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Telomere-to-telomere Phragmites australis reference genome assembly with a B chromosome provides insights into its evolution and polysaccharide biosynthesis
Published 2025-01-01“…Based on multi-tissue transcriptomic data, we identified structural genes in the biosynthetic pathway of pharmacologically active Phragmitis rhizoma polysaccharides with essential roles in rhizome development. …”
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1362
Identification of differentially expressed genes and proteins related to diapause in Lymantria dispar: Insights for the mechanism of diapause from transcriptome and proteome analys...
Published 2025-01-01“…This study elucidates the diapause mechanism of spongy moth at the gene and protein levels, providing theoretical insights into the early and precise prevention and control of spongy moth. …”
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1363
An annotated CNS transcriptome of the medicinal leech, Hirudo verbana: De novo sequencing to characterize genes associated with nervous system activity.
Published 2018-01-01“…Here, we generated the first de novo transcriptome assembly from the entire central nervous system of Hirudo verbana, with the goal of providing a molecular resource, as well as to lay the foundation for a comprehensive discovery of genes fundamentally important for neural function. …”
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1364
Integrating Molecular Perspectives: Strategies for Comprehensive Multi-Omics Integrative Data Analysis and Machine Learning Applications in Transcriptomics, Proteomics, and Metabol...
Published 2024-10-01“…With the advent of high-throughput technologies, the field of omics has made significant strides in characterizing biological systems at various levels of complexity. Transcriptomics, proteomics, and metabolomics are the three most widely used omics technologies, each providing unique insights into different layers of a biological system. …”
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1365
Development of a MVI associated HCC prognostic model through single cell transcriptomic analysis and 101 machine learning algorithms
Published 2025-03-01“…Lastly, we investigated immunotherapy responses and drug sensitivities between risk groups, providing novel therapeutic insights for liver cancer.…”
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1367
A Novel Method to Profile Transcripts Encoding SH2 Domains in the <i>Patiria miniata</i> Mature Egg Transcriptome
Published 2024-11-01“…This work furthers research into egg activation by providing possible target proteins for future experiments and a novel method for identifying specific proteins of interest within a de novo transcriptome.…”
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1368
Transcriptomic Analysis of the Spleen from Asian Seabass (<i>Lates calcarifer</i>) Infected with Infectious Spleen and Kidney Necrosis Virus
Published 2025-05-01“…Next-generation sequencing identified differentially expressed genes, providing a comprehensive overview of the transcriptional landscape in the spleen of ISKNV-infected fish. …”
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1369
Molecular mechanisms of flowering time differentiation revealed by transcriptomic sequencing and de novo analysis in Chinese invasive populations of Ambrosia artemisiifolia
Published 2024-11-01“…Differentially expressed genes (DEGs) across sampling times and flowering time groups were identified through transcriptome sequencing and analyses of DGE and WGCNA, and were partially annotated to circadian rhythm, light response and hormone response through GO enrichment. …”
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Integrated physiological, biochemical and transcriptomic analyses elucidate the response of alpine plant Lamiophlomis rotata (Benth.) Kudo to Low-Nitrogen stress
Published 2025-07-01“…The species demonstrated nitrogen conservation strategies through enhanced assimilation and metabolic diversion into secondary biosynthesis, providing critical insights for alpine medicinal plant cultivation.…”
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1372
Unravelling turbot (Scophthalmus maximus) resistance to Aeromonas salmonicida: transcriptomic insights from two full-sibling families with divergent susceptibility
Published 2024-12-01“…Additionally, many DEGs overlapped with previously identified quantitative trait loci (QTLs) associated with resistance to A. salmonicida, providing further insights into the genetic basis of disease resistance. …”
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1373
Claroideglomus etunicatum enhances Pteris vittata L. arsenic resistance and accumulation by mediating the rapid reduction and transport of arsenic in roots
Published 2024-11-01“…To understand how AMF mediate P. vittata arsenic metabolism under arsenic stress, we performed P. vittata root transcriptome analysis before and after Claroideglomus etunicatum (C. etunicatum) colonization. …”
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Transcriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP)
Published 2025-01-01“…This study aimed to investigate the toxic effects of TCEP on turbot by integrating physio-biochemical and transcriptomic analyses. Results TCEP exposure induced severe neuroendocrine disrupting effects in turbot. …”
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1377
Genome-wide identification and transcriptome analysis of the cytochrome P450 genes revealed its potential role in the growth of Flammulina filiformis
Published 2025-04-01“…Conclusions These results provide a foundation for further exploration of the molecular evolution mechanism and potential functions of the CYP450 genes of F. filiformis in the regulation of growth and development.…”
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1378
Liver Transcriptome Analysis Reveals a Potential Mechanism of Heat Stress Increasing Susceptibility to <i>Salmonella</i> Typhimurium in Chickens
Published 2025-06-01“…By integrating inflammatory phenotypes, liver transcriptome profiles, and weighted gene co-expression network analysis (WGCNA), we systematically investigated the key regulatory factors through which heat stress affects host susceptibility to <i>Salmonella</i>. …”
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Integrated Metabolome and Transcriptome Analysis Reveals the Key Bitter Substances of <i>Pleioblastus amarus</i> Shoots at Different Developmental Stages
Published 2024-10-01“…This research highlights key compounds and genes related to bitterness, providing a basis for future research on enhancing the nutritional value and flavor of <i>P. amarus</i> shoots.…”
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Comprehensive transcriptomic and metabolomic analyses reveal developmental changes in one-year-old and two-year-old Polygonatum cyrtonema hua
Published 2025-06-01“…Overall, this study study integrates multi-omics techniques to demonstrate age-related changes in metabolites and genes profiles in P. cyrtonema, providing valuable insights for the identification of candidate genes involved in the biosynthesis of active substances.…”
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