehensive overview of transcriptional and epigenetic mechanisms driving early gonadal differentiation in spotted sea bass, offering new insights into sex differentiation in teleosts.…”
Get full text

Salinity-induced virulence alteration of Aeromonas hydrophila isolated from Scatophagus argus: insights from transcriptomic profiling and phenotypic characterization by Yuan Sun, Lingyun Hao, Jianbing Liang, Shiyang Ye, Maoliang Su

Get full text