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1281
Comparative transcriptome analysis reveals differences in immune responses to copper ions in Sepia esculenta under high-temperature conditions
Published 2025-03-01“…In this study, we used transcriptomic techniques to investigate the differences in Cu exposure immune responses in S. esculenta larvae under different temperature conditions. …”
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1282
Integration of whole genome resequencing and transcriptome sequencing to identify candidate genes for tall and short traits in Baicheng Fatty chickens
Published 2025-02-01“…Through the combined analysis of whole genome resequencing and transcriptome data, six intersecting genes were identified: KLF15, NRXN1, LOC107050638, MHCY11, HAO1, and BORCS6. …”
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1283
Integrating the Transcriptome and Proteome to Postulate That TpiA and Pyk Are Key Enzymes Regulating the Growth of <i>Mycoplasma Bovis</i>
Published 2024-10-01“…Transcriptomics and proteomics identified 193 DEGs and 158 DEPs, respectively, with significant differences in 49 proteins/34 transcriptomic CDS post-translational protein sequences (15 jointly up-regulated and 21 jointly down-regulated). …”
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1284
Comparison of muscle structure and transcriptome analysis of eyed-side muscle and blind-side muscle in Cynoglossus semilaevis (Osteichthyes, Cynoglossidae)
Published 2025-03-01“…Taken together, this study may provide useful information to understand the molecular mechanism of muscle development in flatfishes.…”
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1285
Effects of Estrogen and Estrogen Receptors on Transcriptomes of HepG2 Cells: A Preliminary Study Using RNA Sequencing
Published 2018-01-01“…Collectively, these differentially expressed genes across HepG2 cell transcriptome involving cellular and metabolic processes by E2 and ER agonists provided mechanistic insight into protective effects of estrogens in HCC development.…”
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1286
Identification of a deubiquitinating gene-related signature in ovarian cancer using integrated transcriptomic analysis and machine learning framework
Published 2025-04-01“…Methods We conducted an integrated analysis of single-cell RNA sequencing and bulk transcriptome data from public databases. DUB genes were identified through Genecard database. …”
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1287
A Strain Capable of Reducing Aflatoxin B1: Identification, Optimization of Removal Conditions and Transcriptomic Analysis of Degradation Pathways
Published 2025-06-01“…Transcriptomic results revealed that 525 genes were differentially expressed under the stress of AFB1, including 397 up-regulated and 128 down-regulated ones. …”
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1288
Core transcriptome network modulates temperature (heat and cold) and osmotic (drought, salinity, and waterlogging) stress responses in oil palm
Published 2024-12-01“…To understand the core abiotic stress transcriptome (CAST) of oil palm, we performed RNA-Seq analyses of oil palm leaves subjected to drought, salinity, waterlogging, heat, and cold stresses. …”
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1289
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1290
Ochratoxin A Degradation and Stress Response Mechanism of <i>Brevundimonas naejangsanensis</i> ML17 Determined by Transcriptomic Analysis
Published 2024-11-01“…ML17 could almost completely degrade 12 μg/mL of OTA within 36 h, converting it into the non-toxic OTα and L-phenylalanine. Transcriptomic analysis showed that 275 genes were upregulated, whereas three genes were downregulated in ML17 under the stress of 1 μg/mL OTA. …”
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1291
Decoding the Tissue-Specific Profiles of Bioactive Compounds in <i>Helvella leucopus</i> Using Combined Transcriptomic and Metabolomic Approaches
Published 2025-03-01“…Transcriptomic analysis revealed a higher expression of genes involved in sterol biosynthesis (<i>ERG1</i>, <i>ERG3</i>, <i>ERG6</i>) and energy metabolism (<i>PGK1</i>, <i>ENO1</i>, <i>PYK1</i>) in the cap, suggesting a more active metabolic profile in this tissue. …”
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1292
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1293
Utilizing Microbial Inoculants to Alleviate Continuous Cropping Obstacles: Insights into the Metabolites and Transcriptomic Responses of <i>Pinellia ternata</i>
Published 2025-03-01“…Correspondingly, transcriptomic analysis revealed the upregulation of phenylalanine ammonia-lyase (PAL) and other stress-related genes, confirming the metabolic shifts. …”
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1294
Transcriptome Sequencing Reveals Survival Strategies and Pathogenic Potential of <i>Vibrio parahaemolyticus</i> Under Gastric Acid Stress
Published 2025-04-01“…Interestingly, surviving <i>Vibrio parahaemolyticus</i> showed a significantly shorter growth lag time (LT) during recovery. Transcriptome sequencing (RNA-seq) analyses indicated that the bacteria adapted to gastric acid stress by regulating the two-component system through stress proteins secreted via the ribosomal pathway. …”
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1295
Transcriptomic Characterization of the Porcine Urinary Bladder Trigone Following Intravesical Administration of Resiniferatoxin: Insights from High-Throughput Sequencing
Published 2025-03-01“…Resiniferatoxin (RTX), a potent capsaicin analog, is being investigated as a therapeutic agent for neurogenic conditions, particularly those affecting bladder control. However, the transcriptomic effects of RTX on the urinary bladder remain largely unexplored. …”
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1296
Metabolic and Transcriptomic-Based Characterization of <i>Streptococcus salivarius</i> ssp. <i>thermophilus</i> Snew Fermentation in Milk
Published 2025-02-01“…<i>thermophilus</i> Snew-fermented milk, as well as transcriptomic and metabolomic analyses of different fermentation stages. …”
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1297
A Comparative Transcriptomic Study Reveals Temporal and Genotype-Specific Defense Responses to <i>Botrytis cinerea</i> in Grapevine
Published 2025-02-01“…This study investigates transcriptomic responses to <i>B. cinerea</i> in tolerant and susceptible grapevine genotypes using RNA sequencing (RNA-seq). …”
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1298
Transcriptomic and metabolomic analyses for the mechanism underlying anthocyanin synthesis during the growth and development of purple eggplant (Solanum melongena L)
Published 2025-05-01“…Metabolomic profiling identified anthocyanin types, while transcriptomic data highlighted differentially expressed genes. …”
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1299
Transcriptome and Metabolome Analyses of Flavonoid Biosynthesis During Berry Development of Muscadine Grape (<i>Vitis rotundifolia</i> Michx)
Published 2025-07-01“…Two muscadine genotypes (Paulk and Supreme) were investigated via metabolomic and transcriptomic analysis during three developmental stages (bunch closure, veraison stage, and ripening stage). …”
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1300
Mendelian randomization and transcriptomic analysis reveal a positive cause-and-effect relationship between Alzheimer's disease and colorectal cancer
Published 2025-01-01“…Conclusions: This study provides evidence of a causal relationship between AD and CRC, suggesting that shared genetic and inflammatory pathways may underlie both conditions. …”
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