Elucidating roles of lipid remodeling and ion homeostasis in sustaining oyster allometric growth by Guixiang He, Tuo Yao, Yang Xu, Yuewen Deng, Yong Liu, Liqiang Zhao

“…Allometric growth provides a great opportunity for bivalve breeding programs. …”
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Integrative multi-omics analysis reveals the potential mechanism by which Streptomyces pactum Act12 enhances wheat root drought tolerance by coordinating phytohormones and metaboli... by Jinhui Zhang, Hongwei Wen, Shanshan Wang, Yuzhi Wang, Zeyu Wang, Xingwei Zheng, Jie Chen, Bin Yang, Hao Shan

“…The integrated analysis of the transcriptome and metabolome demonstrated that Act12 might promote root development through the synergistic regulation of phytohormone signaling. …”
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2-Acetamidophenol (2-AAP) Suppresses the Progression of Atherosclerosis by Alleviating Hyperlipidemia and Attenuating the Ferroptosis Pathway by Xiaohan Zang, Yongcheng Wang, Cong Han, Lishuang Cui, Haojie Liu, Shuimiao Tian, Kechun Liu, Peihai Li, Chen Sun, Qing Xia, Yun Zhang

“…Overall, our study demonstrated that 2-AAP demonstrated potential in AS by alleviating hyperlipidemia and attenuating the ferroptosis pathway and provided evidence supporting the future application of 2-AAP in AS treatment.…”
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Indole-3-Butyric Acid Enhances Root Formation and Alleviates Low-Temperature Stress in Sugarcane: Molecular Insights and Identification of Candidate Genes by Xiao-Qiu Zhang, Yong-Jian Liang, Xiu-Peng Song, Mei-Xin Yan, Li-Qiu Tang, Zhen-Qiang Qin, Yu-Xin Huang, De-Wei Li, Dong-Mei Huang, Ze-Sheng Shi, Bao-Qing Zhang, Dong-Liang Huang

“…This study demonstrated that IBA markedly promoted root initiation, elongation, and biomass under low temperature, and significantly increased the levels of phytohormones, including GA₃, ABA, JA, IAA, and ZT, suggesting the activation of multiple signaling pathways. Transcriptome analysis revealed numerous differentially expressed genes related to metabolic pathways such as glycolysis, the tricarboxylic acid cycle, and glutathione metabolism. …”
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Identification of new diagnostic targets for hepatitis B virus‐induced liver fibrosis by Ying Wang, Shuo Qin, Meng Yang, Xiaoling Wang

“…These results provide new insights for HBV‐induced liver fibrosis research and clinical treatment.…”
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Integrated Analysis of Survival, Physiological‐Biochemical, and Transcriptomic Changes Reveals the Impact of Saline Stress on the Freshwater Snail Pomacea canaliculata by Yingtong Chen, Fucheng Yao, Zhaoji Shi, Chunxia Zhang, Jimin Liu, Jiaen Zhang, Zhong Qin

“…Different levels of saline stress significantly affected the contents of free water, bound water, and enzyme activity of their eggs at different hatching stages. These findings provide theoretical support for understanding the saline tolerance of snails.…”
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Mechanisms of Amomum villosum essential oil in enhancing tilapia (Oreochromis niloticus) intestinal health by Xiangbing Zeng, Xiaoting Zheng, Chenghui Li, Junchao Ming, Hongbiao Dong, Jiasong Zhang

“…Hmgb2, Parp11, Bcoll is considered to be the key genes, and has the immune regulation function. This study provides new insights into the molecular basis underlying the protective effects of dietary EOA in tilapia. …”
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Multi-Omics Mining of Characteristic Quality Factors Boosts the Brand Enhancement of the Geographical Indication Product—Pingliang Red Cattle by Jing Liu, Yu Zhu, Xiaoxia Liu, Juan Zhang, Chuan Liu, Yan Zhao, Shuming Yang, Ailiang Chen, Jie Zhao

“…This study integrated metabolomic and transcriptomic analyses to elucidate the biochemical and physiological factors underlying the enhanced flavor, color stability, and tenderness of Pingliang Red Cattle beef compared to Qinchuan and Simmental cattle. …”
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Novel Insights from Comprehensive Bioinformatics Analysis Utilizing Large-Scale Human Transcriptomes and Experimental Validation: The Role of Autophagy in Periodontitis by Liu F, Zhu Z, Zou H, Huang Z, Xiao S, Li Z

“…These findings not only enhance our comprehension of the pathological mechanisms of periodontitis but also provide substantial evidence for the advancement of novel therapeutic strategies.Keywords: periodontitis, transcriptome, autophagy, key genes, diagnosis, database…”
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Effects of Methyl Farnesoate on the Growth and Antioxidant Capacity of <i>Neocaridina denticulata</i> by Ying Chen, Xiaojuan Sun, Jiahao Du, Jingjie Hu, Zhenmin Bao, Zhe Qu

“…Activities of AMS, LPS, Try and SOD generally decreased, whereas MDA levels and GSH-PX activity increased after 40 days of MF exposure. Moreover, transcriptomic analysis revealed that MF regulated various biological processes including growth, metabolism and immune responses. …”
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Whole-genome resequencing to investigate the genetic diversity and the molecular basis underlying key economic traits in indigenous sheep breeds adapted to hypoxic environments by Dehong Tian, Dehong Tian, Dehong Tian, Buying Han, Buying Han, Buying Han, Xue Li, Xue Li, Xue Li, Quanbang Pei, Baicheng Zhou, Kai Zhao, Kai Zhao

“…Integrating GWAS and transcriptomics, we pinpointed key wool trait genes, including WNT16 (non-synonymous mutations), PRKCA, MAP3K8, MMP7, OVOL2 (intergenic SNPs), and COL7A1, KDM8, ZNF385D (intronic SNPs). …”
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Physiological and Transcriptome Analysis Reveal the Underlying Mechanism of Salicylic Acid-Alleviated Drought Stress in Kenaf (<i>Hibiscus cannabinus</i> L.) by Hui Zhang, Guofeng Xu, Samavia Mubeen, Rujian Wei, Muzammal Rehman, Shan Cao, Caijin Wang, Jiao Yue, Jiao Pan, Gang Jin, Ru Li, Tao Chen, Peng Chen

“…In this study, the kenaf seedlings were subjected to physiological and transcriptomic analysis under control (CK), moderate drought stress (D), and moderate drought stress with 1 mM SA (D_SA). …”
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Multi-Omics Analyses Uncover the Mechanism Underlying Polyploidization-Enhanced Steviol Glycosides Biosynthesis in <i>Stevia rebaudiana</i> by Juan Liu, Jiaxue Wang, Mingjia Chen, Wenna Meng, Anping Ding, Miao Chen, Rongping Ding, Mingpu Tan, Zengxu Xiang

“…Overall, our results indicate the presence of a regulatory circuit orchestrated by polyploidization, which recruits beneficial rhizosphere microbes and modulates the expression of genes associated with SG biosynthesis, ultimately enhancing the SG content in stevia. This finding will provide new insights for promoting the propagation and industrial development of stevia.…”
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Long-term thermal acclimation enhances heat resistance of Hong Kong catfish (Clarias fuscus) by modulating gill tissue structure, antioxidant capacity and immune metabolic pathways by Cunyu Duan, Dayan Zhou, Ruiqing Feng, Xiaolong Li, Lei Yang, Xinyi Li, Guangli Li, Huapu Chen, Yu Liao, Changxu Tian

“…Subsequently, histological, biochemical, and transcriptomic changes in gill tissue were observed after exposure to acute high temperatures (34 ℃) and subsequent temperature recovery (26 ℃). …”
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Integrated physiological and transcriptomic analysis uncovers the mechanism of moderate nitrogen application on promoting the growth and (-)-borneol accumulation of Blumea balsamif... by Yuan Yuan, Wei-Jie Tang, Wei-Jie Tang, Jia-Yuan Cao, Ke Zhong, Ke Zhong, Ze-Jun Mo, Ying Zhou, Yu-Xin Pang, Yu-Xin Pang

“…Our study demonstrates that N can enhance the accumulation of (-)-borneol in B. balsamifera when applied in appropriate quantities. These findings provide a comprehensive understanding of the relationship between N nutrition and (-)-borneol yield in B. balsamifera, offering valuable insights for future cultivation practices.…”
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Analysis of Transcriptional and Metabolic Differences in the Petal Color Change Response to High-Temperature Stress in Various Chrysanthemum Genotypes by Zhimei Li, Hougao Zhou, Yan Chen, Minyi Chen, Yutong Yao, Honghui Luo, Qing Wu, Fenglan Wang, Yiwei Zhou

“…This study examines the mechanisms of color change in purple chrysanthemums under high-temperature stress using combined metabolomic and transcriptomic analyses. Four chrysanthemum varieties—two heat-stable (‘Zi Feng Che’ and ‘Chrystal Regal’) and two heat-sensitive (‘Zi Hong Tuo Gui’ and ‘Zi Lian’)—were analyzed. …”
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Sexually dimorphic gene expression responses of bovine embryos to the maternal microenvironment on day 13 of gestation by Dessie Salilew-Wondim, Ernst Tholen, Christine Große-Brinkhaus, Eva Held-Hoelker, Dennis Miskel, Franca Rings, Karl Schellander, Urban Besenfelder, Vitezslav Havlicek, Dawit Tesfaye, Michael Hoelker

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Investigating Overlapping Genetic Factors and Novel Causal Genes in Autoimmune Diseases: A Transcriptome-Wide Association and Multiomics Study by Leihua Fu, Jieni Yu, Xin Wang, Zhe Chen, Jiaying Sun, Feidan Gao, Zhijian Zhang, Jiaping Fu, Pan Hong, Weiying Feng

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Transcriptome-wide study of mRNAs modified by m6A RNA methylation in the testis development of dairy goats by Xinyang Ren, Yingxin Qu, Akang Shari, Guang Li

“…This study reports for the first time the mRNA profiles of m6A modifications across the entire transcriptome during testicular development in Guanzhong dairy goats, providing a new perspective for genetic improvement in goats.…”
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Combined Physiological and Transcriptomic Analyses of the Effects of Exogenous Trehalose on Salt Tolerance in Maize (<i>Zea mays</i> L.) by Jingyi He, Hongliang Tang

“…This study elucidates mechanisms for enhancing salt tolerance in maize, providing theoretical support for improving its resilience and offering innovative strategies for utilizing a wide range of saline-alkali land.…”
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