Biopsy-Based Transcriptomics Support Rejection Monitoring Through Repeated Kidney Allograft Biopsies by Lukas Weidmann, Dusan Harmacek, Ariana Gaspert, Birgit Maria Helmchen, Britta George, Kerstin Hübel, Seraina von Moos, Elena Rho, Thomas Schachtner

“…Conclusions: Biopsy-based transcriptomics differentiated suspicious molecular signals among histologically “rejection-free” biopsies progressing to rejection and provided a monitoring tool after antirejection treatment interventions.…”
Get full text

Identification of novel biomarkers and prognostic model for neuroblastoma using Mendelian randomization and transcriptomic analysis by Yongcheng Fu, Nan Zhang, Jian Cheng, Xiaohan Qin, Xing Zhou, Xiaoran Du, Yuanyuan Wang, Jingyue Wang, Da Zhang

Get full text

Whole transcriptome sequencing to uncover CircRNA expression patterns linked to schizophrenia pathogenesis by Jianxiong Long, Bing Shen, Fangping Liao, Hong Cai, Jiale Li, Rumei Lu, Zhicheng Zhong, Zukang Gong, Jianfeng Xu

“…Abstract Background No objective diagnostic indicators have been identified for schizophrenia (SCZ) because of the complexity of its pathogenesis. Whole-transcriptome analysis may help identify early diagnostic markers. …”
Get full text

Aspirin Eugenol Ester Modulates the Hypothalamus Transcriptome in Broilers Under High Stocking Density by Xiaodie Zhao, Yi Zhang, Dongying Bai, Wenrui Zhen, Caifang Guo, Ziwei Wang, Penghui Ma, Xiqiang Ma, Xiaolin Xie, Koichi Ito, Bingkun Zhang, Yajun Yang, Jianyong Li, Yanbo Ma

“…Thus, the current study provides new insights into hypothalamic transcription patterns that are associated with the ameliorative effects of AEE in HD broilers.…”
Get full text

Single Cell and Transcriptomic Analysis of Regulatory Mechanisms of Key Genes in Systemic Lupus Erythematosus by Zhou Y, Wu Y, Yang B, Zhu Q, Long H, Yuan L, Cao W, Deng D

“…Our findings offer new insights into SLE mechanisms and provide a theoretical basis for developing targeted therapeutic strategies.Keywords: systemic lupus erythematosus, immune cell, key gene, single-cell analysis…”
Get full text

Dynamic distribution and temporal transcriptome adaptations elucidate lithium accumulation pattern in Cardamine violifolia by Lulu Chen, Mingwei Yue, Xiaomeng Liu, Xin Cong, Shuiyuan Cheng, Shen Rao

“…By integrating physiological, biochemical, and transcriptomic analyses, we identified multiple gene families associated with Li transport in plants. …”
Get full text

Transcriptome analysis of jejunal mucosal tissue in breeder hens exposed to acute heat stress by Yongcai Zhu, Satoshi Kubota, Phocharapon Pasri, Sitthipong Rakngam, Supattra Okrathok, Chayanan Pukkung, Shenglin Yang, Sutisa Khempaka

“…Transcriptome analysis revealed 138 genes with altered expression patterns under acute HS conditions. …”
Get full text

Integrative single‐cell transcriptomic analysis deciphers heterogeneous characteristics of gastrointestinal tract cancer by Chuwen Sun, Tong Li, Xin Jin, Zhihui Xiu, Hang Su, Huanming Yang, Ming Liu, Kui Wu

Get full text

Exploring the Shared Genetic Characteristics of Peri-Implantitis and Osteoporosis: A Transcriptomic Analysis Perspective by Churen Zhang, Feixiang Wang, Jianguo Ke, Cuihong Lin, Xiaohua Zeng, Qiuyan Yang, Qiaoling Cai

“…Conclusion: This study provides valuable insights into the molecular mechanisms underlying peri-implantitis and osteoporosis, highlighting the potential for further investigation into targeted therapies that may improve clinical outcomes for affected patients. …”
Get full text

Transcriptome and metabolome analysis of the responses of salt resistance of different Helianthus annuus germplasms to melatonin by Changyan Zhao, Changyan Zhao, Yantao Liu, Xiuping Jia, Shengli Liu, Peng Wang, Zhifeng Zhu, Sumei Wan, Wei Duan

“…This study will advance understanding of mechanism by which melatonin enhances salt resistance of H. annuus, and provide a scientific basis for the breeding of saltresistant H. annuus cultivars.…”
Get full text

Transcriptome analysis of Aedes aegypti midgut and salivary gland post-Zika virus infection by Chunling Zhu, Yuting Jiang, Qianghui Zhang, Jian Gao, Chaojie Li, Chunxiao Li, Yande Dong, Dan Xing, Hengduan Zhang, Teng Zhao, Xiaoxia Guo, Tongyan Zhao

“…Our findings demonstrate that Ae. aegypti exhibit distinct transcriptomic changes in response to ZIKV infection. …”
Get full text

Transcriptome profiling of Anoectochilus roxburghii L. reveals spermidine-mediated response to drought stress by Muhammad Waheed Riaz, Qingjun Zou, Ailian Zhang, Aicun Zhou, Muhammad Yasir, Chunqing Chen, Ying Zheng, Qingsong Shao

“…Moreover, qRT-PCR results further confirmed the RNA-seq results. This study provides the first report of transcriptomic data for A. roxburghii plants under drought stress and exogenous spermidine application. …”
Get full text

Transcriptome analysis reveals the mechanism of mixed oligosaccharides in the response of rice seedlings to abiotic stresses by Yanan Xu, Yanan Xu, Yigang Yang, Yeran Bai, Makoto Saito, Wei Han, Yuanpei Zhang, Guohua Lv, Jiqing Song, Wenbo Bai

“…KP-priming treatment significantly enhanced leaf photosynthetic capacity through promoting photosynthetic pigments and maximum photochemical efficiency by 2.34–135.76%, and enhancing leaf stomatal aperture by 21.58–75.84%. Transcriptomic analysis revealed that differentially expressed genes in response to KP-priming under salt and alkaline stresses were predominantly associated with photosynthetic pathways. …”
Get full text

Transcriptomic Insights into the Protective Effects of Apigenin and Sodium Butyrate on Jejunal Oxidative Stress in Ducks by Ning Zhou, Hanxue Sun, Yong Tian, Heng Zhang, Xuemei Xian, Hui Yu, Lingyan Zhao, Yong Chen, Mingkun Sun, Yiqian Zhang, Ting Meng, Lizhi Lu

“…This study evaluated the jejunal transcriptomic responses in ducks receiving apigenin and sodium butyrate supplementation under oxidative stress. …”
Get full text

Spatial transcriptomic differences in the breast muscle of grower broilers at 21 and 28 days of age by Janghan Choi, Jihwan Lee, Doyun Goo, Gippeum Han, Venkata Sesha Reddy Choppa, Seshidhar Reddy Gudidoddi, Majid Shakeri, Hong Zhuang, Brian Bowker, Woo Kyun Kim, Byungwhi Kong

“…Understanding these spatial transcriptomic differences may provide insights into identifying etiologies and developing strategies for breast myopathies.…”
Get full text

QTL mapping provides new insights into emamectin benzoate resistance in salmon lice, Lepeophtheirus salmonis by Armin Sturm, Greta Carmona-Antoñanzas, Joseph L. Humble, Claudia Croton, Sally Boyd, Rapule Mphuti, John B. Taggart, David I. Bassett, Ross D. Houston, Karim Gharbi, James E. Bron, Michaël Bekaert

Get full text

Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation by Sara Kirmani, Tianxiao Huan, Joseph C. Van Amburg, Roby Joehanes, Md Mesbah Uddin, Ngoc Quynh H. Nguyen, Bing Yu, Jennifer A. Brody, Myriam Fornage, Jan Bressler, Nona Sotoodehnia, David A. Ong, Fabio Puddu, James S. Floyd, Christie M. Ballantyne, Bruce M. Psaty, Laura M. Raffield, Pradeep Natarajan, Karen N. Conneely, Joshua S. Weinstock, April P. Carson, Leslie A. Lange, Kendra Ferrier, Nancy L. Heard-Costa, Joanne Murabito, Alexander G. Bick, Daniel Levy

Get full text

Evolutionary Dynamics of Glycoside Hydrolase Family 1 Provide Insights into Insect–Plant Interactions in Lepidoptera by Yanping Yuan, Xidan Zhang, Jinyu Wu, Jun Li, Zhengbo He, Wenbo Fu, Amrita Chakraborty, Shulin He

“…Overall, this study provides comprehensive insights into the evolutionary trajectories of <i>GH1</i> genes, highlighting their potential contribution to insect–plant interactions in Lepidoptera.…”
Get full text

Multifaceted investigations of PSMB8 provides insights into prognostic prediction and immunological target in thyroid carcinoma. by Yulou Luo, Yinghui Ye, Yilina Saibaidoula, Yuting Zhang, Yan Chen

Get full text

Insights into the roles of exogenous phenylalanine and tyrosine in improving rapamycin production of Streptomyces rapamycinicus with transcriptome analysis by Dongmei Xu, Yaoyao Wang, Hongzhen Li, Bing Wang, Libin Chai, Li Feng, Fengzhi Ren, Xuejin Zhao, Xuexia Zhang

“…To gain insight into the mechanism of rapamycin overproduction, comparative transcriptomic profiling was performed between media with and without phenylalanine and tyrosine addition. …”
Get full text