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Integrative Metabolomic and Transcriptomic Analyses Reveal the Impact of Methionine Supplementation to Gibel Carp (<i>Carassius auratus gibelio</i>)
Published 2025-05-01“…The hepatopancreas transcriptomic (n = 4) and metabolomic (n = 6) analysis for the FM group and HM<sub>100</sub> group showed that the significantly differential metabolites mainly related to amino acid metabolism, protein digestion and absorption, and aminoacyl-tRNA biosynthesis. …”
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1263
Comparative genome and transcriptome analysis of the endophytic fungus Epichloë sibirica reveals biological control mechanism in host Achnatherum sibiricum
Published 2025-06-01“…This study elucidates the tripartite strategy employed by Epichloë sibirica to protect Achnatherum sibiricum through comparative genomics and transcriptomics. First, genomic and transcriptomic analyses revealed that E. sibirica can synthesize antibiotics (e.g., ε-poly-L-lysine) and mycelial degrading enzymes. …”
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1264
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1265
From the Gut to the Brain: Transcriptomic Insights into Neonatal Meningitis <i>Escherichia coli</i> Across Diverse Host Niches
Published 2025-05-01“…We performed a comparative transcriptomic analysis of NMEC RS218, the prototype strain of NMEC, under four distinct host-mimicking conditions: colonic fluid (CF), serum (S), human brain endothelial cells (HBECs), and cerebrospinal fluid (CSF). …”
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1267
Global transcriptome dynamics of seagrass flowering and seed development process: insights from the iconic seagrass Zostera marina L
Published 2025-03-01“…This study evaluated the morphological changes of the spathe during eelgrass sexual reproduction and analyzed global transcriptome dynamics across eight sequential stages. …”
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1268
Analysis of the CPZ/Wnt4 osteogenic pathway for high-bonding-strength composite-coated magnesium scaffolds through transcriptomics
Published 2024-10-01“…Moreover, this study provides a theoretical underpinning for the application and clinical translation of Mg-based scaffolds in bone tissue engineering endeavors.…”
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1269
Transcriptome analysis of genes and carbon partitioning pathways involved in high temperature stress resilience in groundnut (Arachis hypogaea L.)
Published 2025-08-01“…The genes response in both sensitive and tolerant genotypes at each stage can provide valuable insights for future investigations and the genetic improvement of groundnut for heat tolerance mechanisms.…”
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1270
Accumulation differences of high-value ingredients in different phenotype Lonicera macranthoides: insights from integrative metabolome and transcriptome analyses
Published 2025-03-01“…These lines of evidences provide a molecular basis for the metabolic changes occurring during growth and can be significantly implicated in further research on the biosynthetic pathways associated with high-value potent active components in woody plants. …”
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Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon black
Published 2025-04-01“…Conclusions These findings provide insights into the mechanisms of lung overload and inflammation in rats, and highlight similarities and differences in transcriptomic responses of rat and human alveolar macrophages.…”
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1273
Adaptive Evolution and Transcriptomic Specialization of P450 Detoxification Genes in the Colorado Potato Beetle Across Developmental Stages and Tissues
Published 2025-06-01“…This study conducted comprehensive transcriptome analysis across multiple developmental stages and tissues, focusing on the cytochrome P450 monooxygenase gene family. …”
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1274
Effects of defined voluntary running distances coupled with high‐fat diet consumption on the skeletal muscle transcriptome of male mice
Published 2025-01-01“…These results demonstrate that running distance impacts the adaptation of the skeletal muscle transcriptome to exercise and suggest that middle‐distance running may provide the greatest protection against high‐fat diet‐induced stress coupled with exercise.…”
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Aging-related alternative splicing drive neoantigen emergence revealed by transcriptome analysis of 1,255 human blood samples
Published 2025-05-01“…This study aimed to identify age-related genes and alternative splicing (AS) events by comprehensive transcriptome analysis of 1,255 healthy blood samples from individuals aged 8–87 years. …”
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Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer
Published 2025-04-01“…Immunogenic cell death-related features (ICDRs) were constructed using multiple machine algorithms, and ICDRs were evaluated in training and validation sets to provide quantitative tools for predicting prognosis in clinical practice. …”
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Transcriptomic insights into Mycobacterium orygis infection-associated pulmonary granulomas reveal multicellular immune networks and tuberculosis biomarkers in cattle
Published 2025-12-01“…This study delves into the comparative pathology and transcriptomic landscape of pulmonary granulomas in cattle naturally infected with M. orygis, using high-throughput RNA sequencing. …”
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