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881
Exploring Gene Expression and Alternative Splicing in Duck Embryonic Myoblasts via Full-Length Transcriptome Sequencing
Published 2024-11-01“…Additionally, we constructed a protein–protein interaction network that highlighted critical regulators—<i>MYOM3</i>, <i>MYL2</i>, <i>MYL1</i>, <i>TNNI2</i>, and <i>ACTN2</i>—associated with the processes of proliferation and differentiation in myoblasts. This extensive transcriptomic investigation not only sheds light on the intricate molecular mechanisms driving skeletal muscle development in ducks but also provides significant insights for future breeding strategies aimed at enhancing the efficiency of duck production. …”
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882
Comparative transcriptome profile analysis of granulosa cells from porcine ovarian follicles during early atresia
Published 2024-12-01“…Additionally, the interaction network of DEGs (p < 0.01; FDR < 0.05) using STRING highlighted LHR, ACACB, and CXCR4 as central nodes. In summary, this transcriptome analysis enriched our knowledge of the shifted mechanisms in granulosa cells during early atresia and provided novel perspectives into the atresia initiation.…”
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883
Effect of different pruning operations on the plant growth, phytohormones and transcriptome profiles of the following spring tea shoots
Published 2022-01-01“…The effects of different pruning operations on the plant growth, phytohormones and transcriptome profiles of the following spring tea shoots were studied. …”
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884
Integrated Transcriptome and Metabolome Analysis Reveals Candidate Genes and Regulatory Pathways Shaping Duck Meat Color
Published 2025-05-01“…To explore the molecular mechanisms affecting duck pectoralis meat color, the phenotypic traits of Cherry Valley duck (CV, eight males and eight females) and Huai Fu duck (HF, eight males and eight females) were compared; three males and three females of each variety were later selected for transcriptomic and metabolomic analyses to reveal key molecular processes. …”
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885
Potential antibacterial effects and transcriptomic analysis of a novel reversible photoacid-based crystalline coordination polymer
Published 2025-07-01“…SEM revealed that the material disrupted cell membrane integrity, leading to cell death. Transcriptomic analysis showed that the material inhibited bacterial protein synthesis, disrupted cell membrane protein synthesis, and downregulated oxidative stress-related genes, causing ROS accumulation and inhibiting cell growth.DiscussionThese findings provide a theoretical basis for the potential clinical application of this material as a new antibacterial agent. …”
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886
Integrating transcriptomic data with a novel drug efficacy prediction model for TCM active compound discovery
Published 2025-03-01“…In addition, biological experiments are directly used to demonstrate that Meta-DEP can mined active compound from traditional Chinese medicine with integrating disease transcriptomic data. Overall, the model developed in this study provides new impetus for driving the natural compound into innovative lead molecule. …”
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887
The Transcriptomic Signature of Donkey Ovarian Tissue Revealed by Cross-Species Comparative Analysis at Single-Cell Resolution
Published 2025-06-01“…Collectively, these findings provide a comprehensive characterization of ovarian cell-type conservation and species-specific adaptations, offering key molecular insights into the mechanisms underlying cross-species differences in reproductive efficiency.…”
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888
Transcriptomics as an Early Warning of Domoic Acid Exposure in Pacific Razor Clams (<i>Siliqua patula</i>)
Published 2025-04-01“…Targeting these genes in real-time PCR assays may provide an early warning system for routine monitoring of DA in clams. …”
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889
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890
Transcriptome and Metabolome Analysis of the Leaf Colour Mutation Mechanism in a Light-Green Leaf Mutant of Maize
Published 2025-05-01“…Through integrated transcriptomic and metabolomic profiling, we identified differentially expressed genes (DEGs) and differentially abundant metabolites associated with the <i data-eusoft-scrollable-element="1">zmpgl</i> phenotype. …”
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891
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892
Effects of Geraniol on Survival, Reproduction, Endophytes, and Transcriptome of Tea Green Leafhoppers (<i>Empoasca onukii</i>)
Published 2025-03-01“…This study enhances our understanding of the insect-resistant mechanisms of HIPVs and provides new insights into environmentally sustainable pest management strategies for tea plantations.…”
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893
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894
Transcriptomic profile of the northern hard clam (Mercenaria mercenaria) in response to short-term low salinity exposure
Published 2025-05-01“…RNA sequencing data from either gill tissue (adults) or pooled whole-body tissue (juveniles) were used to assess the transcriptomic response of clams to short-term low salinity stress. …”
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895
Characterization of canine tumor-infiltrating leukocyte transcriptomic signatures reveals conserved expression patterns with human osteosarcoma
Published 2025-02-01“…Through computational analysis we investigated the differences in cell type proportions and how the OS TME impacted infiltrating immune cell transcriptomic profiles relative to circulating leukocytes. …”
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896
Stage-Specific Transcriptomic Insights into Seed Germination and Early Development in <i>Camellia oleifera</i> Abel.
Published 2025-07-01“…In this study, we examined transcriptomic and physiological changes across five defined germination stages (G0–G4), from radicle dormancy to cotyledon emergence. …”
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897
Integrating transcriptome and metabolomics revealed the key metabolic pathway response of Amaranthus retroflexus L. to the resistance to fomesafen.
Published 2025-01-01“…Therefore, comprehensive analysis of transcriptome and metabolome is needed to determine the key metabolic pathways and key genes of Amaranthus retroflexus L.…”
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898
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899
Analysis of immune infiltration in basal cell carcinoma based on transcriptome sequencing and experimental validation of diagnostic biomarkers
Published 2025-05-01“…Methods Differentially expressed genes (DEGs) were identified from the transcriptome data of 30 BCC patients and 16 controls from the GSE7553, GSE103439, and GSE42109 datasets. …”
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900
Identification of druggable targets in acute kidney injury by proteome- and transcriptome-wide Mendelian randomization and bioinformatics analysis
Published 2025-03-01“…Expression patterns of these targets were examined using bulk transcriptome and single-cell transcriptome data. In addition, drug repurposing analyses were conducted to explore the potential of existing medications. …”
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