Single-cell technologies and spatial transcriptomics: decoding immune low - response states in endometrial cancer by Yumeng Li, Hua Qiu, Zhenzhen Zhao, Fanghua Qi, Pingping Cai

“…Globally, endometrial cancer continues to impact a significant number of women. Immunotherapy provides those suffering from advanced or relapsed disease hope, but an important barrier is still the absence of trustworthy predictive biomarkers. …”
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Identification of ligand and receptor interactions in CKD and MASH through the integration of single cell and spatial transcriptomics. by Jaime Moreno, Lise Lotte Gluud, Elisabeth D Galsgaard, Henning Hvid, Gianluca Mazzoni, Vivek Das

“…Combining single-cell (scRNAseq) and spatial transcriptomics (ST) could give unprecedented molecular disease understanding at single-cell resolution. …”
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Comprehensive transcriptome and proteome analysis revealed the molecular mechanisms of melatonin priming and waterlogging response in peach by Xianbin Gu, Linghong Lu, Jing Gao, Fei Fan, Genhua Song, Huiqin Zhang

“…Transcriptome analysis implicated genes related to ‘DNA-binding transcription factor activity’, such as AP2/ERF, HSF and WRKY transcription factors, in response to waterlogging. …”
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Integrating metabolomics and transcriptomics comprehensively reveals the global metabolic differences in three species of Nitraria berries by Yanhong Li, Shengyan Wang, Qing Zhao, Qian Wang, Zufan Yang, Qiangqiang Jia

“…This study combined metabolomics and transcriptomics to explore the differences among three species of Nitraria berries. …”
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Non-Metastatic Pure Pancreatic Hepatoid Carcinoma with Genomic and Transcriptomic Analysis: A Case Report by Subin Punnen, Veronika Csizmok, Connor Frey, Richard Gilbert, David F. Schaeffer, Stephen Yip, Marco A. Marra, Janessa Laskin, Michael Bleszynski, Daniel R. Owen

“…Data on its management and genomic findings are limited, and further characterization may provide helpful information in caring for these patients. …”
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Physiological Changes and Time-Course Transcriptomic Analysis of Salt Stress in <i>Chenopodium quinoa</i> by Peipei Li, Yemeng Zhang

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Deciphering the tumor immune microenvironment: single-cell and spatial transcriptomic insights into cervical cancer fibroblasts by Zhiheng Lin, Youwei Zhou, Zhenran Liu, Wenyang Nie, Hengjie Cao, Shengnan Li, Xuanling Li, Lijun Zhu, Guangyao Lin, Yanyu Ding, Yi Jiang, Zuxi Gu, Lianwei Xu, Zhijie Zhao, Huabao Cai

“…This study integrates single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and deconvolution analysis to identify key genes and immunotherapy targets. …”
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Combined analysis of the metabolome and transcriptome reveals the mechanism of Red heart Chinese fir heartwood formation by Cuiping Li, Kaiyong Huang, Kuipeng Li

“…To uncover the mechanism of heartwood formation for Red-heart Chinese fir, we conducted a combined analysis of the metabolome and transcriptome during the radial alteration of mature Red-heart Chinese fir xylem. …”
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Neuroanatomical and functional substrates of the short video addiction and its association with brain transcriptomic and cellular architecture by Yuanyuan Gao, Ying Hu, Jinlian Wang, Chang Liu, Hohjin Im, Weipeng Jin, Wenwei Zhu, Wei Ge, Guang Zhao, Qiong Yao, Pinchun Wang, Manman Zhang, Xin Niu, Qinghua He, Qiang Wang

“…We investigated the neuroanatomical and functional substrates of SVA symptoms, alongside brain transcriptomic and cellular characteristics, using Inter-Subject Representational Similarity Analysis (IS-RSA) and transcriptomic approaches. …”
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Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics by Shreya Johri, Kevin Bi, Breanna M. Titchen, Jingxin Fu, Jake Conway, Jett P. Crowdis, Natalie I. Vokes, Zenghua Fan, Lawrence Fong, Jihye Park, David Liu, Meng Xiao He, Eliezer M. Van Allen

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Single-Cell Transcriptomic Dataset of RPGR-associated Retinitis Pigmentosa Patient-Derived Retinal Organoids by Ting Li, Yuting Ma, Yun Cheng, Yingke Zhao, Zhixu Qiu, Hongli Liu, Daowei Zhang, Jiawen Wu, Junfeng Li, Shenghai Zhang, Jihong Wu

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Transcriptomic reveals key genes and regulatory pathways in galactomannan biosynthesis in Gleditsia sinensis polysaccharide gum by Yanyan Zhang, Tingting Yang, Xiangpei Wang, Feng Xu, Linlin Du, Hongmei Wu

“…Further pathway enrichment analysis demonstrated that fructokinase, galactose gyrase, inositol galactoside synthase, phosphogalactosyltransferase, and raffinose synthase play pivotal roles in GM biosynthesis, positively regulating its production.DiscussionThe results of this study provide new ideas for the research of GM biosynthesis related genes in G. sinensis and enhance the potential application prospects in genetic engineering.…”
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Comprehensive transcriptome analysis of developing xylem responding to artificial bending and gravitational stimuli in Betula platyphylla. by Chao Wang, Nan Zhang, Caiqiu Gao, Zhiyuan Cui, Dan Sun, Chuanping Yang, Yucheng Wang

“…In addition, fasciclin-like arabinogalactan proteins play important role in TW formation. These findings may provide important insights into wood formation at the molecular level.…”
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Detecting significant expression patterns in single-cell and spatial transcriptomics with a flexible computational approach by Hadas Biran, Tamar Hashimshony, Tamar Lahav, Or Efrat, Yael Mandel-Gutfreund, Zohar Yakhini

“…Data analysis for spatial transcriptomics mostly addresses clustering and finding spatially variable genes. …”
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Characterization of the miiuy croaker (Miichthys miiuy) transcriptome and development of immune-relevant genes and molecular markers. by Rongbo Che, Yueyan Sun, Dianqiao Sun, Tianjun Xu

“…<h4>Conclusion</h4>The miiuy croaker (Miichthys miiuy) transcriptome data provides a large resource to identify new genes involved in many processes including those involved in the response to pathogens and diseases. …”
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Comparative Transcriptome Analysis of Recessive Male Sterility (RGMS) in Sterile and Fertile Brassica napus Lines. by Cunmin Qu, Fuyou Fu, Miao Liu, Huiyan Zhao, Chuan Liu, Jiana Li, Zhanglin Tang, Xinfu Xu, Xiao Qiu, Rui Wang, Kun Lu

“…Some of the genes identified in this study are candidates for future research, as they could provide important insight into the molecular mechanisms underlying RGMS in WSLA.…”
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Color-induced changes in Chrysanthemum morifolium: an integrative transcriptomic and metabolomic analysis of petals and non-petals by Jianhong Wei, Zhaoxiang Zeng, Chengwu Song, Chengwu Song, Qing Lv, Guangya Chen, Guoyan Mo, Guoyan Mo, Ling Gong, Shuna Jin, Shuna Jin, Rongzeng Huang, Rongzeng Huang, Bisheng Huang, Bisheng Huang

“…These findings offer critical insights into the molecular mechanisms governing CM coloration and provide a foundation for optimizing future breeding efforts.…”
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Comprehensive full-Length transcriptomic resource for wing dimorphism in English green aphid, Sitobion avenae by Yi Yan, Qiuting Lv, Guohua Wei, Yaxin Gu, Linyuan Wu, Cong Zhang, Yunhui Zhang, Xun Zhu, Xuguo Zhou, Xiangrui Li

“…To support research and data sharing on the molecular basis of this trait, we generated full-length transcriptomes from three different developmental stages of winged and wingless morphs using PacBio SMRT and Illumina HiSeq sequencing platforms. …”
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In depth transcriptomic profiling defines a landscape of dysfunctional immune responses in patients with VEXAS syndrome by Hiroki Mizumaki, Shouguo Gao, Zhijie Wu, Fernanda Gutierrez-Rodrigues, Massimiliano Bissa, Xingmin Feng, Emma M. Groarke, Haoran Li, Lemlem Alemu, Diego Quinones Raffo, Ivana Darden, Sachiko Kajigaya, Peter C. Grayson, Genoveffa Franchini, Neal S. Young, Bhavisha A. Patel

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Transcriptome reveal gene regulation mechanisms of the barnacle Chthamalus challengeri for microhabitat adaption in the intertidal zone by HaoYuan Li, MengMeng Huang, ZhiBin Gan, XinZheng Li

“…Results In this study, we designed a series of in situ tidal conditions for C. challengeri and sequenced their transcriptome collected from various microhabitats. We aimed to detect the genetic adaptation mechanisms of barnacles responding to the microhabitat changes in the intertidal zone based on comparative transcriptomics. …”
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