Biological mechanism of sex differences in mental rotation: Evidence from multimodal MRI, transcriptomic and receptor/transporter data by Haixia Long, Hao Wu, Chaoliang Sun, Xinli Xu, Xu-Hua Yang, Jie Xiao, Mingqi Lv, Qiuju Chen, Ming Fan

“…This study aimed to elucidate neural, genetic, and molecular bases of these disparities in mental rotation by integrating data from multimodal magnetic resonance imaging (MRI), transcriptomic and receptor/transporter. We first calculated the dynamic regional homogeneity (dReHo), gray matter volume (GMV) and fractional anisotropy (FA) in voxel-wise manner and parceled them into 246 brain regions based on Brainnetome Atlas. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

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Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma by Lei Yang, Qing Zhou, Bo Zhang, Yi-Long Wu, Zhi-Hong Chen, Wen-zhao Zhong, Fen Wang, Yun-Ting He, Song Dong, Xue-Wu Wei, Wei-Dong Chen, Xiao-Rong Yang, Xue-Meng Shang

“…Furthermore, EGFR-mutant LUAD had significantly less crosstalk between T cells and other cell types via programmed cell death-1 (PD-1) and PD-L1 or other immune checkpoints compared with EGFR wild-type LUAD.Conclusions Our findings provide a comprehensive understanding of the immune landscape of EGFR-mutant LUAD at the single-cell level. …”
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Combining QTL mapping and transcriptomics to identify candidate genes for cold tolerance during the budding and seedling stages in rice by Chun Ae Kim, Wenqiang Chen, Shuangbing Zhu, Guogen Zhang, Congcong Shen, Kai Chen, Xiuqin Zhao, Tianqing Zheng, Wensheng Wang, Jianlong Xu

“…A comprehensive analysis integrating QTL and transcriptome data from both stages revealed distinct differences in CT mechanisms, highlighting stage-specific variations. …”
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Exploring biomarkers and molecular mechanisms of Type 2 diabetes mellitus promotes colorectal cancer progression based on transcriptomics by Simin Luo, Yuhong Zhu, Zhanli Guo, Chuan Zheng, Xi Fu, Fengming You, Xueke Li

“…These mechanisms and molecular markers may provide new ideas for further studies of T2DM-promoted CRC progression and contribute to drug discovery for the treatment of co-morbidities.…”
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Combined Analysis of Transcriptome and Mendelian Randomization Reveals AKT1 and PPARG as Biomarkers Related to Glucose Metabolism in Sepsis by Ma J, Li W, Ma Q, Ding L, Wang Z, Wang R, Huang Y, Ma G, Gao J

“…AKT1 may inhibit sepsis development, while PPARG may promote it. These findings provide valuable insights for sepsis diagnosis and therapeutic drug development.Keywords: sepsis, glucose metabolism, transcriptomics, Mendelian randomization, biomarkers…”
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Transcriptome Profiling Reveals the Effects of Rootstocks on Scion Architecture in <i>Malus domestica</i> Borkh Var. ‘Harlikar’ by Bin Xie, Junhao Li, Jiangtao Zhou, Guodong Kang, Zhongwen Tang, Xiaojian Ma, Xin Li, Jing Wang, Yanzhen Zhang, Yanhui Chen, Sumiao Yang, Cungang Cheng

“…We also explored the mechanism of scion architecture formation using transcriptomics based on different scion/rootstock combinations. …”
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A Transcriptomic Approach to Sex Differences in Calcific Aortic Valve Stenosis in Patients with a Tricuspid Aortic Valve by Emma Le Nezet, MSc, Rose Tam, MSc, Zhonglin Li, MSc, Nathalie Gaudreault, BSc, Patrick Mathieu, MD, MSc, Nancy Côté, PhD, Isabelle Guisle, PhD, Sébastien Thériault, MD, MSc, Yohan Bossé, PhD, Marie-Annick Clavel, DVM, PhD

“…We thus aim to assess the transcriptome of stenotic aortic valves according to patients’ sex. …”
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Complementary Ribo-seq approaches map the translatome and provide a small protein census in the foodborne pathogen Campylobacter jejuni by Kathrin Froschauer, Sarah L. Svensson, Rick Gelhausen, Elisabetta Fiore, Philipp Kible, Alicia Klaude, Martin Kucklick, Stephan Fuchs, Florian Eggenhofer, Chao Yang, Daniel Falush, Susanne Engelmann, Rolf Backofen, Cynthia M. Sharma

“…Abstract In contrast to transcriptome maps, bacterial small protein (≤50-100 aa) coding landscapes, including overlapping genes, are poorly characterized. …”
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A chromosome-level Pinellia ternata genome assembly provides insight into the evolutionary origin of ephedrine and acrid raphide formation by Tao Xue, Haifeng Jia, Meng Wang, Yanting Zhang, Xiao Liu, Qiujie Chao, Fenglan Zhao, Zhuang Meng, Jianping Xue, Jishan Lin, Yongbo Duan

“…There are 14 lectin genes in the P. ternata genome, which were all highly expressed in the tuber, explaining the acrid raphide formation. These findings provide new insight into ephedrine biosynthesis and acrid raphide formation.…”
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Adaptation responses to salt stress in the gut of Poecilia reticulata by Hyerim Lee, Hyunjae Yeo, Jihye Park, Keunsoo Kang, Sun-Ju Yi, Kyunghwan Kim

“…Our findings highlight the intricate mechanisms of adaptation to salinity stress in P. reticulata, providing insights into osmoregulatory mechanisms involving the intestine in aquatic organisms.…”
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Conserved stress-responsive genes involved in the early development of Euterpe Edulis by Layra de Medeiros Cardozo, Francine Alves Nogueira de Almeida, Vinicius Sartori Fioresi, Guilherme Bravim Canal, Liana Hilda Golin Mengarda, Adésio Ferreira, Marcia Flores da Silva Ferreira

“…Using eight RNA-Seq libraries, the strategy was to obtain the first transcriptome for the species through reference mapping against the Elaeis guineensis genome, with focus on conserved genes, followed by differential expression and functional annotation analyses. …”
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Effects of dietary curcumin supplementation on growth performance, antioxidant capacity, and gene transcriptome in the juvenile Manila clam (Ruditapes philippinarum) by Yang Zhang, Hailong Huang, Kai Liao, Yuxiang Zhu, Yang Liu, Deshui Chen, Bin Ma, Hui Ge, Jilin Xu

“…This study evaluated the effects of dietary curcumin supplementation on growth performance, antioxidant capacity, and gene transcriptome in the juvenile clam (Ruditapes philippinarum). …”
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The integration of quantitative trait locus mapping and transcriptome studies reveals candidate genes for water stress response in St. Augustinegrass by Greta B.G. Rockstad, Xingwang Yu, Gabriel de Siqueira Gesteira, Susmita Gaire, Allison N. Dickey, Beatriz T. Gouveia, Ashley N. Schoonmaker, Amanda M. Hulse-Kemp, Susana R. Milla-Lewis

“…Augustinegrass, providing a foundation for targeted drought resistance breeding.…”
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Biochemical and Transcriptomic Analyses Reveal Key Salinity and Alkalinity Stress Response and Tolerance Pathways in <i>Salix linearistipularis</i> Inoculated with <i>Trichoderma</... by Zhouqing Han, Lili Chen, Wenyi Wang, Xueting Guan, Junjie Song, Shurong Ma

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Interferon-gamma rescues dendritic cell calcineurin-dependent responses to Aspergillus fumigatus via Stat3 to Stat1 switching by Amit Adlakha, Thomas J. Williams, Xinxin Shou, Anna K. Reed, Boris Lenhard, Darius Armstrong-James

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Semen quality and fertility effectiveness of cloned buffalo (Bubalus bubalis) bulls by Manoj Kumar Singh, Smiriti Gupta, Kanika Gandhi, S.S. Lathwal, Naresh L. Selokar

“…When these spermatozoa were subjected to a transcriptomics study, 27,481 transcripts were identified, out of which 18,703 transcripts were expressed commonly in both cloned and somatic cell donor bull’s spermatozoa. …”
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Structural variant allelic heterogeneity in MECP2 duplication syndrome provides insight into clinical severity and variability of disease expression by Davut Pehlivan, Jesse D. Bengtsson, Sameer S. Bajikar, Christopher M. Grochowski, Ming Yin Lun, Mira Gandhi, Angad Jolly, Alexander J. Trostle, Holly K. Harris, Bernhard Suter, Sukru Aras, Melissa B. Ramocki, Haowei Du, Michele G. Mehaffey, KyungHee Park, Ellen Wilkey, Cemal Karakas, Jesper J. Eisfeldt, Maria Pettersson, Lynn Liu, Marwan S. Shinawi, Virginia E. Kimonis, Wojciech Wiszniewski, Kyle Mckenzie, Timo Roser, Angela M. Vianna-Morgante, Alberto S. Cornier, Ahmed Abdelmoity, James P. Hwang, Shalini N. Jhangiani, Donna M. Muzny, Tadahiro Mitani, Kazuhiro Muramatsu, Shin Nabatame, Daniel G. Glaze, Jawid M. Fatih, Richard A. Gibbs, Zhandong Liu, Anna Lindstrand, Fritz J. Sedlazeck, James R. Lupski, Huda Y. Zoghbi, Claudia M. B. Carvalho

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Cyclin-dependent kinases (CDKs) are key genes regulating early development of Neptunea arthritica cumingii: evidence from comparative transcriptome and proteome analyses by Fengxiao Lv, Xinfan Ge, Yaqing Chang, Zhenlin Hao

“…Furthermore, our results provide theoretical guidance for advancing artificial breeding technology for N. cumingii.…”
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Feeding Behavior, Gut Microbiota, and Transcriptome Analysis Reveal Individual Growth Differences in the Sea Urchin <i>Strongylocentrotus intermedius</i> by Qi Ye, Chuang Gao, Haoran Xiao, Shuchao Ruan, Yongjie Wang, Xiaonan Li, Yaqing Chang, Chong Zhao, Heng Wang, Bing Han, Jun Ding

“…Variations in phagosomes and signaling pathways indicated that size differences are linked to disparities in energy expenditure and stress responses. These findings provide a foundation for future investigations into the regulatory mechanisms underlying growth differences in <i>S. intermedius</i> and provide clues for the screening of molecular markers useful to improve sea urchin production.…”
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