Metabolome and transcriptome analysis reveal the effect of methyl jasmonate on phytosterol biosynthesis in Brassica napus by Xueyan Wang, Min Liu, Ruinan Yang, Xiaobo Cui, Jie Liu, Yu Zhang, Yizhou He, Li Yu, Fei Ma, Xiong Zhang, Yuanyuan Zhang, Shengyi Liu, Peiwu Li, Liangxiao Zhang

“…Overall, this study provides valuable insights into the phytosterol biosynthesis in rapeseed and offers a simple and effective approach for improving rapeseed quality.…”
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Single-cell transcriptomic dynamics of scallop heart reveals the heterogeneous response to heat stress by Danyang Wang, Na Liu, Xiangfu Kong, Xinghai Zhu, Yangfan Wang, Jingjie Hu, Zhenmin Bao

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Physiological insights into the responses of tea plants to aluminum through an integrated transcriptomic and metabolomic analysis by Xinwan Zhang, Shijie Luo, Xiali Ye, Lin Liu, Xinxin Jia, Deyuan Jiang, Weiwei Wen

“…Overall, this study provides a comprehensive understanding of effects from Al on tea plant physiology, offering molecular and physiological insights into Al tolerance mechanisms and theoretical bases for optimizing tea cultivation in acidic soils.…”
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Biomarker discovery for non-invasive diagnosis of inflammatory bowel disease using blood transcriptomics by Mohammad Hossein Derakhshan Nazari, Mahsa Ghorbaninejad, Shabnam Shahrokh, Anna Meyfour

“…To enable non-invasive diagnosis, we aimed to identify blood-based transcriptomic biomarkers that specifically distinguish IBD from healthy and inflammatory controls.MethodsPublic microarray and RNA-seq datasets from whole blood of IBD, rheumatoid arthritis (RA), and control subjects were analyzed. …”
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In the battle of survival: transcriptome analysis of hypopharyngeal gland of the Apis mellifera under temperature-stress by Abdulkadir Yusif Maigoro, Jeong Hyeon Lee, Yumi Yun, Sujin Lee, Hyung Wook Kwon

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Transcriptomic profiling reveals response mechanisms of Lactuca indica seedlings to seawater irrigation stress by Dingding Cao, Lirong Xiang, Ziling Li, Neng Wei, Neng Wei, Qingfeng Wang, Qingfeng Wang

“…This study provides the comprehensive tissue-specific transcriptome profile of wild L. indica under seawater irrigation, predicting crucial metabolic pathways and candidate genes that might enhance seawater tolerance. …”
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Effects of 1-MCP on the genes related to wax anabolism in pear peel based on transcriptomics by YU Wanting, ZHANG Xinnan, SUN Xiaonan, WANG Wenhui, JIA Xiaohui

“…RNA was extracted from frozen peel samples every 7 days for transcriptome sequencing and data analysis, and RT-qPCR technology was used to verify the significant difference genes. …”
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Full-length transcriptome analysis of male and female gonads in Japanese Eel (Anguilla japonica) by Jiangling Li, Jingjie Liang, Mengyang Wang, Yuewen Jiang, Wen Li, Mingxi Huang, Yan Huang, Yangjie Xie, Jianchun Chen, Tiansheng Chen

“…Conclusions This study provides valuable insights into the molecular mechanisms of gonadal differentiation and sexual dimorphism in Japanese eels. …”
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Spatial transcriptomic analysis of tumor microenvironment in esophageal squamous cell carcinoma with HIV infection by Yuanli Zuo, Yang Jin, Gang Li, Yue Ming, Ting Fan, Yitong Pan, Xiaojun Yao, Yong Peng

“…Methods We performed spatial transcriptome sequencing on HIV-ESCC samples to depict the microenvironment and employed cell communication analysis and multiplex immunofluorescence to investigate the molecular mechanism in HIV-ESCC. …”
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Transcriptomic and proteomic characterization of cell and protein biomarkers of checkpoint inhibitor-induced liver injury by Changhua Ji, Steven Kumpf, Jessie Qian, Joel D. Federspiel, Mark Sheehan, Darien Capunitan, Edmond Atallah, Stuart Astbury, Seda Arat, Elias Oziolor, Mireia Fernandez Ocana, Shashi K. Ramaiah, Jane Grove, Guruprasad P. Aithal, Thomas A. Lanz

“…PBMCs were sequenced for by transcriptomic and T cell receptor repertoire (bulk and single-cell immune profiling), and extracellular vesicle (EV) enrichment from plasma was analyzed by mass spectroscopy proteomics. …”
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Establishment of somatic embryogenesis regeneration system and transcriptome analysis of early somatic embryogenesis in litchi by Yaqi Qin, Bo Zhang, Shiqian Wang, Wuyan Guo, Zhike Zhang, Yonghua Qin, Jietang Zhao, Guibing Hu

“…Therefore, this study can provide a theoretical basis and technical support for genetic breeding improvement of litchi.…”
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Proinflammatory transcriptomic and kinomic alterations in astrocytes derived from patients with familial Alzheimer's disease by Benjamin Siciliano, Nicholas D. Henkel, William G. Ryan V, Ali Sajid Imami, John M. Vergis, Chongchong Xu, Taylen O. Arvay, Smita Sahay, Priyanka Pulvender, Abdul-rizaq Hamoud, Chadwick Hales, Robert E. McCullumsmith, Zhexing Wen

“…In this study, we employed a multiomic integrative analysis combining transcriptomic and kinomic profiling of human induced pluripotent stem cell (hiPSC)-derived astrocytes from patients with familial AD (fAD) compared to healthy controls (HCs). …”
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Transcriptome analysis reveals the candidate genes associated with skin color variation in Luciobarbus capito by Longwu Geng, Xinchi Shang, Haijun Wei, Guangxiang Tong, Wei Xu, Youyi Kuang

“…To investigate the molecular mechanisms of body color variation in L. capito, we conducted comparative transcriptome analysis on skin samples from two distinct color morphs. …”
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Genetic Adaptations of Soybean to Cold Stress Reveal Key Insights Through Transcriptomic Analysis by Xiulin Liu, Chunlei Zhang, Sobhi F. Lamlom, Kezhen Zhao, Ahmed M. Abdelghany, Xueyang Wang, Fengyi Zhang, Rongqiang Yuan, Dezhi Han, Bire Zha, Wencheng Lu, Honglei Ren, Bixian Zhang

“…The findings showed that increased malondialdehyde levels provided evidence of DS17’s heightened vulnerability to lipid peroxidation and membrane degradation. …”
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Transcriptomic sequencing and differential analysis of Kazakh horse muscles from various anatomical locations by Mierkadina· Wubulikasimu, Jiahao Liu, Xinkui Yao, Xinkui Yao, Jun Meng, Jun Meng, Jianwen Wang, Jianwen Wang, Yaqi Zeng, Yaqi Zeng, Linling Li, Wanlu Ren, Wanlu Ren

“…RT-qPCR analysis validated the accuracy of the transcriptomic sequencing data. This study provides valuable insights into the differential expression of genes and related signaling pathways in various muscle tissues of Kazakh horses, rendering a theoretical foundation and data references for understanding skeletal muscle growth and improving meat production in equines.…”
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Human and mouse platelet transcriptomes and proteomes for phenotyping 3474 genes with hemostatic and platelet traits by Jingnan Huang, Federico Marini, Fiorella A. Solari, Frauke Swieringa, Bas de Laat, Ilaria De Simone, Luigi Grassi, Xiang Gui, Kunpeng Li, Elizabeth A. Middleton, Neil V. Morgan, Isabella Provenzale, Carina Santos, Saskia Schols, Sarah Westbury, Albert Sickmann, Matthew T. Rondina, Wolfram Ruf, Mattia Frontini, Johan W. M. Heemskerk

“…This provided reference levels for 54 790 (54 247) transcripts and 6379 (4563) proteins in human (mouse) platelets. …”
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Deciphering the molecular transcriptomic mechanisms of carbon ion beams and X-ray on rice seedlings by Jianing Ding, Chaoli Xu, Yan Du, Xiao Liu, Jingmin Chen, Zhe Li, Jing Long, Yukun Sheng, Wenjie Jin, Dan Xu, Libin Zhou

“…Conclusion This study offers insights into the molecular transcriptomic mechanisms underlying the impacts of IR on rice seedlings. …”
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Combined metabolomic and transcriptomic analysis reveals the key genes for triterpenoid biosynthesis in Cyclocarya paliurus by Duo Chen, Xupeng Chen, Xuehai Zheng, Jinmao Zhu, Ting Xue

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Long-read transcriptomics of caviid gammaherpesvirus 1: compiling a comprehensive RNA atlas by Gábor Torma, Ákos Dörmő, Ádám Fülöp, Dóra Tombácz, Máté Mizik, Amanda M. Pretory, See-Chi Lee, Zsolt Toth, Zsolt Boldogkői

“…Given its tumorigenic properties, broad host range, and non-human pathogenicity, this work establishes CaGHV-1 as a promising small animal model for investigating human gammaherpesvirus pathogenesis.IMPORTANCEThe molecular underpinnings of gammaherpesvirus pathogenesis remain poorly understood, partly due to limited animal models. This study provides the first comprehensive transcriptomic atlas of CaGHV-1, highlighting both coding and non-coding RNAs and revealing regulatory elements that drive viral gene expression. …”
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Combined transcriptome and metabolome analysis of Polygonatum cyrtonema Hua in response to Botrytis deweyae infection by Fuqiang Yin, Wanli Ma, Wanli Ma, Zhien Xiao, Yuxin Liu, Tiantian Guo, Yue Yuan, Shaotian Zhang, Guoli Li, Ming Liu

“…To investigate the physiological reactions and transcriptome gene changes of P. cyrtonema after B. deweyae infection, in this study, we investigated the defense enzyme activity, transcriptome differential genes (DEGs), and differential metabolites (DAMs) of P. cyrtonema. …”
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