Comparative transcriptomics suggests a highly species-specific nature of the phenotypic plasticity associated with the outbreaks of the two main pest locusts by N. Bakkali, S. Saadi, A. Badih, M. Bakkali

“…The large set of genes that respond in a species-specific way provide material for comparing, understanding and tackling the locust’s phase change phenomenon in a species-specific way. …”
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Clinical Utility Findings of a Transcriptomic Psoriasis Biologic Test Demonstrate Altered Physician Prescribing Behavior and Improved Patient Outcomes by Bruce E. Strober, Michael Bukhalo, April W. Armstrong, David Pariser, Leon Kircik, Brian Johnson, Paul Montgomery, Tobin J. Dickerson

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Single-cell transcriptomics unveils molecular signatures of neuronal vulnerability in a mouse model of prion disease that overlap with Alzheimer’s disease by Jessy A. Slota, Lise Lamoureux, Kathy L. Frost, Babu V. Sajesh, Stephanie A. Booth

“…Our findings not only demonstrate the potential of single-cell transcriptomics to identify damage-vulnerable neurons, but also provide molecular insights into neuronal vulnerability and highlight commonalties across neurodegenerative disorders.…”
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L-Arabinose Alters the <i>E. coli</i> Transcriptome to Favor Biofilm Growth and Enhances Survival During Fluoroquinolone Stress by Katherine M. Austin, Jenna K. Frizzell, Audrey A. Neighmond, Isabella J. Moppel, Lisa M. Ryno

“…L-arabinose reduced the efficacy of levofloxacin and promoted growth in sub-minimum inhibitory concentrations (25 ng/mL). Transcriptomic analyses provided insight into the molecular basis of arabinose-mediated reduced susceptibility of <i>E. coli</i> to levofloxacin. …”
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Comparative transcriptome analysis and candidate gene mining for fire blight of Pear resistance in Korla fragrant Pear (Pyrus sinkiangensis Yü) by Yue Li, Yuanrong Ye, Wei Huan, Juan Ji, Jieyun Ma, Qiang Sheng, Jianfeng Lei

“…These research results provide a theoretical basis for a deeper understanding of the molecular mechanism of Korla fragrant pear resistance to fire blight and provide new genetic resources for the study of Korla fragrant pear resistance to fire blight.…”
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Single-cell transcriptomics reveals cellular dynamics and chemokine CXCL2-mediated smooth muscle cell proliferation in arterial repair by Xingxiao Huang, Xingxiao Huang, Yan Ping, Yan Ping, Qiuli Sun, Qiuli Sun, Mingjun Yu, Mingjun Yu, Chao Yang, Xiao Liu, Long Wang, Jinyu Huang, Jinyu Huang

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Metabolic pathway activation and immune microenvironment features in non-small cell lung cancer: insights from single-cell transcriptomics by Yanru Liu, Yanru Liu, Yanru Liu, Hanmin Liu, Hanmin Liu, Ying Xiong, Ying Xiong

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Integrative Analysis of Whole-Genome and Transcriptomic Data Reveals Novel Variants in Differentially Expressed Long Noncoding RNAs Associated with Asthenozoospermia by Maria-Anna Kyrgiafini, Maria Katsigianni, Themistoklis Giannoulis, Theologia Sarafidou, Alexia Chatziparasidou, Zissis Mamuris

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Integrated m6A RNA methylation and transcriptomic analysis of Apostichopus japonicus under combined high-temperature and hypoxia stress by Qiang Wang, Shuqing Zhang, Xiaohua He, Siyi Li, Xiaohui Xu, Yanwei Feng, Jianmin Yang, Guohua Sun

“…This study not only provides an important new perspective on the molecular stress recovery mechanism of marine invertebrates in the face of complex environmental stress, but it also provides theoretical support for aquaculture practice, assisting in the development of more stress-resistant aquaculture systems to deal with the severe challenges posed by global climate change.…”
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Transcriptome Analysis Reveals the Mechanism of Y0-C10-HSL on Biofilm Formation and Motility of <i>Pseudomonas aeruginosa</i> by Deping Tang, Yali Liu, Huihui Yao, Yanyan Lin, Yanpeng Xi, Mengjiao Li, Aihong Mao

“…In addition, the molecular mechanism of Y0-C10-HSL on <i>P. aeruginosa</i> biofilm formation was explored using transcriptome analysis. <b>Results:</b> At a concentration of 200 μmol/L Y0-C10-HSL, biofilm and exopolysaccharides were decreased by 38.5% and 29.3%, respectively; Y0-C10-HSL effectively dispersed the pre-formed biofilm and inhibited the motility ability of <i>P. aeruginosa</i>; and the <i>C. elegans</i> survival assay showed that Y0-C10-HSL was safe and provided protection to <i>C. elegans</i> against <i>P. aeruginosa</i> infection (the survival rates of <i>C. elegans</i> were higher than 74% and increased by 39%, 35.1%, and 47.5%, respectively, when treated with 200 μmol/L Y0-C10-HSL at 24, 48, and 80 h). …”
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Synergistic interaction between wheat streak mosaic virus and Triticum mosaic virus modulates wheat transcriptome to favor disease severity by Haritha Nunna, Nathan A. Palmer, Gautam Sarath, Stephen N. Wegulo, Satyanarayana Tatineni, Satyanarayana Tatineni

“…There also appeared to be a connection between viral replication and plastid health, with stronger downregulation of genes needed for chloroplast functions and integrity and increased synergism between TriMV and WSMV. This study provides an overview of transcriptomic changes distinctly influenced by TriMV and WSMV either singly or in combination and provides a good correlation between specific transcription factors and genes associated with metabolism to observed phenotypic changes in plant growth and disease synergism.…”
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De novo leaf and root transcriptome analysis to identify putative genes involved in triterpenoid saponins biosynthesis in Hedera helix L. by Huapeng Sun, Fang Li, Zijian Xu, Mengli Sun, Hanqing Cong, Fei Qiao, Xiaohong Zhong

“…Here is reported the first study of global transcriptome analyses using the Illumina HiSeq™ 2500 platform for H. helix. …”
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The transcriptomic response to heat stress of a jujube (Ziziphus jujuba Mill.) cultivar is featured with changed expression of long noncoding RNAs. by Qing Hao, Lei Yang, Dingyu Fan, Bin Zeng, Juan Jin

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Unveiling Salt Tolerance Mechanisms and Hub Genes in Alfalfa (<i>Medicago sativa</i> L.) Through Transcriptomic and WGCNA Analysis by Fengdan Wang, Hanfu Wu, Mei Yang, Wen Xu, Wenjie Zhao, Rui Qiu, Ning Kang, Guowen Cui

“…Mantel test analysis revealed that these genes showed strong correlations with physiological indicators. This study will provide important insights for breeding salt-tolerant alfalfa varieties.…”
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Targeted metabolome and transcriptome analysis reveals the key metabolites and genes influencing blue–purple colour development in Clematis lanuginosa flowers by Renjuan Qian, Youju Ye, Xiaohua Ma, Handong Gao, Qingdi Hu, Jian Zheng

“…In this study, to explore the anthocyanin synthesis mechanism involved in flower colour formation in C. lanuginosa, metabolome, and transcriptome sequencing was performed at six flower development stages. …”
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A comprehensive study on the longissius dorsi muscle of Ashdan yaks under different feeding regimes based on transcriptomic and metabolomic analyses by Tong Wang, Xiaoming Ma, Qingbo Zheng, Chaofan Ma, Zhilong Zhang, Heping Pan, Xian Guo, Xiaoyun Wu, Min Chu, Chunnian Liang, Ping Yan

“…The experimental results increased our understanding of yak meat quality and provided data materials for subsequent deep excavation of the mechanism of yak meat quality.…”
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Coordinated transcriptomic and metabolomic responses in rice reveal lignin-based physical barriers as key mechanisms of nonhost resistance to rust fungi. by Ce Zhang, Liru Jian, Tao Guan, Yiping Wang, Huihui Pang, Yiqian Xu, Yaoyao Xing, Jiawen Wang, Zhensheng Kang, Jing Zhao

“…This study investigates the rice-Pst (Puccinia striiformis f. sp. tritici) interaction using integrated transcriptomic and metabolomic analyses to unravel the temporal dynamics of gene expression and metabolite changes associated with NHR. …”
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Morphological and Transcriptomic Analyses Reveal the Involvement of Key Metabolic Pathways in Male Sterility in <i>Chimonanthus praecox</i> (L.) Genotypes by Bin Liu, Huafeng Wu, Yinzhu Cao, Xiaowen Zheng, Haoxiang Zhu, Shunzhao Sui

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Transcriptomics integrated with metabolomics reveals the mechanism of CaCl2-HCl electrolyzed water-induced glucosinolate biosynthesis in broccoli sprouts by Cui Li, Shuhui Song, Yanan He, Haijie Liu

“…The results of this study provided new insights into the regulatory network of glucosinolates biosynthesis in broccoli sprouts under CHEW treatment.…”
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Genome-wide association studies and transcriptome analysis reveal novel genes associated with freezing tolerance in rapeseed (Brassica napus L.). by Guoqiang Zheng, Zigang Liu, Lixi Jiang, Qi Yang, Jiaping Wei, Zefeng Wu, Junmei Cui, Xiaoyun Dong, Xiaodong Cao, Xuezhen Yang, Ying Wang, Yongjie Gong, Ermei Sa, Xiaoxia Wang

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