Genetic mechanisms of hemispheric functional connectivity in diabetic retinopathy: a joint neuroimaging and transcriptomic study by Xin Huang, Yu-Xuan He, Song Wan

“…Spatial transcriptomic-neuroimaging associations were examined using AHBA, revealing genes significantly correlated with VMHC alterations. …”
Get full text

Combining metabolomics and transcriptomics to study selenium response mechanisms in germinating watermelon seeds (Citrullus mucospermus) by Xiaolong Zhou, Yuehui Wang, Huixing Liang, Shuai Chen, Wenping Ding, Kun Zhuang

Get full text

Comparative Transcriptome Profiling Reveals Changes of microRNAs Response to Exercise in Rats with Neuropathic Pain by Jia-Bao Guo, Bing-Lin Chen, Ge Song, Yi-Li Zheng, Yi Zhu, Zheng Yang, Xuan Su, Ying Wang, Qing Cao, Pei-Jie Chen, Xue-Qiang Wang

“…Therefore, we aimed to explore the changes of miRNA and mRNA of dorsal root ganglion (DRG) after NP in response to exercise with transcriptome technology. The chronic constriction injury (CCI) model was established, and rats were randomly allocated into three groups, namely, the sham-operated, CCI, and CCI-exercised groups. …”
Get full text

Effects of Different Modified Biochars on Growth of <i>Kosteletzkya virginica</i> and Corresponding Transcriptome Analysis by Hao Dai, Mingyun Jia, Jianhui Xue, Yuying Huang, Jinping Yu

Get full text

Molecular Mechanism of <i>Cuscuta</i> Haustorium Specialization Inferences from Transcriptome and Metabolome Analysis by Xingpan Meng, Ning Lv, Xinglin Wang, Qihang Zhou, Xu Zhang, Ximin Zhang, Zhengdong Zhang, Lunxian Liu, Tie Shen

“…Var Williams</i>) through comprehensive transcriptomic and metabolomic analyses. Results: The results demonstrated significant differences in the gene expression and metabolic features between the haustorium and the distal stem segments. …”
Get full text

Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes by Mikiyo Weber, Daniel Fuchs, Amiskwia Pöschel, Erin Beebe, Zuzana Garajova, Armin Jarosch, Laura Kunz, Witold Wolski, Lennart Opitz, Franco Guscetti, Mirja C. Nolff, Enni Markkanen

Get full text

Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata by Jesus Gay-Mimbrera, Pedro Jesús Gómez-Arias, Pedro Jesús Gómez-Arias, Pablo Álvarez-Heredia, Alexander Batista-Duharte, Irene Rivera-Ruiz, Macarena Aguilar-Luque, Miguel Juan-Cencerrado, Miguel Juan-Cencerrado, Carmen Mochón-Jiménez, Carmen Mochón-Jiménez, Álvaro Cebrián-García, Eloísa Andújar-Pulido, Mónica Pérez-Alegre, Alejandra Pera, Alejandra Pera, Juan Ruano, Juan Ruano, Juan Ruano

“…Pseudotime and transcription factor analyses indicated altered differentiation trajectories, and inferred cell-cell communication networks highlighted monocytes, NK cells, and memory T cells as key signaling hubs.DiscussionOur results provide the first integrated single-cell chromatin and transcriptomic map of peripheral immune dysregulation in AA. …”
Get full text

Integration of histology, transcriptome and metabolome reveals the effect of cold stress on the liver of cobia (Rachycentron canadum) by Xiaolong Zhao, Yu Li, Qian Ma, Jiansheng Huang, Jiandong Zhang, Gang Chen

“…To investigate its response to cold stress, histological, transcriptomic, and metabolomic analyses of the liver were conducted. …”
Get full text

Identification of genetic factors influencing flavonoid biosynthesis through pooled transcriptome analysis in mungbean sprouts by Yeonghun Cho, Hakyung Kwon, Hakyung Kwon, Byeong Cheol Kim, Donghwan Shim, Jungmin Ha, Jungmin Ha

“…By combining the results of the secondary metabolite and transcriptome data, we identified six key genes encoding four enzymes (CCoAOMT1; Caffeoyl-CoA O-methyltransferase, CYP81E1; 4'-methoxyisoflavone 2'-hydroxylase, DFR; dihydroflavonol-4-reductase, and HCT; shikimate O-hydroxycinnamoyltransferase) that commonly influence the content of secondary metabolites (catechin, chlorogenic acid, formononetin, and genistin) in mungbeans. …”
Get full text

Physiological, biochemical, and transcriptomic responses to waterlogging stress in Panicum bisulcatum, an emerging weed in rice fields by Jinqiu Sun, Xiaoyue Yu, Yongjie Yang, Hongxing Xu, Mengjie Liu, Zhongxian Lü, Wei Tang

“…Conclusion This study provides valuable information for unrevealing the adaptive mechanisms of P. bisulcatum under waterlogging conditions and helps developing strategies for the management of P. bisulcatum in rice fields.…”
Get full text

Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC by Yongsheng Li, Zhilong Ding, Tingxin Cheng, Yihuai Hu, Fei Zhong, Shiying Ren, Shiyan Wang

Get full text

Transcriptome and metabolome analysis reveals different photosynthetic characteristics of mulberry trees with different ploidy levels by Dan Liu, Qiang Lin, Sheng Huang, Rongli Mo, Xiaomei Lu, Yanrong Zeng, Guangshu Zhu, Chaohua Zhang, Changyu Qiu

“…We compared the microstructural features and transcriptomes of triploid and diploid mulberry trees. …”
Get full text

Transcriptome Insights into Resistance Mechanisms Against Soybean Mosaic Virus Strain SC4 in Soybean by Muhammad Muzzafar Raza, Huiying Jia, Shengyu Gu, Junyi Gai, Kai Li

Get full text

Flu‐CED: A comparative transcriptomics database of influenza virus‐infected human and animal models by Yue Wu, Jue Wang, Jing Xue, Zhiguang Xiang, Jianguo Guo, Lingjun Zhan, Qiang Wei, Qi Kong

“…Abstract Background The continuing emergence of influenza virus has highlighted the value of public databases and related bioinformatic analysis tools in investigating transcriptomic change caused by different influenza virus infections in human and animal models. …”
Get full text

Comparative transcriptome profiling reveals that light coordinates auxin to inhibit adventitious root formation in grapevine by Yunzhang Yuan, Miao Bai, Peiyi Ni, Yanxia Li, Xinyu Chang, Jingjing He, Guoshun Yang, Shuangjiang Li

“…LP samples under light and dark conditions were used for transcriptome sequencing and endogenous hormone measurements at three critical time points of AR formation. …”
Get full text

Transcriptome analysis of Colletotrichum nymphaeae-Strawberry interaction reveals in planta expressed genes associated with virulence by Egem Ozbudak, Egem Ozbudak, Yisel Carrillo-Tarazona, Edinson A. Diaz, Flavia T. Zambon, Lorenzo Rossi, Natalia A. Peres, Sylvain Raffaele, Liliana M. Cano

“…Understanding the transcriptomic responses of C. nymphaeae during infection can provide critical insights into its pathogenic mechanisms. …”
Get full text

Integrated transcriptomic and metabolomic analysis of goose epididymis reveals molecular markers associated with sperm mobility by Xiaofang Ren, Ke Jiang, Jiaxin Yin, Zhigang Ma, Zhifeng Chen, Kun Yang, Shengjun Liu

“…In conclusion, this study provides novel insights into the molecular mechanisms regulating SM in the epididymis and lays a theoretical foundation for geese breeding programs.…”
Get full text

Unraveling the Amino Acid Synthesis in Maturity Sesame Seeds Based on the Integrative Analysis of Transcriptome and Metabolome by Yinping Zhang, Yuanyuan Zhang, Xiangyu Zhou, Nan Yang, Duoqi Zhou, Kiran Thakur, Qiang Wang, Carlos L. Cespedes‐Acuña, Haiyang Zhang, Hongmei Miao, Zhaojun Wei

“…To unravel these mechanisms, we analyzed the metabolome and transcriptome profiles of a sesame variety across four distinct growth stages (S1–S4). …”
Get full text

Integration of transcriptome and DNA methylome analysis reveals the molecular mechanism of taproot yield heterosis in radish by Xiaoli Zhang, Liang Xu, Yan Wang, Wei Zhang, Xinyu Zhang, Junhui Dong, Jiali Ying, Lun Wang, Yinbo Ma, Liwang Liu

“…Nevertheless, the molecular mechanism underlying the formation of heterosis in radish remains unclear. Herein, both the transcriptome and DNA methylome analyses were performed on the F1 hybrids and parental lines. …”
Get full text

Single-cell transcriptomics unveils leukocyte heterogeneity in the gills of Larimichthys crocea in response to parasitic infection by Qiuhua Li, Qiuhua Li, Meiyan Wang, Chenhao Li, Ngoc Tuan Tran, Jingqun Ao, Shengkang Li, Xinhua Chen

Get full text